Publications From the Khurana Hershey Lab

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Zhang Z, Biagini Myers JM, Brandt EB, Ryan PH, Lindsey M, Mintz-Cole RA, Reponen T, Vesper SJ, Forde F, Ruff B, Bass SA, LeMasters GK,Bernstein DI, Lockey J, Budelsky AL, Khurana Hershey GK. β-Glucan exacerbates allergic asthma independent of fungal sensitization and promotes steroid-resistant TH2/TH17 responses. J Allergy Clin Immunol. 2016 Apr 20. pii: S0091-6749(16)30084-7. [Epub ahead of print]  

Brandt EB, Khurana Hershey GK. A combination of dexamethasone and anti-IL-17A treatment can alleviate diesel exhaust particle-induced steroid insensitive asthma. J Allergy Clin Immunol. 2016 May 5. pii: S0091-6749(16)30253-6.. [Epub ahead of print]

Gupta J, Johansson E, Bernstein JA, Chakraborty R, Khurana Hershey GK, Rothenberg ME, Mersha TB. Resolving the etiology of atopic disorders by using genetic analysis of racial ancestry. J Allergy Clin Immunol. 2016 Jun 10. pii: S0091-6749(16)30256-1. [Epub ahead of print]

Ulm A, Mayhew CN, Debley J, Khurana Hershey GK, Ji H. Cultivate Primary Nasal Epithelial Cells from Children and Reprogram into Induced Pluripotent Stem Cells. J Vis Exp. 2016 Mar 10;(109). 

Nanda MK, LeMasters GK, Levin L, Rothenberg ME, Assa'ad AH, Newman N, Bernstein D, Khurana-Hershey G, Lockey JE, Ryan PH. Allergic Diseases and Internalizing Behaviors in Early Childhood. Pediatrics. 2016 Jan;137(1):1-10.


Ghosh D, Ding L, Sivaprasad U, Geh E, Biagini Myers J, Bernstein JA, Khurana Hershey GK, Mersha TB. Multiple Transcriptome Data Analysis Reveals Biologically Relevant Atopic Dermatitis Signature Genes and Pathways. PLoS One. 2015 Dec 30;10(12):e0144316. 

Brandt EB, Myers JM, Ryan PH, Hershey GK. Air pollution and allergic diseases. Curr Opin Pediatr. 2015 Dec;27(6):724-35. 

Eiymo Mwa Mpollo MS, Brandt EB, Shanmukhappa SK, Arumugam PI, Tiwari S, Loberg A, Pillis D, Rizvi T, Lindsey M, Jonck B, Carmeliet P, Kalra VK, Le Cras TD, Ratner N, Wills-Karp M, Hershey GK, Malik P. Placenta growth factor augments airway hyperresponsiveness via leukotrienes and IL-13. J Clin Invest. 2015 Dec 21. pii: 77250.

Somineni HK, Zhang X, Biagini Myers JM, Kovacic MB, Ulm A, Jurcak N, Ryan PH, Khurana Hershey GK, Ji H. Ten-eleven translocation 1 (TET1) methylation is associated with childhood asthma and traffic-related air pollution. J Allergy Clin Immunol. 2015 Dec 9. pii: S0091-6749(15)01577-8.

Teach SJ, Gill MA, Togias A, Sorkness CA, Arbes SJ Jr, Calatroni A, Wildfire JJ, Gergen PJ, Cohen RT, Pongracic JA, Kercsmar CM, Khurana Hershey GK, Gruchalla RS, Liu AH, Zoratti EM, Kattan M, Grindle KA, Gern JE, Busse WW, Szefler SJ. Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations. J Allergy Clin Immunol. 2015 Dec;136(6):1476-85.

Klein M, Khurana Hershey GK, Devarajan P, Muglia LJ, Wikenheiser-Brokamp KA, Loch J, Hostetter MK, Strauss AW, DeWitt TG. Enhancing Pediatric Fellows' Research Training: Development of an Office of Pediatric Clinical Fellowships. J Pediatr. 2015 Sep;167(3):506-507.


Brunst KJ, Ryan PH, Brokamp C, Bernstein D, Reponen T, Lockey J, Khurana Hershey GK, Levin L, Grinshpun SA, LeMasters G. Timing and Duration of Traffic-Related Air Pollution Exposure and the Risk for Childhood Wheeze and Asthma. Am J Respir Crit Care Med. 2015 Aug 15;192(4):421-7.

Butsch Kovacic M, Martin LJ, Biagini Myers JM, He H, Lindsey M, Mersha TB, Ji H, Khurana Hershey GK. Genetic Approach Identifies Distinct Asthma Pathways In Overweight vs. Normal Weight Children. Allergy. 2015 Aug;70(8):1028-32.

Xiao C, Biagini Myers JM, Ji H, Metz K, Martin LJ, Lindsey M, He H, Powers R, Ulm A, Ruff B, Ericksen MB, Somineni HK, Simmons J, Strait RT, Kercsmar CM, Khurana Hershey GK. Vanin-1 expression and methylation discriminate pediatric asthma corticosteroid treatment response. J Allergy Clin Immunol. 2015 Mar 28. pii: S0091-6749(15)00261-4. doi: 10.1016/j.jaci.2015.01.045. [Epub ahead of print]

Mersha TB, Martin LJ, Biagini Myers JM, Kovacic MB, He H, Lindsey M, Sivaprasad U, Chen W, Khurana Hershey GK. Genomic Architecture of Asthma Differs by Sex. Genomics. 2015 Mar 25. pii: S0888-7543(15)00051-8. doi: 10.1016/j.ygeno.2015.03.003. [Epub ahead of print]

Liu B, Lee JB, Chen CY, Hershey GK, Wang YH. Collaborative Interactions between Type 2 Innate Lymphoid Cells and Antigen-Specific CD4+ Th2 Cells Exacerbate Murine Allergic Airway Diseases with Prominent Eosinophilia. J Immunol. 2015 Mar 16. pii: 1400951. [Epub ahead of print]

Brandt EB, Biagini Myers JM, Acciani TH, Ryan PH, Sivaprasad U, Ruff B, LeMasters GK, Bernstein DI, Lockey JE, LeCras TD, Khurana Hershey GKExposure to allergen and diesel exhaust particles potentiates secondary allergen-specific memory responses, promoting asthma susceptibility. J Allergy Clin Immunol. 2015 Mar 3. pii: S0091-6749(15)00094-9. doi: 10.1016/j.jaci.2014.11.043. [Epub ahead of print]

Codispoti CD, Bernstein DI, Levin L, Reponen T, Ryan PH, Biagini Myers JM, Villareal M, Burkle J, Lummus Z, Lockey JE, Khurana Hershey GK, LeMasters GK.  Early-life mold and tree sensitivity is associated with allergic eosinophilic rhinitis at 4 years of age. Ann Allergy Asthma Immunol. 2015 Mar;114(3):193-198.e4. doi: 10.1016/j.anai.2014.12.008.

Biagini Myers JM, Simmons JM, Kercsmar CM, Martin LJ, Pilipenko VV, Austin SR, Lindsey MA, Amalfitano KM, Guilbert TW, McCoy KS, Forbis SG, McBride JT, Ross KR, Vauthy PA, Khurana Hershey GK. Heterogeneity in Asthma Care in a Statewide Collaborative: the Ohio Pediatric Asthma Repository. Pediatrics. 2015 Jan 19. pii: peds.2014-2230. [Epub ahead of print]


Codispoti CD, LeMasters GK, Levin L, Reponen T, Ryan PH, Biagini Myers JM, Villareal M, Burkle J, Evans S, Lockey JE, Khurana Hershey GK, Bernstein DI.  Traffic pollution is associated with early childhood aeroallergen sensitization. Ann Allergy Asthma Immunol. 2014 Dec 10. pii: S1081-1206(14)00756-X. doi: 10.1016/j.anai.2014.10.020. [Epub ahead of print].


Amin P, Levin L, Epstein T, Ryan P, LeMasters G, Khurana Hershey G, Reponen T, Villareal M, Lockey J, Bernstein DI. Optimum predictors of childhood asthma: persistent wheeze or the asthma predictive index? J Allergy Clin Immunol Pract. 2014 Nov-Dec;2(6):709-715.e2. doi: 10.1016/j.jaip.2014.08.009. Epub 2014 Nov 6. 

LeMasters G, Levin L, Bernstein DI, Lockey SD 4th, Lockey JE, Burkle J, Khurana Hershey GK , Brunst K, Ryan PH. Secondhand smoke and traffic exhaust confer opposing risks for asthma in normal and overweight children.Obesity (Silver Spring).  2014 Nov 19. doi: 10.1002/oby.20941. [Epub ahead of print]

Ji H, Zhang X, Oh S, Mayhew CN, Ulm A, Somineni HK, Ericksen M, Wells JM, Khurana Hershey GKDynamic transcriptional and epigenomic reprogramming from pediatric nasal epithelial cells to induced pluripotent stem cellsJ Allergy Clin Immunol. 2014 Oct 14. pii: S0091-6749(14)01262-7. doi: 10.1016/j.jaci.2014.08.038. [Epub ahead of print] 

Cheng G, Smith AM, Levin L, Epstein T, Ryan PH, LeMasters GK, Khurana Hershey GK , Reponen T, Villareal M, Lockey J, Bernstein DI. Duration of Daycare Attendance During Infancy Predicts Asthma at Age Seven: The Cincinnati Childhood Allergy and Air Pollution Study (CCAAPS). Clin Exp Allergy . 2014 Sep 2. doi: 10.1111/cea.12397. [Epub ahead of print]

LeMasters GK, Khurana Hershey GK , Sivaprasad U, Martin LJ, Pilipenko V, Ericksen MB, Burkle JW, Lindsey MA, Bernstein DI, Lockey JE, Gareri J, Lubetsky A, Koren G, Biagini Myers JM. N-acetyltransferase 1 polymorphism increases cotinine levels in Caucasian children exposed to secondhand smoke: the CCAAPS birth cohort.  Pharmacogenomics J . 2014 Aug 26. doi: 10.1038/tpj.2014.44. [Epub ahead of print]

Sivprasad U, Kinker KG, Ericksen MB, Lindsey M, Gibson AM, Bass SA, Hershey NS, Deng J, Medvedovic M, Khurana Hershey GK . SERPINB3/B4 Contributes to Early Inflammation and Barrier Dysfunction in an Experimental Murine Model of Atopic Dermatitis. J Invest Dermatal . 2014 Aug 11. Doi: 10.1038/jid.2014.353. [Epub ahead of print] 

Biagini Myers JM, Martin LJ, Butsch Kovacic M, Mersha TB, He H, Pilipenko V, Lindsey MA, Ericksen MB, Bernstein DI, LeMasters GK, Lockey JE, Khurana Hershey GK . Epistasis between serine protease inhibitor Kazal-type 5 (SPINK5) and thymic stromal lymphopoietin (TSLP) genes contributes to childhood asthma. J Allergy Clin Immunol .  2014 May 13. pii: S0091-6749(14)00520-X. doi: 10.1016/j.jaci.2014.03.037. [Epub ahead of print]

Brandt EB, Ryan PH, Khurana Hershey GK . ReplyJ Allergy Clin Immunol. 2014 Mar 15. pii: S0091-6749(14)00194-8. doi: 10.1016/j.jaci.2013.12.1097. [Epub ahead of print]

Kinker KG, Gibson AM, Bass SA, Day BP, Deng, J, Medvedovic M, Figueroa JA, Gurjit K. Khurana Hershey , Chen W. Overexpression of dimethylarginine dimethylaminohydrolase 1 attenuates airway inflammation in a mouse model of asthmaPloS One. 2014 Jan10;9 (1):e85148. doi: 10.1371/journal.pone.0085148.eCollection 2014.

Zhonghua Zhang, Chang Xiao, Aaron M. Gibson, Stacey A. Bass, Gurjit K. Khurana Hershey . EGFR signaling blunts allergen-induced IL-6 production and Th17 responses in the skin and attenuates development and relapse of atopic dermatitis. J Immunol. Feb 2014.

Qin Wei, Youbao Sha, Abhisek Bhattacharya, Elmoataz Abdel Fattah, Diana Bonilla, Soma S. S. K. Jyothula, Lavannya Pandit, Gurjit Khurana Hershey , and N. Tony Eissa. Regulation of IL-4 Receptor Signaling by STUB1 in Lung Inflammation. Am J Respir Crit Care Med. 2014 Jan 1;189(1):16-29.

Robert A. Wood, Alkis Togias, Jeremy Wildfire, Cynthia M. Visness, Elizabeth Matsui, Rebecca Gruchalla, Gurjit Khurana Hershey, Andrew H. Liu, George T. O’Connor, Jacqueline A. Pongracic, Edward Zoratti, Frederic Little, Mark Granada, Suzanne Kennedy, Stephen R. Durham, Mohamed H. Shamji, and William W. Busse. Development of cockroach immunotherapy by the Inner-City Asthma Consortium. J Allergy Clin Immunol. Oct 31, 2013.

Thomas H. Acciani, Eric B. Brandt, Gurjit K Khurana Hershey, Timothy D. Le Cras. Diesel exhaust particle exposure increases severity of allergic asthma in young mice and children. Clin Exp Allergy 2013 Sep 24 doi:10.1111/cea.1200 [Epub ahead of print].

Eric B. Brandt, Melinda Butsch Kovacic, Gerald B. Lee, Jocelyn M. Biagini Myers, Mark Lindsey, Aaron M. Gibson, Thomas Acciani, Timothy D. Le Cras, Alison L. Budelsky, and Gurjit K. Khurana Hershey. Diesel exhaust particle induction of IL17A contributes to severe asthmaJ Allergy and Clin Immunol.  Sep. 2013 [Epub ahead of print].

Eric Brandt, Aaron M. Gibson, Stacey Bass, Mark Lindsey, and Gurjit K. Khurana Hershey. Exacerbation of allergen-induced eczema in TLR4- and TRIF-deficient mice. J Immunol. 2013 Oct 1; 191(7):3519-25.

Weiguo Chen, Umasundari Sivaprasad, Aaron M. Gibson, Mark B. Ericksen, Christie M. Cunningham, Stacey A. Bass, Kayla G. Kinker, Fred D. Finkelman, Marsha Wills-Karp, and Gurjit K. Khurana Hershey. IL-13 receptor alpha 2 contributes to development of experimental allergic asthma. J Allergy Clin Immunol. 2013 Oct;132(4):951-958.

Gerald B. Lee, Eric B. Brandt, Chang Xiao, Aaron Gibson, Timothy D. Le Cras, Lou Ann S. Brown, Anne M. Fitzpatrick, and Gurjit Khurana Hershey. Diesel exhaust particles induce cysteine oxidation and S-Glutathionylation in house dust mite induced murine asthma. PLoS One 2013;8(3):e60632 Epub 2013 Mar 29.

Lili Ding, Tilahun Abebe, Joseph Beyene, Russell A. Wilke, Arnon Goldberg, Jessica G.  Woo, Carolyn Kercsmar, Greg Grabowski, Hua He, Sushil Amirisetty, Lisa J Martin, Marc E. Rothenberg, Marepalli Rao, Gurjit K Khurana Hershey, Ranajit Chakraborty, and Tesfaye M Baye. Rank based genome wide analysis reveals association of ryanodine receptor-2 gene variants with childhood asthma among human populations. Hum Genom. 2013 Jul 5;7(1):16.

Elisabet Johansson, Tiina Reponen, Stephen Vesper, Linda Levin, James Lockey, Patrick Ryan, David I. Bernstein, Manuel Villareal, Gurjit Khurana Hershey, Chris Schaeffer, and Grace LeMasters. Microbial content of household dust associated with exhaled NO in asthmatic children. Environ Int. 2013 Sep 24;59:141-147.

Nicholas C. Newman, Patrick H. Ryan, Grace LeMasters, Linda Levin, David Bernstein, Gurjit K. Khurana Hershey, James E. Lockey, Manuel Villareal, Tiina Reponen, Sergey Grinshpun, Heidi Sucharew, and Kim N. Dietrich. Traffic related air pollution exposure in the first year of life and behavioral scores at age seven.  Environ Health Perspect. 2013 Jun;121(6):731-6 2013 Epub 2013 Apr 5.

Rachael Mintz-Cole, Eric B. Brandt, Stacey A. Bass, Aaron M. Gibson, Tiina Reponen, and Gurjit K. Khurana Hershey. Surface availability of beta-glucans is critical determinant of host immune response to C. cladosporioides. J Allergy Clin Immunol. 2013 Jul;132(1):159-69.

Kelly J. Brunst, Yuet-Kim Leung, Patrick Ryan, Gurjit K. Khurana Hershey, Linda Levin, Hong Ji, Grace K. LeMasters, and Shuk-Mei Ho. Forkhead Box Protein (FOX3P) hypermethylation is associated with diesel exhaust exposure and risk for childhood asthma. J Allergy Clin Immunol. 2013 Feb;131(2):592-594.e3. Epub 2012 Dec 20.  

Elizabeth M. Mushaben, Eric B. Brandt, Gurjit K. Khurana Hershey, Timothy D. Le Cras. Differential effects of rapamycin and dexamethasone in mouse models of established allergic asthma. PLoS ONE 2012 8(1):e54426.

Rachael Mintz-Cole, Aaron M. Gibson, Stacey A. Bass, Alison L. Budelsky, Tiina Reponen, and Gurjit K. Khurana Hershey. Dectin-1 and IL-17A suppress murine asthma induced by Aspergillus versicolor but not Cladosporium cladosporioides due to differences in beta-glucan surface exposure. J Immunol. 2012 Oct 1;189(7):3609-17. Epub 2012 Sep 7.

Tiina Reponen, James Lockey, David I. Bernstein, Stephen J. Vesper, Linda Levin, Gurjit K. Khurana Hershey, Shu Zheng, Patrick Ryan, Sergey Grinspun, Manuel Villareal, and Grace LeMasters. Infant origins of childhood asthma associated with specific molds. J Allergy Clin Immunol. 2012 Sep;130(3):639-644.e5. epub 2012 Jul 11. 

Heijn Kim, Linda Levin, Grace K. LeMasters, Manuel Villareal, Sherry Evans, James E. Lockey, Gurjit K. Khurana Hershey, and David I. Bernstein. Validating childhood symptoms with physician-diagnosed allergic rhinitis. Ann Allergy Asthma Immunol. 2012 Apr; 108(4)228-31. Epub 2012 Feb 28.

Melinda Butsch Kovacic, Jocelyn M. Biagini Myers, Mark Lindsey, Tia Patterson, Sharon Sauter, Mark. B. Ericksen, Patrick Ryan, Amal Assa’ad, Michelle Lierl, Thomas Fischer, Carolyn Kercsmar, Karen McDowell, Anne W. Lucky, Anita P. Sheth, Andrew D. Hershey, Richard M. Ruddy, Marc E. Rothenberg, and Gurjit K. Khurana Hershey. The Greater Cincinnati Pediatric Clinic Repository (GCPCR):  A novel framework for childhood asthma and allergy research. Ped Aller Immunol Pulmonol. 2012 Jun; 25(2):104-113

Tesfaye M. Baye, Sushil Amirisetty, Gurjit K. Khurana HersheyAncestrySNPminer:  A bioinformatics tool to retrieve and develop ancestry informative SNP panels. Genomics 2012 Jul; 100(1):57-63. Epub 2012 May 11.

Jocelyn M Biagini Myers, Gurjit K Khurana Hershey, Prodipto Pal, Ranjan Deka, Jeffrey Burkle, Linda S. Levin, David I. Bernstein, Manuel Villareal, James E. Lockey, Tiina Reponen, Joey Gareri, Angelika Lubetsky, Gideon Koren, and Grace K. LeMasters. Asking the right questions to ascertain early childhood secondhand smoke exposures?  J Pediatr. 2012 Jun; 160(6):1050-1. Epub 2012 Apr 10.

Lisa J. Martin, Jayanta Gupta, Soma SSK Jyothula, Melinda Butsch Kovacic, Jocelyn M. Biagini Myers, Tia L. Patterson, Mark B. Ericksen, Hua He, Aaron M. Gibson, Tesfaye M. Baye, Anna M. Tsoras, Youbao Sha, N. Tony Eissa, and Gurjit K. Khurana HersheyFunctional variant in the autophagy-related 5 gene promotor is associated with childhood asthma. PLoS One 2012; 7(4):e33454. Epub 2012 Apr 20.

Kelly J. Brunst, Patrick H. Ryan, James E. Lockey, David I. Bernstein, Roy T. McKay, Gurjit K. Khurana Hershey, Manuel Villareal, Jocelyn M. Biagini Myers, Linda Levin, Jeff Burkle, Sherry Evans, and Grace K. LeMasters. Unraveling the relationship between aeroallergen sensitization, gender, second-hand smoke exposure and impaired lung function. Pediatr Allergy Immunol.2012 Mar 22. doi: 10.1111/j.1399-3038.2012.01292.x. [Epub ahead of print].

Elizabeth Mushaben, Gurjit K. Khurana Hershey, Mike W. Pauciulo, William C. Nichols, and Timothy D. Le Cras. Chronic allergic inflammation causes vascular remodeling and pulmonary hypertension in BMPR2 hypomorph and wild-type mice. PLoS One 2012; 7(3):  e32468. Doi:10.1371/journal.pone.0032468.

Marsha Wills-Karp, Reena Rani, Krista Dienger, Ian Lewkowich, James G. Fox, Lauren Lews, Fred D. Finkelman, Dirk E. Smith, Paul J. Bryce, Evelyn A. Curt-Jones, Timothy C. Wang, Umasundari Sivaprasad, Gurjit K. Khurana Hershey, and De’Broski R. Herbert. Trefoil factor 2 rapidly induces Interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infectionJ. Exp. Med. 2012 Mar 12;209(3):607-22. Epub 2012 Feb 13.

Tolly G. Epstein, Grace K. LeMasters, David I. Bernstein, Mark Ericksen, Patrick H. Ryan, Jocelyn Biagini Myers, Melinda Butsch-Kovacic, Mark Lindsey,Tiina Reponen, Manual Villareal, James E. Lockey, and Gurjit K. Khurana Hershey. Genetic variation in small proline rich protein 2B is a strong predictor for asthma among children with eczema. Ann Allergy Asthma Immunol. 2012 Mar; 108(3):145-150.e4.

Hong Ji and Gurjit K. Khurana Hershey. Genetic and epigenetic influence on the response to environmental particulate matter. J Allergy Clin Immunol. 2012 Jan; 129(1):33-41.   

Lili Ding, Howard Wiener, Tilahun Abebe, Mekbib Altaye, Rodney CP Go, Carolyn Kercsmar, Greg Grabowski, Lisa Martin, Gurjit K. Khurana Hershey, Ranajit Chakorborty, and Tesfaye Mersha. Comparison of measures of marker informativeness for ancestry and admixture mapping. BMC Genomics 2011 Dec 20; 12(1):622.

Elizabeth Mushaben, Elizabeth Kramer, Eric Brandt, Gurjit Khurana Hershey, and Timothy D. Le Cras. Rapamycin attenuates airway hyperactivity, IgE, T cells and mediators of allergic asthma. J Immunol. 2011 Dec 1; 187(11):5756-63. Epub 2011 Oct 21.

Burcin Uygungil, Kimberly Risma, Gurjit K. Khurana Hershey, and Amal H. Assa’ad. Immunodeficiency?  A problem with the faucet or the drain. Ann Allergy Asthma Immunol. 2011 Dec; 107(6):547-9.

Melinda Butsch Kovacic, Jocelyn Biagini Myers, Ning Wang, Lisa Martin, Mark Lindsey, Mark Erickson, Hua He, Tia Patterson, Tesfaye Mersha, Jayanta Gupta, Umasundari Sivaprasad, Aaron Gibson, Anna Tsoras, Donglei Hu, Celeste Eng, Rocio Chapela, Jose Rodriguez-Santa, William Rodriguez-Cintron, Pedro Avila, Kenneth Beckman, Max Seibold, Chris Gignoux, Salma Musaad, Weiguo Chen, Esteban Burchard, and Gurjit K. Khurana Hershey. A novel unbiased approach identifies the KIF3A gene as an epithelial biomarker of childhood asthma. PLoS One 2011; 6(8):e23714. Epub 2011 Aug 30. 

Elizabeth L. Kramer, William D. Hardie, Elizabeth M. Mushaben, Thomas H. Acciani, Patricia A. Pastura, Thomas R. Korfhagen, Gurjit K. Khurana Hershey, and Timothy D. Le Cras. Rapamycin decreases airway remodeling and hyperactivity in a transgenic model of noninflammatory lung disease. J Appl Physiol. 2011; 111:1760-1767. Epub 2011 Sep 8.

Tiina Reponen, Stephen Vesper, Linda Levin, Elisabet Johansson, Patrick Ryan, Jeffery Burkle, Sergey Grinspun, Shu Zheng, Gurjit K. Khurana Hershey, David I. Bernstein, James Lockey, and Grace LeMasters. High environmental relative moldiness index during infancy as a predictor of age seven asthma. Ann Allergy Asthma Immunol. 2011 Aug; 107(2):120-6. Epub 2011 May 28.

Kathy T. Schroer, Aaron M. Gibson, Umasundari Sivaprasad, Stacey A. Bass, Mark B. Ericksen, Marsha Wills-Karp, Tim Le Cras, Anne M. Fitzpatrick, Lou Ann S. Brown,  Keith F. Stringer, and Gurjit K. Khurana Hershey. Down-regulation of glutathione S-transferase pi in asthma contributes to enhanced oxidative stress. J Allergy Clin Immunol. 2011 Sep; 128(3):539-48. Epub 2011 May 13.

David I. Bernstein, Grace Kissling, and Gurjit K. Khurana Hershey, Andre` Carter, Berran Yucesoy, Denyse Gautrin, Joaquin Sastre, Louis-Philippe Boulet, Jean-Luc Malo, Santiago Quirce, Susan Tarlo, Victor Johnson, Stacy Langmeyer, Michael Luster, Zana Lummus. Hexamethylene Diisocyanate asthma is associated with genetic polymorphisms of CD14, IL-13, and IL-4Ra. J Allergy Clin Immunol. 2011 Aug; 128(2):418-20. Epub 2011 Apr 13.

Sandra Cortina, Dennis Drotar, Mark Ericksen, Mark Lindsey, Tia L. Patterson, Jocelyn M. Biagini Myers, Melinda Butsch Kovacic, and Gurjit K. Khurana Hershey. Genomic biomarkers of health-related quality of life in pediatric asthma. J Pediatr. 2011 Jul; 159(1):21-26.e1. Epub 2011 Feb 15.2011 Feb 14. [Epub ahead of print]

Dawn C. Newcomb, Madison G. Boswell, Weisong Zhou, Matthew M. Huckabee, Kasia Goleniewska, Carla M. Sevin, Gurjit K. Khurana Hershey, Jay K. Kolls, and R. Stokes Peebles. Human Th17 cells express a functional IL-13 receptor and IL-13 attenuates IL-17A production. J Allergy Clin Immunol. 2011 Apr; 127(4):1006-1013.e4. Epub 2011 Jan 13.

Tesfaye M. Baye, Melinda Butsch Kovacic, Jocelyn M. Biagini Myers, Lisa J. Martin, Mark Lindsey, Tia L. Patterson, Hua He, Mark B. Ericksen, Jayanta Gupta, Anna M. Tsoras, Andrew Lindsey, Marc E. Rothenberg, Marsha Wills-Karp, N. Tony Eissa, Larry Borish, and Gurjit K. Khurana Hershey. Differences in candidate gene association between European ancestry and African American asthmatic children. PLoS One 2011 Feb 28; 6(2):e16522.

Timothy Le Cras, Thomas Acciani, Elizabeth Mushaben, Elizabeth Kramer, Patricia Pastura, William Hardie, Thomas Korfhagen, Umasundari Sivaprasad, Mark Ericksen, Aaron Gibson, Michael Holtzman, Jeffrey Whitsett, and Gurjit Khurana Hershey. Epithelial EGF receptor signaling mediates airway hyperreactivity and remodeling in a mouse of chronic asthma. Am J Physiol Lung Cell Mol Physiol. 2011 Mar; 300(3):L414-21. Epub 2010 Dec 17.

Umasundari Sivaprasad, David J. Askew, Mark B. Ericksen, Aaron M. Gibson, Matthew T. Stier, Stacey A. Bass, Michael O. Daines, Jamila Chakir, Keith F. Stringer, Susan E. Wert, Jeffrey A. Whitsett, Timothy D. Le Cras, Marsha Wills-Karp, Gary A. Silverman, and Gurjit K. Khurana HersheyA non-redundant role for Serpinb3a in the induction of mucous production in asthma. J Allergy Clin Immunol. 2011 Jan; 127(1):254-61, 261.e1-6. Epub 2010 Dec 3. Editor’s Pick.

Umasundari Sivaprasad, Manoj R. Warrier, Aaron M. Gibson, Weiguo Chen, Yasuhiro Tabata, Marc E. Rothenberg, and Gurjit K. Khurana Hershey. IL-13 receptor Alpha2 has a protective role in a mouse model of cutaneous inflammation. J Immunol. 2010 Dec 1; 185(11):6802-8 Epub 2010 Oct 22.

Tolly Epstein, David I. Bernstein, Linda Levin, Gurjit K. Khurana Hershey, Patrick H. Ryan, Tiina Reponen, Manuel Villareal, Heidi Sucharew, Enis Alshaikh, Jeff Burkle, James E. Lockey, and Grace LeMasters. Opposing effects of cat and dog ownership and allergic sensitization on eczema in an atopic birth cohort. J Pediatr. 2011 Feb; 158(2):265-271.e5 Epub 2010 Sep 29.

Tesfaye M. Baye, Lisa J. Martin, and Gurjit K. Khurana Hershey. Application of genetic/genomic approaches to allergic disorders. J Allergy Clin Immunol. 2010 Sep;126(3):425-36;quiz 437-8. Epub 2010 Jul 16.

Joseph D. Sherrill, Pei-Song Gao, Emily M Stucke, Carine Blanchard, Margaret H. Collins, Phil E. Putnam, James P. Franciosi, Johnathan P. Kushner, J. Pablo Abonia, Amal H. Assa’ad, Melinda Butsch Kovacic, Jocelyn M Biagini Myers, Bruce S. Bochner, Hua He, Gurjit K. Khurana Hershey, Lisa J. Martin, and Marc E. Rothenberg.  Variants of thymic stromal lymphopoietin and its receptor associate with eosinophilic esophagitis. Journal of Allergy Clin Immunol. 2010 Jul; 126(1):160-5.e3.

Jocelyn Biagini Myers and Gurjit K. Khurana HersheyEczema in early life: Lessons learned from birth cohort studies. J Pediatr. 2010 Nov;157(5):704-14. Epub 2010 Aug 24.

Christopher D. Codispoti, Linda Levin, Grace K. LeMasters, Patrick Ryan, Tiina Reponen, Manuel Villareal, James Lockey, Gurjit K. Khurana Hershey, and David I. Bernstein. Breastfeeding allergen sensitization and the indoor environmental exposure during infancy to determine allergic rhinitis at age 3:  The CCAAPS birth cohort. J Allergy and Clin Immunol. 2010 May;125(5):1054-1060.e1. Epub 2010 Apr 14.

Heidi Sucharew, Paul Succop, Patrick Ryan, David Bernstein, Gurjit K. Khurana Hershey, James Lockey, Manuel Villareal, Tiina Reponen, Sergey Grinshpun, and Grace LeMasters. Exposure to traffic exhaust and night cough during early childhood: the CCAAPS Cohort. Pediatr Allergy Immunol. 2010 Mar;21(2 Pt 1):253-9. Epub 2009 Oct 12.

Fred D. Finkelman, Simon P. Hogan, Gurjit K. Khurana Hershey, Marc E. Rothenberg, and Marsha Wills-Karp. Importance of cytokines in murine allergic airway disease and human asthma. J Immunol. 2010 Feb 15;184(4):1663-74 Review.

Weiguo Chen, Umasundari Sivaprasad, Yasuhiro Tabata, Aaron M. Gibson, Matthew T. Stier, Fred Finkelman, and Gurjit K. Khurana HersheyIL-13 Receptor alpha 2 membrane and soluble isoforms differ in human and mouse. J Immunol. 2009 Dec 15;183(12):7870-6.

Jocelyn M. Biagini Myers, Ning Wang, Grace LeMasters, David I. Bernstein, Tolly Epstein, Mark Lindsey, Mark Ericksen, Ranajit Chakraborty, Patrick Ryan, Manuel Villareal, Jeff Burkle, James Lockey, Tiina Reponen, and Gurjit K. Khurana Hershey. Genetic and environmental risk factors in the development of childhood eczema - Results from the CCAAPS Birth Cohort. J Invest Dermatol. 2010 Feb;130(2):430-7. Epub 2009 Sep 17.

Raffi Tachdjian, Paul J. Bryce, Frank Blaeser, Brian D. O’Connor, Danuta Rzymkiewicz, Benjamin Caplan, Michael J. Holtzman, Gurjit K. Khurana Hershey, Holger Garn, Hani Harb, Harald Renz, Hans C. Oettgen, and Talal A. Chatila. Pathogenicity of a disease-associated human IL-4 receptor allele in experimental asthma. J Exp Med. 2009 Sep 28;206(10):2191-204. Epub 2009 Sep 21.

Patrick Ryan, David I. Bernstein, Tiina Reponen, Linda Levin, Sergey Grinshpun, Manuel Villareal, James Lockey, Gurjit K. Khurana Hershey, Jeffrey Burkle, and Grace LeMasters. Exposure to traffic related particles and endotoxin during infancy is associated with wheezing at age three. Am J Respir Crit Care Med. 2009 Dec 1;180(11):1037-8.

Leah C. Kottyan, Ann R. Collier, KH Cao, Kathryn A. Niese, M Hedgebeth, CG Radu, ON Witte, Gurjit K. Khurana Hershey, Marc E. Rothenberg, and Nives Zimmermann. Eosinophil viability is increased by acidic pH in a cAMP and GPR65-dependent manner.  Blood. 2009 Sep 24; 114(13):2774-82. Epub 2009 Jul 29.

Elizabeth L. Kramer, Elizabeth M. Mushaben, Patricia A. Pastura, Thomas H. Acciani, Gail H. Deutsch, Gurjit K. Khurana Hershey, Thomas R. Korfhagen, William D. Hardie, Jeffrey A. Whitsett, and Timothy D. Le Cras.  Egr-1 suppresses EGFR-mediated airway hyperresponsiveness and lung remodeling in mice. Am J Resp Cell Mol Biol.  2009 Oct;41(4):415-25. Epub 2009 Feb 2.

Salma M.A. Musaad, Tia Patterson, Mark Ericksen, Mark Lindsey, Kim Dietrich, Paul Succop, and Gurjit K. Khurana HersheyComparison of anthropometric measures of obesity in childhood asthma. J Allergy Clin Immunol. 2009 Jun;123(6):1321-7.e12

Dawn C. Newcomb, Weisong Zhou, Martin M. Moore, Kasia Goleniewska, Gurjit K. Khurana Hershey, Jay K. Kolls, and R. Stokes Peebles, Jr. A functional IL-13 receptor is expressed on polarized murine CD4+ Th17 cells and IL-13 signaling negatively regulates Th17 cytokine production. J Immunol. 2009 May1;182(9):5317-21.

Ning Wang, Gurjit K. Khurana Hershey. Pediatric Pharmacogenomics and Gene Therapy In:  Handbook of Genomics and the Family, New York:  Springer Medical Publishing Division, 2009.   

Yulia Iossifova, Tiina Reponen, Patrick Ryan, Linda Levin, David Bernstein, James Lockey, Gurjit K. Khurana Hershey, Manuel Villareal, and Grace LeMasters. Mold exposure during Infancy as a strong predictor of potential asthma developmentAnn Allergy Asthma Immunol. 109:131-37, 2009.

Kelly Allred Metz, Gurjit K. Khurana Hershey, Michelle B. Lierl, Luqman Seidu, and Amal H. Assa’ad.  Successful administration of cytarabine in a 16 month old with AML and cytarabine syndrome. Ann Allergy Asthma Immunol. 102(2)173-4, Feb 2009.

Kathy T. Schroer, Jocelyn M. Biagini, Patrick H. Ryan, Grace K. LeMasters, David I. Bernstein, Manuel Villareal, James E. Lockey, Tiina Reponen, Sergey Grinshpun, and Gurjit K. Khurana Hershey. Associations between multiple environmental exposures and glutathione S-transferase P1 on persistent wheezing in a birth cohort. J Pediatr. Mar;154(3)401-8, 2009.

Gurjit K. Khurana Hershey.  Asthma. In: Rudolph AM, et al. (editor) Rudolph’s Pediatrics, 22nd Edition, New York:  McGraw-Hill Medical Publishing Division, 2008.

Weiguo Chen, Yasuhiro Tabata, Aaron M. Gibson, Michael O. Daines, Manoj R. Warrier, Marsha Wills-Karp, and Gurjit K. Khurana Hershey. Matrix metalloproteinase-8 contributes to solubilization of interleukin-13 receptor alpha-2 in vivo.  J Allergy Clin Immunol. 2008Sep;122(3):625-32. Epub 2008 Aug 9.

Eric B. Brandt, Melissa K. Mingler, Michelle Stevenson, Ning Wang, Gurjit K. Khurana Hershey, Jeffrey A. Whitsett, and Marc E. Rothenberg. Surfactant protein-D alters allergic lung responses in mice and manJ Allergy Clin Immunol. 121:1140-7, 2008.

Jayanta Gupta, Emilie Grube, Mark Ericksen, Michelle Stevenson, Anne W. Lucky, Anita Sheth, Amal Assa’ad, and Gurjit K. Khurana Hershey. Intrinsically defective skin barrier function in children with atopic dermatitis correlates with disease severity. J Allergy Clin Immunol.  121(3)725-30, 2008.

Manoj Warrier, Gurjit K. Khurana Hershey. Asthma genetics:  personalizing medicine. J Asthma. 45:257-264, 2008.

Marat Khodoun, Christina Lewis, Jun-Qi Yang, Tatyana Orekov, Crystal Potter, Thomas Wynn, Margaret Mentink-Kane, Gurjit K. Khurana Hershey, Marsha Wills-Karp, and Fred Finkelman. Differences in expression, affinity and function of soluble(s) IL-4Ra and sIL-13a2 suggest opposite effects on allergic responses. J Immunol. 179:6429-6438, Nov 2007. Correction 180:664, Jan 2008.

Andrew M. Smith, David I. Bernstein, Grace K. LeMasters, Nanette L. Huey, Mark Ericksen, Manuel Villareal, James Lockey, and Gurjit K. Khurana Hershey. Environmental tobacco smoke and IL-4 polymorphism (C-589T) gene: environment interaction increases risk of wheezing in African-American infants: the Cincinnati Childhood Allergy and Air Pollution Study (CCAAPS)J Pediatr. 152:709-715, 2008.

Yulia Iossifova, Tiina Reponen, Michael Daines, C. Crawford, and Gurjit K Khurana HersheyComparison of two analytical methods for detecting (1-3)-b-D-glucan in pure fungal cultures and in home dust samples. The Open Allergy Journal.  1:26-34, 2008. 

Michelle D. Stevenson, Stacey Sellins, Kathy Schroer, Jayanta Gupta, Emilie Grube, and Gurjit K. Khurana Hershey. Aeroallergen sensitization in healthy children: racial and socioeconomic correlates. J Pediatr. 151:187-91, 2007.  PMCID:  PMC2013934.

Yulia Iossifova, Tiina Reponen, David Bernstein, Linda Levin, Harpinder Kalra, Paloma Campo, Manuel Villareal, James Lockey, Gurjit K. Khurana Hershey, and Grace Lemasters. House dust (1-3)-b-D-glucan and wheezing in infants. Allergy. 62: 504-513, 2007.

Yasuhiro Tabata, Gurjit K. Khurana HersheyIL-13 receptor isoforms: breaking through the complexityCurr Allergy Asthma Rep. 7:338-345, 2007.

Kwon-Sik Park, Thomas R. Korfhagen, Michael D. Bruno, Joseph A. Kitzmiller, Huajing Wan, Susan E. Wert, Gurjit K. Khurana Hershey, Gang Chen, and Jeffrey A. Whitsett. Spdef regulates goblet cell hyperplasia in the airway epithelium. J Clin Invest. 117(4): 978-988, 2007.  PMCID:  PMC1810569.

Weiguo Chen, Gurjit K. Khurana Hershey. Signal transducer and activator of transcription signals in allergic disease. J Allergy and Clin Immunol. 119; 529-41, 2007.

Patrick H. Ryan, Grace K. LeMasters, Pratim Biswas, Linda Levin, Shaohua Hu, Mark Lindsey, David I. Bernstein, James Lockey, Manuel Villareal, Gurjit K. Khurana Hershey, Sergey A. Grinshpun. A comparison proximity and land use regression traffic exposure models and wheezing in infants. Environ Health Perspect. 115:278-284, 2007.  PMCID:  PMC1817699.

Michael O. Daines, Weiguo Chen, Yasuhiro Tabata, Bradley A. Walker, Aaron M. Gibson, J. Alexander Masino, Manoj R. Warrier, Saswata Basu, Cori Daines, Sally E. Wenzel, and Gurjit K. Khurana Hershey.  Allergen-dependent solubilization of interleukin-13 receptor alpha-2 reveals a novel mechanism to regulate allergy. J Allergy and Clin Immunol. 119; 375-83, 2007.

Stephen J. Vesper, Craig McKinstry, Richard A. Haugland, Yulia Iossifova, Grace LeMasters, Linda Levin, Gurjit K. Khurana Hershey, Manuel Villareal, David I. Bernstein, James Lockey, and Tiina Reponen. Relative Moldiness Index© as predictor of childhood respiratory illness. J Of Expo Sci Environ Epidemiol. 17; 88-94, 2007.  PMCID:  PMC2233948.

Manoj Warrier, Gurjit K. Khurana Hershey.  Genetics of Asthma: Personalizing Health Care. U.S. Respiratory Care 2006

Paloma Campo, Harpinder K Kalra, Linda Levin, Tiina Reponen, Rolanda Olds, Zana L Lummus, Seung-Hyun Cho, Gurjit K. Khurana Hershey, James Lockey, Manuel Villareal, Shelley Stanforth, Grace LeMasters, David I Bernstein. Influence of dog ownership and high endotoxin on wheezing and atopy during infancy. J Allergy Clin Immunol. 118(6): 1271-8, 2006. PMCID: PMC2233938.

David I. Bernstein, Andre Cartier, Angela B. Heizer, Mark Wanner, Zana Lummus, Johanne Cote, Louis-Phillipe Boulet, Susan Tarlo, Ning Wang, Ranajit Chakraborty, and Gurjit K. Khurana Hershey. Diisocyanate asthma and gene-environment interactions with IL4-Receptor, CD-14 and IL-13 genes. Ann Allergy Asthma Immunol. 97 (6):800-6, 2006.

Yasuhiro Tabata,Weiguo Chen,Manoj R. Warrier, Aaron M. Gibson, Michael O. Daines, and Gurjit K. Khurana HersheyAllergy-driven alternative splicing of Interleukin-13 Receptor Alpha 2 yields distinct membrane and soluble forms. J Immunol. 177: 7905-7912, 2006.

Wei Zhong, Linda Levin, Tiina Reponen, Gurjit K. Khurana Hershey, Atin Adhikari, Grace Lemasters, and Rakesh Shukla.  Analysis of short-term influences of ambient aeroallergens on pediatric asthma hospital visits. Sci Total Environ.  370; 330-336, 2006.

Grace K. Lemasters, Kimberly Wilson, Linda Levin, Jocelyn Biagini, Patrick H. Ryan, James Lockey, MD; Sherry Stanforth, Stephanie Maier, RT; Jun Yang, Jeff Burkle, Manuel Villareal, Gurjit K. Khurana Hershey, David I Bernstein. High prevalence of aeroallergen sensitization among infants of atopic parents. J Pediatr. 149:505-11, 2006.  PMCID:  PMC2233934.

Hiroko Saito Akei, Eric B. Brandt, Anil Mishra, Richard T. Strait, Fred D. Finkleman, Manoj R. Warrier, Gurjit K. Khurana Hershey, Carine Blanchard, and Marc E. Rothenberg. Epicutaneous aeroallergen exposure induces systemic Th2 immunity that predisposes to allergic nasal responses. J. Allergy Clin Immunol. 118(1):62-69, 2006.

Jocelyn M. Biagini, Grace K. LeMasters, Patrick H. Ryan, Linda Levin, Tiina Reponen, David I. Bernstein, Manuel Villareal, Gurjit K. Khurana Hershey, Jeffrey Burkle and James Lockey. Environmental risk factors of rhinitis in early infancyPediatr Allergy Immunol. 17(4): 278-284, 2006.  PMCID:  PMC2233943

Michael O. Daines, Yasuhiro Tabata, Bradley A. Walker, Weiguo Chen, Manoj R. Warrier, Saswata Basu, and Gurjit K. Khurana Hershey. Level of expression of Interleukin-13 Receptor Alpha 2 impacts receptor distribution and IL-13 signaling. J Immunol. 176:7495-7501, 2006.

Jesus R. Guajardo, Michael O. Daines, Marsha Wills-Karp, Bruce J. Aronow, and Gurjit K. Khurana Hershey. Gene expression profiles in childhood asthma: differentiating between stable and acute asthma. J Allergy Clin Immunol. 116(3):710-711, 2005.

Jesus R. Guajardo, Kathleen W. Schleifer, Michael O. Daines, Richard M. Ruddy, Bruce J. Aronow, Marsha Wills-Karp, and Gurjit K. Khurana Hershey. Gene expression profiles in respiratory epithelium during stable and acute childhood asthma. J. Allergy Clin Immunol.  115(2): 243-251, 2005.

Weiguo Chen, Michael Daines, and Gurjit K. Khurana Hershey. Turning off STAT: the negative regulation of STAT signaling. J. Allergy Clin Immunol. 114:479-89, 2004.

Weiguo Chen, Mark Ericksen, Linda Levin, and Gurjit K. Khurana Hershey. Functional effect of the R110Q IL13 genetic variant alone and in combination with IL4RA genetic variants. J. Allergy Clin Immunol. 114:553-60, 2004.

Weiguo Chen, Michael O. Daines, and Gurjit K. Khurana Hershey. Methylation of Stat6 modulates Stat6 phosphorylation, nuclear translocation, and DNA binding activity.J Immunol. 172: 6744-6750, 2004.

Kathleen C. Barnes, Luis Caraballo, Melba Muñoz, April Zambelli-Weiner, Eva Ehrlich, Meher Burki, Silvia Jimenez, Rasika A. Mathias, Maria L. Stockton, Philip Deindl, Lynette Mendoza, Gurjit Khurana Hershey, Renate Nickel, and Marsha Wills-Karp. A novel promoter polymorphism in the gene encoding complement component 5 receptor 1 (C5R1) on chromosome 19q13.3 is not associated with asthma and atopy in three independent populations. Clin and Exp Allergy, 34:736-44, 2004.

Gurjit K. Khurana Hershey.  Is it all in our genes?  The mite-y truth. J Allergy Clin Immunol. 113:392-4, 2004.

Gurjit K. Khurana Hershey. IL-13 receptors and signaling. J Allergy Clin Immunol. 111:677-690, 2003.

Michael O. Daines, Ryan P. Andrews, Weiguo Chen, Shady A. El-Zayaty, and Gurjit K. Khurana HersheyDNA binding activity of cytoplasmic phosphorylated Stat6 is masked by an interaction with a detergent-sensitive factor. J Biol Chem.  278(33):30971-30974, 2003.

Jessica Woo, Amal Assa’ad, Angela Heizer, Jonathan A. Bernstein, and Gurjit K. Khurana Hershey. -159 CàT polymorphism of CD14 Is associated with non-atopic asthma and food allergy. J Allergy Clin Immunol.  112:438-444, 2003.

Nives Zimmermann, Gurjit Khurana-Hershey, Paul S. Foster, and Marc E. Rothenberg. Chemokines in asthma: co-operative interaction between chemokines and IL-13. J Allergy Clin Immunol. 111:227-42, 2003.

Marsha Wills-Karp, Gurjit K. Khurana Hershey. Immunological mechanisms of allergic disorders. In: Paul WE (editor): Fundamental Immunology, 4th Edition, New York: Raven Press, 2003.

Ryan P. Andrews, Mark B. Ericksen, Christie M. Cunningham, Michael O. Daines, Gurjit K. Khurana HersheyAnalysis of the life cycle of activated Stat6: continuous cycling of activated Stat6 is required for IL-4 signaling. J Biol Chem., 277 (39):36563-36569, 2002.

Kimberly A. Risma, Ning Wang,Ryan P. Andrews, Christie M. Cunningham, Mark B. Ericksen, Jonathan A. Bernstein, Ranajit Chakraborty, and Gurjit K. Khurana Hershey. V75R576 IL-4 receptor alpha is associated with allergic asthma and enhanced IL-4 receptor function. J Immunol. 169:1604-10, 2002.

Michael O. Daines and Gurjit K. Khurana HersheyA novel mechanism by which interferon-gamma can regulate IL-13 responses: evidence for intracellular stores of IL-13 receptor alpha 2 and their rapid mobilization by interferon-gamma. J Biol Chem. 277 (12) 10387-93, 2002.

Ryan P. Andrews, Lesley Burrell, Lillian Rosa-Rosa, Christie M. Cunningham, Jennifer L. Brzezinski, Jonathan A. Bernstein, and Gurjit K. Khurana HersheyAnalysis of the Ser786Pro Interleukin-4 receptor alpha allelic variant in allergic and non-allergic asthma and its functional consequences.  Clin Immunol. 100 (3): 298-304, 2001.

Erik D. White, Ryan P. Andrews, and Gurjit K. Khurana Hershey. Sulfhydryl-2 domain-containing tyrosine phosphatase-1 is not a negative regulator of IL-4 signaling in murine mast cells. J Leuk Biol., 69 (5): 825-830, 2001.

Michael O. Daines and Gurjit K. Khurana Hershey50 years ago in the Journal of Pediatrics - The effect of allergy management on growth and development of allergic children - Welsh JB. J Pediatr 1951;38:571-5. J Pediatr., 138: (6) 925, 2001.

Ryan P. Andrews, Lillian Rosa-Rosa, Michael Daines, Gurjit K. Khurana HersheyReconstitution of a functional human type II IL-4/IL-13 receptor in mouse B cells: demonstration of species-specificity.  J Immunol., 166:1716-1722, 2001.

Robert W. Wilmott, Gurjit K. Khurana Hershey, and James A. Stark. Current concepts on pulmonary host defense mechanisms in children. Curr Opin Pediatr. 2000, 12:187-193.

Lillian Rosa-Rosa, Nives Zimmerman, Jonathan A. Bernstein, Marc Rothenberg, and Gurjit K. Khurana Hershey. R576 Interleukin-4 receptor alpha allele correlates with asthma severity. J. Allergy and Clin Immunol. 104(5):1008-1014, 1999.

G.K. Khurana Hershey, M.F. Friedrich, L.A. Esswein, M.L. Thomas, and T.A. Chatila. The association of atopy with a gain-of-function mutation in the interleukin-4 receptor alpha chain. N Eng J Med. 337:1720, 1997.

G.K. Khurana Hershey, D.W. McCourt, and R.D. Schreiber. Ligand-induced phosphorylation of the human interferon-g receptor: Dependence on the presence of a functionally active receptor. J Biol Chem. 265:17868, 1990.

R. D. Schreiber, J. Calderon, G.K. Khurana Hershey, and P.W. Gray. The molecular and cell biology of the IFN-g receptor. In “Progress in Immunology,” Vol. VII. 7th International Congress of Immunology. Springer Verlag, Berlin, Germany. P. 641.1989.

G.K. Khurana Hershey and R.D. Schreiber. Biosynthetic analysis of the human interferon-gReceptor: identification of glycosylation intermediates. J Biol Chem. 264:11981, 1989.

Heterogeneity in asthma care in a statewide collaborative: The Ohio Pediatric Asthma Repository

Ohio maps.

Figures represent numbers of  OPAR recruitment and locations of OPAR study in Ohio. Created by Mark Lindsey- Application Specialist

Asthma heterogeneity causes difficulty in studying and treating the disease. In this study we build a comprehensive statewide repository linking questionnaire and medical record date with health outcomes to characterize the variability of clinical practices at Ohio children’s hospitals for the treatment of hospitalized asthma.


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