This research project focuses on candidate gene association, genome wide association analysis, and admixture mapping.
This project is a comprehensive expression profiling study to identify the genes / regulatory networks that impact asthma and atopic dermatitis phenotype. The goal of this project is to perform an in-depth AD murine model transcriptome analysis to identify genes whose expression is differentially and co-expressed with AD clinical outcomes.
Among immigrants from diverse ethnic backgrounds the duration of residence in developed countries is associated with increase in asthma risk. The goal of this project is to geographically isolated immigrant populations to dissect the role of environment / exposures in asthma pathogenesis.
The Ancestry SNPminer is a tool to develop ancestry informative markers (AIMs). Prioritizing informative markers to ancestry inference becomes critical. The goal of this project is to develop web-based bioinformatics tools specially designed to retrieve Ancestry Informative Markers (AIMs) from public databases and link these to informative markers to genes and ontological annotation classes.