2022; 6:01.. O-01: HYDROXYUREA REDUCES THE TRANSFUSION BURDEN IN CHILDREN WITH SICKLE CELL ANEMIA IN SUB-SAHARAN AFRICA: THE REACH EXPERIENCE. HemaSphere.
Active DNA damage response signaling initiates and maintains meiotic sex chromosome inactivation. Nature Communications. 2022; 13:7212..
Neonatal vascular anomalies manifesting as soft-tissue masses. Pediatric Radiology: roentgenology, nuclear medicine, ultrasonics, CT, MRI. 2022; 52:786-801..
Prognostic factors for patients with relapsed central nervous system nongerminomatous germ cell tumors. Pediatric Blood and Cancer. 2022; 69:e29365..
2022; 7:e602.. Testing an Automated Approach to Identify Variation in Outcomes among Children with Type 1 Diabetes across Multiple Sites. Pediatric Quality and Safety.
2022; 140:975-976.. A Circulating Microbial Metabolite Drives the Clonal Expansion of Pre-Leukemic Cells. Blood.
Angiopoietin-2-induced lymphatic endothelial cell migration drives lymphangiogenesis via the β1 integrin-RhoA-formin axis. Angiogenesis. 2022; 25:373-396..
GIST presenting as refractory iron-deficiency anaemia in paediatric patient. BMJ Case Reports. 2022; 15:e248365..
Meiotic sex chromosome inactivation and the XY body: a phase separation hypothesis. Cellular and Molecular Life Sciences. 2022; 79:18..
Preventing Cardiac Arrest in the Pediatric Cardiac Intensive Care Unit Through Multicenter Collaboration. JAMA Pediatrics. 2022; 176:1027-1036..
Aging of human hematopoietic stem cells is linked to changes in Cdc42 activity. Haematologica: the hematology journal. 2022; 107:393-402..
Human Spinal Organoid-on-a-Chip to Model Nociceptive Circuitry for Pain Therapeutics Discovery. Analytical Chemistry. 2022; 94:1365-1372..
Mitochondrial Fragmentation Triggers Ineffective Hematopoiesis in Myelodysplastic Syndromes. Cancer Discovery. 2022; 12:250-269..
2022; 140:5416-5417.. Individualized, PK-Guided Dosing of Hydroxyurea Is Not Associated with Increased Hematologic Toxicity Compared to Weight-Based Initial Dosing: Interim Results from the Hops Trial. Blood.
Granulocyte Transfusions in Patients with Chronic Granulomatous Disease Undergoing Hematopoietic Cell Transplantation or Gene Therapy. Journal of Clinical Immunology. 2022; 42:1026-1035..
Reduced-Intensity/Reduced-Toxicity Conditioning Approaches Are Tolerated in XIAP Deficiency but Patients Fare Poorly with Acute GVHD. Journal of Clinical Immunology. 2022; 42:36-45..
Pediatric Hydrocephalus in Northwest Tanzania: A Descriptive Cross-Sectional Study of Clinical Characteristics and Early Surgical Outcomes from the Bugando Medical Centre. World Neurosurgery. 2022; 161:e339-e346..
The ASTCT-NMDP ACCESS Initiative: A Collaboration to Address and Sustain Equal Outcomes for All across the Hematopoietic Cell Transplantation and Cellular Therapy Ecosystem. Transplantation and cellular therapy. 2022; 28:802-809..
Momelotinib is a highly potent inhibitor of FLT3-mutant AML. Blood Advances. 2022; 6:1186-1192..
Germline and Somatic Defects in DDX41 and its Impact on Myeloid Neoplasms. Current Hematologic Malignancy Reports. 2022; 17:113-120..
Single Site Experience of the use of Monoclonal Antibodies for the Treatment of COVID-19 in High-risk Pediatric and Young Adult Patients. The Pediatric Infectious Disease Journal. 2022; 41:985-988..
2022; 9.. 1119. Covid-19 Mab Use in High-Risk Pediatric Patients. Open Forum Infectious Diseases.
2022; 24:vii185-vii186.. NIMG-88. A TRANSFER LEARNING APPROACH FOR AUTOMATIC SEGMENTATION OF TUMOR SUB-COMPARTMENTS IN PEDIATRIC MEDULLOBLASTOMA USING MULTIPARAMETRIC MRI: PRELIMINARY FINDINGS. Neuro-Oncology.
Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia. Science Translational Medicine. 2022; 14:eabb7695..
Characteristics of children ≤36 months of age with DIPG: A report from the international DIPG registry. Neuro-Oncology. 2022; 24:2190-2199..
The new metabolic needs of hematopoietic stem cells. Current Opinion in Hematology. 2022; 29:188-193..
2022; 22:s160.. Poster: MPN-024 Hypereosinophilic Syndrome: A Catastrophic Pediatric Case. Clinical Lymphoma, Myeloma and Leukemia.
MPN-024 Hypereosinophilic Syndrome: A Catastrophic Pediatric Case. Clinical Lymphoma, Myeloma and Leukemia. 2022; 22 Suppl 2:S322..
2022; 121:s63-s64.. 106 GEMCITABINE, OXALIPLATIN, AND ANTI-CD20 THERAPY IS SAFE AND EFFECTIVE IN CHILDREN AND YOUNG ADULTS WITH NON-HODGKIN LYMPHOMA UNFIT FOR INTENSIVE THERAPY. Leukemia Research: clinical and laboratory studies.
IRAK1 and IRAK4 as emerging therapeutic targets in hematologic malignancies. Current Opinion in Hematology. 2022; 29:8-19..
2022; 140:2240-2241.. IRAK1 Contributes to IRAK4 Inhibitor Resistance Via Non-Canonical Signaling Mechanisms in MDS/AML. Blood.
A case of treatment-resistant membranous nephropathy associated with graft versus host disease successfully treated with daratumumab. Pediatric Transplantation. 2022; 26:e14263..
Quality of life in a large multinational haemophilia B cohort (The B-Natural study) - Unmet needs remain. Haemophilia. 2022; 28:453-461..
Clinical Characteristics and Outcomes of COVID-19 in Pediatric and Early Adolescent and Young Adult Hematopoietic Stem Cell Transplant Recipients: A Cohort Study. Transplantation and cellular therapy. 2022; 28:696.e1-696.e7..
Gain-of-function defects in toll-like receptor 8 shed light on the interface between immune system and bone marrow failure disorders. Frontiers in Immunology. 2022; 13:935321..
Forward: Welcome to the Special Issue on Vascular Anomalies. Pediatric Blood and Cancer. 2022; 69 Suppl 3:e29796..
NRASQ61R mutation in human endothelial cells causes vascular malformations. Angiogenesis. 2022; 25:331-342..
Urinary 11-dehydrothromboxane B2 aspirin efficacy testing is sensitive to perioperative inflammation in pediatric solid-organ transplant patients. Pediatric Blood and Cancer. 2022; 69:e29413..
Fertility preservation in children and young adults with cancer. Current Opinion in Pediatrics. 2022; 34:48-52..
Linking EORTC QLQ-C-30 and PedsQL/PEDQOL physical functioning scores in patients with osteosarcoma. European Journal of Cancer. 2022; 170:209-235..
Precision transfusion medicine: a new spin. Blood. 2022; 140:1661-1663..
Evaluation of amotosalen and UVA pathogen-reduced apheresis platelets after 7-day storage. Transfusion. 2022; 62:1619-1629..
Characterization and first-in-human clinical dose-escalation safety evaluation of a next-gen human freeze-dried plasma. Transfusion. 2022; 62:406-417..
Outcomes in Hematopoietic Stem Cell Transplantation for Congenital Amegakaryocytic Thrombocytopenia. Transplantation and cellular therapy. 2022; 28:101.e1-101.e6..
Hemostasis and tumor immunity. Research and Practice in Thrombosis and Haemostasis. 2022; 6:e12728..
2022; 208:121.12.. The role of the Thrombin/PAR axis in modulating CD8+ T cell anti-tumor immunity. Journal of immunology (Baltimore, Md. : 1950).
2022; 140:63-64.. U.S. Cohort Study of Previously Untreated Patients with Congenital Hemophilia (ATHN 8: PUPs Study): Inhibitor Development and Treatment Characteristics. Blood.
2022; 140:5593-5594.. Obesity and Race As Determinates of Plasma Von Willebrand and Factor VIII Levels. Blood.
Test-dose pharmacokinetics guided melphalan dose adjustment in reduced intensity conditioning allogeneic transplant for non-malignant disorders. British Journal of Clinical Pharmacology. 2022; 88:115-127..
Diurnal mood variation symptoms in major depressive disorder associated with evening chronotype: Evidence from a neuroimaging study. Journal of Affective Disorders. 2022; 298:151-159..
Quercetin ameliorates XIAP deficiency-associated hyperinflammation. Blood. 2022; 140:706-715..
Head and Neck Cancer Susceptibility and Metabolism in Fanconi Anemia. Cancers. 2022; 14:2040..
Rap1b-loss increases neutrophil lactate dehydrogenase activity to enhance neutrophil migration and acute inflammation in vivo. Frontiers in Immunology. 2022; 13:1061544..
2022; 140:5418-5419.. Return Visit Rates after an Emergency Department Treat-and-Release Visit for Children with Sickle Cell Pain Episodes. Blood.
2022; 94:s47-s48.. O086 FLASH Mechanisms Track (Oral Presentations) FLASH PROTON PENCIL BEAM SCANNING IRRADIATION USING A CLINICAL GANTRY DIMINISHES RADIATION INDUCED SKIN AND SOFT TISSUE TOXICITY IN MICE. Physica Medica: an international journal devoted to the applications of physics to medicine and biology.
Attenuated alpha-gamma coupling in emotional dual pathways with right-Amygdala predicting ineffective antidepressant response. CNS Neuroscience and Therapeutics. 2022; 28:401-410..
Disrupted fronto-parietal network and default-mode network gamma interactions distinguishing suicidal ideation and suicide attempt in depression. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2022; 113:110475..
Alpha-beta decoupling relevant to inhibition deficits leads to suicide attempt in major depressive disorder. Journal of Affective Disorders. 2022; 314:168-175..
2022; 6:1.. Commentary on McNeil et al. and Wolfe et al.
Primary cutaneous follicle center lymphoma of the medial canthus of the eye in an 11-year old. Pediatric Blood and Cancer. 2022; 69:e29630..
2022; 21:s86.. 147 Lung transplantation waitlist disparities for children with cystic fibrosis. Journal of Cystic Fibrosis.
2022; 114:s4.. FAST-01: Results of the First-in-Human Study of Proton FLASH Radiotherapy. International Journal of Radiation: Oncology - Biology - Physics.
High risk of relapsed disease in patients with NK/T-cell chronic active Epstein-Barr virus disease outside of Asia. Blood Advances. 2022; 6:452-459..
MEK inhibitors for neurofibromatosis type 1 manifestations: Clinical evidence and consensus. Neuro-Oncology. 2022; 24:1845-1856..
Olig2 defines a subset of neural stem cells that produce specific olfactory bulb interneuron subtypes in the subventricular zone of adult mice. Development (Cambridge). 2022; 149:dev200028..
Brain pharmacokinetics and metabolism of the AMP-activated protein kinase selective inhibitor SBI-0206965, an investigational agent for the treatment of glioblastoma. Investigational New Drugs. 2022; 40:944-952..
Phase I study of ribociclib and everolimus in children with newly diagnosed DIPG and high-grade glioma: A CONNECT pediatric neuro-oncology consortium report. Neuro-Oncology Advances. 2022; 4:vdac055..
International retrospective study of allogeneic hematopoietic cell transplantation for activated PI3K-delta syndrome. Journal of Allergy and Clinical Immunology. 2022; 149:410-421.e7..
Conserved and Distinct Functions of the Autism-Related Chromatin Remodeler CHD8 in Embryonic and Adult Forebrain Neurogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022; 42:8373-8392..
Model-informed precision dosing for alemtuzumab in paediatric and young adult patients undergoing allogeneic haematopoietic cell transplantation. British Journal of Clinical Pharmacology. 2022; 88:248-259..
2022; 140:8168-8169.. Hydroxyurea Pharmacokinetics in Young Children with Sickle Cell Anemia: Results from the Therapeutic Response Evaluation and Adherence Trial (TREAT). Blood.
2022; 140:8256-8257.. Evaluation of Dosage and Food Effect on L-Glutamine Exposure for Sickle Cell Anemia: A Population Pharmacokinetic Analysis. Blood.
Morbidity, Mortality, and Therapeutics in Combined Immunodeficiency: Data From the USIDNET Registry. Journal of Allergy and Clinical Immunology: In Practice. 2022; 10:1334-1341.e6..
Influence of CYP2D6 metabolizer status on ondansetron efficacy in pediatric patients undergoing hematopoietic stem cell transplantation: A case series. Clinical and Translational Science. 2022; 15:610-618..
Formation of the Mouse Internal Capsule and Cerebral Peduncle: A Pioneering Role for Striatonigral Axons as Revealed in Isl1 Conditional Mutants. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022; 42:3344-3364..
Early stool microbiome and metabolome signatures in pediatric patients undergoing allogeneic hematopoietic cell transplantation. Pediatric Blood and Cancer. 2022; 69:e29384..
Epstein Barr virus-mediated transformation of B cells from XIAP-deficient patients leads to increased expression of the tumor suppressor CADM1. Cell Death and Disease. 2022; 13:892..
Tisagenlecleucel outcomes in relapsed/refractory extramedullary ALL: a Pediatric Real World CAR Consortium Report. Blood Advances. 2022; 6:600-610..
Differential CXCR4 expression on hematopoietic progenitor cells versus stem cells directs homing and engraftment. JCI insight. 2022; 7:e151847..
Asymmetric division: the choice of fate for huHSCs. Blood. 2022; 139:1930-1932..
2022; 142:b36.. LB1033 Thrombin contributes to atopic dermatitis pathogenesis and staphylococcus aureus skin colonization in children. Journal of Investigative Dermatology.
Management of neurofibromatosis type 1-associated plexiform neurofibromas. Neuro-Oncology. 2022; 24:1827-1844..
Reduced Intensity Conditioning Allogeneic Transplant for SCID Associated with Cartilage Hair Hypoplasia. Journal of Clinical Immunology. 2022; 42:1604-1607..
Safety, Pharmacokinetics, and Pharmacodynamics of Etavopivat (FT-4202), an Allosteric Activator of Pyruvate Kinase-R, in Healthy Adults: A Randomized, Placebo-Controlled, Double-Blind, First-in-Human Phase 1 Trial. Clinical Pharmacology in Drug Development. 2022; 11:654-665..
Regulation of chromatin accessibility by the histone chaperone CAF-1 sustains lineage fidelity. Nature Communications. 2022; 13:2350..
Hematologic complications with age in Shwachman-Diamond syndrome. Blood Advances. 2022; 6:297-306..
2022; 28:s374-s375.. 477 Availability of Donor Derived Patient Specific Virus-Specific T-Cells (VSTs) Is Not Associated with Differences in Outcomes As Compared to Frontline Administration of Third Party Vsts for the Management of Viral Infections after Pediatric Hematopoietic Stem Cell Transplant. Transplantation and cellular therapy.
Coronavirus disease 2019 and vaccination in patients with Shwachman-Diamond syndrome. Pediatric Blood and Cancer. 2022; 69:e29647..
Safety and Efficacy of Prophylactic Levofloxacin in Pediatric and Adult Hematopoietic Stem Cell Transplantation Patients. Transplantation and cellular therapy. 2022; 28:167.e1-167.e5..
Chromatin structure predicts survival in glioma patients. Scientific Reports. 2022; 12:8221..
Bayesian regularization for a nonstationary Gaussian linear mixed effects model. Statistics in Medicine. 2022; 41:681-697..
Springer Nature; Springer Nature; 2022.. Pediatric Renal Tumors. Pediatric Nephrology. :
Insane in the membrane: A case of hereditary spherocytic pyropoikilocytosis. American Journal of Hematology. 2022; 97:1384-1385..
Effect of Anticoagulant Therapy for 6 Weeks vs 3 Months on Recurrence and Bleeding Events in Patients Younger Than 21 Years of Age With Provoked Venous Thromboembolism: The Kids-DOTT Randomized Clinical Trial. Journal of the American Medical Association. 2022; 327:129-137..
The Need for New Treatments Targeting MPNST: The Potential of Strategies Combining MEK Inhibitors with Antiangiogenic Agents. Clinical Cancer Research. 2022; 28:3185-3195..
Role of the hematopoietic stem cells in immunological memory. Current stem cell reports. 2022; 8:35-43..
2022; 140:2224.. Lasting Hematopoietic Memory Induced By Gestational Diabetes Contributes to Atherosclerosis Development in Adult Offspring. Blood.
LAMP-5 is an essential inflammatory-signaling regulator and novel immunotherapy target for mixed lineage leukemia-rearranged acute leukemia. Haematologica: the hematology journal. 2022; 107:803-815..
The Consortium on Newborn Screening in Africa for sickle cell disease: study rationale and methodology. Blood Advances. 2022; 6:6187-6197..
In silico gene expression and pathway analysis of DEK in the human brain across the lifespan. European Journal of Neuroscience. 2022; 56:4720-4743..
Novel molecular mechanisms in Alzheimer's disease: The potential role of DEK in disease pathogenesis. Frontiers in Aging Neuroscience. 2022; 14:1018180..
2022; 30:s95.. A MODIFIED COMPREHENSIVE GRADING SYSTEM FOR MURINE KNEE OSTEOARTHRITIS: SCORING THE WHOLE JOINT AS AN ORGAN. Osteoarthritis and Cartilage.
β-catenin cancer-enhancing genomic regions axis is involved in the development of fibrolamellar hepatocellular carcinoma. Hepatology Communications. 2022; 6:2950-2963..
Multi-institutional analysis of central nervous system germ cell tumors in patients with Down syndrome. Pediatric Blood and Cancer. 2022; 69:e29830..
Identification of new RAD51D-regulating microRNAs that also emerge as potent inhibitors of the Fanconi anemia/homologous recombination pathways. Human Molecular Genetics. 2022; 31:4241-4254..
Selection of lung transplant candidates: A pediatric perspective on the International Society for Heart and Lung Transplantation consensus document. Journal of Heart and Lung Transplantation. 2022; 41:998-999..
Tissue-localized immune responses in people with cystic fibrosis and respiratory nontuberculous mycobacteria infection. JCI insight. 2022; 7:e157865..
Novel blood derived hemostatic agents for bleeding therapy and prophylaxis. Current Opinion in Hematology. 2022; 29:281-289..
2022; 140:10857-10859.. Optimizing Shared Decision Making about Hydroxyurea in Young Children with Sickle Cell Anemia. Blood.
The influence of perceived racial bias and health-related stigma on quality of life among children with sickle cell disease. Ethnicity and Health. 2022; 27:833-846..
2022; 140:5830.. UBE2N Is a Druggable Target and an Essential Ubiquitin-Conjugating Enzyme in Myeloid Malignancies. Blood.
Novel MRI deformation-heterogeneity radiomic features are associated with molecular subgroups and overall survival in pediatric medulloblastoma: Preliminary findings from a multi-institutional study. Frontiers in Oncology. 2022; 12:915143..
Transforming growth factor-β signaling modifies the hematopoietic acute inflammatory response to drive bone marrow failure. Haematologica: the hematology journal. 2022; 107:1323-1334..
IKAROS and MENIN in synergy in AML. 2022; 3:528-529..
2022; 81:102266.. Total pancreatectomy with islet autotransplantation in a child with pancreatic kaposiform hemangioendothelioma. Journal of Pediatric Surgery Case Reports.
Targeting of Cdc42 GTPase in regulatory T cells unleashes antitumor T-cell immunity. Journal for ImmunoTherapy of Cancer. 2022; 10:e004806..
Quality Improvement in Hematopoietic Stem Cell Transplant and Cellular Therapy: Using the Model for Improvement to impact Outcomes. Transplantation and cellular therapy. 2022; 28:233-241..
Early hydroxyurea use is neuroprotective in children with sickle cell anemia. American Journal of Hematology. 2022; 97:E368-E370..
Potentiation of temozolomide activity against glioblastoma cells by aromatase inhibitor letrozole. Cancer Chemotherapy and Pharmacology. 2022; 90:345-356..
Rac-deficient cerebellar granule neurons die before they migrate to the internal granule layer. Scientific Reports. 2022; 12:14848..
Multiple Nf1 Schwann cell populations reprogram the plexiform neurofibroma tumor microenvironment. JCI insight. 2022; 7:e154513..
Multifocal Trichosporon asahii Infection in a Patient With Chronic Granulomatous Disease. Journal of the Pediatric Infectious Diseases Society. 2022; 11:467-470..
2022; 7:100100.. Prospective two center study of CD38 bright CD8+ effector memory T-cells as a predictor of acute GVHD. Transplantation Reports.
A Murine Model of Veno-Arterial Extracorporeal Membrane Oxygenation. ASAIO Journal. 2022; 68:e243-e250..
WNT5A-RHOA Signaling Is a Driver of Tumorigenesis and Represents a Therapeutically Actionable Vulnerability in Small Cell Lung Cancer. Cancer Research. 2022; 82:4219-4233..
Integration of single-cell transcriptomes and biological function reveals distinct behavioral patterns in bone marrow endothelium. Nature Communications. 2022; 13:7235..
Pain, depressive symptoms, and health-related quality of life among survivors of pediatric hematopoietic stem cell transplant. Pediatric Blood and Cancer. 2022; 69:e29846..
Synergistic anti-tumor efficacy of mutant isocitrate dehydrogenase 1 inhibitor SYC-435 with standard therapy in patient-derived xenograft mouse models of glioma. Translational Oncology. 2022; 18:101368..
Successful use of veno-venous extracorporeal membrane oxygenation for acute chest syndrome in a child with sickle cell disease and SARS-CoV-2. Pediatric Pulmonology. 2022; 57:1096-1099..
Secondary Impact of the Coronavirus Disease 19 Pandemic on Patients and the Cellular Therapy Healthcare Ecosystem. Transplantation and cellular therapy. 2022; 28:737-746..
Risk factors for treatment-refractory and relapsed optic pathway glioma in children with neurofibromatosis type 1. Neuro-Oncology. 2022; 24:1377-1386..
2022; 6:07-08.. O-12: BUILDING LOCAL CAPACITY FOR HYDROXYUREA PHARMACOKINETICS AND PRECISION DOSING IN LOW-RESOURCE SETTINGS. HemaSphere.
2022; 140:6102-6103.. Phase I Study of Tagraxofusp with or without Chemotherapy in Pediatric Patients with Relapsed or Refractory CD123-Expressing Hematologic Malignancies: A Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL) Consortium Trial. Blood.
Conditional information and inference in response-adaptive allocation designs. Statistics in Medicine. 2022; 41:390-406..
2022; 114:1074.. Neurocognitive outcomes in pediatric brain tumor survivors treated with proton radiotherapy: a study from the Pediatric Proton/Photon Consortium Registry (PPCR). International Journal of Radiation: Oncology - Biology - Physics.
Accuracy of central neuro-imaging review of DIPG compared with histopathology in the International DIPG Registry. Neuro-Oncology. 2022; 24:821-833..
Immunohistochemical assessment and clinical, histopathologic, and molecular correlates of membranous somatostatin type-2A receptor expression in high-risk pediatric central nervous system tumors. Frontiers in Oncology. 2022; 12:996489..
PRMT3 drives glioblastoma progression by enhancing HIF1A and glycolytic metabolism. Cell Death and Disease. 2022; 13:943..
An In Vivo CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML. Cancer Discovery. 2022; 12:432-449..
Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness. Jove-Journal of Visualized Experiments. 2022..
2022; 6:978-979.. P1088: UPDATED DATA FROM A PHASE 1/2 STUDY OF BRENTUXIMAB VEDOTIN COMBINED WITH CHEMOTHERAPY IN PEDIATRIC PATIENTS WITH ADVANCED STAGE CLASSICAL HODGKIN LYMPHOMA. HemaSphere.
A few comments about benign esophageal strictures. Gastrointestinal Endoscopy. 2022; 95:1020..
Some Issues Considered for Clip Closure After Endoscopic Resection of Large Serrated Polyps. Clinical Gastroenterology and Hepatology. 2022; 20:2656..
Long-term outcomes of refractory esophageal strictures after endoscopic submucosal dissection of superficial esophageal neoplasms. BMC Gastroenterology. 2022; 22:147..
Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis. Nature. 2022; 612:787-794..
Retroflexed view for reexamination of the right colon after forward view examination: Systematic review and meta-analysis. Digestive Endoscopy. 2022; 34:33-42..
Cap-assisted endoscopic full-thickness resection for small gastrointestinal stromal tumors. Gastrointestinal Endoscopy. 2022; 95:810-811..
2022; 24:vii164-vii165.. NIMG-16. COMPARISON OF A STIR- AND T1-WEIGHTED-BASED RADIOMICS MODEL TO DIFFERENTIATE BETWEEN PLEXIFORM NEUROFIBROMAS AND MALIGNANT PERIPHERAL NERVE SHEATH TUMORS IN NEUROFIBROMATOSIS TYPE 1 (NF1). Neuro-Oncology.
Anchoring IgG-degrading enzymes to the surface of platelets selectively neutralizes antiplatelet antibodies. Blood Advances. 2022; 6:4645-4656..
2022; 6:02-03.. O-03: ETAVOPIVAT TREATMENT FOR UP TO 12 WEEKS IN PATIENTS WITH SICKLE CELL DISEASE IS WELL TOLERATED AND IMPROVES RED BLOOD CELL HEALTH. HemaSphere.
2022; 7:188.. Case Report: β-thalassemia major on the East African coast. Wellcome Open Research.
2022; 174:s28-s29.. 82 (PB072) Phase I dose-escalation study of the pan-PI3 K inhibitor copanlisib in children and adolescents with relapsed/refractory solid tumors. European Journal of Cancer.
GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas. Nature. 2022; 603:934-941..
Blood diseases in Africa: Redressing unjust disparities is an urgent unmet need. American Journal of Hematology. 2022; 97:1505-1506..
Does shining a spotlight on XIAP deficiency bring the role of allogeneic HCT into better focus?. Journal of Allergy and Clinical Immunology. 2022; 150:297-298..
Comparison of hematopoietic cell transplant conditioning regimens for hemophagocytic lymphohistiocytosis disorders. Journal of Allergy and Clinical Immunology. 2022; 149:1097-1104.e2..
Skeletal muscle mass as a marker to predict outcomes in children and young adults with cancer. Abdominal Radiology. 2022; 47:452-459..
Adherence and Barriers to Inpatient Physical Therapy Among Adolescents and Young Adults with Hematologic Malignancies. Journal of Adolescent and Young Adult Oncology. 2022; 11:605-610..
Results of an international survey on adherence with anticoagulation in children, adolescents, and young adults: Communication from the ISTH SSC Subcommittee on Pediatric and Neonatal Thrombosis and Hemostasis. Journal of Thrombosis and Haemostasis. 2022; 20:1720-1728..
The Role of Complement in HSCT-TMA: Basic Science to Clinical Practice. Advances in Therapy. 2022; 39:3896-3915..
Chemotherapy-induced thrombocytopenia in Ewing sarcoma: Implications and potential for romiplostim supportive care. Pediatric Blood and Cancer. 2022; 69:e29548..
Radiation Therapy for Young Children Treated With High-Dose Chemotherapy and Autologous Stem Cell Transplant for Primary Brain Tumors. Advances in Radiation Oncology. 2022; 7:100945..
2022; 140:2185-2186.. Severe Adverse Events Associated with Concentrations of High Dose Methotrexate in Pediatric Acute Lymphoblastic Leukemia Patients. Blood.
2022; 28:s154-s155.. 187 Eculizumab Precision Dosing Algorithm for TA-TMA in Children and Young Adults Undergoing Stem Cell Transplant. Transplantation and cellular therapy.
Eculizumab precision-dosing algorithm for thrombotic microangiopathy in children and young adults undergoing HSCT. Blood Advances. 2022; 6:1454-1463..
Antibodies against biotin-labeled red blood cells can shorten posttransfusion survival. Transfusion. 2022; 62:770-782..
2022; 208:119.11.. Tumors bearing defective transcription elongation are immune hot but resistant to immune checkpoint inhibitors. Journal of immunology (Baltimore, Md. : 1950).
Transplanting rejuvenated blood stem cells extends lifespan of aged immunocompromised mice. npj Regenerative Medicine. 2022; 7:78..
Real-world use of tisagenlecleucel in infant acute lymphoblastic leukemia. Blood Advances. 2022; 6:4251-4255..
Defective transcription elongation in human cancers imposes targetable proteotoxic vulnerability. Translational Oncology. 2022; 16:101323..
AMPK in the brain: its roles in glucose and neural metabolism. FEBS Journal. 2022; 289:2247-2262..
TRAF6 functions as a tumor suppressor in myeloid malignancies by directly targeting MYC oncogenic activity. Cell Stem Cell. 2022; 29:298-314.e9..
2022; 12:11-28.. Health Related Quality of Life among Children with Sickle Cell Anaemia in Northwestern Tanzania.
Aging of intestinal stem cells. Stem Cell Reports. 2022; 17:734-740..
Acquired and hereditary bone marrow failure: A mitochondrial perspective. Frontiers in Oncology. 2022; 12:1048746..
Nuclear Vav3 is required for polycomb repression complex-1 activity in B-cell lymphoblastic leukemogenesis. Nature Communications. 2022; 13:3056..
The deubiquitinase USP15 modulates cellular redox and is a therapeutic target in acute myeloid leukemia. Leukemia. 2022; 36:438-451..
Assessment of Plasmodium falciparum Artemisinin Resistance Independent of kelch13 Polymorphisms and with Escalating Malaria in Bangladesh. Editor, Bhanot P. mBio. 2022; 13:e0344421..
Elsevier; Elsevier; 2022.. Chapter 3 Classification and diagnosis of anemia in children and neonates. Lanzkowsky's Manual of Pediatric Hematology and Oncology. :
M-CSF supports medullary erythropoiesis and erythroid iron demand following burn injury through its activity on homeostatic iron recycling. Scientific Reports. 2022; 12:1235..
Rapid degradation of protein tyrosine phosphatase 1B in sickle cells: Possible contribution to sickle cell membrane weakening. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2022; 36:e22360..
(2022) Phase II Trial of Inotuzumab Ozogamicin in Children and Adolescents With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia: Children's Oncology Group Protocol AALL1621. American Society of Clinical Oncology (ASCO). 40:956-967..
The ASH-ASPHO Choosing Wisely Campaign: 5 hematologic tests and treatments to question. Blood Advances. 2022; 6:679-685..
Optimized amplification of BK polyomavirus in urine. Journal of Virological Methods. 2022; 299:114319..
BK Polyomavirus Subtypes II and IV in Hematopoietic Cell Transplant Recipients. Editor, Roux S. Microbiology Resource Announcements. 2022; 11:e0105321..
2022; 4:i22.. SYST-07 WINDOW-OF-OPPORTUNITY STUDY OF ONC201 IN PEDIATRIC PATIENTS WITH DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) AND THALAMIC GLIOMA. NOA.
Freeze-dried platelets are a promising alternative in bleeding thrombocytopenic patients with hematological malignancies. American Journal of Hematology. 2022; 97:256-266..
Rheumatologic diseases in patients with inborn errors of immunity in the USIDNET registry. Clinical Rheumatology. 2022; 41:2197-2203..
Crosstalk between hemostasis and immunity in cancer pathogenesis. Thrombosis Research. 2022; 213 Suppl 1:S3-S7..
Anticoagulation in pediatric cancer-associated venous thromboembolism: a subgroup analysis of EINSTEIN-Jr. Blood Advances. 2022; 6:5821-5828..
Chronic pediatric diseases and risk for reading difficulties: a narrative review with recommendations. Pediatric Research. 2022; 92:966-978..
Decitabine and vorinostat with FLAG chemotherapy in pediatric relapsed/refractory AML: Report from the therapeutic advances in childhood leukemia and lymphoma (TACL) consortium. American Journal of Hematology. 2022; 97:613-622..
The evolution of targeted therapy in pediatric AML: gemtuzumab ozogamicin, FLT3/IDH/BCL2 inhibitors, and other therapies. Hematology-American Society of Hematology Education Program. 2022; 2022:603-610..
US News & World Report and quality metrics: Inclusion of sickle cell disease is a matter of equity. Pediatric Blood and Cancer. 2022; 69:e29679..
Reproductive equity: preserve the reserve. Blood. 2022; 139:963-965..
New therapeutics for children with sickle cell disease: A time for celebration, caution, or both?. Pediatric Blood and Cancer. 2022; 69:e29805..
2022; 6:13.. PI-08: HIGH DISEASE BURDEN, MORBIDITY AND MORTALITY AMONG CHILDREN WITH SICKLE CELL ANAEMIA IN UGANDA. HemaSphere.
Glioblastoma genetic drivers dictate the function of tumor-associated macrophages/microglia and responses to CSF1R inhibition. Neuro-Oncology. 2022; 24:584-597..
An Immersive Virtual Reality Curriculum for Pediatric Hematology Clinicians on Shared Decision-making for Hydroxyurea in Sickle Cell Anemia. Journal of Pediatric Hematology/Oncology. 2022; 44:e799-e803..
How we approach the diagnosis and management of complex lymphatic anomalies. Pediatric Blood and Cancer. 2022; 69 Suppl 3:e28985..
Erythroblastic islands foster granulopoiesis in parallel to terminal erythropoiesis. Blood. 2022; 140:1621-1634..
BIRC2-BIRC3 amplification: a potentially druggable feature of a subset of head and neck cancers in patients with Fanconi anemia. Scientific Reports. 2022; 12:45..
Off-the-Shelf Third-Party Virus-Specific T Cell Therapy to Treat JC Polyomavirus Infection in Hematopoietic Stem Cell Transplantation Recipients. Transplantation and cellular therapy. 2022; 28:116.e1-116.e7..
Scheduled administration of virus-specific T cells for viral prophylaxis after pediatric allogeneic stem cell transplant. Blood Advances. 2022; 6:2897-2907..
Circulating endothelial cells and the study of vascular injury in children undergoing hematopoietic stem cell transplant. Haematologica: the hematology journal. 2022; 107:2950-2954..
Cerebral vascular injury in transplant-associated thrombotic microangiopathy. Blood Advances. 2022; 6:4310-4319..
Acute myeloid leukemia in SRP54-mutated congenital neutropenia. 2022; 3:521-525..
What complements complement in transplant-associated thrombotic microangiopathy?. British Journal of Haematology. 2022; 199:477-479..
Diagnostic Considerations in H1N1 Influenza-induced Thrombotic Microangiopathy. Journal of Pediatric Hematology/Oncology. 2022; 44:e237-e240..
Azithromycin does not increase hematologic relapse in pediatric hematopoietic cell transplant recipients. Bone Marrow Transplantation. 2022; 57:1589-1591..
Whole-exome analysis of adolescents with low VWF and heavy menstrual bleeding identifies novel genetic associations. Blood Advances. 2022; 6:420-428..
Characteristics of Graft-Versus-Host Disease (GvHD) After Post-Transplantation Cyclophosphamide Versus Conventional GvHD Prophylaxis. Transplantation and cellular therapy. 2022; 28:681-693..
Small cell carcinoma of the ovary hypercalcemic type (SCCOHT): A review and novel case with dual germline SMARCA4 and BRCA2 mutations. Gynecologic Oncology Reports. 2022; 44:101077..
Cell origin-dependent cooperativity of mutant Dnmt3a and Npm1 in clonal hematopoiesis and myeloid malignancy. Blood Advances. 2022; 6:3666-3677..
2022; 140:10693-10694.. High Throughput Pre-Clinical Models to Determine a Synergistic Molar Ratio of 5-Azacitidine to Venetoclax and Uncover Resistance Mechanisms to 5-Azacitidine and Venetoclax Combination Therapy in Acute Myeloid Leukemia. Blood.
Real-world experience in treating pediatric relapsed/refractory or therapy-related myeloid malignancies with decitabine, vorinostat, and FLAG therapy based on a phase 1 study run by the TACL consortium. Pediatric Blood and Cancer. 2022; 69:e29812..
Posterior Reversible Encephalopathy Syndrome in the Setting of Asparaginase-associated Pancreatitis in 2 Pediatric Patients With Acute Leukemia. Journal of Pediatric Hematology/Oncology. 2022; 44:e709-e712..
A human STAT3 gain-of-function variant confers T cell dysregulation without predominant Treg dysfunction in mice. JCI insight. 2022; 7:e162695..
A transcription factor is the target of propranolol treatment in infantile hemangioma. The Journal of Clinical Investigation. 2022; 132:e156863..
Etavopivat, a Pyruvate Kinase Activator in Red Blood Cells, for the Treatment of Sickle Cell Disease. The Journal of pharmacology and experimental therapeutics. 2022; 380:210-219..
Disease Burden Affects Outcomes in Pediatric and Young Adult B-Cell Lymphoblastic Leukemia After Commercial Tisagenlecleucel: A Pediatric Real-World Chimeric Antigen Receptor Consortium Report. Journal of Clinical Oncology. 2022; 40:945-955..
How we approach genetics in the diagnosis and management of vascular anomalies. Pediatric Blood and Cancer. 2022; 69 Suppl 3:e29320..
2022; 140:8190-8191.. Dominant-Negative VPS4A Mutations Causing Congenital Dyserythropoietic Anemia Disrupt Iron Trafficking of Terminal Erythropoiesis. Blood.
Granulocyte Colony-Stimulating Factor Is Safe and Well Tolerated following Allogeneic Transplantation in Patients with Sickle Cell Disease. Transplantation and cellular therapy. 2022; 28:174.e1-174.e5..
Shared and disease-sensitive dysfunction across bipolar and unipolar disorder during depressive episodes: a transdiagnostic study. Neuropsychopharmacology. 2022; 47:1922-1930..
2022; 2:877717.. A Brief Review on Deep Learning Applications in Genomic Studies.
2022; 140:13141-13142.. A Health Equity Echo for Providers of Children and Adults with Sickle Cell Disease. Blood.
Expanding a Regional Sickle Cell Disease Project ECHO® to Rapidly Disseminate COVID-19 Education. Advances in Medical Education and Practice. 2022; 13:443-447..
2022; 21:s328.. 591 Modulation of the deoxyribonucleic acid nanoparticle interactome enhances cystic fibrosis transmembrane conductance regulator gene transfer in a cystic fibrosis mouse model. Journal of Cystic Fibrosis.
Detection of cytogenetic changes and chromosomal aneuploidy with fluorescent in situ hybridization in cytological specimens of oral cancers in Fanconi anemia-Proof of concept. Clinical and Experimental Dental Research. 2022; 8:108-116..
Post-Transplantation Cyclophosphamide Is Associated with an Increase in Non-Cytomegalovirus Herpesvirus Infections in Patients with Acute Leukemia and Myelodysplastic Syndrome. Transplantation and cellular therapy. 2022; 28:48.e1-48.e10..
Drug resistance mechanisms create targetable proteostatic vulnerabilities in Her2+ breast cancers. Editor, Dey N. PloS one. 2022; 17:e0256788..
2022; 21:s101-s102.. 174 Identification of physiological characteristics at baseline and 1 and 6 months that segregate lung function response to ivacaftor using proteomic analysis. Journal of Cystic Fibrosis.
2022; 21:s84.. 143 Bronchoalveolar lavage proteome identifies pathways of disease that segregate lung transplant recipients with and without bronchiolitis obliterans syndrome. Journal of Cystic Fibrosis.
Inborn Errors of Immunity Associated With Type 2 Inflammation in the USIDNET Registry. Frontiers in Immunology. 2022; 13:831279..
Preclinical Evaluation of Foamy Virus Vector-Mediated Gene Addition in Human Hematopoietic Stem/Progenitor Cells for Correction of Leukocyte Adhesion Deficiency Type 1. Human Gene Therapy. 2022; 33:1293-1304..
2022; 24:s159.. eP250: Molecular findings in patients with atypical Sturge-Weber syndrome. Genetics in Medicine.
2022; 140:1981-1982.. Hematopoietic Flt3+ Multipotent Progenitors Are Organized in Discrete Functionally and Hierarchically Distinct Populations. Blood.
Hepatoblastomas with carcinoma features represent a biological spectrum of aggressive neoplasms in children and young adults. Journal of Hepatology. 2022; 77:1026-1037..
An Investigation into the Association Between Dopamine Receptor D1 Multilocus Genetic Variation, Multiparametric Magnetic Resonance Imaging, and Antidepressant Treatment. Journal of Magnetic Resonance Imaging. 2022; 56:282-290..
Bone Health Outcomes at 1 Year after Hematopoietic Stem Cell Transplantation in a Heterogeneous Pediatric Population. Transplantation and cellular therapy. 2022; 28:44.e1-44.e6..
2022; 6:43-44.. P-055: TRIAL IN PROGRESS: A PHASE 2, OPEN-LABEL STUDY EVALUATING THE SAFETY AND EFFICACY OF THE ERYTHROCYTE PYRUVATE KINASE ACTIVATOR ETAVOPIVAT IN PATIENTS WITH THALASSEMIA OR SICKLE CELL DISEASE. HemaSphere.
Excessive IL-10 and IL-18 trigger hemophagocytic lymphohistiocytosis-like hyperinflammation and enhanced myelopoiesis. Journal of Allergy and Clinical Immunology. 2022; 150:1154-1167..
Agreement between serum estimates of glomerular filtration rate (GFR) and a reference standard of radioisotopic GFR in children with cancer. Pediatric Radiology: roentgenology, nuclear medicine, ultrasonics, CT, MRI. 2022; 52:903-909..
Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia. Blood. 2022; 140:1875-1890..
A systematic review of adherence to anticoagulation regimens in pediatric patients. Pediatric Blood and Cancer. 2022; 69:e29698..
Preemptive hematopoietic cell transplantation for asymptomatic patients with X-linked lymphoproliferative syndrome type 1. Clinical Immunology. 2022; 237:108993..
Altered erythropoiesis in newborns with congenital heart disease. Pediatric Research. 2022; 91:606-611..
Role of ATP-dependent chromatin remodelers in hematopoietic stem and progenitor cell maintenance. Current Opinion in Hematology. 2022; 29:174-180..
Acute GVHD, BK virus hemorrhagic cystitis and age are risk factors for transplant-associated thrombotic microangiopathy in adults. Blood Advances. 2022; 6:1342-1349..
NMR-based metabolomic analysis identifies RON-DEK-β-catenin dependent metabolic pathways and a gene signature that stratifies breast cancer patient survival. Editor, Samant R. PloS one. 2022; 17:e0274128..
A Limited Role for AMD3100 Induced Stem Cell Mobilization for Modulation of Thoracic Trauma Outcome. Shock. 2022; 57:260-267..
2022; 140:1234-1235.. De Novo Germline DHX38 Variant Associated with Alternative Splicing of Multiple Transcripts in Iron-Related Pathways in a Patient with Atypical Congenital Dyserythropoietic Anemia with Ring Sideroblasts. Blood.
Use of thromboelastography in children on extracorporeal membrane oxygenation. Journal of Pediatric Surgery. 2022; 57:1056-1061..
Dynamic connectivity alterations in anterior cingulate cortex associated with suicide attempts in bipolar disorders with a current major depressive episode. Journal of Psychiatric Research. 2022; 149:307-314..
Spontaneous Facet Joint Osteoarthritis in NFAT1-Mutant Mice: Age-Dependent Histopathologic Characteristics and Molecular Mechanisms. The Journal of Bone and Joint Surgery. 2022; 104:928-940..
Olig2 Ablation in Immature Oligodendrocytes Does Not Enhance CNS Myelination and Remyelination. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022; 42:8542-8555..
Association Between Antidepressant Efficacy and Interactions of Three Core Depression-Related Brain Networks in Major Depressive Disorder. Frontiers in Psychiatry. 2022; 13:862507..
Predicting Treatment Selections for Individuals with Major Depressive Disorder According to Functional Connectivity Subgroups. Brain Connectivity. 2022; 12:699-710..
Reply to: Comment on: Hematopoietic stem cell transplant for erythropoietic porphyrias in pediatric patients. Pediatric Blood and Cancer. 2022; 69:e29432..
Ruxolitinib for the Treatment of Chronic GVHD and Overlap Syndrome in Children and Young Adults. Transplantation. 2022; 106:412-419..
Genomic signature of Fanconi anaemia DNA repair pathway deficiency in cancer. Nature. 2022; 612:495-502..
The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia. Cancer Cell. 2022; 40:1566-1582.e10..
Cognitive and behavioral effects of whole brain conventional or high dose rate (FLASH) proton irradiation in a neonatal Sprague Dawley rat model. Editor, Lee J. PloS one. 2022; 17:e0274007..
Pediatric 129 Xe Gas-Transfer MRI-Feasibility and Applicability. Journal of Magnetic Resonance Imaging. 2022; 56:1207-1219..
Single-cell multiomics identifies clinically relevant mesenchymal stem-like cells and key regulators for MPNST malignancy. Science Advances. 2022; 8:eabo5442..
2022; 2022.01.31.478534.. PDX models of relapsed pediatric AML preserve global gene expression patterns and reveal therapeutic targets.
Effect of TDP43-CTFs35 on Brain Endothelial Cell Functions in Cerebral Ischemic Injury. Molecular Neurobiology. 2022; 59:4593-4611..
Aberrant functional connectivity in insular subregions in somatic depression: a resting-state fMRI study. BMC Psychiatry. 2022; 22:146..
Alterations of regional spontaneous neuronal activity and corresponding brain circuits related to non-suicidal self-injury in young adults with major depressive disorder. Journal of Affective Disorders. 2022; 305:8-18..
The Impact of Inflammation-Induced Tumor Plasticity during Myeloid Transformation. Cancer Discovery. 2022; 12:2392-2413..
PRC2 Heterogeneity Drives Tumor Growth in Medulloblastoma. Cancer Research. 2022; 82:2874-2886..
Regulation of Cdc42 signaling by the dopamine D2 receptor in a mouse model of Parkinson's disease. Aging Cell. 2022; 21:e13588..
Spontaneous transient states of fronto-temporal and default-mode networks altered by suicide attempt in major depressive disorder. European Archives of Psychiatry and Clinical Neuroscience: official organ of the German society for biological psychiatry. 2022; 272:1547-1557..
Innate immune mediator, Interleukin-1 receptor accessory protein (IL1RAP), is expressed and pro-tumorigenic in pancreatic cancer. Journal of Hematology and Oncology. 2022; 15:70..
A multifaceted evaluation of microgliosis and differential cellular dysregulation of mammalian target of rapamycin signaling in neuronopathic Gaucher disease. Frontiers in Molecular Neuroscience. 2022; 15:944883..
Opioid receptor signaling suppresses leukemia through both catalytic and non-catalytic functions of TET2. Cell Reports. 2022; 38:110253..
Interoception Dysfunction Contributes to the Negative Emotional Bias in Major Depressive Disorder. Frontiers in Psychiatry. 2022; 13:874859..
Chronotype, circadian rhythm, and psychiatric disorders: Recent evidence and potential mechanisms. Frontiers in Neuroscience. 2022; 16:811771..