Childhood neurological and psychiatric disorders can have devastating impacts on the lives of affected patients and their families. Further, despite the high incidence of diseases like autism, epilepsy and cerebral palsy, our understanding of disease mechanisms is limited, and treatments are all too often ineffective.
To gain fundamental insights into brain development that can be applied to treating childhood disorders, the Center for Pediatric Neuroscience (CPN) creates an environment that brings together basic scientists conducting fundamental, hypothesis-driven research with translational scientists developing new therapies and clinician-scientists working to bring these therapies to patients. The center recognizes and capitalizes on the bidirectional nature of the discovery process, with clinical needs inspiring translational and basic science research, and pure discovery-based research bringing transformational ideas and approaches to the clinic.
- Perform hypothesis-driven, discovery-based research in cellular, molecular and functional neuroscience to uncover fundamental mechanisms in nervous system development, repair and function.
- Identify and characterize genetic and environmental alterations that lead to childhood-onset nervous system disorders.
- Educate and mentor the next generation of basic- and clinical-neuroscience researchers. A world-class neuroscience program is defined by world-class faculty, therefore, the CPN is committed to recruit, developing and retain world-class faculty.
- Create bidirectional links with clinical neuroscience programs to translate basic research findings into innovative treatments for childhood nervous system disorders, and to elucidate basic mechanisms underlying novel clinical findings.
With almost 200 billion neurons and glia cells, and more than 100 trillion synapses, the human nervous system is the most complex structure science has attempted to understand. Correspondingly, disease of the nervous system, are, and will continue to be a pressing challenge for medical science for the foreseeable future. The goal of the Center for Pediatric Neuroscience is to position Cincinnati Children’s to meet these challenges, bringing fundamental and innovative neurodevelopmental discoveries to the world, and transformative care to children.