Developmental Biology

Abe, H; Alavattam, KG; Hu, Y; Pang, Q; Andreassen, PR; Hegde, RS; Namekawa, SH. The Initiation of Meiotic Sex Chromosome Inactivation Sequesters DNA Damage Signaling from Autosomes in Mouse Spermatogenesis. Current Biology. 2020; 30:408-420.e5.

Arlt, MF; Brogley, MA; Stark-Dykema, ER; Hu, Y; Mueller, JL. Genomic Structure, Evolutionary Origins, and Reproductive Function of a Large Amplified Intrinsically Disordered Protein-Coding Gene on the X Chromosome (Laidx) in Mice. G3-Genes Genomes Genetics. 2020; 10:1997-2005.

Azouz, NP; Klingler, AM; Pathre, P; Besse, JA; Ben Baruch-Morgenstern, N; Ballaban, AY; Osswald, GA; Brusilovsky, M; Habel, JE; Caldwell, JM; et al. Functional role of kallikrein 5 and proteinase-activated receptor 2 in eosinophilic esophagitis. Science Translational Medicine. 2020; 12:eaaz7773-eaaz7773.

Casie Chetty, S; Sumanas, S. Ets1 functions partially redundantly with Etv2 to promote embryonic vasculogenesis and angiogenesis in zebrafish. Developmental Biology. 2020; 465:11-22.

Cederquist, GY; Tchieu, J; Callahan, SJ; Ramnarine, K; Ryan, S; Zhang, C; Rittenhouse, C; Zeltner, N; Chung, SY; Zhou, T; et al. A Multiplex Human Pluripotent Stem Cell Platform Defines Molecular and Functional Subclasses of Autism-Related Genes. Cell Stem Cell. 2020; 27:35-49.e6.

Chestnut, B; Casie Chetty, S; Koenig, AL; Sumanas, S. Single-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle. Nature Communications. 2020; 11.

Chestnut, B; Sumanas, S. Zebrafish etv2 knock-in line labels vascular endothelial and blood progenitor cells. Developmental Dynamics. 2020; 249:245-261.

Elliott, KH; Chen, X; Salomone, J; Chaturvedi, P; Schultz, PA; Balchand, SK; Servetas, JD; Zuniga, A; Zeller, R; Gebelein, B; et al. Gli3 utilizes hand2 to synergistically regulate tissue-specific transcriptional networks. eLife. 2020; 9:1-33.

Emmert, AS; Vuong, SM; Shula, C; Lindquist, D; Yuan, W; Hu, Y; Mangano, FT; Goto, J. Characterization of a novel rat model of X-linked hydrocephalus by CRISPR-mediated mutation in L1cam. Journal of Neurosurgery. 2020; 132:945-958.

Fortriede, JD; Pells, TJ; Chu, S; Chaturvedi, P; Wang, D; Fisher, ME; James-Zorn, C; Wang, Y; Nenni, MJ; Burns, KA; et al. Xenbase: Deep integration of GEO & SRA RNA-seq and ChIP-seq data in a model organism database. Nucleic Acids Research. 2020; 48:D776-D782.

Han, L; Chaturvedi, P; Kishimoto, K; Koike, H; Nasr, T; Iwasawa, K; Giesbrecht, K; Witcher, PC; Eicher, A; Haines, L; et al. Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis. Nature Communications. 2020; 11.

Hegde, RS; Roychoudhury, K; Pandey, RN. The multi-functional eyes absent proteins. Critical Reviews in Biochemistry and Molecular Biology (Informa). 2020; 55:372-385.

Hinge, A; He, J; Bartram, J; Javier, J; Xu, J; Fjellman, E; Sesaki, H; Li, T; Yu, J; Wunderlich, M; et al. Asymmetrically Segregated Mitochondria Provide Cellular Memory of Hematopoietic Stem Cell Replicative History and Drive HSC Attrition. Cell Stem Cell. 2020; 26:420-430.e6.

Iwafuchi, M; Cuesta, I; Donahue, G; Takenaka, N; Osipovich, AB; Magnuson, MA; Roder, H; Seeholzer, SH; Santisteban, P; Zaret, KS. Gene network transitions in embryos depend upon interactions between a pioneer transcription factor and core histones. Nature Genetics. 2020; 52:418-427.

Kasendra, M; Wells, JM. A Window into Your Gut: Biologically Inspired Engineering of Mini-gut Tubes In Vitro. Developmental Cell. 2020; 55:522-524.

Kishimoto, K; Furukawa, KT; Luz-Madrigal, A; Yamaoka, A; Matsuoka, C; Habu, M; Alev, C; Zorn, AM; Morimoto, M. Bidirectional Wnt signaling between endoderm and mesoderm confers tracheal identity in mouse and human cells. Nature Communications. 2020; 11.

Kobia, FM; Preusse, K; Dai, Q; Weaver, N; Hass, MR; Chaturvedi, P; Stein, SJ; Pear, WS; Yuan, Z; Kovall, RA; et al. Notch dimerization and gene dosage are important for normal heart development, intestinal stem cell maintenance, and splenic marginal zone B-cell homeostasis during mite infestation. PLoS Biology. 2020; 18:e3000850-e3000850.

Kuang, Y; Golan, O; Preusse, K; Cain, B; Christensen, CJ; Salomone, J; Campbell, I; Okwubido-Williams, FV; Hass, MR; Yuan, Z; et al. Enhancer architecture sensitizes cell specific responses to Notch gene dose via a bind and discard mechanism. eLife. 2020; 9.

Li, C; Liu, H; Hu, Y; Lan, Y; Jiang, R. Generation and characterization of Six2 conditional mice. Genesis: the Journal of Genetics and Development. 2020; 58.

McCauley, HA. Enteroendocrine Regulation of Nutrient Absorption. The Journal of Nutrition. 2020; 150:10-21.

McCauley, HA; Matthis, AL; Enriquez, JR; Nichol, JT; Sanchez, JG; Stone, WJ; Sundaram, N; Helmrath, MA; Montrose, MH; Aihara, E; et al. Enteroendocrine cells couple nutrient sensing to nutrient absorption by regulating ion transport. Nature Communications. 2020; 11.

Mukherjee, S; Chaturvedi, P; Rankin, SA; Fish, MB; Wlizla, M; Paraiso, KD; MacDonald, M; Chen, X; Weirauch, MT; Blitz, IL; et al. Sox17 and b-catenin co-occupy wntresponsive enhancers to govern the endoderm gene regulatory network. eLife. 2020; 9:1-26.

Mukherjeel, M; Ratnayake, I; Janga, M; Fogarty, E; Scheidt, S; Grassmeyer, J; DeRiso, J; Chandrasekar, I; Ahrenkiel, SP; Kopan, R; et al. Notch signaling regulates Akap12 expression and primary cilia length during renal tubule morphogenesis. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020; 34:9512-9530.

Naert, T; Tulkens, D; Edwards, NA; Carron, M; Shaidani, NI; Wlizla, M; Boel, A; Demuynck, S; Horb, ME; Coucke, P; et al. Maximizing CRISPR/Cas9 phenotype penetrance applying predictive modeling of editing outcomes in Xenopus and zebrafish embryos. Scientific Reports. 2020; 10.

Nakafuku, M; del Aguila, A. Developmental dynamics of neurogenesis and gliogenesis in the postnatal mammalian brain in health and disease: Historical and future perspectives. Wiley Interdisciplinary Reviews: Developmental Biology. 2020; 9.

Nowrouzi, A; Sertorio, MG; Akbarpour, M; Knoll, M; Krunic, D; Kuhar, M; Schwager, C; Brons, S; Debus, J; Wells, SI; et al. Personalized assessment of normal tissue radiosensitivity via transcriptome response to photon, proton and carbon irradiation in patient-derived human intestinal organoids. Cancers. 2020; 12:469-469.

Pradhan, S; Karve, SS; Weiss, AA; Hawkins, J; Poling, HM; Helmrath, MA; Wells, JM; McCauley, HA. Tissue Responses to Shiga Toxin in Human Intestinal Organoids. CMGH Cellular and Molecular Gastroenterology and Hepatology. 2020; 10:171-190.

Rai, MA; Hammonds, J; Pujato, M; Mayhew, C; Roskin, K; Spearman, P. Comparative analysis of human microglial models for studies of HIV replication and pathogenesis. Retrovirology. 2020; 17.

Roychoudhury, K; Salomone, J; Qin, S; Cain, B; Adam, M; Pottert, SS; Nakafuku, M; Gebelein, B; Campbell, K. Physical interactions between Gsx2 and Ascl1 balance progenitor expansion versus neurogenesis in the mouse lateral ganglionic eminence. Development (Cambridge). 2020; 147:dev185348-dev185348.

Sakashita, A; Maezawa, S; Takahashi, K; Alavattam, KG; Yukawa, M; Hu, Y; Kojima, S; Parrish, NF; Barski, A; Pavlicev, M; et al. Endogenous retroviruses drive species-specific germline transcriptomes in mammals. Nature Structural and Molecular Biology. 2020; 27:967-977.

Schumacher, JA; Wright, ZA; Owen, ML; Bredemeier, NO; Sumanas, S. Integrin α5 and Integrin α4 cooperate to promote endocardial differentiation and heart morphogenesis. Developmental Biology. 2020; 465:46-57.

Seymour, PA; Collin, CA; Egeskov-Madsen, AL R; Jorgensen, MC; Shimojo, H; Imayoshi, I; de Lichtenberg, KH; Kopan, R; Kageyama, R; Serup, P. Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors. Developmental Cell. 2020; 52:731-747.e8.

Shacham-Silverberg, V; Wells, JM. Generation of esophageal organoids and organotypic raft cultures from human pluripotent stem cells. Methods in Cell Biology. : Elsevier; Elsevier; 2020.

Sharma, A; Verma, AK; Kofron, M; Kudira, R; Miethke, A; Wu, T; Wang, J; Gandhi, CR. Lipopolysaccharide Reverses Hepatic Stellate Cell Activation Through Modulation of cMyb, Small Mothers Against Decapentaplegic, and CCAAT/Enhancer-Binding Protein C/EBP Transcription Factors. Hepatology. 2020; 72:1800-1818.

Shen, C; Sheng, Y; Zhu, AC; Robinson, S; Jiang, X; Dong, L; Chen, H; Su, R; Yin, Z; Li, W; et al. RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia. Cell Stem Cell. 2020; 27:64-80.e9.

Tchieu, J; Urbán, N; Soragni, A; Kawaguchi, K; Blanchard, JW; Li, L. Introductions to the Community: Early-Career Researchers in the Time of COVID-19. Cell Stem Cell. 2020; 27:508-510.

Wu, Z; Parry, M; Hou, X; Liu, M; Wang, H; Cain, R; Pei, Z; Chen, Y; Guo, Z; Abhijeet, S; et al. Gene therapy conversion of striatal astrocytes into GABAergic neurons in mouse models of Huntington's disease. Nature Communications. 2020; 11.

Wu, Z; Parry, M; Hou, X; Liu, M; Wang, H; Cain, R; Pei, Z; Chen, Y; Guo, Z; Abhijeet, S; et al. Gene therapy conversion of striatal astrocytes into GABAergic neurons in mouse models of Huntington’s disease. Nature Communications. 2020; 11.

Xu, J; Liu, H; Lan, Y; Park, JS; Jiang, R. Genome-wide Identification of Foxf2 Target Genes in Palate Development. Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists. 2020; 99:463-471.

Yang, L; Slone, J; Li, Z; Lou, X; Hu, Y; Queme, LF; Jankowski, MP; Huang, T. Systemic administration of AAV-Slc25a46 mitigates mitochondrial neuropathy in Slc25a46^-/- mice. Human Molecular Genetics. 2020; 29:649-661.