Developmental Biology

Publications

Adhikari, N; Wu, Z; Huang, Y; Lan, Y; Jiang, R. Twist1 Acts Upstream of the Dlx5-Hand2 Pathway to Pattern the Mammalian Jaw. Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists. 2025; 104:310-319.

Bartusel, M; Kim, SX; Rehimi, R; Darnell, AM; Nikolić, M; Heggemann, J; Kolovos, P; van Ijcken, WF J; Varineau, J; Crispatzu, G; Laugsch, M; Ludwig, KU; Rada-Iglesias, A; Calo, E. A non-syndromic orofacial cleft risk locus links tRNA splicing defects to neural crest cell pathologies. The American Journal of Human Genetics. 2025; 112:1097-1116.

Cai, H; Tian, C; Chen, L; Yang, Y; Sun, AX; McCracken, K; Tchieu, J; Gu, M; Mackie, K; Guo, F. Vascular network-inspired diffusible scaffolds for engineering functional midbrain organoids. Cell Stem Cell. 2025; 32:824-837.e5.

Cederquist, GY; Oberst, P; Chang, X; Tchieu, J; Studer, L. Generation of Prefrontal Cortex Neurons from Human Pluripotent Stem Cells Under Chemically Defined Conditions. Synapse Development. : Springer US; Springer US; 2025.

Crossen, MJ; Jia, S; Jorgensen, JS; Kelleher, AM; Jiang, R; Zhao, F. Wnt9b enables androgen action to maintain Wolffian ducts in mice. Molecular Human Reproduction. 2025; 31:gaaf035.

Feuermann, M; Mi, H; Gaudet, P; Muruganujan, A; Lewis, SE; Ebert, D; Mushayahama, T; Westerfield, M; Ruzicka, L; Ramachandran, S; Skrzypek, MS; Nash, RS; Miyasato, SR; Karra, K. A compendium of human gene functions derived from evolutionary modelling. Nature. 2025; 640:146-154.

Hyatt, BA; Lundberg, E; Eye, R; Rankin, SA; Zorn, AM. Temporal induction of the homeodomain transcription factor Nkx2-1 is sufficient to respecify foregut and hindgut endoderm to a pulmonary fate in Xenopus laevis. microPublication Biology. 2025; 2025:10.17912/micropub.biology.

Matentzoglu, N; Bello, SM; Stefancsik, R; Alghamdi, SM; Anagnostopoulos, AV; Balhoff, JP; Balk, MA; Bradford, YM; Bridges, Y; Callahan, TJ; Haendel, MA; Mungall, CJ; McLaughlin, JA; Osumi-Sutherland, D. The Unified Phenotype Ontology : a framework for cross-species integrative phenomics. Editor, Baryshnikova A. Genetics: a periodical record of investigations bearing on heredity and variation. 2025; 229:iyaf027.

Miao, Y; Pek, NM; Tan, C; Jiang, C; Yu, Z; Iwasawa, K; Shi, M; Kechele, DO; Sundaram, N; Pastrana-Gomez, V; Zorn, AM; Chen, YW; Guo, M; Gu, M. Co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids. Cell. 2025; 188:4295-4313.e27.

Michaels, JR; Iyyanar, PP R; Husami, A; Vontell, AM; Brugmann, SA; Stottmann, RW. Genetic analysis and functional assessment of a TGFBR2 variant in micrognathia and cleft palate. Editor, Cray JJ. PloS one. 2025; 20:e0324803.

Mirizio, G; Sampson, S; Iwafuchi, M. Interplay between pioneer transcription factors and epigenetic modifiers in cell reprogramming. Regenerative Therapy. 2025; 28:246-252.

Mongan, M; Xiao, B; Christianto, A; Hu, YC; Xia, Y. Mitogen-Activated Protein Kinase Kinase Kinase 1 Overexpression Disrupts Development of the Ocular Surface Epithelium. Cells. 2025; 14:894.

Nunley, H; Xue, X; Fu, J; Lubensky, DK. Generation of fate patterns via intercellular forces. Physical Review Research. 2025; 7:l022051.

Peter, J; Caldwell, KC N; McClain, L; Tchieu, J; Ross, AE; Luo, Y. Inhibition of PTPRS function does not affect the survival or regeneration of dopaminergic neurons but alters synaptic function in the nigrostriatal pathway. Neurobiology of Disease. 2025; 213:107023.

Rui, TY; Huang, HZ; Zheng, K; Fan, HW; Zhang, J; Guo, ZY; Man, HY; Brazhe, N; Semyanov, A; Lu, YM; Liu, D; Zhu, LQ. Tau Pathology Drives Disease-Associated Astrocyte Reactivity in Salt-Induced Neurodegeneration. Advanced Science. 2025; 12:e2410799.

Setayesh, T; Chi, M; Oestreicher, Z; Sakabe, M; Seu, K; Zhu, Z; Kaur, H; Tijani, A; Xin, M; Shova, A; Balla, J; VandenHeuvel, K; Hu, YC; Malik, P. A novel mouse model of hemoglobin SC disease reveals mechanisms underlying beneficial effects of hydroxyurea. Blood. 2025; 146:13-28.

Shi, M; Crouse, B; Sundaram, N; Pode Shakked, N; Thorner, K; King, NM; Dutta, P; Ester, L; Zhang, W; Govindarajah, V; Mayhew, CN; Helmrath, MA; Bonventre, JV; McCracken, KW. Integrating collecting systems in human kidney organoids through fusion of distal nephron to ureteric bud. Cell Stem Cell. 2025; 32:1055-1070.e8.

Tominaga, K; Kechele, DO; Sanchez, JG; Vales, S; Jurickova, I; Roman, L; Asai, A; Enriquez, JR; McCauley, HA; Kishimoto, K; Zorn, AM; Helmrath, MA; Denson, LA; Wells, JM. Deriving Human Intestinal Organoids with Functional Tissue-Resident Macrophages All From Pluripotent Stem Cells. CMGH Cellular and Molecular Gastroenterology and Hepatology. 2025; 19:101444.

Tweedie, L; Riccetti, MR; Cain, B; Qin, S; Salomone, J; Webb, JA; Riesenberg, A; Ehrman, LA; Waclaw, RR; Kovall, RA; Gebelein, B; Campbell, K. Modelling a pathological GSX2 variant that selectively alters DNA binding reveals hypomorphic mouse brain defects. DMM Disease Models and Mechanisms. 2025; 18:dmm052110.

Xue, X; Liu, Y; Fu, J. Bioengineering embryo models. 2025; 3:11-29.

Zhang, J; Yang, CQ; Liu, ZQ; Wu, SP; Li, ZG; Zhang, LM; Fan, HW; Guo, ZY; Man, HY; Li, X; Lu, YM; Zhu, LQ; Liu, D. Cpeb1 remodels cell type-specific translational program to promote fear extinction. Science Advances. 2025; 11:eadr8687.