Endocrinology Research

Publications

Addison, J; Razzaghi, H; Bailey, C; Dickinson, K; Corathers, SD; Hartley, DM; Utidjian, L; Carle, AC; Rhodes, ET; Alonso, GT; et al. Testing an Automated Approach to Identify Variation in Outcomes among Children with Type 1 Diabetes across Multiple Sites. Pediatric Quality and Safety. 2022; 7.

Alexandrou, E; Corathers, S; Gutmark-Little, I; Casnellie, L; Gerstle, M; Tatum, J; Khoury, J; Backeljauw, P. Improving Anxiety Screening in Patients with Turner Syndrome. Hormone Research in Paediatrics. 2022; 95:68-75.

Alexandrou, E; Dauber, A; Tyzinski, L; Hwa, V; Andrew, M; Kim, H; Elangovan, S; Gubanich, P; Taylor-Haas, JA; Paterno, M; et al. Clinical phenotype and musculoskeletal characteristics of patients with aggrecan deficiency. American Journal of Medical Genetics, Part A. 2022; 188:1193-1203.

Allen, DB; Merchant, N; Miller, BS; Backeljauw, PF. Evolution and Future of Growth Plate Therapeutics. Hormone Research in Paediatrics. 2022; 94:319-332.

Backeljauw, P; Kanumakala, S; Loche, S; Schwab, KO; Miller, BS; Levy, R; McCormick, K; Zouater, H; Zabransky, M; Campbell, K. Safety and effectiveness of Omnitrope® (somatropin) in PATRO Children: a multi-center, post-marketing surveillance study comparison of US and international cohort data. European Journal of Pediatrics. 2022; 181:2367-2378.

Backeljauw, PF; Gutmark-Little, I; Little, K; Huron, A. OR18-6 Tracking the Diagnosis and Progression of Madelung Deformity in Pediatric Turner Syndrome Patients. Journal of the Endocrine Society. 2022; 6:a619-a619.

Bedi, S; Morris, J; Shah, A; Hart, RC; Gray Jerome, W; Aller, SG; Tang, C; Vaisar, T; Bornfeldt, KE; Segrest, JP; et al. Conformational flexibility of apolipoprotein A-I amino- and carboxy-termini is necessary for lipid binding but not cholesterol efflux. Journal of Lipid Research. 2022; 63.

Berlin, JA; Rubenfeld, GD; O'Cearbhaill, RE; Shah, AS; Fihn, SD. Keeping Meta-analyses Fresh. JAMA Network Open. 2022; 5.

Butler, MG; Miller, BS; Romano, A; Ross, J; Abuzzahab, MJ; Backeljauw, P; Bamba, V; Bhangoo, A; Mauras, N; Geffner, M. Genetic conditions of short stature: A review of three classic examples. Frontiers in Endocrinology. 2022; 13.

Cottrell, E; Andrews, A; Williams, J; Chatterjee, S; Edate, S; Metherell, LA; Hwa, V; Storr, HL. A rare heterozygous IGFI variant impairing IGF-I cleavage and causing postnatal growth failure: a novel disease mechanism offering insights into IGF-I physiology. 2022.

Cottrell, E; Maharaj, A; Triggs-Raine, B; Thanasupawat, T; Williams, J; Fujimoto, M; A., VD H; De, BC; Joustra, S; Kant, S; et al. Characterisation of the first heterozygous missense HMGA2 variant helps delineate the crucial functional roles of a novel growth gene. 2022.

Cottrell, E; Maharaj, A; Williams, J; Chatterjee, S; Cirillo, G; Miraglia Del Giudice, E; Festa, A; Palumbo, S; Capalbo, D; Salerno, M; et al. Growth Hormone Receptor (Ghr) 6ω Pseudoexon Activation: A Novel Cause Of Severe Growth Hormone Insensitivity (Ghi). Journal of Clinical Endocrinology and Metabolism. 2022.

Damen, MS M A; Alarcon, PC; Shah, AS; Divanovic, S. Greasing the inflammatory pathogenesis of viral pneumonias in diabetes. Obesity Reviews. 2022; 23.

Davidson, WS; Shah, AS; Sexmith, H; Gordon, SM. The HDL Proteome Watch: Compilation of studies leads to new insights on HDL function. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 2022; 1867.

Dowlut-McElroy, T; Davis, S; Howell, S; Gutmark-Little, I; Bamba, V; Prakash, S; Patel, S; Fadoju, D; Vijayakanthi, N; Haag, M; et al. Cell-free DNA screening positive for monosomy X: clinical evaluation and management of suspected maternal or fetal Turner syndrome. American Journal of Obstetrics and Gynecology. 2022; 227:862-870.

Eicher, AK; Kechele, DO; Sundaram, N; Berns, HM; Poling, HM; Haines, LE; Sanchez, JG; Kishimoto, K; Krishnamurthy, M; Han, L; et al. Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells. Cell Stem Cell. 2022; 29:36-51.e6.

Gutmark, E; Anand, V; Wheeler, A; Zahn, A; Cavari, Y; Eluk, T; Hay, M; Katoshevski, D; Gutmark-Little, I. Demonstration of mucus simulant clearance in a Bench-Model using acoustic Field-Integrated Intrapulmonary Percussive ventilation. Journal of Biomechanics. 2022; 144.

Honka, H; Chuang, J; D'Alessio, D; Salehi, M. Utility of Continuous Glucose Monitoring vs Meal Study in Detecting Hypoglycemia After Gastric Bypass. Journal of Clinical Endocrinology and Metabolism. 2022; 107:e2095-e2102.

Igudesman, D; Reboussin, BA; Souris, KJ; Pihoker, C; Dolan, L; Lawrence, JM; Saydah, S; Dabelea, D; Marcovina, S; Clouet-Foraison, N; et al. Trends in Glycemia between 2002 and 2016 among Incident Youth Cohorts Early in the Course of Type 1 Diabetes: The SEARCH for Diabetes in Youth Study. Journal of Diabetes Research. 2022; 2022.

Juul, A; Backeljauw, P; Cappa, M; Pietropoli, A; Kelepouris, N; Linglart, A; Pfäffle, R; Geffner, M. Early Growth Hormone Initiation Leads to Favorable Long-Term Growth Outcomes in Children Born Small for Gestational Age. Journal of Clinical Endocrinology and Metabolism. 2022.

Juul, A; Backeljauw, P; Højby, M; Kawai, M; Kildemoes, RJ; Linglart, A; Zuckerman-Levin, N; Horikawa, R. RF26 | PMON335 Once-Weekly Somapacitan Versus Daily Growth Hormone in Children Born Small for Gestational Age: Results From a Randomized Phase 2 Trial. Journal of the Endocrine Society. 2022; 6:a646-a646.

Kahkoska, AR; Pokaprakarn, T; Rumay Alexander, G; Crume, TL; Dabelea, D; Divers, J; Dolan, LM; Jensen, ET; Lawrence, JM; Marcovina, S; et al. The Impact of Racial and Ethnic Health Disparities in Diabetes Management on Clinical Outcomes: A Reinforcement Learning Analysis of Health Inequity Among Youth and Young Adults in the SEARCH for Diabetes in Youth Study. Diabetes Care. 2022; 45:108-118.

Kahkoska, AR; Sarteau, AC; Igudesman, D; Reboussin, BA; Dabelea, D; Dolan, LM; Jensen, E; Wadwa, RP; Pihoker, C; Mayer-Davis, EJ. Association of Insulin Regimen and Estimated Body Fat Over Time among Youths and Young Adults with Type 1 Diabetes: The SEARCH for Diabetes in Youth Study. Journal of Diabetes Research. 2022; 2022.

Kamoun, C; Khoury, JC; Beal, SJ; Crimmins, N; Corathers, SD. Opportunities for Enhanced Transition of Care Preparation for Adolescents and Emerging Adults With Type 1 Diabetes: Use of the READDY Transition Tool. Diabetes Spectrum. 2022; 35:57-65.

Kelsey, MM; Zeitler, PS; Nadeau, KJ; Shah, AS. Type 2 diabetes in youth: Rationale for use of off-label antidiabetic agents. Pediatric Diabetes. 2022; 23:615-619.

Kimura, M; Iguchi, T; Iwasawa, K; Dunn, A; Thompson, WL; Yoneyama, Y; Chaturvedi, P; Zorn, AM; Wintzinger, M; Quattrocelli, M; et al. En masse organoid phenotyping informs metabolic-associated genetic susceptibility to NASH. Cell. 2022; 185:4216-4232.e16.

Klepper, C; Crimmins, NA; Orkin, S; Sun, Q; Fei, L; Xanthakos, S; Mouzaki, M. Nonalcoholic Fatty Liver Disease in Young Children with Obesity. Childhood Obesity. 2022.

Krishnamurthy, M; Kechele, DO; Broda, T; Zhang, X; Enriquez, JR; McCauley, HA; Sanchez, JG; McCracken, K; Palermo, J; Bernieh, A; et al. Using Human Induced Pluripotent Stem Cell-Derived Organoids to Identify New Pathologies in Patients With PDX1 Mutations. Gastroenterology. 2022; 163:1053-1063.e7.

Krone, KA; Foley, CL; Fishman, MP; Vargas, SO; Forbes, LR; Vece, TJ; Al-Herz, W; Carey, B; Pai, SY; Hwa, V; et al. Signal Transducer and Activator of Transcription 5B Deficiency-associated Lung Disease. American Journal of Respiratory and Critical Care Medicine. 2022; 205:1245-1250.

Lavik, AR; Ebekozien, O; Noor, N; Alonso, GT; Polsky, S; Blackman, SM; Chen, J; Corathers, SD; Demeterco-Berggren, C; Gallagher, MP; et al. Trends in Type 1 Diabetic Ketoacidosis During COVID-19 Surges at 7 US Centers: Highest Burden on non-Hispanic Black Patients. Journal of Clinical Endocrinology and Metabolism. 2022; 107:1948-1955.

Lawson, SA; Hornung, LN; Lawrence, M; Schuler, CL; Courter, JD; Miller, C. An Initiative to Reduce Insulin-Related Adverse Drug Events in a Children's Hospital. Pediatrics. 2022; 149.

Limbert, C; Tinti, D; Malik, F; Kosteria, I; Messer, L; Jalaludin, YM; Benitez-Aguirre, P; Biester, S; Corathers, S; von Sengbusch, S; et al. ISPAD Clinical Practice Consensus Guidelines 2022: The delivery of ambulatory diabetes care to children and adolescents with diabetes. Pediatric Diabetes. 2022; 23:1243-1269.

Magge, SN; Wolf, RM; Pyle, L; Brown, EA; Benavides, VC; Bianco, ME; Chao, LC; Cymbaluk, A; Balikcioglu, PG; Halpin, K; et al. The Coronavirus Disease 2019 Pandemic is Associated with a Substantial Rise in Frequency and Severity of Presentation of Youth-Onset Type 2 Diabetes. Journal of Pediatrics. 2022; 251:51-59.e2.

Maharaj, A; Andrews, A; Chatterjee, S; Hwa, V; Storr, H. Defects in QSOX2, a novel regulator of STAT5B nuclear import and transcriptional activity, lead to severe post-natal growth restriction. 2022.

Maharaj, A; Cottrell, E; van, DH; de, BC; Joustra, S; Kant, S; van, dK D; Inmaculada, CD C L M; Massoud, A; Metherell, L; et al. Understanding the molecular basis of short stature in six patients with pathogenic variants in HMGA2. 2022.

Malik, FS; Sauder, KA; Isom, S; Reboussin, BA; Dabelea, D; Lawrence, JM; Roberts, A; Mayer-Davis, EJ; Marcovina, S; Dolan, L; et al. Trends in Glycemic Control Among Youth and Young Adults With Diabetes: The SEARCH for Diabetes in Youth Study. Diabetes Care. 2022; 45:285-294.

Marek-Yagel, D; Stenke, E; Pode-Shakked, B; Dunne, C; Crushell, E; Bryce-Smith, A; McDermott, M; O’Sullivan, MJ; Veber, A; Krishnamurthy, M; et al. Nonsense mutation in the novel PERCC1 gene as a genetic cause of congenital diarrhea and enteropathy. Human Genetics. 2022.

McCutcheon, E; Bowden, SA; Wasserman, H; Diaz-Thomas, A; Bijelic, V; Bachrach, LK; Robinson, ME. Treatment Practices and Confidence in the Management of Pediatric Metabolic Bone Disorders. Hormone Research in Paediatrics. 2022; 95:354-362.

Merjaneh, L; Dolan, LM; Suerken, CK; D'Agostino, R; Imperatore, G; Saydah, S; Roberts, A; Marcovina, S; Mayer-Davis, EJ; Dabelea, D; et al. A longitudinal assessment of diabetes autoantibodies in the SEARCH for diabetes in youth study. Pediatric Diabetes. 2022; 23:1027-1037.

Mukherjee, R; Sanchez-Gurmaches, J. Fluorescent Genetic Tools for Studying Brown Fat Development and Function in Mice. Methods in Molecular Biology. 2022; 2448:203-215.

Muthuvel, G; Dauber, A; Alexandrou, E; Tyzinski, L; Andrew, M; Hwa, V; Backeljauw, P. Treatment of Short Stature in Aggrecan-deficient Patients With Recombinant Human Growth Hormone: 1-Year Response. Journal of Clinical Endocrinology and Metabolism. 2022; 107:e2103-e2109.

Nagarajan, V; Juul, A; Backeljauw, P; Kawai, M; Linglart, A; Zuckerman-Levin, N; Horikawa, R. Abstract 102: Once-weekly somapacitan versus daily growth hormone in children born small for gestational age: 1-year results from a randomised phase 2 trial. Indian Journal of Endocrinology and Metabolism. 2022; 26.

Nasomyont, N; Meisman, AR; Ecklund, K; Vajapeyam, S; Cecil, KM; Tkach, JA; Altaye, M; Corathers, SD; Conard, LA; Kalkwarf, HJ; et al. Changes in Bone Marrow Adipose Tissue in Transgender and Gender Non-Conforming Youth Undergoing Pubertal Suppression: A Pilot Study. Journal of Clinical Densitometry. 2022; 25:485-489.

Newton, KP; Wilson, LA; Crimmins, NA; Fishbein, MH; Molleston, JP; Xanthakos, SA; Behling, C; Schwimmer, JB; Garner, D; Hertel, P; et al. Incidence of Type 2 Diabetes in Children With Nonalcoholic Fatty Liver Disease. Clinical Gastroenterology and Hepatology. 2022.

Oram, RA; Sharp, SA; Pihoker, C; Ferrat, L; Imperatore, G; Williams, A; Redondo, MJ; Wagenknecht, L; Dolan, LM; Lawrence, JM; et al. Utility of Diabetes Type-Specific Genetic Risk Scores for the Classification of Diabetes Type Among Multiethnic Youth. Diabetes Care. 2022; 45:1124-1131.

Pelham, SJ; Caldirola, MS; Avery, DT; Mackie, J; Rao, G; Gothe, F; Peters, TJ; Guerin, A; Neumann, D; Vokurkova, D; et al. STAT5B restrains human B-cell differentiation to maintain humoral immune homeostasis. Journal of Allergy and Clinical Immunology. 2022; 150:931-946.

Redel, JM; DiFrancesco, M; Lee, GR; Ziv, A; Dolan, LM; Brady, CC; Shah, AS. Cerebral blood flow is lower in youth with type 2 diabetes compared to obese controls: A pilot study. Pediatric Diabetes. 2022; 23:291-300.

Ross, JL; Fridman, M; Kelepouris, N; Murray, K; Krone, NP; Polak, M; Nedjatian, N; Rohrer, TR; Pietropoli, A; Lawrence, N; et al. LBMON197 Predictors Of Response To Growth Hormone Treatment In Pediatric Growth Disorders: Analysis From The Answer Program And Nordinet® IOS. Journal of the Endocrine Society. 2022; 6:a592-a592.

Schmidt, M; Lu, J; Luo, W; Cheng, L; Lee, M; Huang, R; Weng, Y; Kichler, JC; Corathers, SD; Jacobsen, LM; et al. Learning experience design of an mHealth self-management intervention for adolescents with type 1 diabetes. Educational Technology Research and Development. 2022; 70:2171-2209.

Segev, N; Arora, S; Khoury, J; Yayah Jones, NH; Chuang, J. Frequency and Severity of Hypothyroidism During TKI Therapy in the Pediatric and Young Adult Population. Journal of Pediatric Hematology/Oncology. 2022; 44:e964-e967.

Shah, AS; El ghormli, L; Gidding, SS; Hughan, KS; Levitt Katz, LE; Koren, D; Tryggestad, JB; Bacha, F; Braffett, BH; Arslanian, S; et al. Longitudinal changes in vascular stiffness and heart rate variability among young adults with youth-onset type 2 diabetes: results from the follow-up observational treatment options for type 2 diabetes in adolescents and youth (TODAY) study. Acta Diabetologica. 2022; 59:197-205.

Shah, AS; Gidding, SS; El ghormli, L; Tryggestad, JB; Nadeau, KJ; Bacha, F; Levitt Katz, LE; Willi, SM; Lima, J; Urbina, EM. Relationship between Arterial Stiffness and Subsequent Cardiac Structure and Function in Young Adults with Youth-Onset Type 2 Diabetes: Results from the TODAY Study. Journal of the American Society of Echocardiography. 2022; 35:620-628.e4.

Shah, AS; Isom, S; D’Agostino, R; Dolan, LM; Dabelea, D; Imperatore, G; Mottl, A; Lustigova, E; Pihoker, C; Marcovina, S; et al. Longitudinal Changes in Arterial Stiffness and Heart Rate Variability in Youth-Onset Type 1 Versus Type 2 Diabetes: The SEARCH for Diabetes in Youth Study. Diabetes Care. 2022; 45:1647-1656.

Shah, AS; Nadeau, KJ; Dabelea, D; Redondo, MJ. Spectrum of Phenotypes and Causes of Type 2 Diabetes in Children. Annual Review of Medicine. 2022; 73:501-515.

Shah, AS; Nadeau, KJ; Kelsey, MM. Broader Screening for Youth-Onset Type 2 Diabetes-We Just Are Not There Yet. JAMA Network Open. 2022; 5.

Shah, AS; Sadayappan, S; Urbina, EM. Lipids: a Potential Molecular Pathway Towards Diastolic Dysfunction in Youth-Onset Type 2 Diabetes. Current Atherosclerosis Reports. 2022; 24:109-117.

Shah, AS; Zeitler, PS; Wong, J; Pena, AS; Wicklow, B; Arslanian, S; Chang, N; Fu, J; Dabadghao, P; Pinhas-Hamiel, O; et al. ISPAD Clinical Practice Consensus Guidelines 2022: Type 2 diabetes in children and adolescents. Pediatric Diabetes. 2022; 23:872-902.

Suorsa-Johnson, KI; Gardner, MD; Baskin, A; Gruppen, LD; Rose, A; Rutter, MM; Schafer-Kalkhoff, T; Stacey, D; van Leeuwen, KD; Weidler, EM; et al. Defining successful outcomes and preferences for clinical management in differences/disorders of sex development: Protocol overview and a qualitative phenomenological study of stakeholders' perspectives. Journal of Pediatric Urology. 2022; 18:36.e1-36.e17.

Swauger, S; Sabulski, A; Hornung, L; Wasserman, H; Myers, KC; Howell, JC. Bone Health Outcomes at 1 Year after Hematopoietic Stem Cell Transplantation in a Heterogeneous Pediatric Population. Transplantation and cellular therapy. 2022; 28:44.e1-44.e6.

Swauger, SE; Hornung, LN; Elder, DA; Balamurugan, AN; Vitale, DS; Lin, TK; Nathan, JD; Abu-El-Haija, M. Predictors of Glycemic Outcomes at 1 Year Following Pediatric Total Pancreatectomy With Islet Autotransplantation. Diabetes Care. 2022; 45:295-302.

Tilden, DR; French, B; Shoemaker, AH; Corathers, S; Jaser, SS. Prolonged lapses between pediatric and adult care are associated with rise in HbA1c and inpatient days among patients with type 1 diabetes. Diabetes Research and Clinical Practice. 2022; 192.

Van Name, MA; Kanapka, LG; DiMeglio, LA; Miller, KM; Albanese-O’Neill, A; Commissariat, P; Corathers, SD; Harrington, KR; Hilliard, ME; Anderson, BJ; et al. Long-term Continuous Glucose Monitor Use in Very Young Children With Type 1 Diabetes: One-Year Results From the SENCE Study. Journal of diabetes science and technology. 2022.

Wenderfer, SE; Chang, JC; Davies, AG; Luna, IY; Scobell, R; Sears, C; Magella, B; Mitsnefes, M; Stotter, BR; Dharnidharka, VR; et al. Using a Multi-Institutional Pediatric Learning Health System to Identify Systemic Lupus Erythematosus and Lupus Nephritis: Development and Validation of Computable Phenotypes. Clinical journal of the American Society of Nephrology : CJASN. 2022; 17:65-74.

Whitacre, BE; Howles, P; Street, S; Morris, J; Swertfeger, D; Davidson, WS. Apolipoprotein E content of VLDL limits LPL-mediated triglyceride hydrolysis. Journal of Lipid Research. 2022; 63.

Williams, L; Baker-Smith, CM; Bolick, J; Carter, J; Kirkpatrick, C; Ley, SL; Peterson, AL; Shah, AS; Sikand, G; Ware, AL; et al. Nutrition interventions for youth with dyslipidemia: a National Lipid Association clinical perspective. Journal of Clinical Lipidology. 2022; 16:776-796.

Wiromrat, P; Namphaisan, P; Wongsurawat, N; Panamonta, O; Nasomyont, N. Elevated bone turnover markers predict bone mineral density accrual in adolescents with 21-hydroxylase deficiency. Clinical Endocrinology. 2022.

Wolf, RM; Noor, N; Izquierdo, R; Jett, D; Rewers, A; Majidi, S; Sheanon, N; Breidbart, E; Demeterco-Berggren, C; Lee, JM; et al. Increase in newly diagnosed type 1 diabetes in youth during the COVID-19 pandemic in the United States: A multi-center analysis. Pediatric Diabetes. 2022; 23:433-438.

Yeung, AM; Huang, J; Klonoff, DC; Seigel, RE; Goldman, JM; Shah, SN; Corathers, SD; Vidmar, AP; Tut, M; Espinoza, JC. iCoDE June 22, 2022 Steering Committee Meeting Summary Report. Journal of diabetes science and technology. 2022; 16:1575-1576.

Zhang, Y; Murakami, K; Borra, VJ; Ozen, MO; Demirci, U; Nakamura, T; Esfandiari, L. A Label-Free Electrical Impedance Spectroscopy for Detection of Clusters of Extracellular Vesicles Based on Their Unique Dielectric Properties. Biosensors. 2022; 12.