CYCLOPS reveals human transcriptional rhythms in health and disease. Proceedings of the National Academy of Sciences of the United States of America. 2017; 114:5312-5317..
Circadian Rhythms: Move Over Neurons - Astrocytes Mediate SCN Clock Function. Current Biology. 2017; 27:R350-R352..
Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism. Cell Metabolism. 2017; 25:961-974.e4..
MetaCycle: an integrated R package to evaluate periodicity in large scale data. Computer Applications in the Biosciences. 2016; 32:3351-3353..
Discovering Biology in Periodic Data through Phase Set Enrichment Analysis (PSEA). Journal of Biological Rhythms. 2016; 31:244-257..
KPNB1 mediates PER/CRY nuclear translocation and circadian clock function. eLife. 2015; 4..
Assessing the prevalence of mycoplasma contamination in cell culture via a survey of NCBI's RNA-seq archive. Nucleic Acids Research. 2015; 43:2535-2542..
A circadian gene expression atlas in mammals: implications for biology and medicine. Proceedings of the National Academy of Sciences of the United States of America. 2014; 111:16219-16224..
IVT-seq reveals extreme bias in RNA sequencing. Genome Biology. 2014; 15..
Machine learning helps identify CHRONO as a circadian clock component. PLoS Biology. 2014; 12..
A functional genomics screen for microRNA regulators of NF-kappaB signaling. BMC Biology. 2013; 11..
CircaDB: a database of mammalian circadian gene expression profiles. Nucleic Acids Research. 2013; 41:D1009-D1013..
Network dynamics to evaluate performance of an academic institution. Science Translational Medicine. 2010; 2..
JTK_CYCLE: an efficient nonparametric algorithm for detecting rhythmic components in genome-scale data sets. Journal of Biological Rhythms. 2010; 25:372-380..
The Gene Wiki: community intelligence applied to human gene annotation. Nucleic Acids Research. 2010; 38:D633-D639..
A genome-wide RNAi screen for modifiers of the circadian clock in human cells. Cell. 2009; 139:199-210..
Harmonics of circadian gene transcription in mammals. PLoS Genetics. 2009; 5..
ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing. Molecular Cell. 2009; 33:591-601..
Network features of the mammalian circadian clock. PLoS Biology. 2009; 7..
WAVECLOCK: wavelet analysis of circadian oscillation. Computer Applications in the Biosciences. 2008; 24:2794-2795..
Power-law-like distributions in biomedical publications and research funding. Genome Biology. 2007; 8..
Feedback repression is required for mammalian circadian clock function. Nature Genetics. 2006; 38:312-319..
A strategy for probing the function of noncoding RNAs finds a repressor of NFAT. Science. 2005; 309:1570-1573..
BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis. PLoS Biology. 2004; 2..
A functional genomics strategy reveals Rora as a component of the mammalian circadian clock. Neuron. 2004; 43:527-537..
A gene atlas of the mouse and human protein-encoding transcriptomes. Proceedings of the National Academy of Sciences of the United States of America. 2004; 101:6062-6067..
TORCs: transducers of regulated CREB activity. Molecular Cell. 2003; 12:413-423..
Melanopsin is required for non-image-forming photic responses in blind mice. Science. 2003; 301:525-527..
A heat-sensitive TRP channel expressed in keratinocytes. Science. 2002; 296:2046-2049..
Coordinated transcription of key pathways in the mouse by the circadian clock. Cell. 2002; 109:307-320..
Large-scale analysis of the human and mouse transcriptomes. Proceedings of the National Academy of Sciences of the United States of America. 2002; 99:4465-4470..
A comparison of the Celera and Ensembl predicted gene sets reveals little overlap in novel genes. Cell. 2001; 106:413-415..
Mop3 is an essential component of the master circadian pacemaker in mammals. Cell. 2000; 103:1009-1017..
The basic helix-loop-helix-PAS protein MOP9 is a brain-specific heterodimeric partner of circadian and hypoxia factors. Journal of Neuroscience. 2000; 20..
Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway. Journal of Biological Chemistry. 1997; 272:8581-8593..
Toward Precision Medicine: Circadian Rhythm of Blood Pressure and Chronotherapy for Hypertension - 2021 NHLBI Workshop Report. Hypertension. 2023; 80:503-522..
2023; 68.. Go to bed!: Sleep as a risk factor for adolescent hypertension. Progress in Pediatric Cardiology.
Daytime-restricted parenteral feeding is associated with earlier oral intake in children following stem cell transplant. Journal of Clinical Investigation. 2023; 133..
Integration of genome-scale data identifies candidate sleep regulators. Sleep. 2023; 46..
2023; 29.. 167 Earlier Oral Intake in Pediatric Stem Cell Transplant Patients Receiving Time-Restricted Feeding: A Prospective, Randomized Trial. Transplantation and cellular therapy.
Ontogeny and function of the circadian clock in intestinal organoids. EMBO Journal. 2022; 41..
An in silico genome-wide screen for circadian clock strength in human samples. Computer Applications in the Biosciences. 2022; 38:5375-5382..
2022; 100:s46-s47.. Developing a Multidisciplinary Pediatric Circadian Medicine Clinic: The Circadian and Complex Sleep Disorders Clinic. Sleep Medicine.
2022; 100:s51-s52.. Outcomes of Pre-treatment and Post-treatment measures after therapy for pediatric circadian disorders. Sleep Medicine.
2022; 100.. Suvorexant Is Safe and Effective in a Pediatric Population: A Single-Center, Retrospective Study. Sleep Medicine.
2022; 100:s172-s173.. Safe and Effective Use of Suvorexant in Children with Neurodevelopmental Disorders: A Single-Center, Retrospective Study of Clinical Practice. Sleep Medicine.
Diurnal rhythms of spontaneous intracranial high-frequency oscillations. Seizure : the journal of the British Epilepsy Association. 2022; 102:105-112..
duper is a null mutation of Cryptochrome 1 in Syrian hamsters. Proceedings of the National Academy of Sciences of the United States of America. 2022; 119..
Analysis of Diurnal Variations in Heart Rate: Potential Applications for Chronobiology and Cardiovascular Medicine. Frontiers in Physiology. 2022; 13..
Normalized coefficient of variation (nCV): a method to evaluate circadian clock robustness in population scale data. Computer Applications in the Biosciences. 2021; 37:4581-4583..
CAMPAREE: a robust and configurable RNA expression simulator. BMC Genomics. 2021; 22..
NF-κB modifies the mammalian circadian clock through interaction with the core clock protein BMAL1. PLoS Genetics. 2021; 17..
The Circadian Clock Gene, Bmal1, Regulates Intestinal Stem Cell Signaling and Represses Tumor Initiation. CMGH Cellular and Molecular Gastroenterology and Hepatology. 2021; 12:1847-1872.e0..
Lowering Nighttime Blood Pressure With Bedtime Dosing of Antihypertensive Medications: Controversies in Hypertension - Con Side of the Argument. Hypertension. 2021; 78:871-878..
Response to Lowering Nighttime Blood Pressure with Bedtime Dosing of Antihypertensive Medications: Controversies in Hypertension - Pro Side of the Argument. Hypertension. 2021; 78..
Short-term exposure to intermittent hypoxia leads to changes in gene expression seen in chronic pulmonary disease. eLife. 2021; 10..
CRY1-CBS binding regulates circadian clock function and metabolism. FEBS Journal. 2021; 288:614-639..
The central melanocortin system mediates the benefits of time-restricted feeding on energy balance. Physiology and Behavior. 2020; 227..
A population-based gene expression signature of molecular clock phase from a single epidermal sample. Genome Medicine. 2020; 12..
2020; 6:92-105.. Genome-wide studies of time of day in the brain: Design and analysis.
Adaptive Thermogenesis in Mice Is Enhanced by Opsin 3-Dependent Adipocyte Light Sensing. Cell Reports. 2020; 30:672-686.e8..
When Should You Take Your Medicines?. Journal of Biological Rhythms. 2019; 34:582-583..
The NRON complex controls circadian clock function through regulated PER and CRY nuclear translocation. Scientific Reports. 2019; 9..
A large-scale study reveals 24-h operational rhythms in hospital treatment. Proceedings of the National Academy of Sciences of the United States of America. 2019; 116:20953-20958..
Dosing time matters. Science. 2019; 365:547-549..
Medicine in the Fourth Dimension. Cell Metabolism. 2019; 30:238-250..
Sleep and Circadian Medicine: Time of Day in the Neurologic Clinic. Neurologic Clinics. 2019; 37:615-629..
Reply to Furlan et al.: The role of SIRT1 in cell autonomous clock function. Proceedings of the National Academy of Sciences of the United States of America. 2019; 116..
Genome-wide effect of pulmonary airway epithelial cell-specific Bmal1 deletion. FASEB Journal. 2019; 33:6226-6238..
Shift Work Disrupts Circadian Regulation of the Transcriptome in Hospital Nurses. Journal of Biological Rhythms. 2019; 34:167-177..
Polycystin-1 regulates bone development through an interaction with the transcriptional coactivator TAZ. Human Molecular Genetics. 2019; 28:16-30..