Wallach, I; Bernard, D; Nguyen, K; Ho, G; Morrison, A; Stecula, A; Rosnik, A; O’Sullivan, AM; Davtyan, A; Samudio, B; Lam, A; Cuddihy, AR; White, A; Taglialatela, A. AI is a viable alternative to high throughput screening: a 318-target study. Scientific Reports. 2024; 14:7526.

Rudman-Melnick, V; Vanhoutte, D; Stowers, K; Sargent, M; Adam, M; Ma, Q; Perl, AK T; Miethke, AG; Burg, A; Shi, T; Hildeman, DA; Woodle, ES S; Kofron, JM; Devarajan, P. Gucy1α1 specifically marks kidney, heart, lung and liver fibroblasts. Scientific Reports. 2024; 14:29307.

Fava, A; Wagner, CA; Guthridge, CJ; Kheir, J; Macwana, S; DeJager, W; Gross, T; Izmirly, P; Belmont, HM; Diamond, B; Guthridge, JM; Petri, M; Buyon, J; James, JA. Association of Autoantibody Concentrations and Trajectories With Lupus Nephritis Histologic Features and Treatment Response. Arthritis and Rheumatology. 2024; 76:1611-1622.

Pundavela, J; Dinglasan, SA; Touvron, M; Hummel, SA; Hu, L; Rizvi, TA; Choi, K; Hildeman, DA; Ratner, N. Stimulator of interferon gene facilitates recruitment of effector CD8 T cells that drive neurofibromatosis type 1 nerve tumor initiation and maintenance. Science Advances. 2024; 10:eado6342.

Thorman, AW; Reigle, J; Chutipongtanate, S; Yang, J; Shamsaei, B; Pilarczyk, M; Fazel-Najafabadi, M; Adamczak, R; Kouril, M; Bhatnagar, S; Hildeman, DA; Medvedovic, M; Herr, AB; Meller, J. Accelerating drug discovery and repurposing by combining transcriptional signature connectivity with docking. Science Advances. 2024; 10:eadj3010.

Potter, A; Wikenheiser-Brokamp, K; Hildeman, D; Sharma, N; Gu, M; Patel, K; Qureshi, M; Khan, MM; Wallace, C; Ziady, A; Hayes, D. (601) Decoding T Cell Clonal Dynamics in Acute Lung Rejection. The Journal of Heart and Lung Transplantation. 2024; 43:s293.

Ochoa, TA; Rossi, A; Woodle, ES; Hildeman, D; Allman, D. The Proteasome Inhibitor Bortezomib Induces p53-Dependent Apoptosis in Activated B Cells. Journal of immunology (Baltimore, Md. : 1950). 2024; 212:154-164.

Khorki, ME; Shi, T; Cianciolo, EE; Burg, AR; Chukwuma, PC; Picarsic, JL; Morrice, MK; Woodle, ES; Maltzman, JS; Ferguson, A; Katz, JD; Baker, BM; Hildeman, DA. Prior viral infection primes cross-reactive CD8+ T cells that respond to mouse heart allografts. Frontiers in Immunology. 2023; 14:1287546.

Thomas, AL; Godarova, A; Wayman, JA; Miraldi, ER; Hildeman, DA; Chougnet, CA. Accumulation of immune-suppressive CD4 + T cells in aging - tempering inflammaging at the expense of immunity. Seminars in Immunology. 2023; 70:101836.

Mahajan, S; Alexander, A; Koenig, Z; Saba, N; Prasanphanich, N; Hildeman, DA; Chougnet, CA; DeFranco, E; Andorf, S; Tilburgs, T. Antigen-specific decidual CD8+ T cells include distinct effector memory and tissue-resident memory cells. JCI insight. 2023; 8:e171806.

Ware, J; Mcelhinney, K; Latham, T; Lane, A; Dienger-Stambaugh, K; Hildeman, D; Spearman, P; Ware, RE. Sustained and Boosted Antibody Responses in Breast Milk After Maternal SARS-CoV-2 Vaccination. Breastfeeding Medicine. 2023; 18:612-620.

Shi, T; Burg, AR; Caldwell, JT; Roskin, KM; Castro-Rojas, CM; Chukwuma, PC; Gray, GI; Foote, SG; Alonso, JA; Cuda, CM; Shields, AR; Baker, BM; Woodle, ES; Hildeman, DA. Single-cell transcriptomic analysis of renal allograft rejection reveals insights into intragraft TCR clonality. The Journal of Clinical Investigation. 2023; 133:e170191.

Rossi, AP; Tremblay, S; Castro-Rojas, CM; Burg, AA; Roskin, KM; Gehman, JM; Rike-Shields, A; Alloway, RR; Brailey, P; Allman, D; Hildeman, DA; Woodle, ES. Effects of invivo CXCR4 blockade and proteasome inhibition on bone marrow plasma cells in HLA-sensitized kidney transplant candidates. American Journal of Transplantation. 2023; 23:759-775.

Vitale, I; Pietrocola, F; Guilbaud, E; Aaronson, SA; Abrams, JM; Adam, D; Agostini, M; Agostinis, P; Alnemri, ES; Altucci, L; Janic, A; Joseph, B; Jost, PJ; Kanneganti, TD. Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell Death and Differentiation. 2023; 30:1097-1154.

Peters, AL; Rogers, M; Begum, G; Sun, Q; Fei, L; Leino, D; Hildeman, D; Woodle, ES. T-cell infiltrate intensity is associated with delayed response to treatment in late acute cellular rejection in pediatric liver transplant recipients. Pediatric Transplantation. 2023; 27:e14475.

Shi, T; Malik, A; vom Hofe, AY; Matuschek, L; Mullen, M; Lages, CS; Kudira, R; Singh, R; Zhang, W; Setchell, KD R; Hildeman, D; Pasare, C; Wagner, B; Miethke, AG. Farnesoid X receptor antagonizes macrophage-dependent licensing of effector T lymphocytes and progression of sclerosing cholangitis. Science Translational Medicine. 2022; 14:eabi4354.

Thomas, AL; Lehn, MA; Janssen, EM; Hildeman, DA; Chougnet, CA. Naturally-aged microglia exhibit phagocytic dysfunction accompanied by gene expression changes reflective of underlying neurologic disease. Scientific Reports. 2022; 12:19471.

Carlucci, PM; Li, J; Fava, A; Deonaraine, KK; Wofsy, D; James, JA; Putterman, C; Diamond, B; Davidson, A; Fine, DM; Filer, A; Raza, K; Sahbudin, I; Pitzalis, C. High incidence of proliferative and membranous nephritis in SLE patients with low proteinuria in the Accelerating Medicines Partnership. Rheumatology. 2022; 61:4335-4343.

Korinfskaya, S; Kotliar, M; Katko, A; Hildeman, D; Miraldi, ER; Barski, A. Role of transcription factor RUNX1 in the maintenance of T helper cell epigenome and rapid recall response. Journal of immunology (Baltimore, Md. : 1950). 2022; 208:56.13.

Shanmuganad, S; Hummel, SA; Varghese, V; Hildeman, DA. Bcl-2 Is Necessary to Counteract Bim and Promote Survival of TCRαβ+CD8αα+ Intraepithelial Lymphocyte Precursors in the Thymus. Journal of immunology (Baltimore, Md. : 1950). 2022; 208:651-659.

Shi, T; Roskin, K; Baker, BM; Woodle, ES; Hildeman, D. Advanced Genomics-Based Approaches for Defining Allograft Rejection With Single Cell Resolution. Frontiers in Immunology. 2021; 12:750754.

Thomas, AL; Alarcon, PC; Divanovic, S; Chougnet, CA; Hildeman, DA; Moreno-Fernandez, ME. Implications of Inflammatory States on Dysfunctional Immune Responses in Aging and Obesity. Frontiers in Aging. 2021; 2:732414.

Rossi, AP; Alloway, RR; Hildeman, D; Woodle, ES. Plasma cell biology: Foundations for targeted therapeutic development in transplantation. Immunological Reviews. 2021; 303:168-186.

Davis, G; York, AJ; Bacon, WC; Lin, SC; McNeal, MM; Yarawsky, AE; Maciag, JJ; Miller, JL C; Locker, KC S; Bailey, M; Jordan, MB; Herr, AB; Hildeman, DA; Molkentin, JD. Seroprevalence of SARS-CoV-2 infection in Cincinnati Ohio USA from August to December 2020. Editor, Kumar B. PloS one. 2021; 16:e0254667.

Moreno-Fernandez, ME; Sharma, V; Stankiewicz, TE; Oates, JR; Doll, JR; Damen, MS M A; Almanan, MA T A; Chougnet, CA; Hildeman, DA; Divanovic, S. Aging mitigates the severity of obesity-associated metabolic sequelae in a gender independent manner. Nutrition and Diabetes. 2021; 11:15.

Kirk, AD; Adams, AB; Durrbach, A; Ford, ML; Hildeman, DA; Larsen, CP; Vincenti, F; Wojciechowski, D; Woodle, ES. Optimization of de novo belatacept-based immunosuppression administered to renal transplant recipients. American Journal of Transplantation. 2021; 21:1691-1698.

Newton, HS; Gawali, VS; Chimote, AA; Lehn, MA; Palackdharry, SM; Hinrichs, BH; Jandarov, R; Hildeman, D; Janssen, EM; Wise-Draper, TM; Conforti, L. PD1 blockade enhances K+ channel activity, Ca2+ signaling, and migratory ability in cytotoxic T lymphocytes of patients with head and neck cancer. Journal for ImmunoTherapy of Cancer. 2020; 8:e000844.

Almanan, M; Raynor, J; Ogunsulire, I; Malyshkina, A; Mukherjee, S; Hummel, SA; Ingram, JT; Saini, A; Xie, MM; Alenghat, T; Dent, AL; Holscher, C; Chougnet, C; Hildeman, DA. IL-10-producing Tfh cells accumulate with age and link inflammation with age-related immune suppression. Science Advances. 2020; 6:eabb0806.

Woodle, ES; Tremblay, S; Rossi, A; Rojas, CC; Alloway, R; Roskin, K; Allman, D; Hildeman, D. Plasma cell targeting to prevent antibody-mediated rejection. American Journal of Transplantation. 2020; 20 Suppl 4:33-41.

Newton, H; Gawali, VS; Chimote, AA; Lehn, M; Palackdharry, S; Hildeman, D; Janssen, E; Wise-Draper, T; Conforti, L. Pembrolizumab treatment increases K+ channel function and calcium fluxes in cytotoxic T cells of head and neck cancer patients. Journal of immunology (Baltimore, Md. : 1950). 2020; 204:165.41.

Castro-Rojas, CM; Godarova, A; Shi, T; Hummel, SA; Shields, A; Tremblay, S; Alloway, RR; Jordan, MB; Woodle, ES; Hildeman, DA. mTOR Inhibitor Therapy Diminishes Circulating CD8+ CD28- Effector Memory T Cells and Improves Allograft Inflammation in Belatacept-refractory Renal Allograft Rejection. Transplantation. 2020; 104:1058-1069.

Li, K; Ladle, BH; Kurtulus, S; Sholl, A; Shanmuganad, S; Hildeman, DA. T-cell receptor signal strength and epigenetic control of Bim predict memory CD8+ T-cell fate. Cell Death and Differentiation. 2020; 27:1214-1224.

Raynor, J; Lin, A; Hummel, SA; Lampe, K; Jordan, M; Hoebe, K; Hildeman, DA. The Variable Genomic NK Cell Receptor Locus Is a Key Determinant of CD4+ T Cell Responses During Viral Infection. Frontiers in Immunology. 2020; 11:197.

Tremblay, S; Driscoll, JJ; Rike-Shields, A; Hildeman, DA; Alloway, RR; Girnita, AL; Brailey, PA; Woodle, ES. A prospective, iterative, adaptive trial of carfilzomib-based desensitization. American Journal of Transplantation. 2020; 20:411-421.