Immunobiology

Alarcon, PC; Damen, MS M A; Madan, R; Deepe, GS; Spearman, P; Way, SS; Divanovic, S. Adipocyte inflammation and pathogenesis of viral pneumonias: an overlooked contribution. Mucosal Immunology. 2021.

Chandra, S; Chandrakasan, S; Dávila Saldaña, BJ; Bleesing, JJ; Jordan, MB; Kumar, AR; Grimley, MS; Krupski, C; Davies, SM; Khandelwal, P; et al. Experience with a Reduced Toxicity Allogeneic Transplant Regimen for Non-CGD Primary Immune Deficiencies Requiring Myeloablation. Journal of Clinical Immunology. 2021; 41:89-98.

Eshleman, EM; Alenghat, T. Epithelial sensing of microbiota-derived signals. Genes and Immunity. 2021.

Ferrell, J; Sharp, S; Kumar, A; Jordan, M; Picarsic, J; Nelson, A. Discrepancies between F-18-FDG PET/CT findings and conventional imaging in Langerhans cell histiocytosis. Pediatric Blood and Cancer. 2021; 68.

Gonzalez, T; Stevens, ML; Kyzy, AB; Alarcon, R; He, H; Kroner, JW; Spagna, D; Grashel, B; Sidler, E; Martin, LJ; et al. Biofilm propensity of Staphylococcus aureus skin isolates is associated with increased atopic dermatitis severity and barrier dysfunction in the MPAACH pediatric cohort. Allergy: European Journal of Allergy and Clinical Immunology. 2021; 76:302-313.

Hashimoto-Hill, S; Alenghat, T. Inflammation-Associated Microbiota Composition Across Domestic Animals. Frontiers in Genetics. 2021; 12.

Ho, JS Y; Mok, BW Y; Campisi, L; Jordan, T; Yildiz, S; Parameswaran, S; Wayman, JA; Gaudreault, NN; Meekins, DA; Indran, SV; et al. TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation. Cell. 2021; 184:2618-2632.e17.

Ikumi, NM; Pillay, K; Tilburgs, T; Malaba, TR; Dzanibe, S; Enninga, EA L; Chakraborty, R; Lamorde, M; Myer, L; Khoo, S; et al. T cell Homeostatic Imbalance in Placentae from Women with HIV in the absence of Vertical Transmission. Journal of Infectious Diseases. 2021.

Jose, S; Mukherjee, A; Horrigan, O; Setchell, KD R; Zhang, W; Moreno-Fernandez, ME; Andersen, H; Sharma, D; Haslam, DB; Divanovic, S; et al. Obeticholic acid ameliorates severity of Clostridioides difficile infection in high fat diet-induced obese mice. Mucosal Immunology. 2021; 14:500-510.

Khandelwal, P; Teusink-Cross, A; Kumar, AR; Bleesing, JJ; Mehta, PA; Jordan, MB; Chandra, S; Davies, SM; Marsh, RA. Daratumumab for the management of autoimmune cytopenias in children and young adults: a case series. British Journal of Haematology. 2021.

Khodoun, MV; Morris, SC; Shao, WH; Potter, C; Angerman, E; Kiselev, A; Yarawsky, AE; Herr, AB; Klausz, K; Otte, A; et al. Suppression of IgE-mediated anaphylaxis and food allergy with monovalent anti-FcεRIα mAbs. Journal of Allergy and Clinical Immunology. 2021; 147:1838-1854.e4.

Kirk, AD; Adams, AB; Durrbach, A; Ford, ML; Hildeman, DA; Larsen, CP; Vincenti, F; Wojciechowski, D; Woodle, ES. Optimization of de novo belatacept-based immunosuppression administered to renal transplant recipients. American Journal of Transplantation. 2021; 21:1691-1698.

Li, Q; Meissner, TB; Wang, F; Du, Z; Ma, S; Kshirsagar, S; Tilburgs, T; Buenrostro, JD; Uesugi, M; Strominger, JL. ELF3 activated by a superenhancer and an autoregulatory feedback loop is required for high-level HLA-C expression on extravillous trophoblasts. Proceedings of the National Academy of Sciences of the United States of America. 2021; 118.

Marsh, RA; Zoref-Lorenz, A; Owsley, E; Chaturvedi, V; Nguyen, TC; Goldman, JR; Henry, MM; Greenberg, JN; Ladisch, S; Hermiston, ML; et al. T-cell activation profiles distinguish hemophagocytic lymphohistiocytosis and early sepsis. Blood. 2021; 137:2337-2346.

Miraldi, ER; Chen, X; Weirauch, MT. Deciphering cis-regulatory grammar with deep learning. Nature Genetics. 2021; 53:266-268.

Moreno-Fernandez, ME; Giles, DA; Oates, JR; Chan, CC; Damen, MS M A; Doll, JR; Stankiewicz, TE; Chen, X; Chetal, K; Karns, R; et al. PKM2-dependent metabolic skewing of hepatic Th17 cells regulates pathogenesis of non-alcoholic fatty liver disease. Cell Metabolism. 2021; 33:1187-1204.e9.

Moreno-Fernandez, ME; Sharma, V; Stankiewicz, TE; Oates, JR; Doll, JR; Damen, MS M A; Almanan, MA T A; Chougnet, CA; Hildeman, DA; Divanovic, S. Aging mitigates the severity of obesity-associated metabolic sequelae in a gender independent manner. Nutrition and Diabetes. 2021; 11.

Noah, TK; Lee, JB; Brown, CA; Yamani, A; Tomar, S; Ganesan, V; Newberry, RD; Huffnagle, GB; Divanovic, S; Hogan, SP. Thermoneutrality Alters Gastrointestinal Antigen Passage Patterning and Predisposes to Oral Antigen Sensitization in Mice. Frontiers in Immunology. 2021; 12.

Serrano-Lopez, J; Hegde, S; Kumar, S; Serrano, J; Fang, J; Wellendorf, AM; Roche, PA; Rangel, Y; Carrington, LJ; Geiger, H; et al. Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics. eLife. 2021; 10.

Slater, A; Di, Y; Clark, JC; Jooss, NJ; Martin, EM; Alenazy, F; Thomas, MR; Ariëns, RA S; Herr, AB; Poulter, NS; et al. Structural characterization of a novel GPVI-nanobody complex reveals a biologically active domain-swapped GPVI dimer. Blood. 2021; 137:3443-3453.

Song, R; Gao, Y; Dozmorov, I; Malladi, V; Saha, I; McDaniel, MM; Parameswaran, S; Liang, C; Arana, C; Zhang, B; et al. IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility. Cell Reports. 2021; 34.

Tilburgs, T. Chapter 2 Presentation and recognition of placental, fetal, and pathogen-derived antigens in human pregnancy. Reproductive Immunology. 2021.

Ye, H; Minhajuddin, M; Krug, A; Pei, S; Chou, C; Culp-Hill, R; Ponder, J; De Bloois, E; Schniedewind, B; Amaya, ML; et al. The Hepatic Microenvironment Uniquely Protects Leukemia Cells through Induction of Growth and Survival Pathways Mediated by LIPG. Cancer Discovery. 2021; 11:500-519.

Zamakhaeva, S; Chaton, CT; Rush, JS; Ajay Castro, S; Kenner, CW; Yarawsky, AE; Herr, AB; van Sorge, NM; Dorfmueller, HC; Frolenkov, GI; et al. Modification of cell wall polysaccharide guides cell division in Streptococcus mutans. Nature Chemical Biology. 2021.

Zhang, J; Wu, Q; Johnson, CB; Pham, G; Kinder, JM; Olsson, A; Slaughter, A; May, M; Weinhaus, B; D’Alessandro, A; et al. In situ mapping identifies distinct vascular niches for myelopoiesis. Nature: New biology. 2021; 590:457-462.

Zoref-Lorenz, A; Jordan, MB. Challenges in improving global outcomes for hemophagocytic lymphohistiocytosis. Pediatric Hematology and Oncology. 2021; 38:191-193.