Publications

Antoniou, K; Ender, F; Vollbrandt, T; Laumonnier, Y; Rathmann, F; Pasare, C; Singh, H; Koehl, J. Allergen-Induced C5a/C5aR1 Axis Activation in Pulmonary CD11b(+) cDCs Promotes Pulmonary Tolerance through Downregulation of CD40. Cells. 2020; 9:300-300.

Boucher, AA; Rosenfeldt, L; Mureb, D; Shafer, J; Sharma, BK; Lane, A; Crowther, RR; McKell, MC; Whitt, J; Alenghat, T; et al. Cell type-specific mechanisms coupling protease-activated receptor-1 to infectious colitis pathogenesis. Journal of Thrombosis and Haemostasis. 2020; 18:91-103.

Castro-Rojas, CM; Godarova, A; Shi, T; Hummel, SA; Shields, A; Tremblay, S; Alloway, RR; Jordan, MB; Woodle, ES; Hildeman, DA. mTOR Inhibitor Therapy Diminishes Circulating CD8+ CD28- Effector Memory T Cells and Improves Allograft Inflammation in Belatacept-refractory Renal Allograft Rejection. Transplantation. 2020; 104:1058-1069.

Chan, AY; Leiding, JW; Liu, X; Logan, BR; Burroughs, LM; Allenspach, EJ; Skoda-Smith, S; Uzel, G; Notarangelo, LD; Slatter, M; et al. Hematopoietic Cell Transplantation in Patients With Primary Immune Regulatory Disorders (PIRD): A Primary Immune Deficiency Treatment Consortium (PIDTC) Survey. Frontiers in Immunology. 2020; 11.

Chan, CC; Damen, MS M A; Moreno-Fernandez, ME; Stankiewicz, TE; Cappelletti, M; Alarcon, PC; Oates, JR; Doll, JR; Mukherjee, R; Chen, X; et al. Type I interferon sensing unlocks dormant adipocyte inflammatory potential. Nature Communications. 2020; 11.

Doll, JR; Hoebe, K; Thompson, RL; Sawtell, NM. Resolution of herpes simplex virus reactivation in vivo results in neuronal destruction. PLoS Pathogens. 2020; 16:e1008296-e1008296.

Fisher, AL; Sangkhae, V; Presicce, P; Chougnet, CA; Jobe, AH; Kallapur, SG; Tabbah, S; Buhimschi, CS; Buhimschi, IA; Ganz, T; et al. Fetal and amniotic fluid iron homeostasis in healthy and complicated murine, macaque, and human pregnancy. JCI insight. 2020; 5.

Gao, Y; Deason, K; Jain, A; Irizarry-Caro, RA; Dozmorov, I; Coughlin, LA; Rauch, I; Evers, BM; Koh, AY; Wakeland, EK; et al. Transcriptional profiling identifies caspase-1 as a T cell–intrinsic regulator of Th17 differentiation. The Journal of Experimental Medicine. 2020; 217.

Hinge, A; He, J; Bartram, J; Javier, J; Xu, J; Fjellman, E; Sesaki, H; Li, T; Yu, J; Wunderlich, M; et al. Asymmetrically Segregated Mitochondria Provide Cellular Memory of Hematopoietic Stem Cell Replicative History and Drive HSC Attrition. Cell Stem Cell. 2020; 26:420-430.e6.

Ho, JS Y; Angel, M; Ma, Y; Sloan, E; Wang, G; Martinez-Romero, C; Alenquer, M; Roudko, V; Chung, L; Zheng, S; et al. Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection. Cell. 2020; 181:1502-1517.e23.

Jain, A; Irizarry-Caro, RA; McDaniel, MM; Chawla, AS; Carroll, KR; Overcast, GR; Philip, NH; Oberst, A; Chervonsky, AV; Katz, JD; et al. T cells instruct myeloid cells to produce inflammasome-independent IL-1β and cause autoimmunity. Nature Immunology. 2020; 21:69-74.

Jain, VG; Kong, F; Kallapur, SG; Presicce, P; Senthamaraikannnan, P; Cappelletti, M; Chougnet, CA; Bhattacharyya, S; Pasare, C; Muglia, LJ. IRAK1 is a critical mediator of inflammation-induced preterm birth. Journal of immunology (Baltimore, Md. : 1950). 2020; 204:2651-2660.

Khandelwal, P; Chaturvedi, V; Owsley, E; Lane, A; Heyenbruch, D; Lutzko, CM; Leemhuis, T; Grimley, MS; Nelson, AS; Davies, SM; et al. CD38brightCD8+ T Cells Associated with the Development of Acute GVHD Are Activated, Proliferating, and Cytotoxic Trafficking Cells. Biology of Blood and Marrow Transplantation. 2020; 26:1-6.

Khodoun, MV; Morris, SC; Angerman, E; Potter, C; Schuman, R; Wunderlich, M; Maciag, JJ; Locker, KC S; Mulloy, JC; Herr, AB; et al. Rapid desensitization of humanized mice with anti-human FcεRIα monoclonal antibodies. Journal of Allergy and Clinical Immunology. 2020; 145:907-921.e3.

Lee, PY; Kellner, ES; Huang, Y; Furutani, E; Huang, Z; Bainter, W; Alosaimi, MF; Stafstrom, K; Platt, CD; Stauber, T; et al. Genotype and functional correlates of disease phenotype in deficiency of adenosine deaminase 2 (DADA2). Journal of Allergy and Clinical Immunology. 2020; 145:1664-1672.e10.

Li, K; Ladle, BH; Kurtulus, S; Sholl, A; Shanmuganad, S; Hildeman, DA. T-cell receptor signal strength and epigenetic control of Bim predict memory CD8+ T-cell fate. Cell Death and Differentiation. 2020; 27:1214-1224.

Locatelli, F; Jordan, MB; Allen, C; Cesaro, S; Rizzari, C; Rao, A; Degar, B; Garrington, TP; Sevilla, J; Putti, M; et al. Emapalumab in children with primary hemophagocytic lymphohistiocytosis. The New England journal of medicine. 2020; 382:1811-1822.

Lucas, D; Salomonis, N; Grimes, HL. Unraveling bone marrow architecture. Nature Cell Biology. 2020; 22:5-6.

McDaniel, MM; Kottyan, LC; Singh, H; Pasare, C. Suppression of Inflammasome Activation by IRF8 and IRF4 in cDCs Is Critical for T Cell Priming. Cell Reports. 2020; 31:107604-107604.

Muench, DE; Olsson, A; Ferchen, K; Pham, G; Serafin, RA; Chutipongtanate, S; Dwivedi, P; Song, B; Hay, S; Chetal, K; et al. Mouse models of neutropenia reveal progenitor-stage-specific defects. Nature. 2020; 582:109-114.

Ng, S; Norwitz, GA; Pavlicev, M; Tilburgs, T; Simon, C; Norwitz, ER. Endometrial decidualization: The primary driver of pregnancy health. International Journal of Molecular Sciences. 2020; 21:4092-4092.

Oherle, K; Acker, E; Bonfield, M; Wang, T; Gray, J; Lang, I; Bridges, J; Lewkowich, I; Xu, Y; Ahlfeld, S; et al. Insulin-like Growth Factor 1 Supports a Pulmonary Niche that Promotes Type 3 Innate Lymphoid Cell Development in Newborn Lungs. Immunity. 2020; 52:275-294.e9.

Presicce, P; Cappelletti, M; Senthamaraikannan, P; Ma, F; Morselli, M; Jackson, CM; Mukherjee, S; Miller, LA; Pellegrini, M; Jobe, AH; et al. TNF-Signaling Modulates Neutrophil-Mediated Immunity at the Feto-Maternal Interface During LPS-Induced Intrauterine Inflammation. Frontiers in Immunology. 2020; 11.

Raynor, J; Lin, A; Hummel, SA; Lampe, K; Jordan, M; Hoebe, K; Hildeman, DA. The Variable Genomic NK Cell Receptor Locus Is a Key Determinant of CD4+ T Cell Responses During Viral Infection. Frontiers in Immunology. 2020; 11.

Toothaker, JM; Presicce, P; Cappelletti, M; Stras, SF; McCourt, CC; Chougnet, CA; Kallapur, SG; Konnikova, L. Immune Cells in the Placental Villi Contribute to Intra-amniotic Inflammation. Frontiers in Immunology. 2020; 11.

Tremblay, S; Driscoll, JJ; Rike-Shields, A; Hildeman, DA; Alloway, RR; Girnita, AL; Brailey, PA; Woodle, ES. A prospective, iterative, adaptive trial of carfilzomib-based desensitization. American Journal of Transplantation. 2020; 20:411-421.

Vieira, RD M; Meagher, A; Crespo, AC; Kshirsagar, SK; Iyer, V; Norwitz, ER; Strominger, JL; Tilburgs, T. Human term pregnancy decidual NK cells generate distinct cytotoxic responses. Journal of immunology (Baltimore, Md. : 1950). 2020; 204:3149-3159.

Woodle, ES; Tremblay, S; Rossi, A; Rojas, CC; Alloway, R; Roskin, K; Allman, D; Hildeman, D. Plasma cell targeting to prevent antibody-mediated rejection. American Journal of Transplantation. 2020; 20 Suppl 4:33-41.

Yarawsky, AE; Johns, SL; Schuck, P; Herr, AB. The biofilm adhesion protein Aap from Staphylococcus epidermidis forms zinc-dependent amyloid fibers. The Journal of biological chemistry. 2020; 295:4411-4427.

Yue, L; Sharma, V; Horvat, NP; Akuffo, AA; Beatty, MS; Murdun, C; Colin, C; Billington, JM R; Goodheart, WE; Sahakian, E; et al. HDAC11 deficiency disrupts oncogene-induced hematopoiesis in myeloproliferative neoplasms. Blood. 2020; 135:191-207.