Immunobiology

Publications

Adkins, PE; Yarawsky, AE; Herr, AB. The secreted staphylococcal biofilm protein Sbp forms biomolecular condensates in the presence of DNA. Protein Science. 2026; 35(2):e70485.

Al Souz, J; Wei, Y; Cui, C; Qu, R; Choi, J-Y; Wang, F; Moioffer, SJ; Barrett, J; Chernova, I; Nadella, M; Chen, P-M; Arazi, A; Ho, Y-C; Craft, J. Organ injury in systemic autoimmunity is mediated by stem-like CD8+ T cells arising from tissue-draining lymph nodes. Immunity. 2026; 59(6):1667-1687.e15.

Allgire, E; Mcalees, JW; Ahlbrand, RA; Mancz, E; Vollmer, LL; Winter, A; Mcmurray, KMJ; Maile, L; Sanders, B; Ryan, WG; Davidson, S; Mccullumsmith, RE; Lewkowich, IP; Sah, R. A novel interoceptive subfornical organ to infralimbic cortex mechanism relays airway inflammation effects on fear extinction. Journal of Neuroinflammation. 2026; 23(1).

Bandaru, R; Fu, H; Zheng, H; Liang, J; Wang, L; Gulati, S; Hinrichs, BH; Teng, M; Zhang, B; Kocherginsky, M; Gillison, ML; El-Gamal, D; Wise Draper, T; Liu, Y. Genome-wide variation in cell-free DNA end-motif entropy predicts immunotherapy response in head and neck cancer. Journal of Clinical Investigation. 2026; 136(13).

Bartram, J; Treichel, S; Song, BA; Xu, J; Sharma, D; Nasr, W; Frangiosa, M; Harley, A; Nemkov, T; D'alessandro, A; Salomonis, N; Grimes, HL; Filippi, M-D. Activation of a branched-chain amino acid rheostat restores replication-dependent hematopoietic stem cell fitness. Cell Stem Cell. 2026; 33(2):289-305.e6.

Burg, A; Ferguson, A; Elfers, E; Caine, R; Shi, T; Khorki, E; Maltzman, J; Baker, B; Hildeman, D. Tracking Viral-Specific CD4+ T Cells That Cross-React to Alloantigen. American Journal of Transplantation. 2026; 26(7):s727.

Burg, A; Ferguson, A; Rossi, A; Shields, A; Allman, D; Hildeman, D; Woodle, E. Human Long-Lived Plasma Cells Acquire Resistance to Proteasome Inhibitor-Based Desensitization Treatment by Upregulating Autophagy. American Journal of Transplantation. 2026; 26(7):s247.

Burg, A; Ferguson, A; Elfers, E; Caine, R; Shi, T; Khorki, E; Maltzman, J; Baker, B; Hildeman, D. Cross-Reactive Antiviral Memory CD8+ T Cells Display Resistance to Immunosuppression and Promote Accelerated Intragraft Inflammation. American Journal of Transplantation. 2026; 26(7):s725.

Caine, R; Caldwell, J; Wang, Y; Shi, T; Burg, A; Roskin, KM; Woodle, E; Hildeman, D. From Rejection to Histologic Resolution, Single Cell and Spatial Mapping of Persisting CD8+ T Cells within Kidney Allografts. American Journal of Transplantation. 2026; 26(7):s280.

Caldwell, JT; Wang, Y; Koby, A; Caine, R; Burg, A; Roskin, KM; Woodle, E; Hildeman, D. Multimodal Transcriptomic Evaluation of Renal Tubular Epithelium Reveals Injury Patterns in Acute Rejection. American Journal of Transplantation. 2026; 26(7):s558-s559.

Caldwell, J; Wang, Y; Shi, T; Burg, A; Koby, A; Steve, KE; Roskin, W; Hildeman, DA. 37 Injured proximal tubule cells are increased in kidney transplant rejection and are spatially located in distinct niches containing mixed immune cells. Journal of Clinical and Translational Science. 2026; 10(s1):11-11.

Cannata, AM; Mcalees, JW; Hargis, JM; Shankar, A; Huang, S; Divanovic, S; Lewkowich, IP. MAIT Cells Suppress IgE-Mediated Asthma via IFNγ-Dependent B Cell Regulation. Allergy. European Journal of Allergy and Clinical Immunology. 2026.

Chandra, S; Greis, KD; Chutipongtanate, S; Luebbering, N; Webster, A; Poisson, KE; Fisher, KS; Smiley, K; Marsh, RA; Jordan, MB; Davies, SM. Novel CSF biomarkers for facilitating diagnosis of CNS-HLH from other neuroinflammatory disorders. Blood advances. 2026; 10(4):960-972.

Chandra, S; Greis, KD; Chutipongtanate, S; Luebbering, N; Webster, A; Poisson, KE; Fisher, KS; Smiley, K; Marsh, RA; Jordan, MB; Davies, SM. Novel CSF biomarkers for facilitating diagnosis of CNS-HLH from other neuroinflammatory disorders. Blood advances. 2026; 10(4):960-972.

Chaton, CT; Murner, NR; Zamakhaeva, S; Rush, JS; Kenner, CW; Yarawsky, AE; Huang, L; Azadi, P; Herr, AB; Korotkova, N; Korotkov, KV. Enterococcus faecalis autolysin EpaU binds the enterococcal polysaccharide antigen via its teichoic acid-like repeats and modulates c-di-AMP signaling. mBio. 2026; 17(7):e0098826.

Chukwuma, P; Lazar, J; Brambley, C; Shi, T; Schurr, R; Gray, G; Foote, S; Burg, A; Cui, Y; Chan, A; White, F; Woodle, E; Birnbaum, M; Hildeman, D; Baker, B. The Allo-Antigen Specificity of a T Cell Driving Acute Cellular Rejection of a Kidney Allograft. American Journal of Transplantation. 2026; 26(7):s723.

Chung, H; Eom, J; Damen, MS; Stankiewicz, TE; Sawada, K; Alarcon, PC; Ulanowicz, CJ; Wayland, JL; Deepe, GS; Divanovic, S. Zinc suppresses Stat3-driven IL-6 production in primary mouse adipocytes. Frontiers in Immunology. 2026; 17:1714168.

Colom Díaz, PA; Mistry, JJ; Young, KA; Chou, C-H; Boyer, N; Levine, RL; Salomonis, N; Grimes, HL; Trowbridge, JJ. Metallothionein 1 mediates growth and survival of Dnmt3a;Npm1-mutant acute myeloid leukemia. Haematologica. 2026; 111(1):373-378.

Drucker, M; Lee, D; Bowman, M; Zhang, X; Kain, BN; Nicolet, D; Bandopadhyay, R; Singh, V; Wang, Z; Stone, RM; Grimes, HL; Eisfeld, A-K; Bowman, RL; Miles, LA. Genotype-immunophenotype relationships in NPM1-mutated AML clonal evolution uncovered by single-cell multiomic analysis. Blood. 2026; 147(26):3209-3216.

Eshleman, EM; Rice, T; Waddell, A; Kumar, S; Didriksen, BJ; Engleman, L; Vidyant, S; Sayed, M; Karns, R; Lim, H-W; Denson, LA; Alenghat, T. Tuft cells protect against intestinal inflammation through histone deacetylase 3. Mucosal Immunology. 2026; 100356.

Eswar, S; Koenig, ZT; Tursi, AR; Cobeña-Reyes, J; Tilburgs, T; Andorf, S. CytoBatchFlagR: A Comprehensive Framework to Objectively Assess High-Parameter Cytometry Data for Batch Effects. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2026; 109(4):241-256.

Fava, A; Wagner, CA; Guthridge, CJ; Macwana, S; Dejager, W; Munroe, ME; Izmirly, P; Belmont, HM; Diamond, B; Davidson, A; Petri, M; Guthridge, JM; Buyon, J; James, JA. Serum Soluble Mediator Signatures of Lupus Nephritis: Histologic Features and Response to Treatment. Arthritis Care and Research. 2026; 78(4):520-527.

Gill, KK; Moore, C; Nwogu, O; Kroner, JW; Chang, W-C; Burkle, J; Virolainen, SJ; Stevens, ML; Baatyrbek, A; Miraldi, ER; Martin, LJ; Andorf, S; Khurana Hershey, GK; Roskin, KM. B-Cell Repertoire of Children With Atopic Dermatitis Exhibits Altered IgE Maturation Associated With Allergic Food Sensitization. Allergy. European Journal of Allergy and Clinical Immunology. 2026; 81(2):513-523.

Hamp, E; Oelschläger, L; Kain, BN; Nicolet, D; Mrozek, K; Miller, KE; Bollas, A; Walker, MC; Walker, CJ; Buss, J; Salomonis, N; Grimes, HL; Mardis, ER; Eisfeld, A-K. Abstract 7897: Novel Rho-GTPase regulatory protein gene family variants are frequent and associate with poor survival in patients (pts) with acute myeloid leukemia (AML) Cancer Research. 2026; 86(7_Supplement):7897-7897.

Hayashi, K; Lancey, J; Giarraputo, A; Rosales, I; Hildeman, D; Woodle, ES; Luo, X; Tunbridge, M; Yu, Y; Kwun, J; Colvin, RB; Madsen, JC; Cosimi, AB; Alessandrini, A. Development and Validation of a Diagnostic Gene Panel That Distinguishes Graft Tolerance from Rejection. American Journal of Transplantation. 2026; 26(7):s340.

Heekin, S; Lopez-Nunez, O; Smith, J; Denson, N; Denson, L; Miethke, A; Collins, MH; Dillman, J; Miraldi, E; Kofron, JM; Dhaliwal, J; Erdman, L. Implications of Model Loss and Configuration for Sparse Histological Segmentation. In: Machine Learning Methods in Biomedical Field. Springer Nature; 2026:189-217.

Hoover, PJ; Eisenhaure, TM; Hodgin, J; Apruzzese, W; Mears, J; Peters, M; Jones, T; Shah, SI; Kamal, H; Leavitt, R; Diamond, B; Davidson, A; Hacohen, N; Arazi, A. Deep profiling of lupus nephritis kidneys reveals dynamic changes in myeloid cells associated with disease progression. Annals of the Rheumatic Diseases. 2026; 85(7):1324-1340.

Katko, A; Korinfskaya, S; Bejjani, AT; Owoeye, SM; Yang, ZF; Rudrapatna, AN; Potter, S; Wayman, JA; Kotliar, M; Kottyan, LC; Barski, A; Miraldi, ER. Gene regulatory network determinants of rapid recall in human memory CD4+ T cells. Cell reports. 2026; 45(4):117103.

Koby, A; Burg, A; Caine, R; Woodle, E; Hildeman, D; Caldwell, J. Predicting Kidney Allograft Survival Using Cell Proportions from Single-Cell RNA Sequencing Guided Deconvolution. American Journal of Transplantation. 2026; 26(7):s918.

Koenig, ZT; Eswar, S; Tsuda, S; Schuldt, N; Chougnet, CA; Forde, B; Andorf, S; Tilburgs, T. Decidual CD4 Effector Memory and Resident Memory T Cells Respond to Cord Blood Allo-Antigens. American Journal of Reproductive Immunology. 2026; 95(2):e70213.

Lin, Y-S; Alonso, V; Singh, A; Liu, Y; Tang, Y; Mehta, A; King, JK; Paing, M; Salomonis, N; Grimes, HL; Chia, JJ; Rao, DS; Hoffmann, A. Dysregulated NF-κB dynamics impair proteostasis and drive premature differentiation in aging B cell development. Mining Technology Transactions of the Institutions of Mining and Metallurgy. 2026; 1(3):100051.

Merola, J; Joshi, R; Burg, A; Caldwell, J; Hildeman, D. Development of a Fully Human Model of Kidney Allorejection Using Normothermic Machine Perfusion. American Journal of Transplantation. 2026; 26(7):s572.

Miller-Handley, H; Maguire, M; Woodle, E; Hildeman, D; Way, S. Distinct Triggers for Acute Cellular Rejection Evoke Divergent Allospecific CD4+ and CD8+ T Cell Responses. American Journal of Transplantation. 2026; 26(7):s556-s557.

Moreno-Fernandez, ME; Divanovic, S. B cells just got a workout. Cell. 2026; 189(11):3181-3183.

Nalapareddy, K; Haslam, DB; Kissmann, A-K; Alenghat, T; Stahl, S; Rosenau, F; Zheng, Y; Geiger, H. Microbiota from young mice restore the function of aged ISCs. Stem Cell Reports. 2026; 21(2):102788.

Peters, AL; Depasquale, E; Steinkamp, S; Woodle, E; Hildeman, D. Single Cell RNA Sequencing Reveals Alterations in Activated, Clonally Expanded CD8+ T Cell and Kupffer Cell Populations in Early and Late T Cell Mediated Liver Transplant Rejection. American Journal of Transplantation. 2026; 26(7):s368.

Peters, AL; Steinkamp, S; Depasquale, E; Huppert, S; Burwinkel, J; Woodle, E; Hildeman, D. Multiome Sequencing of Chronic Ductopenic Rejection Reveals Roles for Th2 Immunity and Activated Fibroblasts in Cholangiocyte Injury. American Journal of Transplantation. 2026; 26(7):s561-s562.

Presicce, P; Beckman, D; Diniz, GB; Cappelletti, M; Ott, S; Bercovici, S; Kale, S; Babb, P; Mohole, J; Richardson, LS; Chougnet, CA; Way, SS; Morrison, JH; Kallapur, SG. Diffuse neuroinflammation and immature neuron loss in fetal Rhesus macaques after short-term intrauterine infection. Journal of Neuroinflammation. 2026; 23(1):60.

Sakaue, S; Raychaudhuri, S. Early and late RNA eQTL are driven by different genetic mechanisms. Nature Communications. 2026; 17(1).

Sawada, K; Eom, J; Mahoney-Sutherland, BA; Stankiewicz, TE; Oates, JR; Giles, DA; Alarcon, PC; Damen, MSMA; Cannata, A; Hargis, J; Hogan, SP; Salomonis, N; Moreno-Fernandez, ME; Divanovic, S. Ambient temperature regulates CD4+ T cell tonic T cell receptor signaling and responsiveness. iScience. 2026; 29(5):115801.

Schurr, RM; Burg, A; Shi, T; Chukwuma, P; Brambley, CA; Maltzman, J; Hildeman, D; Baker, BM. Leveraging Heterologous Immunity to Identify the Allospecific Targets of TCRs Driving Acute Cellular Rejection. American Journal of Transplantation. 2026; 26(7):s725-s726.

Tilburgs, T. Decidual immune activation by extravillous trophoblasts drives maternal-fetal tolerance and immunity. Trends in Immunology. 2026; 47(3):180-183.

Tsuda, S; Dasenbrock, A; Mahajan, S; Tilburgs, T. Purification of HLA-G+ Extravillous Trophoblasts from Human Term Placental Tissues for Phenotyping and Functional Analysis. Journal of Visualized Experiments. 2026; 229.

Ulanowicz, CJ; Alarcon, PC; Damen, MSMA; Wayland, JL; Sawada, K; Eom, J; Stankiewicz, TE; Chung, H; Lampe, K; Szabo, S; Moreno-Fernandez, ME; Salomonis, N; Divanovic, S. Distinct inflammatory programming of thoracic cavity white adipose immune cells regulates influenza pathogenesis. Journal of Infectious Diseases. 2026.

Verkamp, B; Jordan, MB; Allen, CE. Pediatric hemophagocytic lymphohistiocytosis: current conceptualization, diagnosis, and treatment. Blood. 2026; 147(10):1019-1036.

Wang, Y; Adeleke, D; Xie, X; Yang, ZF; Wang, X; Loi, G; Yang Vom Hofe, A; Singh, M; Malik, A; Kudira, R; Dillman, JR; Trout, AT; Miraldi, ER; Miethke, AG. Macrophage signaling associates with fibrogenic program activation in periductal fibroblasts in pediatric primary sclerosing cholangitis. JCI Insight. 2026; 11(13).

Zeng, AGX; Nagree, MS; Jakobsen, NA; Shah, S; Varesi, A; Kang, JRW; Murison, A; Cheong, J-G; Turkalj, S; Zhang, X; Awadalla, P; Vyas, P; Dick, JE; Xie, SZ. Human haematopoietic stem cells remember inflammatory stress. Nature. 2026; 655(8122):458-467.

Zoref-Lorenz, A; Allen, CE; Behrens, EM; Chandrakasan, S; Chien, M; Hermiston, ML; Hinson, AP; Intzes, S; Isakoff, MS; Leiding, JW; Modica, R; Riskalla, M; Baker, A; Ward, B. Emapalumab use in malignancy-associated hemophagocytic lymphohistiocytosis in the United States: the REAL-HLH study. Blood advances. 2026; 10(5):1564-1575.