Molecular Cardiovascular Biology

Faculty Labs

Our lab studies how nuclear envelope function and chromosome organization influence cardiovascular disease, aging, and lamin-related disorders to better understand disease mechanisms and identify therapeutic targets.

Our lab studies the molecular mechanisms of cardiac injury and remodeling to develop gene therapy strategies that promote heart repair and improve heart function after injury.

Our lab studies the molecular mechanisms of cardiovascular and skeletal muscle disease, with a focus on microproteins, to uncover new biology and develop targeted therapies.

Our lab studies skeletal muscle development, regeneration, and cell fusion to better understand muscle function, aging, and disease and to develop new therapeutic approaches.

Our lab studies the molecular and cellular mechanisms of heart and skeletal muscle disease to identify new therapeutic targets related to cell death, signaling, remodeling, and muscle function.

Our lab investigates gene-regulatory networks, with a focus on the transcription factor PITX2, to understand how developmental programs are controlled and to identify therapeutic targets for diseases such as cardiac arrhythmias.

Our lab studies how cardiac progenitor cell selection and signaling pathways regulate heart development to better understand congenital heart defects and improve strategies for cardiac regeneration and repair.

Our lab studies the molecular regulatory mechanisms that control heart development and disease, with the goal of identifying how developmental signaling pathways are reactivated in cardiovascular disease and can be targeted for therapy.