Publications
Publications
Localized Prox1 Regulates Aortic Valve Endothelial Cell Diversity and Extracellular Matrix Stratification in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 2023; 43(8):1478-1493.
Btg1 and Btg2 regulate neonatal cardiomyocyte cell cycle arrest. Journal of Molecular and Cellular Cardiology. 2023; 179:30-41.
Cardiomyocyte-fibroblast crosstalk in the postnatal heart. Frontiers in Cell and Developmental Biology. 2023; 11:1163331.
Therapeutic CCR2 Blockade Prevents Inflammation and Alleviates Myxomatous Valve Disease in Marfan Syndrome. JACC: Basic to Translational Science. 2022; 7(11):1143-1157.
Porcine Models of Heart Regeneration. Journal of Cardiovascular Development and Disease. 2022; 9(4).
Epigenetic Regulation of Heart Failure: Cell Type Matters. Circulation Research. 2021; 129(3):414-416.
Periostin-expressing Schwann cells and endoneurial cardiac fibroblasts contribute to sympathetic nerve fasciculation after birth. Journal of Molecular and Cellular Cardiology. 2021; 154:124-136.
Transcriptional Regulation of Postnatal Cardiomyocyte Maturation and Regeneration. International Journal of Molecular Sciences. 2021; 22(6).
Cardiomyocyte cell cycling, maturation, and growth by multinucleation in postnatal swine. Journal of Molecular and Cellular Cardiology. 2020; 146:95-108.
Mechanisms of heart valve development and disease. Development. 2020; 147(13).
To EndoMT or Not to EndoMT: Zebrafish Heart Valve Development. Circulation Research. 2020; 126(8):985-987.
Ube2v1 Positively Regulates Protein Aggregation by Modulating Ubiquitin Proteasome System Performance Partially Through K63 Ubiquitination. Circulation Research. 2020; 126(7):907-922.
Deficiency of Circulating Monocytes Ameliorates the Progression of Myxomatous Valve Degeneration in Marfan Syndrome. Circulation. 2020; 141(2):132-146.
Developmental Pathways and Aortic Valve Calcification. In: Cardiovascular Calcification and Bone Mineralization. Springer Nature; 2020:47-71.
Scar Formation with Decreased Cardiac Function Following Ischemia/Reperfusion Injury in 1 Month Old Swine. Journal of Cardiovascular Development and Disease. 2019; 7(1).
Calcification and extracellular matrix dysregulation in human postmortem and surgical aortic valves. Heart. 2019; 105(21):1616-1621.
Postnatal Cardiac Development and Regenerative Potential in Large Mammals. Pediatric Cardiology. 2019; 40(7):1345-1358.
Cardiac Fibroblasts and the Extracellular Matrix in Regenerative and Nonregenerative Hearts. Journal of Cardiovascular Development and Disease. 2019; 6(3).
Maturation of heart valve cell populations during postnatal remodeling. Development. 2019; 146(12).
Endothelial Cell Lineage Analysis Does Not Provide Evidence for EMT in Adult Valve Homeostasis and Disease. Anatomical Record. 2019; 302(1):125-135.
Macrophage Transitions in Heart Valve Development and Myxomatous Valve Disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 2018; 38(3):636-644.
Loss of β-catenin in resident cardiac fibroblasts attenuates fibrosis induced by pressure overload in mice. Nature Communications. 2017; 8(1):712.
Loss of Axin2 results in impaired heart valve maturation and subsequent myxomatous valve disease. Cardiovascular Research (CVR). 2017; 113(1):40-51.
Bone Morphogenetic Protein Signaling Is Required for Aortic Valve Calcification. Arteriosclerosis, Thrombosis, and Vascular Biology. 2016; 36(7):1398-1405.
Overexpression of Tbx20 in Adult Cardiomyocytes Promotes Proliferation and Improves Cardiac Function After Myocardial Infarction. Circulation. 2016; 133(11):1081-1092.
Loss of β-catenin promotes chondrogenic differentiation of aortic valve interstitial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 2014; 34(12):2601-2608.
Differential expression of embryonic epicardial progenitor markers and localization of cardiac fibrosis in adult ischemic injury and hypertensive heart disease. Journal of Molecular and Cellular Cardiology. 2013; 65:108-119.
Enhanced BMP signaling in cranial neural crest cells induces aberrant chondrogenesis by upregulating Tbx20 expression during craniofacial development. Biochemical and Biophysical Research Communications. 2025; 765:151834.
Transforming growth factor β-dependent regulation of cardiomyocyte maturation. Journal of Molecular and Cellular Cardiology Plus. 2025; 12:100400.
Baby breaths: Honoring Kurt Albertine and his contributions to respiratory research in young mammals and to The Anatomical Record. Anatomical Record. 2025; 308(4):1018-1025.
GDF10 promotes rodent cardiomyocyte maturation during the postnatal period. Journal of Molecular and Cellular Cardiology. 2025; 201:16-31.
Klotho mutation does not accelerate intervertebral disc aging in mice. The FASEB Journal. 2025; 39(1):e70279.
Unraveling the Mechanisms of Valvular Heart Disease to Identify Medical Therapy Targets: A Scientific Statement From the American Heart Association. Circulation. 2024; 150(6):e109-e128.
APOE-NOTCH axis governs elastogenesis during human cardiac valve remodeling. Nature Cardiovascular Research. 2024; 3(8):933-950.
Wnt Signaling Inhibition Prevents Postnatal Inflammation and Disease Progression in Mouse Congenital Myxomatous Valve Disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 2024; 44(7):1540-1554.
Dynamic changes in mitral valve extracellular matrix, tissue mechanics and function in a mouse model of Marfan syndrome. Matrix Biology. 2024; 126:1-13.
Macrophage lineages in heart development and regeneration. 2024:1-17.
Quality Over Quantity: BMP-9 Regulation of Scar Formation After Myocardial Infarction. JACC: Basic to Translational Science. 2023; 8(10):1331-1333.
PROX1 Inhibits PDGF-B Expression to Prevent Myxomatous Degeneration of Heart Valves. Circulation Research. 2023; 133(6):463-480.
Col1a2-Deleted Mice Have Defective Type I Collagen and Secondary Reactive Cardiac Fibrosis with Altered Hypertrophic Dynamics. Cells. 2023; 12(17).
Abstract P2106: Transforming Growth Factor β-dependent Regulation Of Cardiomyocyte Maturation. Circulation Research. 2023; 133(Suppl_1).
Abstract P1178: APOE-NOTCH Axis Governs Elastogenesis During Human Cardiac Valve Remodeling. Circulation Research. 2023; 133(Suppl_1).
Abstract P1012: Wnt Signaling Is Required For Myxomatous Valve Disease In A Mouse Model Of Marfan Syndrome. Circulation Research. 2023; 133(Suppl_1).
Localized Prox1 Regulates Aortic Valve Endothelial Cell Diversity and Extracellular Matrix Stratification in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 2023; 43(8):1478-1493.
Btg1 and Btg2 regulate neonatal cardiomyocyte cell cycle arrest. Journal of Molecular and Cellular Cardiology. 2023; 179:30-41.
Cardiomyocyte-fibroblast crosstalk in the postnatal heart. Frontiers in Cell and Developmental Biology. 2023; 11:1163331.
Abstract 9555: Human Valve Atlas in Health and Disease. Circulation. 2022; 146(Suppl_1):a9555-a9555.
Therapeutic CCR2 Blockade Prevents Inflammation and Alleviates Myxomatous Valve Disease in Marfan Syndrome. JACC: Basic to Translational Science. 2022; 7(11):1143-1157.
Abstract P1112: Inhibition Of Wnt Signaling Protects Against Myxomatous Valve Disease In A Mouse Model Of Marfan Syndrome. Circulation Research. 2022; 131(Suppl_1):ap1112-ap1112.
A clinical scoring system for early onset (neonatal) Marfan syndrome. Genetics in Medicine. 2022; 24(7):1503-1511.
Measuring cardiomyocyte cell-cycle activity and proliferation in the age of heart regeneration. American Journal of Physiology. Heart and Circulatory Physiology. 2022; 322(4):H579-H596.
Porcine Models of Heart Regeneration. Journal of Cardiovascular Development and Disease. 2022; 9(4).
OP023: A clinical scoring system for early onset (neonatal) Marfan syndrome. Genetics in Medicine. 2022; 24(3):s353.
Epigenetic Regulation of Heart Failure: Cell Type Matters. Circulation Research. 2021; 129(3):414-416.
Periostin-expressing Schwann cells and endoneurial cardiac fibroblasts contribute to sympathetic nerve fasciculation after birth. Journal of Molecular and Cellular Cardiology. 2021; 154:124-136.
Transcriptional Regulation of Postnatal Cardiomyocyte Maturation and Regeneration. International Journal of Molecular Sciences. 2021; 22(6).
Timing of Repair in Tetralogy of Fallot: Effects on Outcomes and Myocardial Health. Cardiology in Review. 2021; 29(2):62-67.
Macrophage lineages in heart valve development and disease. Cardiovascular Research (CVR). 2021; 117(3):663-673.
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