Molecular Cardiovascular Biology

Publications

Auchampach, J; Han, L; Huang, GN; Kühn, B; Lough, JW; O'Meara, CC; Payumo, AY; Rosenthal, NA; Sucov, HM; Yutzey, KE; et al. Measuring cardiomyocyte cell-cycle activity and proliferation in the age of heart regeneration. American Journal of Physiology: Heart and Circulatory Physiology. 2022; 322:H579-H596.

Bowers, SL K; Meng, Q; Molkentin, JD. Fibroblasts orchestrate cellular crosstalk in the heart through the ECM. 2022; 1:312-321.

Boyer, JG; Huo, J; Han, S; Havens, JR; Prasad, V; Lin, BL; Kass, DA; Song, T; Sadayappan, S; Khairallah, RJ; et al. Depletion of skeletal muscle satellite cells attenuates pathology in muscular dystrophy. Nature Communications. 2022; 13:2940.

Brito-Estrada, O; Hassel, KR; Makarewich, CA. An Integrated Approach for Microprotein Identification and Sequence Analysis. Jove-Journal of Visualized Experiments. 2022; 2022.

Gamage, DG; Melikov, K; Munoz-Tello, P; Wherley, TJ; Focke, LC; Leikina, E; Huffman, E; Diao, J; Kojetin, DJ; Prasad, V; et al. Phosphatidylserine orchestrates Myomerger membrane insertions to drive myoblast fusion. Proceedings of the National Academy of Sciences of USA. 2022; 119:e2202490119.

Hindi, SM; Millay, DP. All for One and One for All: Regenerating Skeletal Muscle. Cold Spring Harbor perspectives in biology. 2022; 14:a040824.

Howard, AG A; Nguyen, AC; Tworig, J; Ravisankar, P; Singleton, EW; Li, C; Kotzur, G; Waxman, JS; Uribe, RA. Elevated Hoxb5b Expands Vagal Neural Crest Pool and Blocks Enteric Neuronal Development in Zebrafish. Frontiers in Cell and Developmental Biology. 2022; 9:803370.

Jebessa, ZH; Schnieder, A; Dewenter, M; Berlin, M; Makarewich, C; Olson, EN; Freichel, M; Backs, J; Busch, M; Most, P. S100A1 & STRIT1 redundantly governs responsiveness of the heart to hemodynamic stress via modulation of SERCA2A activity. Journal of Molecular and Cellular Cardiology. 2022; 173:164.

Jiang, Z; Elsarrag, SZ; Duan, Q; LaGory, EL; Wang, Z; Alexanian, M; McMahon, S; Rulifson, IC; Winchester, S; Wang, Y; et al. KLF15 cistromes reveal a hepatocyte pathway governing plasma corticosteroid transport and systemic inflammation. Science Advances. 2022; 8:eabj2917.

Kimura, M; Iguchi, T; Iwasawa, K; Dunn, A; Thompson, WL; Yoneyama, Y; Chaturvedi, P; Zorn, AM; Wintzinger, M; Quattrocelli, M; et al. En masse organoid phenotyping informs metabolic-associated genetic susceptibility to NASH. Cell. 2022; 185:4216-4232.e16.

Li, Y; Li, C; Liu, Q; Wang, L; Bao, AX; Jung, JP; Dodlapati, S; Sun, J; Gao, P; Zhang, X; et al. Loss of Acta2 in cardiac fibroblasts does not prevent the myofibroblast differentiation or affect the cardiac repair after myocardial infarction. Journal of Molecular and Cellular Cardiology. 2022; 171:117-132.

Liu, S; Li, RG; Martin, JF. The cell-autonomous and non-cell-autonomous roles of the Hippo pathway in heart regeneration. Journal of Molecular and Cellular Cardiology. 2022; 168:98-106.

Liu, S; Martin, JF. RNA splicing to cytoskeleton: A new path to cardiomyocyte ploidy and division?. Developmental Cell. 2022; 57:945-946.

Liu, Z; Liu, Y; Yu, Z; O'Donnell, A; Guo, M; Chen, Y; Glass, I; Yutzey, K; Wu, J; Miao, Y; et al. Abstract 9555: Human Valve Atlas in Health and Disease. Circulation. 2022; 146:a9555.

Makarewich, CA; Munir, AZ; Bezprozvannaya, S; Gibson, AM; Kim, SY; Martin-Sandoval, MS; Mathews, TP; Szweda, LI; Bassel-Duby, R; Olson, EN. The cardiac-enriched microprotein mitolamban regulates mitochondrial respiratory complex assembly and function in mice. Proceedings of the National Academy of Sciences of USA. 2022; 119:e2120476119.

Makarewich, CA; Thum, T. Exercise-Induced Long Noncoding RNAs As New Players in Cardiac Hypertrophy. Circulation. 2022; 145:1234-1237.

Millay, DP. Regulation of the myoblast fusion reaction for muscle development, regeneration, and adaptations. Experimental Cell Research. 2022; 415:113134.

Molkentin, JD; Leinwand, LA. Remembering Jeff Robbins: The Father of Cardiac Transgenesis. JACC: Basic to Translational Science. 2022; 7:1063-1065.

Nerger, BA; Jones, TM; Rose, KW J; Barqué, A; Weinbaum, JS; Petrie, RJ; Chang, J; Vanhoutte, D; LaDuca, K; Hubmacher, D; et al. The matrix in focus: new directions in extracellular matrix research from the 2021 ASMB hybrid meeting. Biology Open. 2022; 11:bio059156.

Paulissen, E; Palmisano, NJ; Waxman, JS; Martin, BL. Somite morphogenesis is required for axial blood vessel formation during zebrafish embryogenesis. eLife. 2022; 11:e74821.

Perl, E; Ravisankar, P; Beerens, ME; Mulahasanovic, L; Smallwood, K; Sasso, MB; Wenzel, C; Ryan, TD; Komár, M; Bove, KE; et al. Stx4 is required to regulate cardiomyocyte Ca2+ handling during vertebrate cardiac development. HGG Advances. 2022; 3:100115.

Prabakaran, AD; Panta, M; Quattrocelli, M. Commentary for “antagonizing urotensin receptor is a novel therapeutic strategy for glucocorticoid‐induced skeletal muscle atrophy”. Clinical and Translational Discovery. 2022; 2.

Prasad, V; Molkentin, JD. At the Brink of Human Therapy to Generate New Myocytes in the Adult Injured Heart. Circulation. 2022; 145:1356-1358.

Quattrocelli, M; Wintzinger, M; Miz, K; Levine, DC; Peek, CB; Bass, J; McNally, EM. Muscle mitochondrial remodeling by intermittent glucocorticoid drugs requires an intact circadian clock and muscle PGC1α. Science Advances. 2022; 8:eabm1189.

Quattrocelli, M; Wintzinger, M; Miz, K; Panta, M; Durumutla, HB; Prabakaran, AD. Abstract P3035: Time-of-intake Regulates Glucocorticoid Effects On Heart Metabolism And Function Through Cardiomyocyte-autonomous Mechanisms. Circulation Research. 2022; 131:ap3035.

Quattrocelli, M; Wintzinger, M; Miz, K; Panta, M; Prabakaran, AD; Barish, GD; Chandel, NS; McNally, EM. Intermittent prednisone treatment in mice promotes exercise tolerance in obesity through adiponectin. The Journal of Experimental Medicine. 2022; 219:e20211906.

Rowton, M; Perez-Cervantes, C; Hur, S; Jacobs-Li, J; Lu, E; Deng, N; Guzzetta, A; Hoffmann, AD; Stocker, M; Steimle, JD; et al. Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages. Developmental Cell. 2022; 57:2181-2203.e9.

Salamone, IM; Quattrocelli, M; Barefield, DY; Page, PG; Tahtah, I; Hadhazy, M; Tomar, G; McNally, EM. Intermittent glucocorticoid treatment enhances skeletal muscle performance through sexually dimorphic mechanisms. The Journal of Clinical Investigation. 2022; 132:e149828.

Velayutham, N; Yutzey, KE. Porcine Models of Heart Regeneration. Journal of Cardiovascular Development and Disease. 2022; 9:93.

Wessendarp, M; Watanabe-Chailland, M; Liu, S; Stankiewicz, T; Ma, Y; Kasam, RK; Shima, K; Chalk, C; Carey, B; Rosendale, LR; et al. Role of GM-CSF in regulating metabolism and mitochondrial functions critical to macrophage proliferation. Mitochondrion. 2022; 62:85-101.

Wintzinger, M; Panta, M; Miz, K; Prabakaran, AD; Durumutla, HB; Sargent, M; Peek, CB; Bass, J; Molkentin, JD; Quattrocelli, M. Impact of circadian time of dosing on cardiomyocyte-autonomous effects of glucocorticoids. Molecular Metabolism. 2022; 62:101528.

Xu, N; Yutzey, KE. Abstract P1112: Inhibition Of Wnt Signaling Protects Against Myxomatous Valve Disease In A Mouse Model Of Marfan Syndrome. Circulation Research. 2022; 131:ap1112.

Xu, N; Yutzey, KE. Therapeutic CCR2 Blockade Prevents Inflammation and Alleviates Myxomatous Valve Disease in Marfan Syndrome. JACC: Basic to Translational Science. 2022; 7:1143-1157.

Yedigaryan, L; Martínez-Sarrà, E; Giacomazzi, G; Giarratana, N; van der Veer, BK; Rotini, A; Querceto, S; Grosemans, H; Cortés-Calabuig, Á; Salucci, S; et al. Extracellular vesicle-derived miRNAs improve stem cell-based therapeutic approaches in muscle wasting conditions. Frontiers in Immunology. 2022; 13:977617.

Zampese, E; Wokosin, DL; Gonzalez-Rodriguez, P; Guzman, JN; Tkatch, T; Kondapalli, J; Surmeier, WC; D’Alessandro, KB; De Stefani, D; Rizzuto, R; et al. Ca2+ channels couple spiking to mitochondrial metabolism in substantia nigra dopaminergic neurons. Science Advances. 2022; 8:eabp8701.

Zarate, Y; Morris, S; Blackshare, A; Algaze, C; Connor, B; Kim, A; Yutzey, K; Miller, E; Weaver, KN; Collins, T. OP023: A clinical scoring system for early onset (neonatal) Marfan syndrome. Genetics in Medicine. 2022; 24:s353.

Zarate, YA; Morris, SA; Blackshare, A; Algaze, CA; Connor, BS; Kim, AJ; Yutzey, KE; Miller, EM; Weaver, KN; Collins, RT. A clinical scoring system for early onset (neonatal) Marfan syndrome. Genetics in Medicine. 2022; 24:1503-1511.

Zhang, S; Liu, S; Leach, JP; Li, K; Perin, EC; Martin, JF. Gene Therapy Knockdown of Hippo Signaling Resolves Arrhythmic Events in Pigs After Myocardial Infarction. Circulation. 2022; 146:1558-1560.