Molecular Cardiovascular Biology

Publications

Abay, E; Huo, J; Molkentin, J. Mitochondrial Transplantation Therapeutics: Assessing Mitochondrial Viability in Extracellular Milieu. Journal of Molecular and Cellular Cardiology Plus. 2025; 12:100370.

Calvo, C; Smith, C; Song, T; Montecino-Morales, F; Sadayappan, S; Millay, DP; Kim, M. Loss of Ufsp1 does not cause major changes at the neuromuscular junction. Editor, Hitachi K. PloS one. 2025; 20:e0328690.

Chaikin, CA; Thakkar, AV; Steffeck, AW T; Pfrender, EM; Hung, K; Zhu, P; Waldeck, NJ; Nozawa, R; Song, W; Futtner, CR; Quattrocelli, M; Bass, J; Ben-Sahra, I; Peek, CB. Control of circadian muscle glucose metabolism through the BMAL1-HIF axis in obesity. Proceedings of the National Academy of Sciences of USA. 2025; 122:e2424046122.

Cleary, SR; Teng, AC T; Kongmeneck, AD; Fang, X; Phillips, TA; Cho, EE; Smith, RA; Karkut, P; Makarewich, CA; Kekenes-Huskey, PM; Gramolini, AO; Robia, SL. Dilated cardiomyopathy variant R14del increases phospholamban pentamer stability, blunting dynamic regulation of calcium. The Journal of biological chemistry. 2025; 301:108118.

Coughlin, TM; Makarewich, CA. Emerging roles for microproteins as critical regulators of endoplasmic reticulum function and cellular homeostasis. Seminars in Cell and Developmental Biology. 2025; 170:103608.

Duong, TB; Fernandes, AT; Ravisankar, P; Talbot, JC; Waxman, JS. Tbx1-dependent and independent pathways promote six gene expression downstream of retinoic acid signaling to determine cardiomyocyte number in zebrafish. Developmental Biology. 2025; 524:17-28.

Gibson, AM; Pan, X; Brito-Estrada, O; Teixeira, JA; Carl, LK; Yue, Y; Kamradt, ML; Burke, MJ; Wadding-Lee, CA; Yao, G; Herzog, RW; Duan, D; Makarewich, CA. DWORF expression is reduced in a large animal model of Duchenne muscular dystrophy. DMM Disease Models and Mechanisms. 2025; 18:dmm052285.

Hassel, K; Gibson, A; Seflova, J; Cho, E; Blair, NS; Anderson, D; Robia, S; Makarewich, C. Another-regulin regulates cardiomyocyte calcium handling via integration of neuroendocrine signaling with SERCA2a activity. Journal of Molecular and Cellular Cardiology Plus. 2025; 12:100386.

Hong, J; Shah, V; Krishnan, R; Gomez-Stallons, MV; Poudel, S; Yutzey, KE; Dahia, CL. Klotho mutation does not accelerate intervertebral disc aging in mice. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2025; 39:e70279.

Huo, J; Abay, E; Zou, H; Lin, S; Wilson, J; Molkentin, J. Examination of mitochondrial calcium dynamic fluxing in the heart on preferential fuel selection. Journal of Molecular and Cellular Cardiology Plus. 2025; 12:100392.

Johansen, AK Z; Kasam, RK; Vagnozzi, RJ; Lin, SC J; Gomez-Arroyo, JG; Gomez-Arroyo, J; Shittu, A; Bowers, SL K; Kuwabara, Y; Grimes, KM; Warrick, K; Sargent, MA; Baldwin, TA; Quaggin, SE; Barski, A; Molkentin, JD. Transcription Factor 21 Regulates Cardiac Myofibroblast Formation and Fibrosis. Circulation Research. 2025; 136:44-58.

Joss-Moore, LA; Yutzey, KE. Baby breaths: Honoring Kurt Albertine and his contributions to respiratory research in young mammals and to The Anatomical Record. The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology. 2025; 308:1018-1025.

Kasam, RK; Grimes, K; Johansen, AK; Kuwabara, Y; Blair, S; Lin, S; Vagnozzi, R; Molkentin, J. Selective activation of cardiac macrophage subtypes influences pathophysiology. Journal of Molecular and Cellular Cardiology Plus. 2025; 12:100369.

Kuwabara, Y; Blair, NS; Keezer, C; Kasam, RK; Warrick, K; Lin, S; Molkentin, JD. VWA7 Expression In The Mouse Heart Induces Maladaptation And Inflammatory Dependent Fibrosis. Journal of Molecular and Cellular Cardiology Plus. 2025; 12:100356.

Li, R; Li, X; Morikawa, Y; Grisanti, F; Meng, F; Tsai, C; Zhao, Y; Liu, L; Kim, J; Xie, B; Klysik, E; Liu, S; Samee, MA H; Martin, J. YAP Induces a Neonatal Like Pro-Renewal Niche in the Adult Heart. Journal of Molecular and Cellular Cardiology Plus. 2025; 12:100304.

Liu, S; Deshmukh, V; Meng, F; Wang, Y; Morikawa, Y; Steimle, JD; Li, RG; Wang, J; Martin, JF. Microtubules Sequester Acetylated YAP in the Cytoplasm and Inhibit Heart Regeneration. Circulation. 2025; 151:59-75.

Mia, S; Siokatas, G; Sidiropoulou, R; Hoffman, M; Fragkiadakis, K; Markopoulou, E; Elesawy, MI; Roy, R; Blair, S; Kuwabara, Y; Schilling, JD; Molkentin, JD; Marketou, M; Drosatos, K. Hepato-cardiac interorgan communication controls cardiac hypertrophy via combined endocrine-autocrine FGF21 signaling. Cell Reports Medicine. 2025; 6:102125.

Minerath, R; Kasam, R; Grimes, K; Prasad, V; Sargent, M; Khalil, H; York, A; Kuwabara, Y; Saviola, A; Alfieri, C; Hansen, K; Yutzey, K; Molkentin, J. Transforming growth factor β-dependent regulation of cardiomyocyte maturation. Journal of Molecular and Cellular Cardiology Plus. 2025; 12:100400.

Morikawa, Y; Kim, JH; Li, RG; Liu, L; Liu, S; Deshmukh, V; Hill, MC; Martin, JF. YAP Overcomes Mechanical Barriers to Induce Mitotic Rounding and Adult Cardiomyocyte Division. Circulation. 2025; 151:76-93.

Prabakaran, AD; Montecino-Morales, F; McFarland, K; Govindarajan, T; Durumutla, HB; Latimer, H; Akinborewa, O; Villa, C; Millay, DP; Quattrocelli, M. The human genetic variant rs6190 unveils Foxc1 and Arid5a as novel prometabolic targets of the glucocorticoid receptor in muscle. Science Advances. 2025; 11:eadw2593.

Prabakaran, AD; Quattrocelli, M. The human glucocorticoid receptor variant rs6190 protects the heart from metabolic stress. Journal of Molecular and Cellular Cardiology Plus. 2025; 12:100306.

Secchia, S; Beilinson, V; Chen, X; Gucwa, M; Denson, LA; Miraldi, ER; Weirauch, MT; Ikegami, K. Starvation activates ECM-remodeling gene transcription and putative enhancers in fibroblasts despite inducing quiescence. Cell Reports. 2025; 44:115896.

Singh, S; Singh, N; Chauhan, A; Koshta, K; Baby, S; Tiwari, R; Jagdale, PR; Kumar, M; Sharma, V; Singh, D; Srivastava, V. Prenatal arsenic exposure alters EZH2/H3K27me3 to induce RKIP/NF-kB/ERK1/2-mediated early-onset kidney disease in mouse offspring. Environmental Science and Pollution Research. 2025; 32:8498-8517.

Steimle, JD; Zhao, Y; Meng, F; Taylor, ME; Turaga, D; Adachi, I; Li, X; Martin, JF. Single-nuclei transcriptomics reveals TBX5-dependent targets in a patient with Holt-Oram syndrome. The Journal of Clinical Investigation. 2025; 135:e180670.

Uscategui Calderon, M; Spaeth, ML; Granitto, M; Gonzalez, BA; Weirauch, MT; Kottyan, LC; Yutzey, KE. GDF10 promotes rodent cardiomyocyte maturation during the postnatal period. Journal of Molecular and Cellular Cardiology. 2025; 201:16-31.

Wadding-Lee, CA; Makarewich, CA. Microproteins in Metabolism. Cells. 2025; 14:859.

Yamaguchi, H; Tran, LT; Bi, J; Urayama, A; Yutzey, KE; Mishina, Y; Komatsu, Y. Enhanced BMP signaling in cranial neural crest cells induces aberrant chondrogenesis by upregulating Tbx20 expression during craniofacial development. Biochemical and Biophysical Research Communications. 2025; 765:151834.