Publications

Agnew, EJ; Velayutham, N; Ortiz, GM; Alfieri, CM; Hortells, L; Moore, V; Riggs, KW; Baker, RS; Gibson, AM; Ponny, SR; et al. Scar Formation with Decreased Cardiac Function Following Ischemia/Reperfusion Injury in 1 Month Old Swine. Journal of Cardiovascular Development and Disease. 2020; 7:1-1.

Bround, MJ; Bers, DM; Molkentin, JD. A 20/20 view of ANT function in mitochondrial biology and necrotic cell death. Journal of Molecular and Cellular Cardiology. 2020; 144:A3-A13.

Cramer, AA W; Prasad, V; Eftestøl, E; Song, T; Hansson, KA; Dugdale, HF; Sadayappan, S; Ochala, J; Gundersen, K; Millay, DP. Nuclear numbers in syncytial muscle fibers promote size but limit the development of larger myonuclear domains. Nature Communications. 2020; 11.

Demonbreun, AR; Wyatt, EJ; Fallon, KS; Oosterbaan, CC; Page, PG; Hadhazy, M; Quattrocelli, M; Barefield, DY; McNally, EM. A gene-edited mouse model of limb-girdle muscular dystrophy 2C for testing exon skipping. DMM Disease Models and Mechanisms. 2020; 13:dmm040832-dmm040832.

Hansson, KA; Eftestøl, E; Bruusgaard, JC; Juvkam, I; Cramer, AW; Malthe-Sørenssen, A; Millay, DP; Gundersen, K. Myonuclear content regulates cell size with similar scaling properties in mice and humans. Nature Communications. 2020; 11.

Holowiecki, A; Linstrum, K; Ravisankar, P; Chetal, K; Salomonis, N; Waxman, JS. Pbx4 limits heart size and fosters arch artery formation by partitioning second heart field progenitors and restricting proliferation. Development (Cambridge). 2020; 147:dev185652-dev185652.

Hortells, L; Valiente-Alandi, I; Thomas, ZM; Agnew, EJ; Schnell, DJ; York, AJ; Vagnozzi, RJ; Meyer, EC; Molkentin, JD; Yutzey, KE. A specialized population of Periostin-expressing cardiac fibroblasts contributes to postnatal cardiomyocyte maturation and innervation. Proceedings of the National Academy of Sciences of USA. 2020; 117:21469-21479.

Huo, J; Lu, S; Kwong, JQ; Bround, MJ; Grimes, KM; Sargent, MA; Brown, ME; Davis, ME; Bers, DM; Molkentin, JD. MCUb induction protects the heart from postischemic remodeling. Circulation Research. 2020; 127:379-390.

Kim, AJ; Xu, N; Umeyama, K; Hulin, A; Ponny, SR; Vagnozzi, RJ; Green, EA; Hanson, P; McManus, BM; Nagashima, H; et al. Deficiency of Circulating Monocytes Ameliorates the Progression of Myxomatous Valve Degeneration in Marfan Syndrome. Circulation. 2020; 141:132-146.

Makarewich, CA. The hidden world of membrane microproteins. Experimental Cell Research. 2020; 388:111853-111853.

Makarewich, CA; Bezprozvannaya, S; Gibson, AM; Bassel-Duby, R; Olson, EN. Gene therapy with the DWORF micropeptide attenuates cardiomyopathy in mice. Circulation Research. 2020; 127:1340-1342.

O'Donnell, A; Yutzey, KE. To EndoMT or Not to EndoMT: Zebrafish Heart Valve Development. Circulation Research. 2020; 126:985-987.

O'Donnell, A; Yutzey, KE. Mechanisms of heart valve development and disease. Development (Cambridge). 2020; 147:dev183020-dev183020.

Perl, E; Waxman, JS. Retinoic Acid Signaling and Heart Development. Sub-Cellular Biochemistry. 2020; 95:119-149.

Petrany, M; Swoboda, C; Sun, C; Chetal, K; Chen, X; Weirauch, M; Salomonis, N; Millay, D. Single-nucleus RNA-seq identifies transcriptional heterogeneity in multinucleated skeletal myofibers. 2020.

Petrany, MJ; Song, T; Sadayappan, S; Millay, DP. Myocyte-derived Myomaker expression is required for regenerative fusion but exacerbates membrane instability in dystrophic myofibers. JCI insight. 2020; 5.

Petrany, MJ; Swoboda, CO; Sun, C; Chetal, K; Chen, X; Weirauch, MT; Salomonis, N; Millay, DP. Single-nucleus RNA-seq identifies transcriptional heterogeneity in multinucleated skeletal myofibers. Nature Communications. 2020; 11.

Qi, L; Zang, H; Wu, W; Nagarkatti, P; Nagarkatti, M; Liu, Q; Robbins, J; Wang, X; Cui, T. CYLD exaggerates pressure overload-induced cardiomyopathy via suppressing autolysosome efflux in cardiomyocytes. Journal of Molecular and Cellular Cardiology. 2020; 145:59-73.

Reid, AL; Wang, Y; Samani, A; Hightower, RM; Lopez, MA; Gilbert, SR; Ianov, L; Crossman, DK; Dell'Italia, LJ; Millay, DP; et al. DOCK3 is a dosage-sensitive regulator of skeletal muscle and Duchenne muscular dystrophy-associated pathologies. Human Molecular Genetics. 2020; 29:2855-2871.

Schriever, SC; Kabra, DG; Pfuhlmann, K; Baumann, P; Baumgart, EV; Nagler, J; Seebacher, F; Harrison, L; Irmler, M; Kullmann, S; et al. Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity. Journal of Clinical Investigation. 2020; 130:6093-6108.

Vagnozzi, RJ; Maillet, M; Sargent, MA; Khalil, H; Johansen, AK Z; Schwanekamp, JA; York, AJ; Huang, V; Nahrendorf, M; Sadayappan, S; et al. An acute immune response underlies the benefit of cardiac stem cell therapy. Nature. 2020; 577:405-409.

Vagnozzi, RJ; Molkentin, JD. Resident macrophages keep mitochondria running in the heart. Cell Research. 2020; 30:1057-1058.

Vagnozzi, RJ; Sargent, MA; Molkentin, JD. Cardiac Cell Therapy Rejuvenates the Infarcted Rodent Heart via Direct Injection but Not by Vascular Infusion. Circulation. 2020; 141:1037-1039.

Velayutham, N; Alfieri, CM; Agnew, EJ; Riggs, KW; Baker, RS; Ponny, SR; Zafar, F; Yutzey, KE. Cardiomyocyte cell cycling, maturation, and growth by multinucleation in postnatal swine. Journal of Molecular and Cellular Cardiology. 2020; 146:95-108.

Weinberger, T; Esfandyari, D; Messerer, D; Percin, G; Schleifer, C; Thaler, R; Liu, L; Stremmel, C; Schneider, V; Vagnozzi, RJ; et al. Ontogeny of arterial macrophages defines their functions in homeostasis and inflammation. Nature Communications. 2020; 11.

Xu, N; Gulick, J; Osinska, H; Yu, Y; McLendon, PM; Shay-Winkler, K; Robbins, J; Yutzey, KE. Ube2v1 positively regulates protein aggregation by modulating ubiquitin proteasome system performance partially through K63 ubiquitination. Circulation Research. 2020; 126:907-922.

Yutzey, KE. Cytokinesis, beta-blockers, and congenital heart disease. The New England journal of medicine. 2020; 382:291-293.