Privette Vinnedge Lab


Wilcher, KE; Page, ER H; Privette Vinnedge, LM. The impact of the chromatin binding DEK protein in hematopoiesis and acute myeloid leukemia. Experimental Hematology. 2023; 123:18-27.

Singh, N; Romick-Rosendale, L; Watanabe-Chailland, M; Privette Vinnedge, LM; Komurov, K. Drug resistance mechanisms create targetable proteostatic vulnerabilities in Her2+ breast cancers. Editor, Dey N. PloS one. 2022; 17:e0256788.

Greene, AN; Solomon, MB; Privette Vinnedge, LM. Novel molecular mechanisms in Alzheimer's disease: The potential role of DEK in disease pathogenesis. Frontiers in Aging Neuroscience. 2022; 14:1018180.

Greene, AN; Nguyen, ET; Paranjpe, A; Lane, A; Privette Vinnedge, LM; Solomon, MB. In silico gene expression and pathway analysis of DEK in the human brain across the lifespan. European Journal of Neuroscience. 2022; 56:4720-4743.

Hegde, S; Gasilina, A; Wunderlich, M; Lin, Y; Buchholzer, M; Krumbach, OH F; Akbarzadeh, M; Ahmadian, MR; Seibel, W; Zheng, Y; Perentesis, JP; Mizukawa, BE; Vinnedge, LP; Cancelas, JA; Nassar, NN. Inhibition of the RacGEF VAV3 by the small molecule IODVA1 impedes RAC signaling and overcomes resistance to tyrosine kinase inhibition in acute lymphoblastic leukemia. Leukemia. 2022; 36:637-647.

Muhammad, B; Parks, LG; Komurov, K; Privette Vinnedge, LM. Defective transcription elongation in human cancers imposes targetable proteotoxic vulnerability. Translational Oncology. 2022; 16:101323.

Greene, AN; Parks, LG; Solomon, MB; Privette Vinnedge, LM. Loss of DEK Expression Induces Alzheimer's Disease Phenotypes in Differentiated SH-SY5Y Cells. Frontiers in Molecular Neuroscience. 2020; 13:594319.

Pease, NA; Shephard, MS; Sertorio, M; Waltz, SE; Vinnedge, LM P. DEK Expression in Breast Cancer Cells Leads to the Alternative Activation of Tumor Associated Macrophages. Cancers. 2020; 12:E1936.

Gasilina, A; Premnauth, G; Gurjar, P; Biesiada, J; Hegde, S; Milewski, D; Ma, G; Kalin, TV; Merino, E; Meller, J; Seibel, W; Cancelas, JA; Vinnedge, LP; Nassar, NN. IODVA1, a guanidinobenzimidazole derivative, targets Rac activity and Ras-driven cancer models. Editor, Lebedeva IV. PloS one. 2020; 15:e0229801.

Nassar, N; Hegde, SN; Gasilina, A; Wunderlich, M; Premnauth, G; Merino, E; Lin, Y; Ahmadian, R; Zheng, Y; Mizukawa, B; Privette Vinnedge, L; Cancelas, JA. The Small Molecule IODVA1 Inhibits the Rac Guanine Nucleotide Exchange Factor Vav3 and Overcomes TKI-Resistance in Ph+(BCR-ABL1) B-ALL. Blood. 2019; 134:4647.

Wen, Y; Xu, HN; Privette Vinnedge, L; Feng, M; Li, LZ. Optical Redox Imaging Detects the Effects of DEK Oncogene Knockdown on the Redox State of MDA-MB-231 Breast Cancer Cells. Molecular Imaging and Biology. 2019; 21:410-416.