Privette Vinnedge Lab

Hegde, S; Gasilina, A; Wunderlich, M; Lin, Y; Buchholzer, M; Krumbach, OH F; Akbarzadeh, M; Ahmadian, MR; Seibel, W; Zheng, Y; et al. Inhibition of the RacGEF VAV3 by the small molecule IODVA1 impedes RAC signaling and overcomes resistance to tyrosine kinase inhibition in acute lymphoblastic leukemia. Leukemia. 2021.

Greene, AN; Parks, LG; Solomon, MB; Privette Vinnedge, LM. Loss of DEK Expression Induces Alzheimer's Disease Phenotypes in Differentiated SH-SY5Y Cells. Frontiers in Molecular Neuroscience. 2020; 13.

Pease, NA; Shephard, MS; Sertorio, M; Waltz, SE; Vinnedge, LM P. DEK Expression in Breast Cancer Cells Leads to the Alternative Activation of Tumor Associated Macrophages. Cancers. 2020; 12.

Gasilina, A; Premnauth, G; Gurjar, P; Biesiada, J; Hegde, S; Milewski, D; Ma, G; Kalin, TV; Merino, E; Meller, J; et al. IODVA1, a guanidinobenzimidazole derivative, targets Rac activity and Ras-driven cancer models. PLoS ONE. 2020; 15.

Nassar, N; Hegde, SN; Gasilina, A; Wunderlich, M; Premnauth, G; Merino, E; Lin, Y; Ahmadian, R; Zheng, Y; Mizukawa, B; et al. The Small Molecule IODVA1 Inhibits the Rac Guanine Nucleotide Exchange Factor Vav3 and Overcomes TKI-Resistance in Ph+(BCR-ABL1) B-ALL. Blood. 2019; 134:4647-4647.

Wen, Y; Xu, HN; Privette Vinnedge, L; Feng, M; Li, LZ. Optical Redox Imaging Detects the Effects of DEK Oncogene Knockdown on the Redox State of MDA-MB-231 Breast Cancer Cells. Molecular Imaging and Biology. 2019; 21:410-416.

O'Donovan, SM; Franco-Villanueva, A; Ghisays, V; Caldwell, JL; Haroutunian, V; Privette Vinnedge, LM; McCullumsmith, RE; Solomon, MB. Sex differences in DEK expression in the anterior cingulate cortex and its association with dementia severity in schizophrenia. Schizophrenia Research. 2018; 202:188-194.

Modur, V; Singh, N; Mohanty, V; Chung, E; Muhammad, B; Choi, K; Chen, X; Chetal, K; Ratner, N; Salomonis, N; et al. Defective transcription elongation in a subset of cancers confers immunotherapy resistance. Nature Communications. 2018; 9.

Serrano-Lopez, J; Nattamai, K; Pease, NA; Shephard, MS; Wellendorf, AM; Sertorio, M; Smith, EA; Geiger, H; Wells, SI; Cancelas, JA; et al. Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors. Experimental Hematology. 2018; 59:40-50.e3.

Ghisays, V; Nguyen, ET; Streicher, J; Pease, NA; Fitzgerald, M; Estrada, CM; Franco-Villanueva, A; Privette Vinnedge, L; Solomon, MB. Neuroanatomical Distribution of DEK Protein in Corticolimbic Circuits Associated with Learning and Memory in Adult Male and Female Mice. Neuroscience. 2018; 371:254-267.

Wise-Draper, T; Sendilnathan, A; Palackdharry, S; Pease, N; Qualtieri, J; Butler, R; Sadraei, NH; Morris, JC; Patil, Y; Wilson, K; et al. Decreased plasma DEK Oncogene Levels Correlate with p16-Negative Disease and Advanced Tumor Stage in a Case-Control Study of Patients with Head and Neck Squamous Cell Carcinoma. Translational Oncology. 2018; 11:168-174.

Smith, EA; Gole, B; Willis, NA; Soria, R; Starnes, LM; Krumpelbeck, EF; Jegga, AG; Ali, AM; Guo, H; Meetei, AR; et al. DEK is required for homologous recombination repair of DNA breaks. Scientific Reports. 2017; 7.