Ongoing studies in the Center for Translational Fibrosis Research are designed to advance our understanding and treatment of organ fibrosis through diagnostic, therapeutic and discovery approaches.
A key limitation to treating fibrosis is inability to accurately detect fibrosis. Cutting edge studies in both non-invasive imaging (e.g. magnetic resonance imaging) and novel diagnostics aim to develop new diagnostic approaches for fibrosis.
There is currently a paucity of effective therapeutic approaches for fibrosis in any organ. Ongoing studies are testing novel therapeutics identified by CTFR investigators for their ability to attenuate or possibly even reverse organ fibrosis.
To advance mechanistic understanding of fibrosis and to identify new diagnostic and therapeutic targets, ongoing studies explore organ fibrosis at the single cell and gene expression level coupled with advanced screening, medicinal chemistry and drug development.