Neurofibromatosis OPG / Low Grade Glioma
Neurofibromatosis OPG / Low Grade Glioma
A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma
- Ages: ≥2 years of age to ≤ 21 years of age
This phase III trial studies if selumetinib works just as well as the standard treatment with carboplatine/vincristine (CV) for subjects with NF1-associated low grade glioma (LGG), and to see if selumetinib is better than CV in improving vision in subjects with LGG of the optic pathway (vision nerve ...More
APEC1621: Pediatric MATCH: Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders
- Ages: 12 Months to 21 Years
PURPOSE: This screening and multi-sub-study phase II trial studies how well treatment that is directed by genetic testing works in pediatric patients with solid tumors, non-Hodgkin lymphomas, or histiocytic disorders that have progressed following at least one line of standard systemic therapy and/o ...More
Contact Us
To learn more about available clinical trials related to brain and spinal tumors, contact us at cancer@cchmc.org or 513-636-2799.
Related Studies
- Medulloblastoma New Diagnosis
- Medulloblastoma Relapse / Refractory
- Low Grade Glioma New Diagnosis
- Low Grade Glioma Relapse / Refractory
- DIPG/High Grade Glioma New Diagnosis
- DIPG/High Grade Glioma Relapse / Refractory
- Ependymoma New Diagnosis
- Ependymoma Relapse / Refractory
- Neurofibromatosis Sarcoma New Diagnosis
- Neurofibromatosis Sarcoma Relapse / Refractory
- Neurofibromatosis NF2
- Neurofibromatosis Plexiform Neurofibroma
- Neurofibromatosis Other
- ATRT
- Craniopharyngioma
- Germ Cell Tumor
- Choroid Plexus Tumor
- All Other Brain and Spinal Tumors
3333 Burnet Avenue, Cincinnati, Ohio 45229-3026
© 1999-2025 Cincinnati Children's Hospital Medical Center. All rights reserved.
