Brain and Spinal Tumors Research Studies

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Neurofibromatosis NF2

NF2: Open-label, Phase 2 Study of Bevacizumab in Children and Young Adults With Neurofibromatosis 2 and Progressive Vestibular Schwannomas That Are Poor Candidates for Standard Treatment With Surgery or Radiation

PURPOSE: To determine the hearing response rate at 24 weeks after treatment with bevacizumab for symptomatic vestibular schwannomas (VS) in children and young adults with NF2.
 DETAILED DESCRIPTION: PRIMARY OBJECTIVES: Subjects will be treated with open-label bevacizumab 10 mg/kg every 2 ...More

SEL-TH-1601: Phase 2 Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors

PURPOSE: In this research study the researchers want to learn more about the effects (both good and bad) the study drug selumetinib has on participants with neurofibromatosis type II (NF2) related tumor. The researchers are asking patients with NF2 related tumors to be in the study, because their he ...More