Cystic Fibrosis Center
Cystic Fibrosis Center

Get expert cystic fibrosis care, advanced treatments and coordinated support from one of the nation’s top-ranked pediatric pulmonary programs.

A patient being treated with vest therapy.

Helping Children with Cystic Fibrosis Breathe Easier and Live Healthier

A cystic fibrosis (CF) diagnosis can feel overwhelming. Families often have questions about breathing problems, nutrition, infections and long-term health. At Cincinnati Children’s Cystic Fibrosis Center, we help families understand what comes next and create a clear plan for care.

Our team treats children with cystic fibrosis, CFTR-related disorders and complex lung infections using the latest evidence-based therapies. This includes CFTR modulators, airway clearance therapies and nutritional support. The center is also home to the Cystic Fibrosis Non-Tuberculous Mycobacterium (CF-NTM) Clinic, a comprehensive clinic specifically focused on providing NTM treatment to children with CF.

Why Choose Cincinnati Children’s Cystic Fibrosis Center?

  • Team-based care brings pulmonary, nutrition, gastroenterology, endocrinology, behavioral medicine and other specialists together for coordinated care.
  • Innovative treatments and research give families access to advanced therapies, remote monitoring studies and emerging CF treatments.
  • Personalized care plans are tailored to how each child responds to treatment, helping improve lung health, nutrition and daily life.
  • Whole-child support programs address mental health, school challenges, physical activity and quality of life alongside medical treatment.

Cystic Fibrosis Expertise, Centered on Your Child

Nationally Ranked Pulmonary Care

Cincinnati Children's is ranked No. 3 in the nation for pediatric pulmonology in the U.S. News & World Report 2026-2027 Best Children's Hospitals rankings. Our hospital has also been ranked as one of the best children’s hospitals for 20 years by U.S News & World Report. We are also accredited by the Cystic Fibrosis Foundation and recognized with the Cystic Fibrosis Foundation Quality of Care Award.

Families across the region trust our pulmonary team for expert care and ongoing support.

 Advanced Therapies and Research

Our team offers advanced cystic fibrosis treatments designed to improve lung function, nutrition and overall health. We provide evidence-based therapies including CFTR modulators, mucolytics and airway clearance treatments.

Cincinnati Children's is one of only 10 specially-designated CF Foundation Research Centers in the United States. We were one of the first care centers to join the CF Foundation's Therapeutics Development Network, and continue to support the full spectrum of CF drug development.

We also lead and participate in innovative research studies. Current work includes remote patient monitoring, theratyping research for patients who may respond to targeted therapies, and advanced imaging using Xe-MRI technology that monitors lung disease without radiation exposure. 

Coordinated, Team-Based Care

Children with cystic fibrosis often need care from many specialists. Our team-based care model helps families receive coordinated support from pulmonary medicine, gastroenterology, endocrinology, behavioral medicine, Otolaryngology (ENT) and lung transplant experts.

This coordinated approach creates one clear treatment plan while reducing stress for families. We also work closely with referring providers and local physicians to support ongoing care closer to home when possible.

Personalized Support for Every Child

Every child experiences cystic fibrosis differently. We build personalized care plans based on each child’s symptoms, goals and response to treatment.

Our whole-child programs, including BETTER-CF and CF-WELL, support emotional health, school success, physical activity and daily well-being alongside medical care.

Families also receive guidance from experienced providers starting at diagnosis. After a positive newborn screening result, families connect directly with our nurse practitioner for education, support, scheduling and answers to important questions.