Multidisciplinary Liver Tumor Research
Cincinnati Children’s is a major center for pediatric cancer research. Our researchers in the Liver Tumor Program lead and participate in numerous clinical research studies, with the goal of improving the prognosis and quality of life for patients with liver tumors.
Some of these studies are sponsored by Cincinnati Children’s, and some are offered at our site through national cooperative research organizations such as the Children’s Oncology Group and the National Cancer Institute’s Pediatric Phase I Consortium.
Physicians and researchers at Cincinnati Children’s play a leading role in many national and international clinical research studies. The Liver Tumor Program co-directors, James Geller, MD, and Greg Tiao, MD, also serve as co-chairs for the COG international study of pediatric liver cancer (AHEP-1531). This level of engagement in research ensures that patients have access to the most innovative and effective cancer treatments.
The Liver Tumor Research Group at Cincinnati Children’s includes members from oncology, pediatric surgery, hepatology, pathology, radiology and genetics. The group is conducting research in the following areas:
- Tumor formation, development and biological characteristics
- Advanced diagnostics and classification
- Genetic predisposition and tumor-specific genetics
- Molecular target identification
- Personalized (precision medicine) therapy
- Radiographic correlations to therapy
- Clinical therapy correlations and outcomes
National Referral Center
Cincinnati Children’s is a major referral center for clinical care and research for the Children’s Oncology Group, the National Cancer Institute’s new Pediatric Phase I Consortium and other national cancer research consortia. We are the only site in Ohio, and one of just a few nationwide, to offer pediatric Phase I clinical trials of the newest cancer therapies.