Cincinnati Children’s is a major center for pediatric cancer research. Our researchers in the Liver Tumor Program within the Cancer and Blood Diseases Institute probe cancer cells to understand how the disease develops and spreads, and they are finding targets for new anticancer drugs.

Physicians and researchers lead and participate in numerous clinical research studies, with the goal of improving the prognosis and quality of life for patients with liver tumors. Some of these studies are sponsored by Cincinnati Children’s, and some are offered at our site through national cooperative research organizations. These include the Children’s Oncology Group, which operates the nation’s largest portfolio of clinical trials for pediatric cancer, and the National Cancer Institute’s new Pediatric Phase I Consortium. Our membership in these exclusive consortia gives patients access to the latest clinical trials.

The Liver Tumor Research Group at Cincinnati Children’s includes members from oncology, pediatric surgery, hepatology, pathology, radiology and genetics. The group is conducting research in the following areas:

  • Tumor formation, development and biological characteristics
  • Advanced diagnostics and classification 
  • Genetic predisposition and tumor-specific genetics
  • Molecular target identification 
  • Personalized (precision medicine) therapy
  • Radiographic correlations to therapy
  • Clinical therapy correlations and outcomes

National Referral Center

Physicians and researchers at Cincinnati Children’s play a leading role in many national and international clinical research studies. We are a major referral center for clinical care and research for the Children’s Oncology Group, the National Cancer Institute’s new Pediatric Phase I Consortium and other national cancer research consortia. Many of our physicians serve in leadership positions for these organizations.

We are the only site in Ohio, and one of just a few nationwide, to offer pediatric Phase I clinical trials of the newest cancer therapies. This level of engagement in research ensures that patients have access to the most innovative and effective cancer treatments.