The Division of Nephrology and Hypertension at Cincinnati Children's has had a long-standing interest in the relationship between the human complement system and immune-mediated renal disease. Founded by complement biology pioneer Dr. Clark West, our Clinical Laboratory provides a number of measurements helpful in the diagnosis and management of the glomerulonephritides, complement deficiencies, iron deficiency, the dysgammaglobulinemias, immunoglobulin subclass deficiencies, systemic lupus erythematosus, therapy-induced immune deficiencies, and hereditary angioedema.

One focus of the Clinical Laboratory born out of the expertise in complement-mediated renal diseases is clinical testing for the thrombotic microangiopathies (TMA), specifically atypical hemolytic uremic syndrome (aHUS) and thrombotic thrombocytopenic purpura (TTP).

Our clinical lab technicians are certified by the American Society for Clinical Pathology (ASCP) and have a combined 35 years of experience in clinical testing. 

The Biomarker Laboratory 

The Nephrology Clinical Lab also partners with the Biomarker Laboratory to conduct front-line research into discovering diagnostic markers of disease that will lead to earlier and more accurate diagnoses, allowing physicians to better treat patients. 

The Biomarker Laboratory is housed in the Division of Nephrology and Hypertension and was born out of the shared discovery of neutrophil gelatinase-associated lipocalin (NGAL) as a promising new early diagnostic marker of kidney injury. Our goals are to usher pediatrics into the era of individualized medicine. In addition to original research into the discovery and validation of biomarkers of acute kidney injury and chronic kidney disease, the biomarker research laboratory assists investigators across Cincinnati Children's and around the globe in all stages of biomarker research as collaborations or fee for service, from pre-clinical discovery and assay development to validation in clinical trials. 


  • Clinical Lab: 513-636-4530
  • Clinical Lab results: 513-636-4281
  • Clinical Lab processing: 513-636-7355
  • Pager: 513-736-4617
  • Fax: 513-803-5056


Mailing Address

Cincinnati Children's Hospital Medical Center
Division of Nephrology and Hypertension
MLC 7022
3333 Burnet Ave.
Cincinnati, OH 45229-3039