Pursuing New Sarcoma Therapies Through Research
Clinical trials and lab-based research at Cincinnati Children’s are improving the prognosis and quality of life for patients with sarcoma. Our physicians, consulting specialists, nurses, support staff and laboratory scientists work together to pioneer new treatments for patients here and around the world. It’s reassuring to know that you are entrusting your child to a team that is passionate about developing new therapies that make difference in patient’s lives—including your child’s life.
An Extensive Portfolio of Clinical Research Trials
We offer a large number of clinical research trials. These trials provide patients early access to new anticancer therapies. Such advanced treatments may become a lifesaving option for patients whose sarcoma does not respond to therapy or returns after treatment.
Many of these studies are available through our partnerships with key institutions, such as the Children’s Oncology Group, Sarcoma Alliance for Research Through Collaboration, Children’s Oncology Group (COG) and Pediatric Early Phase Clinical Trials Network (PEP-CTN). Our physicians also team up with drug companies to develop novel therapies that are offered through clinical trials.
Breaking New Ground with Lab-Based Research
Scientists at Cincinnati Children’s are making exciting discoveries in the lab about what causes sarcoma. They’re also learning how to treat sarcoma more effectively. For example, in 2022, our team led a study that helps reveal why treatment works for some people with Ewing sarcoma but not for others. We learned outcomes can vary depending on specific tumor traits. Our discoveries could help cancer doctors develop more targeted care for people with Ewing sarcoma. Many of our patients donated biopsy samples to the study, playing a vital role to help us better understand this disease.
Our basic research program has other focus areas as well. For example, we’re learning more about the biology and potential therapies for osteosarcoma, rhabdomyosarcoma and neurofibromatosis-related cancers. Lab discoveries continue to push the science forward toward more effective treatments.
