Research is a vital aspect of the Sarcoma Program, and our physicians and researchers conduct numerous clinical research studies in hopes of improving the prognosis and quality of life for patients with tumors of the bone and soft tissue. This leading-edge research provides our patients with early access to new anticancer therapies, sometimes years before these therapies become widely available.

Researchers at Cincinnati Children’s developed many of the studies we offer. Others come to us through national institutions such as the Sarcoma Alliance for Research Collaboration and Children’s Oncology Group. Cincinnati Children’s physicians serve in leadership positions within these research organizations, further strengthening our link to the latest clinical research opportunities.

> Learn more about clinical research trials at Cincinnati Children’s.

Laboratory-Based Research

Researchers at Cincinnati Children’s also pursue laboratory-based research to better understand what causes sarcomas and collaborate with sarcoma specialists to develop new therapies. Current lab research efforts focus on:

  • Learning more about the biology and potential therapies for osteosarcoma and neurofibromatosis-related cancers, including malignant peripheral nerve sheath tumors
  • Investigating new cell-signaling pathways in rhabdomyosarcoma
  • Studying the role of transcription factors in alveolar rhabdomyosarcoma
  • Learning more about the biology and therapeutic targeting of EYA proteins in Ewing sarcoma

> Learn more about our world-class research on cancer in the Division of Oncology.