A photo of Henry Akinbi.

Henry T. Akinbi, MD

  • Attending Neonatologist, Neonatology and Pulmonary Biology
  • Member, Perinatal Institute
  • Professor, UC Department of Pediatrics

About

Biography

As a neonatologist, my clinical specialty is neonatology with specific interests in neonatal infections and blood transfusions. My research areas include toxicology, pharmacometrics and microbiome.

My research is a natural extension of my clinical practice because it promotes evidence-based diagnoses and therapy. One of my goals is to understand the role of early antibiotic exposure on the overall health of neonates. My research aims to increase our understanding and rationale for managing neonatal abstinence syndrome.

One of my accomplishments is the provision of a webinar for the College of Clinical Pharmacologists. My work has been published in several well-respected journals, including the Journal of Clinical Pharmacology, BMJ Open Quality, Scientific Reports, Journal of Parenteral and Enteral Nutrition, Pediatrics, Journal of Pediatrics and Journal of Immunology.

I have been with Cincinnati Children’s for more than 26 years. Collaborations with clinicians and non-clinicians are welcome.

MD: University of Ife, Ile-Ife, Nigera, Africa, 1980.

Residency: Pediatrics, University of North Carolina at Chapel Hill, 1988-1991.

Neonatology Fellowship: Children's Hospital of Philadelphia, Philadelphia, PA, 1991-1994.

Certification: General Pediatrics, 1991; Recertification, 1998; Newborn Medicine, 1995; Recertification, 2002.

Interests

Neonatal infections; blood transfusions

Services and Specialties

Neonatology, Perinatal

Interests

Pharmacokinetis/pharmacodynamics of psychotropic medications in neonates; role of lysozyme in airway host defense

Research Areas

Neonatology, Pulmonary Biology, Developmental Biology

Additional Languages

French

Publications

Selected

Suggestions for Model-Informed Precision Dosing to Optimize Neonatal Drug Therapy. Euteneuer, JC; Kamatkar, S; Fukuda, T; Vinks, AA; Akinbi, HT. Journal of Clinical Pharmacology. 2019; 59:168-176.

A review of pregnancy-induced changes in opioid pharmacokinetics, placental transfer, and fetal exposure: Towards fetomaternal physiologically-based pharmacokinetic modeling to improve the treatment of neonatal opioid withdrawal syndrome. van Hoogdalem, MW; Wexelblatt, SL; Akinbi, HT; Vinks, AA; Mizuno, T. Pharmacology and Therapeutics, Part A: Chemotherapy, Toxicology and. 2021.

Utility of Repeat Testing for Congenital Hypothyroidism in Infants with Very Low Birth Weight. Rose, SR; Blunden, CE; Jarrett, OO; Kaplan, K; Caravantes, R; Akinbi, HT. Journal of Pediatrics. 2021.

Opioid Treatment for Neonatal Opioid Withdrawal Syndrome: Current Challenges and Future Approaches. McPhail, BT; Emoto, C; Butler, D; Fukuda, T; Akinbi, H; Vinks, AA. Journal of Clinical Pharmacology. 2021; 61:857-870.

Impact of Institutional Breastfeeding Support in Very Low-Birth Weight Infants. Ward, LP; Tonnis, R; Otuneye, AT; Clemens, N; Akinbi, H; Morrow, AL. Breastfeeding Medicine. 2021; 16:238-244.

Physiologic Indirect Response Modeling to Describe Buprenorphine Pharmacodynamics in Newborns Treated for Neonatal Opioid Withdrawal Syndrome. Mizuno, T; McPhail, BT; Kamatkar, S; Wexelblatt, S; Ward, L; Christians, U; Akinbi, HT; Vinks, AA. Clinical Pharmacokinetics. 2021; 60:249-259.

Pharmacotherapy of neonatal opioid withdrawal syndrome: a review of pharmacokinetics and pharmacodynamics. van Hoogdalem, MW; McPhail, BT; Hahn, D; Wexelblatt, SL; Akinbi, HT; Vinks, AA; Mizuno, T. Expert Opinion on Drug Metabolism and Toxicology. 2021; 17:87-103.

Surfactant phospholipids act as molecular switches for premature induction of quorum sensing-dependent virulence in Pseudomonas aeruginosa. Kuang, Z; Bennett, RC; Lin, J; Hao, Y; Zhu, L; Akinbi, HT; Lau, GW. Virulence. 2020; 11:1090-1107.

Epidemiological Investigation on the Current Practice of Umbilical Cord Clamping in China. Zhu, J; Xie, Y; Wang, B; Wang, Y; Akinbi, H; Xie, L. American Journal of Perinatology. 2020.

Utilizing Pediatric Physiologically Based Pharmacokinetic Models to Examine Factors That Contribute to Methadone Pharmacokinetic Variability in Neonatal Abstinence Syndrome Patients. McPhail, BT; Emoto, C; Fukuda, T; Butler, D; Wiles, JR; Akinbi, H; Vinks, AA. Journal of Clinical Pharmacology. 2020; 60:453-465.

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