Henry T. Akinbi, MD
- Attending Neonatologist, Neonatology and Pulmonary Biology
- Member, Perinatal Institute
- Professor, UC Department of Pediatrics
- henry.akinbi@cchmc.org
- Board Certified
About
Biography
As a neonatologist, my clinical specialty is neonatology with specific interests in neonatal infections and blood transfusions. My research areas include toxicology, pharmacometrics and microbiome.
My research is a natural extension of my clinical practice because it promotes evidence-based diagnoses and therapy. One of my goals is to understand the role of early antibiotic exposure on the overall health of neonates. My research aims to increase our understanding and rationale for managing neonatal abstinence syndrome.
One of my accomplishments is the provision of a webinar for the College of Clinical Pharmacologists. My work has been published in several well-respected journals, including the Journal of Clinical Pharmacology, BMJ Open Quality, Scientific Reports, Journal of Parenteral and Enteral Nutrition, Pediatrics, Journal of Pediatrics and Journal of Immunology.
I have been with Cincinnati Children’s for more than 26 years. Collaborations with clinicians and non-clinicians are welcome.
MD: University of Ife, Ile-Ife, Nigera, Africa, 1980.
Residency: Pediatrics, University of North Carolina at Chapel Hill, 1988-1991.
Neonatology Fellowship: Children's Hospital of Philadelphia, Philadelphia, PA, 1991-1994.
Certification: General Pediatrics, 1991; Recertification, 1998; Newborn Medicine, 1995; Recertification, 2002.
Interests
Neonatal infections; blood transfusions
Services and Specialties
Neonatology, Perinatal
Interests
Pharmacokinetis/pharmacodynamics of psychotropic medications in neonates; role of lysozyme in airway host defense
Research Areas
Neonatology, Developmental Biology
Additional Languages
FrenchPublications
Suggestions for Model-Informed Precision Dosing to Optimize Neonatal Drug Therapy. Journal of Clinical Pharmacology. 2019; 59:168-176.
Antibiotic exposure prevents acquisition of beneficial metabolic functions in the preterm infant gut microbiome. Microbiome. 2022; 10:103.
Identifying the essential knowledge and skills for Neonatal-Perinatal Medicine: a systematic analysis of practice. Journal of Perinatology. 2022; 42:1266-1270.
Epidemiological Investigation on the Current Practice of Umbilical Cord Clamping in China. American Journal of Perinatology: neonatal and maternal-fetal medicine. 2022; 39:1015-1019.
A review of pregnancy-induced changes in opioid pharmacokinetics, placental transfer, and fetal exposure: Towards fetomaternal physiologically-based pharmacokinetic modeling to improve the treatment of neonatal opioid withdrawal syndrome. Pharmacology and Therapeutics. 2022; 234:108045.
Utility of Repeat Testing for Congenital Hypothyroidism in Infants with Very Low Birth Weight. The Journal of Pediatrics. 2022; 242:152-158.e1.
Physiologically-Based Pharmacokinetic Modeling to Investigate the Effect of Maturation on Buprenorphine Pharmacokinetics in Newborns with Neonatal Opioid Withdrawal Syndrome. Clinical Pharmacology and Therapeutics. 2022; 111:496-508.
Opioid Treatment for Neonatal Opioid Withdrawal Syndrome: Current Challenges and Future Approaches. Journal of Clinical Pharmacology. 2021; 61:857-870.
Impact of Institutional Breastfeeding Support in Very Low-Birth Weight Infants. Breastfeeding Medicine. 2021; 16:238-244.
Physiologic Indirect Response Modeling to Describe Buprenorphine Pharmacodynamics in Newborns Treated for Neonatal Opioid Withdrawal Syndrome. Clinical Pharmacokinetics. 2021; 60:249-259.
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