Spectroscopist, Imaging Research Center
Professor, UC Department of RadiologyUC Department of Pediatrics
Kim M. Cecil, PhD, received her undergraduate and postgraduate training in chemistry. After a post-doctoral fellowship in magnetic resonance spectroscopy and imaging at the Hospital of the University of Pennsylvania, Dr. Cecil joined the Department of Radiology and the Imaging Research Center at Cincinnati Children’s Hospital Medical Center in 1998. She serves as an imaging research scientist and clinical MR spectroscopist.
In 2000, Kim M. Cecil, PhD, Antonius deGrauw, MD, PhD, and Gajja Salomons, PhD, discovered creatine transporter deficiency syndrome, a genetic disorder caused by mutations in the creatine transporter gene (SLC6A8). Male patients demonstrate a significant reduction or absence of creatine in the brain, as indicated by MR spectroscopy. This is an X-linked intellectual disability disorder thought to be second only to fragile X in prevalence.
Magnetic resonance spectroscopy; creatine deficiency syndromes
Magnetic resonance imaging and spectroscopy; inborn errors of metabolism; environmental exposures to lead manganese, air pollution, PBDEs, PFCs; traumatic brain injury including concussion; ADHD; bipolar disorders; breast cancer; non-alcoholic fatty liver disease
Kim M. Cecil, PhD1/24/2020
BS: Chemistry & Mathematics (magna cum laude), Kentucky Wesleyan College, 1988.
MS: Chemistry, Vanderbilt University, 1991.
PhD: Chemistry, Vanderbilt University, 1993.
Fellowship: Hospital of the University of Pennsylvania, Philadelphia, PA.
Myo-inositol mediates the effects of traffic-related air pollution on generalized anxiety symptoms at age 12 years.
Brunst, KJ; Ryan, PH; Altaye, M; Yolton, K; Maloney, T; Beckwith, T; LeMasters, G; Cecil, KM.
Big GABA II: Water-referenced edited MR spectroscopy at 25 research sites.
Mikkelsen, M; Rimbault, DL; Barker, PB; Bhattacharyya, PK; Brix, MK; Buur, PF; Cecil, KM; Chan, KL; Chen, DY-T; Craven, AR; et al.
Diagnostic methods and recommendations for the cerebral creatine deficiency syndromes.
Clark, JF; Cecil, KM.
Pediatric Sports-Related Concussion Produces Cerebral Blood Flow Alterations.
Maugans, TA; Farley, C; Altaye, M; Leach, J; Cecil, KM.
Proton Magnetic Resonance Spectroscopy in Adults with Childhood Lead Exposure.
Cecil, KM; Dietrich, KN; Altaye, M; Egelhoff, JC; Lindquist, DM; Brubaker, CJ; Lanphear, BP.
Environmental Health Perspectives.
The influence of age of lead exposure on adult gray matter volume.
Brubaker, CJ; Dietrich, KN; Lanphear, BP; Cecil, KM.
Altered myelination and axonal integrity in adults with childhood lead exposure: A diffusion tensor imaging study.
Brubaker, CJ; Schmithorst, VJ; Haynes, EN; Dietrich, KN; Egelhoff, JC; Lindquist, DM; Lanphear, BP; Cecil, KM.
Decreased brain volume in adults with childhood lead exposure.
Cecil, KM; Brubaker, CJ; Adler, CM; Dietrich, KN; Altaye, M; Egelhoff, JC; Wessel, S; Elangovan, I; Hornung, R; Jarvis, K; et al.
The impact of early childhood lead exposure on brain organization: A functional magnetic resonance imaging study of language function.
Yuan, W; Holland, SK; Cecil, KM; Dietrich, KN; Wessel, SD; Altaye, M; Hornung, RW; Ris, MD; Egelhoff, JC; Lanphear, BP.
Children With Dyslexia and Typical Readers: Sex-Based Choline Differences Revealed Using Proton Magnetic Resonance Spectroscopy Acquired Within Anterior Cingulate Cortex.
Horowitz-Kraus, T; Brunst, KJ; Cecil, KM.
Frontiers in Human Neuroscience.
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