A photo of Kimberly Yolton.

Director of Research Section, General and Community Pediatrics

Professor, UC Department of Pediatrics

513-636-2815

Biography & Affiliation

Biography

As a developmental psychologist and epidemiologist, I’m interested in exposures and experiences that may alter a child’s developmental trajectory from infancy through adolescence. I collaborate on research projects on typical child development as well as those focused on the impact of exposures to environmental toxicants, opiates and stress during early development.

Early in my research, I studied prenatal exposure to drugs like cocaine and opiates on infant and child neurobehavioral outcomes, and then I discovered the impact that tobacco smoke can have on a child’s health and development. Studying tobacco smoke led to exploration of other environmental toxicants like metals, industrial chemicals and air pollution. I always balance my studies by accounting for other factors, such as stress, poverty and caregiver characteristics as they are also critical contributors to a child’s development.

Through a pregnancy and birth cohort study from Cincinnati, we have studied a variety of common environmental toxicants — tobacco smoke, air pollution, pesticides and industrial chemicals — and how they may impact child neurobehavior, health and neuroimaging outcomes. We completed our most recent follow-up on the children in 2019, at age 12. We are awaiting funding decisions that will extend our follow-up to late adolescence.

I also collaborate with investigators from multiple institutions, both domestically and internationally, regarding neurobehavioral assessments and staff training strategies. We work to acquire the most appropriate outcome measures with the highest standards of reliability and validity. My ultimate goal is to identify short- and long-term neurobehavioral outcomes among infants and children from a variety of samples, advancing our understanding of developmental trajectories and factors that may alter outcomes.

As director of research for the Division of General and Community Pediatrics, I interact with researchers of all levels, providing support and guidance as they plan their projects. I am associate director of our National Research Service Award Fellowship in General Pediatrics, and I serve as training faculty on three T32 fellowship grants and for the Medical Scientist Training Program. I also hold a secondary appointment at the University of Cincinnati College of Medicine in the Department of Environmental and Public Health Sciences. These roles allow me to interact with medical students, graduate students, postdoctoral fellows and faculty, providing mentorship and research guidance.

I have been a researcher for more than 28 years and started working at Cincinnati Children’s in 2000. Some highlights of my research career include:

  • Our longitudinal pregnancy and birth cohort continues to follow children of pregnant women who were enrolled in the study in 2003-2006 and has resulted in more than 100 scientific publications.
  • We were the first to describe associations between exposure to secondhand smoke and disturbances to child sleep. We were also among the first to describe associations between exposure to secondhand smoke and deficits in reading, math and problem-solving abilities in children.
  • I was involved in the development of the Neonatal Intensive Care Unit (NICU) Network Neurobehavioral Scale (NNNS), a specialized assessment tool for evaluating early infant neurobehavior. This test is often used with neonates in prenatal drug exposure studies. I have used it extensively in studying the impact of prenatal exposure to environmental toxicants, finding different patterns of neurobehavioral outcomes in relation to a variety of different exposures. I regularly conduct training sessions on the proper uses of this tool and the newly released NNNS-II.
  • I have been involved in follow-up studies of high-risk infants directed by the NICHD-funded Neonatal Research Network (NRN) for more than 25 years.
  • I received the Senior Research Achievement Award at Cincinnati Children’s in 2019.

Research Interests

Infant and child development and behavior; environmental exposures

Academic Affiliation

Professor, UC Department of Pediatrics

Divisions

General and Community Pediatrics



Blog Posts

Plastics and Pesticides: Tracking Down the Real Risks

Community Health

Plastics and Pesticides: Tracking Down the Real Risks

Kimberly Yolton, PhD6/25/2019

Pregnant Women Should Eat Fish

BlogHealthy Living

Pregnant Women Should Eat Fish

By Kimberly Yolton, PhD5/23/2016

Education

PhD: Family Relations & Human Development, Developmental Psychology, The Ohio State University, Columbus, OH, 1992.

Fellowship: Pediatric Environmental Health, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2000-2003.

Publications

Selected Publication

Early infant attention as a predictor of social and communicative behavior in childhood. Bowers, K; Khoury, J; Sucharew, H; Xu, Y; Chen, A; Lanphear, B; Yolton, K. International Journal of Behavioral Development. 2019; 43:204-211.

Cohort Profile: The Health Outcomes and Measures of the Environment (HOME) study. Braun, JM; Kalloo, G; Chen, A; Dietrich, KN; Liddy-Hicks, S; Morgan, S; Xu, Y; Yolton, K; Lanphear, BP. International Journal of Epidemiology. 2017; 46:dyw006-dyw006.

Prenatal Polybrominated Diphenyl Ether Exposures and Neurodevelopment in U.S. Children through 5 Years of Age: The HOME Study. Chen, A; Yolton, K; Rauch, SA; Webster, GM; Hornung, R; Sjoedin, A; Dietrich, KN; Lanphear, BP. Environmental Health Perspectives. 2014; 122:856-862.

Exposure to neurotoxicants and the development of attention deficit hyperactivity disorder and its related behaviors in childhood. Yolton, K; Cornelius, M; Ornoy, A; McGough, J; Makris, S; Schantz, S. Neurotoxicology and Teratology. 2014; 44:30-45.

Low-level prenatal exposure to nicotine and infant neurobehavior. Yolton, K; Khoury, J; Xu, Y; Succop, P; Lanphear, B; Bernert, JT; Lester, B. Neurotoxicology and Teratology. 2009; 31:356-363.

Environmental Tobacco Smoke Exposure and Child Behaviors. Yolton, K; Khoury, J; Hornung, R; Dietrich, K; Succop, P; Lanphear, B. Journal of Developmental and Behavioral Pediatrics. 2008; 29:450-457.

Principles and practices of neurodevelopmental assessment in children: Lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. Dietrich, KN; Eskenazi, B; Schantz, S; Yolton, K; Rauh, VA; Johnson, CB; Alkon, A; Canfield, RL; Pessah, IN; Berman, RF. Environmental Health Perspectives. 2005; 113:1437-1446.

Low-level environmental lead exposure and children's intellectual function: An international pooled analysis. Lanphear, BP; Hornung, R; Khoury, J; Yolton, K; Baghurstl, P; Bellinger, DC; Canfield, RL; Dietrich, KN; Bornschein, R; Greene, T; et al. Environmental Health Perspectives. 2005; 113:894-899.

Exposure to environmental tobacco smoke and cognitive abilities among US children and adolescents. Yolton, K; Dietrich, K; Auinger, P; Lanphear, BP; Hornung, R. Environmental Health Perspectives. 2005; 113:98-103.

Associations Between Early Low-Level Tobacco Smoke Exposure and Executive Function at Age 8 Years. Oh, K; Xu, Y; Terrizzi, BF; Lanphear, B; Chen, A; Kalkbrenner, AE; Yolton, K. The Journal of Pediatrics. 2020; 221:174-180.e1.