Photo of { Kelli C. Dominick, MD, PhD}

Kelli C. Dominick, MD, PhD


  • Psychiatrist, Division of Child and Adolescent Psychiatry
  • Medical Director, Interventional Psychiatry
  • Associate Program Director of Research, Child and Adolescent Psychiatry Fellowship and Triple Board Residency Program
  • Associate Professor, UC Department of Psychiatry and Behavioral Neuroscience

About

Biography

I am a child and adolescent psychiatrist specializing in the care of children, adolescents and young adults with complex psychiatric and neurodevelopmental needs, particularly in the context of autism spectrum disorder, intellectual disability, fragile X syndrome, Phelan-McDermid syndrome, Down syndrome and other neurodevelopmental and genetic conditions.

My clinical work focuses on catatonia, neurodevelopmental regression, severe mood and behavioral symptoms, and complex psychiatric presentations that can be challenging to diagnose or manage. I work closely with families and multidisciplinary teams to understand changes in behavior, movement, mood, communication and functioning, and to develop thoughtful, individualized treatment plans.

I serve as medical director of interventional psychiatry and director of the Neurobehavioral Catatonia Clinic at Cincinnati Children’s. I am also a member of the Phelan-McDermid Syndrome Clinic, where I focus on psychiatric and neurobehavioral evaluation, treatment planning and collaboration with interdisciplinary providers.

In addition to my clinical work, I am actively engaged in research and education focused on neurodevelopmental disorders, catatonia, regression and complex psychiatric presentations. My research collaborations include work with the Shaffer Lab and Cincinnati Children’s SPARK team to better understand neuropsychiatric symptoms and clinical trajectories in autism and related neurodevelopmental conditions. As associate program director for research education in the child and adolescent psychiatry fellowship and triple board residency programs, I mentor fellows in research design, evidence-based practice and scholarly development.

MD, PhD: Boston University School of Medicine, Boston, MA, 2011

Residency: Pediatrics / Adult Psychiatry / Child Psychiatry, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2016

Certifications: Child and Adolescent Psychiatry; Adult Psychiatry

Interests

Neurodevelopmental disorders, including autism spectrum disorder, intellectual disability, fragile X syndrome, Phelan-McDermid syndrome and Down syndrome; catatonia; neurodevelopmental regression; severe mood and behavioral symptoms; interventional psychiatry

Services and Specialties

Interests

Catatonia, neurodevelopmental regression, and complex psychiatric symptoms in neurodevelopmental and genetic conditions; autism spectrum disorder and related neurodevelopmental disorders; clinical trajectories and barriers to diagnosis; interventional psychiatry implementation; multidisciplinary care models; research education

Insurance Information

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Publications

Gaboxadol increases resting theta and alpha power without affecting evoked responses in fragile X syndrome in a home-based setting. De Stefano, LA; Kim, H; Erickson, CA; Schmitt, LM; Dominick, KC; Pedapati, EV; Huckle, R; Wilson, R; Mckinney, WS; Reisinger, DL; Nelson, MN; Dapore, AE; Horn, PS; Miyakoshi, M. Journal of Neurodevelopmental Disorders. 2026; 18(1).

Safety and Efficacy of Paliperidone Palmitate in Pediatric Patients with Autism and Intellectual Disability. Simpson, S; Dominick, KC; Erickson, CA; Lamy, M. Journal of Autism and Developmental Disorders. 2026; 56(5):2077-2083.

Acute and chronic dosing of the GABA A alpha 2,3 selective agonist BAER-101 do not alter behavior but may impact auditory-evoked EEG responses in adults with fragile X syndrome. De Stefano, LA; Kim, H; Erickson, CA; Pedapati, EV; Dominick, KC; Shaffer, R; Wink, LK; Schmitt, LM; Miyakoshi, M. Scientific Reports. 2026; 16(1).

Brief Report: Differences Between Stanford-Binet Abbreviated and Full-Scale Estimates of IQ in Fragile X Syndrome Vary Across Development. Mckinney, WS; Nelson, M; Shaffer, RC; Dominick, KC; Erickson, CA; Schmitt, LM. Journal of Autism and Developmental Disorders. 2025.

Is Pediatric Catatonia on the Rise? Soe, KC; Arnold, MJ; Smith, JR; Dominick, KC. Hospital pediatrics. 2025; 15(9):e449-e452.

Safety and Effectiveness of Clozapine in Youth and Young Adults with Neurodevelopmental Disorders and Severe, Treatment-Refractory Irritability and Aggression: A Retrospective Chart Review. Harris, K; Fosdick, C; Zappia, KJ; Dominick, KC; Lamy, M. Journal of Child and Adolescent Psychopharmacology. 2025; 35(6):337-346.

Patterns in Medication Use for Treatment of Depression in Autistic Spectrum Disorder. Argonis, RA; Pedapati, EV; Dominick, KC; Harris, K; Lamy, M; Fosdick, C; Schmitt, L; Shaffer, RC; Smith, E; Will, M; Mcdougle, CJ; Erickson, CA. Journal of Autism and Developmental Disorders. 2025; 55(6):1969-1975.

Results from a Double-Blind, Randomized, Placebo-Controlled, Single-Dose, Crossover Trial of Lovastatin or Minocycline in Fragile X Syndrome. Mckinney, WS; Schmitt, LM; De Stefano, LA; Ethridge, L; Norris, JE; Horn, PS; Dauterman, S; Rosselot, H; Pedapati, EV; Reisinger, DL; Friedman, NR; Hong, M; Sweeney, JA; Erickson, C. Journal of Child and Adolescent Psychopharmacology. 2025; 35(4):211-221.

Frontal cortex hyperactivation and gamma desynchrony in Fragile X syndrome: Correlates of auditory hypersensitivity. Pedapati, EV; Ethridge, LE; Liu, Y; Liu, R; Sweeney, JA; Destefano, LA; Miyakoshi, M; Razak, K; Schmitt, LM; Moore, DR; Dominick, KC; Horn, PS; Binder, D; Erickson, CA. PLoS ONE. 2025; 20(5):e0306157.

Beyond the Fragile X protein: neighborhood characteristics explain individual differences in IQ and adaptive behaviors of Fragile X syndrome. Mckinney, WS; Corsmeier, A; Dapore, A; Gross, C; Dominick, KC; Erickson, CA; Schmitt, LM. Frontiers in Psychiatry. 2025; 16:1636987.

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