A photo of Elif Erkan.

Pediatric Nephrologist, Division of Nephrology

Associate Professor, UC Department of Pediatrics

513-636-4531

Board Certified

My Biography & Research

Biography

Dr. Elif Erkan received the prestigious SPR Fellow's Basic Research Award upon completion of her pediatric nephrology fellowship. She pursued a career as a physician scientist and continued to investigate the mechanism of proteinuria induced injury in proximal tubule cells following her fellowship. Her laboratory demonstrated an important link between endocytic adapter protein disabled-2 (Dab2) that binds to the cytoplasmic tail of albumin receptor megalin and protein kinase B (Akt). She received an NIH career development-KO8 award to support her studies elucidating the link between albumin endocytosis and cell signaling events.

Clinical Interests

Proteinuria; nephrotic syndrome.

Research Interests

Proteinuria induced tubular injury; tubular apoptosis; albumin endocytosis.

Academic Affiliation

Associate Professor, UC Department of Pediatrics

Departments

Nephrology and Hypertension, Nephrology and Hypertension

My Locations

My Education

MD: Ankara University School of Medicine, Ankara, Turkey, 1990.

Residency: Pediatrics, Marmara University Hospital, Istanbul, Turkey, 1992-1997.

Residency: Pediatrics, Montefiore Medical Center, Albert Einstein School of Medicine, Bronx, NY, 2000-2002.

Fellowship: Pediatric Nephrology, Montefiore Medical Center, Albert Einstein School of Medicine, Bronx, NY, 1997-2000.

MS: Clinical Research Methods Montefiore Medical Center, Albert Einstein School of Medicine, Bronx, NY, 1998-2001.

My Publications

Health-related quality of life in glomerular disease. Canetta, PA; Troost, JP; Mahoney, S; Kogon, AJ; Carlozzi, N; Bartosh, SM; Cai, Y; Davis, TK; Fernandez, H; Fornoni, A; et al. Kidney International. 2019; 95:1209-1224.

CureGN Study Rationale, Design, and Methods: Establishing a Large Prospective Observational Study of Glomerular Disease. Mariani, LH; Bomback, AS; Canetta, PA; Flessner, MF; Helmuth, M; Hladunewich, MA; Hogan, JJ; Kiryluk, K; Nachman, PH; Nast, CC; et al. American Journal of Kidney Diseases. 2019; 73:218-229.

Distinct urinary lipid profile in children with focal segmental glomerulosclerosis. Erkan, E; Zhao, X; Setchell, K; Devarajan, P. Pediatric Nephrology. 2016; 31:581-588.

Akt Links Insulin Signaling to Albumin Endocytosis in Proximal Tubule Epithelial Cells. Coffey, S; Costacou, T; Orchard, T; Erkan, E. PLoS ONE. 2015; 10:e0140417-e0140417.

Akt recruits Dab2 to albumin endocytosis in the proximal tubule. Koral, K; Li, H; Ganesh, N; Birnbaum, MJ; Hallows, KR; Erkan, E. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 2014; 307:F1380-F1389.