A photo of Michelle Eckerle.

Michelle D. Eckerle, MD

  • Attending Physician, Emergency Department
  • Assistant Professor, UC Department of Pediatrics



I’m an attending physician, researcher and educator who specializes in emergency medicine, sepsis and global health. I’m also the program director for the pediatric emergency medicine fellowship.

I was drawn to the field of emergency medicine because it provides an opportunity to interact with patients and families across the spectrum of ages and illnesses. I enjoy partnering with my colleagues to assess and stabilize the sickest children who present in the emergency room at Cincinnati Children’s, as well as helping to train future pediatric emergency medicine physicians.

My interest in global health stems from my experiences working in sub-Saharan Africa. I’m passionate about making sure that evidence-based care is accessible in both low- and high-income countries.

In addition to studying global health initiatives, my research focuses on sepsis and acute respiratory illness. Here in the U.S., I aim to improve the accuracy of assessing children who may have sepsis. Internationally, I seek to understand the pathophysiology of critical illness in low-income countries and identify whether recommended interventions are indeed beneficial to children in these settings.


Post-COVID-19 Conditions Among Children 90 Days After SARS-CoV-2 Infection. Funk, AL; Kuppermann, N; Florin, TA; Tancredi, DJ; Xie, J; Kim, K; Finkelstein, Y; Neuman, MI; Salvadori, MI; Yock-Corrales, A; et al. JAMA Network Open. 2022; 5.

Prevalence of Cardiac Dysfunction in Malawian Children With Severe Febrile Illness. Bensman, RS; Berrens, Z; Mkaliainga, T; Banda, B; Puri, K; Sanyahumbi, A; Byczkowski, T; Eckerle, M. Pediatric Critical Care Medicine. 2022; 23:493-501.

Identifying modifiable risk factors for mortality in children aged 1-59 months admitted with WHO-defined severe pneumonia: a single-centre observational cohort study from rural Malawi. Eckerle, M; Mvalo, T; Smith, AG; Kondowe, D; Makonokaya, D; Vaidya, D; Hosseinipour, MC; McCollum, ED. BMJ Paediatrics Open. 2022; 6.

Outcomes of SARS-CoV-2-Positive Youths Tested in Emergency Departments: The Global PERN-COVID-19 Study. Funk, AL; Florin, TA; Kuppermann, N; Tancredi, DJ; Xie, J; Kim, K; Neuman, MI; Ambroggio, L; Plint, AC; Mintegi, S; et al. JAMA Network Open. 2022; 5.

Patterns of Vasoactive Agent Initiation Among Children With Septic Shock in the Pediatric Emergency Department. Jeffreys, KL; Eckerle, M; Depinet, H. Pediatric Emergency Care. 2022; 38:e205-e208.

Cardiovascular Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference. Alexander, PM A; Checchia, PA; Ryerson, LM; Bohn, D; Eckerle, M; Gaies, M; Laussen, P; Jeffries, H; Thiagarajan, RR; Shekerdemian, L; et al. Pediatrics. 2022; 149:S39-S47.

Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Contemporary Organ Dysfunction Criteria: Executive Summary. Bembea, MM; Agus, M; Akcan-Arikan, A; Alexander, P; Basu, R; Bennett, TD; Bohn, D; Brandão, LR; Brown, AM; Carcillo, JA; et al. Pediatrics. 2022; 149:S1-S12.

PRagMatic Pediatric Trial of Balanced vs nOrmaL Saline FlUid in Sepsis: study protocol for the PRoMPT BOLUS randomized interventional trial. Weiss, SL; Balamuth, F; Thompson, GC; Hayes, KL; Katcoff, H; Cook, M; Tsemberis, E; Hickey, CP; Williams, A; Williamson-Urquhart, S; et al. Trials. 2021; 22.

Relationship between distance of referring facilities and haemoglobin change in children in Malawi. Keating, EM; Robison, JA; Chiume, M; Taddie, M; VanDerslice, JA; Benson, LS; Fitzgerald, E; Crouse, HL; Eckerle, MD; Ciccone, EJ; et al. Paediatrics and international child health. 2021; 41:253-261.

Blood transfusion and mortality in children with severe anaemia in a malaria-endemic region. Keating, EM; Chiume, M; Fitzgerald, E; Mgusha, Y; Mvalo, T; Fino, N; Crouse, HL; Eckerle, M; Gorman, K; Ciccone, EJ; et al. Paediatrics and international child health. 2021; 41:129-136.

From the Blog

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Predictors of Severe Outcomes in Children with COVID-19

Michelle D. Eckerle, MD1/14/2022

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