A photo of Michelle Eckerle.

Michelle D. Eckerle, MD

  • Attending Physician, Emergency Department
  • Associate Director of Education, Division of Emergency Medicine
  • Assistant Professor, UC Department of Pediatrics



I’m an attending physician, researcher and educator who specializes in emergency medicine, sepsis and global health. I’m also the program director for the pediatric emergency medicine fellowship.

I was drawn to the field of emergency medicine because it provides an opportunity to interact with patients and families across the spectrum of ages and illnesses. I enjoy partnering with my colleagues to assess and stabilize the sickest children who present in the emergency room at Cincinnati Children’s, as well as helping to train future pediatric emergency medicine physicians.

My interest in global health stems from my experiences working in sub-Saharan Africa. I’m passionate about making sure that evidence-based care is accessible in both low- and high-income countries.

In addition to studying global health initiatives, my research focuses on sepsis and acute respiratory illness. Here in the U.S., I aim to improve the accuracy of assessing children who may have sepsis. Internationally, I seek to understand the pathophysiology of critical illness in low-income countries and identify whether recommended interventions are indeed beneficial to children in these settings.

MD: University of Louisville, Louisville, KY, 2002.

Residency: Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2005.

Certification: Pediatrics.

Services and Specialties

Emergency Medicine

Research Areas

Emergency Medicine


Association between positive blood culture and clinical outcomes among children treated for sepsis in the emergency department. Clemens, N; Wilson, PM; Lipshaw, MJ; Depinet, H; Zhang, Y; Eckerle, M. American Journal of Emergency Medicine. 2024; 76:13-17.

Impact of SARS-CoV-2 Infection on the Association Between Laboratory Tests and Severe Outcomes Among Hospitalized Children. Xie, J; Kuppermann, N; Florin, TA; Tancredi, DJ; Funk, AL; Kim, K; Salvadori, MI; Yock-Corrales, A; Shah, NP; Breslin, KA; et al. Open Forum Infectious Diseases. 2023; 10:ofad485.

Mortality by Admission Diagnosis in Children 1-60 Months of Age Admitted to a Tertiary Care Government Hospital in Malawi. Choi, JH; Tanner, TE; Eckerle, MD; Chen, JS; Ciccone, EJ; Bell, GJ; Ngulinga, FF; Nkosi, E; Bensman, RS; Crouse, HL; et al. American Journal of Tropical Medicine and Hygiene. 2023; 109:443-449.

Strengthening Pediatric Global Health Fellowship Programs: Process Toward Accreditation. Bauserman, M; Crouse, H; Steenhoff, AP; Vinograd, AM; Robison, JA; Batra, M; Cohn, KA; Eckerle, M. Pediatrics. 2023; 152:e2023061283.

Antibiotic treatment failure in children aged 1 to 59 months with World Health Organization-defined severe pneumonia in Malawi: A CPAP IMPACT trial secondary analysis. Mvalo, T; Smith, AG; Eckerle, M; Hosseinipour, MC; Kondowe, D; Vaidya, D; Liu, Y; Corbett, K; Nansongole, D; Mtimaukanena, TA; et al. PloS one. 2022; 17:e0278938.

A Call to Action for Standardizing Letters of Recommendation. Tavarez, MM; Baghdassarian, A; Bailey, J; Caglar, D; Eckerle, M; Fang, A; McVety, K; Nagler, J; Ngo, TL; Rose, JA; et al. Journal of graduate medical education. 2022; 14:642-646.

Post-COVID-19 Conditions Among Children 90 Days After SARS-CoV-2 Infection. Funk, AL; Kuppermann, N; Florin, TA; Tancredi, DJ; Xie, J; Kim, K; Finkelstein, Y; Neuman, MI; Salvadori, MI; Yock-Corrales, A; et al. JAMA Network Open. 2022; 5:e2223253.

Prevalence of Cardiac Dysfunction in Malawian Children With Severe Febrile Illness. Bensman, RS; Berrens, Z; Mkaliainga, T; Banda, B; Puri, K; Sanyahumbi, A; Byczkowski, T; Eckerle, M. Pediatric Critical Care Medicine. 2022; 23:493-501.

Identifying modifiable risk factors for mortality in children aged 1-59 months admitted with WHO-defined severe pneumonia: a single-centre observational cohort study from rural Malawi. Eckerle, M; Mvalo, T; Smith, AG; Kondowe, D; Makonokaya, D; Vaidya, D; Hosseinipour, MC; McCollum, ED. BMJ Paediatrics Open. 2022; 6:e001330.

Outcomes of SARS-CoV-2-Positive Youths Tested in Emergency Departments: The Global PERN-COVID-19 Study. Funk, AL; Florin, TA; Kuppermann, N; Tancredi, DJ; Xie, J; Kim, K; Neuman, MI; Ambroggio, L; Plint, AC; Mintegi, S; et al. JAMA Network Open. 2022; 5:e2142322.

From the Blog

Predictors of Severe Outcomes in Children with COVID-19
Infectious Diseases and Vaccines

Predictors of Severe Outcomes in Children with COVID-19

Michelle D. Eckerle, MD1/14/2022

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