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Associate Professor, UC Department of Pediatrics

513-636-3366

Biography & Affiliation

Academic Affiliation

Associate Professor, UC Department of Pediatrics

Department

Developmental Biology

Education

BS: University of Wisconsin, Milwaukee, WI, 1994.

PhD: Mayo Graduate School, Rochester, MN, 2000.

Postdoctoral Fellow: Molecular mechanisms of Hox specificity in Drosophila melanogaster, Columbia University.

Publications

A Comprehensive Structure-Function Study of Neurogenin3 Disease-Causing Alleles during Human Pancreas and Intestinal Organoid Development. Zhang, X; McGrath, PS; Salomone, J; Rahal, M; McCauley, HA; Schweitzer, J; Kovall, R; Gebelein, B; Wells, JM. Developmental Cell. 2019; 50:367-380.e7.

The cis-regulatory logic underlying abdominal Hox-mediated repression versus activation of regulatory elements in Drosophila. Zandvakili, A; Uhl, JD; Campbell, I; Salomone, J; Song, YC; Gebelein, B. Developmental Biology. 2019; 445:226-236.

Degenerate Pax2 and Senseless binding motifs improve detection of low-affinity sites required for enhancer specificity. Zandvakili, A; Campbell, I; Gutzwiller, LM; Weirauch, MT; Gebelein, B. PLoS Genetics. 2018; 14:e1007289-e1007289.

Control of species-dependent cortico-motoneuronal connections underlying manual dexterity. Gu, Z; Kalamboglas, J; Yoshioka, S; Han, W; Li, Z; Kawasawa, YI; Pochareddy, S; Li, Z; Liu, F; Xu, X; et al. Science. 2017; 357:400-404.

A Hox complex activates and potentiates the Epidermal Growth Factor signaling pathway to specify Drosophila oenocytes. Wang, G; Gutzwiller, L; Li-Kroeger, D; Gebelein, B. PLoS Genetics. 2017; 13:e1006910-e1006910.

The Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and Force. Kovall, RA; Gebelein, B; Sprinzak, D; Kopan, R. Developmental Cell. 2017; 41:228-241.

Mechanisms of specificity for hox factor activity. Zandvakili, A; Gebelein, B. Journal of Developmental Biology. 2016; 4:16-16.

A Hox Transcription Factor Collective Binds a Highly Conserved Distal-less cis-Regulatory Module to Generate Robust Transcriptional Outcomes. Uhl, JD; Zandvakili, A; Gebelein, B. PLoS Genetics. 2016; 12:e1005981-e1005981.

Rhomboid Enhancer Activity Defines a Subset of Drosophila Neural Precursors Required for Proper Feeding, Growth and Viability. Gresser, AL; Gutzwiller, LM; Gauck, MK; Hartenstein, V; Cook, TA; Gebelein, B. PLoS ONE. 2015; 10:e0134915-e0134915.