I work with children and their families to form personalized care plans. Parents are the experts on their own child, and I want to help them take care of their child's lungs.

About

Biography

I love working with children — they are resilient, funny and brave. It's my goal to help children breathe well so they can live the life they want.

As a pediatric pulmonologist, I specialize in taking care of children with lung disease, including those with asthma, chronic cough, recurrent pneumonia and cystic fibrosis. I am a member of the Cystic Fibrosis Center at Cincinnati Children’s.

I work with children and their families to form personalized care plans. Parents are the experts on their own child, and I want to help them take care of their child's lungs.

In my research, I am interested in why cystic fibrosis lung disease severity is so variable from person to person. I am studying a chemical made in the body, called TGFbeta, which might worsen lung disease in certain people. Studying this chemical may help us discover new therapies to stop early lung damage in cystic fibrosis.

I am a recipient of the Procter Scholar Award, which supports highly promising junior faculty pursuing a career in academic research. My research has been supported by funding from the Cystic Fibrosis Foundation and Cystic Fibrosis Research, Inc.

When I’m not at work, I enjoy spending time with my husband and two daughters. We have lived in Cincinnati more than 15 years.

Location

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Publications

Sensitive structural and functional measurements and 1-year pulmonary outcomes in pediatric cystic fibrosis. Willmering, MM; Roach, DJ; Kramer, EL; Walkup, LL; Cleveland, ZI; Woods, JC. Journal of Cystic Fibrosis. 2021; 20:533-539.

Recombinant Acid Ceramidase Reduces Inflammation and Infection in Cystic Fibrosis. Gardner, AI; Haq, IJ; John Simpson, A; Becker, KA; Gallagher, J; Saint-Criq, V; Verdon, B; Mavin, E; Trigg, A; Gray, MA; et al. American Journal of Respiratory and Critical Care Medicine. 2020; 202:1133-1145.

Fibrocyte accumulation in the lungs of cystic fibrosis patients. Kasam, RK; Gajjala, PR; Jegga, AG; Courtney, JA; Randell, SH; Kramer, EL; Clancy, JP; Madala, SK. Journal of Cystic Fibrosis. 2020; 19:815-822.

Neutrophil extracellular traps activate IL-8 and IL-1 expression in human bronchial epithelia. Hudock, KM; Collins, MS; Imbrogno, M; Snowball, J; Kramer, EL; Brewington, JJ; Gollomp, K; McCarthy, C; Ostmann, AJ; Kopras, EJ; et al. American Journal of Physiology - Lung Cellular and Molecular Physiology. 2020; 319:L137-L147.

Data driven decision making to characterize clinical personas of parents of children with cystic fibrosis: a mixed methods study. Szczesniak, RD; Pestian, T; Duan, LL; Li, D; Stamper, S; Ferrara, B; Kramer, E; Clancy, JP; Grossoehme, D. BMC Pulmonary Medicine. 2020; 20.

Subacute TGFβ Exposure Drives Airway Hyperresponsiveness in Cystic Fibrosis Mice through the PI3K Pathway. Kramer, EL; Madala, SK; Hudock, KM; Davidson, C; Clancy, JP. American Journal of Respiratory Cell and Molecular Biology. 2020; 62:657-667.

Subacute TGFβ expression drives inflammation, goblet cell hyperplasia, and pulmonary function abnormalities in mice with effects dependent on CFTR function. Kramer, EL; Hardie, WD; Madala, SK; Davidson, C; Clancy, JP. American Journal of Physiology - Lung Cellular and Molecular Physiology. 2018; 315:L456-L465.

2045 The role of TGFβ in driving early cystic fibrosis lung disease. Kramer, EL; Hardie, W; Hudock, K; Davidson, C; Ostmann, A; Clancy, JP. Journal of Clinical and Translational Science. 2018; 2:33-33.

MicroRNA-145, Cystic Fibrosis Transmembrane Conductance Regulator, and Transforming Growth Factor-β. An (Un)tangled Regulatory Web. Kramer, EL; Clancy, JP. American Journal of Respiratory and Critical Care Medicine. 2018; 197:551-552.

Chronic β2AR stimulation limits CFTR activation in human airway epithelia. Brewington, JJ; Backstrom, J; Feldman, A; Kramer, EL; Moncivaiz, JO; Ostmann, AJ; Zhu, X; Lu, LJ; Clancy, JP. JCI insight. 2018; 3.

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