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Assistant Professor, UC Department of Pediatrics

513-636-6771

Board Certified

My Biography & Research

Biography

I love working with children — they are resilient, funny and brave. It's my goal to help children breathe well so they can live the life they want.

As a pediatric pulmonologist, I specialize in taking care of children with lung disease, including those with asthma, chronic cough, recurrent pneumonia and cystic fibrosis. I am a member of the Cystic Fibrosis Center at Cincinnati Children’s.

I work with children and their families to form personalized care plans. Parents are the experts on their own child, and I want to help them take care of their child's lungs.

In my research, I am interested in why cystic fibrosis lung disease severity is so variable from person to person. I am studying a chemical made in the body, called TGFbeta, which might worsen lung disease in certain people. Studying this chemical may help us discover new therapies to stop early lung damage in cystic fibrosis.

I am a recipient of the Procter Scholar Award, which supports highly promising junior faculty pursuing a career in academic research. My research has been supported by funding from the Cystic Fibrosis Foundation and Cystic Fibrosis Research, Inc.

When I’m not at work, I enjoy spending time with my husband and two daughters. We have lived in Cincinnati more than 15 years.

Academic Affiliation

Assistant Professor, UC Department of Pediatrics

Divisions

Pulmonary Medicine, Pulmonary Medicine

My Locations

My Education

PhD: University of Cincinnati, Cincinnati, OH, 2009.

MD: University of Cincinnati, Cincinnati, OH, 2011.

Residency: Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2014.

Fellowship: Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2016.

Certification: Pediatrics, 2014.

My Publications

Subacute TGF beta expression drives inflammation, goblet cell hyperplasia, and pulmonary function abnormalities in mice with effects dependent on CFTR function. Kramer, EL; Hardie, WD; Madala, SK; Davidson, C; Clancy, JP. American Journal of Physiology: Lung Cellular and Molecular Physiology. 2018; 315:L456-L465.

MicroRNA-145, Cystic Fibrosis Transmembrane Conductance Regulator, and Transforming Growth Factor-beta An (Un)tangled Regulatory Web. Kramer, EL; Clancy, JP. American Journal of Respiratory and Critical Care Medicine. 2018; 197:551-552.

Chronic beta 2AR stimulation limits CFTR activation in human airway epithelia. Brewington, JJ; Backstrom, J; Feldman, A; Kramer, EL; Moncivaiz, JO; Ostmann, AJ; Zhu, X; Lu, LJ; Clancy, JP. JCI insight. 2018; 3.

TGF beta as a therapeutic target in cystic fibrosis. Kramer, EL; Clancy, JP. Expert Opinion on Therapeutic Targets. 2018; 22:177-189.

Variable phenotype in a novel mutation in PHOX2B. Lombardo, RC; Kramer, E; Cnota, JF; Sawnani, H; Hopkin, RJ. American Journal of Medical Genetics, Part A. 2017; 173:1705-1709.

CFTR modulator therapies in pediatric cystic fibrosis: focus on ivacaftor. Kramer, EL; Clancy, JP. Expert Opinion on Orphan Drugs. 2016; 4:1033-1042.