A photo of James Leach.

James L. Leach, MD

  • Radiologist, Department of Radiology and Medical Imaging
  • Professor, UC Department of Radiology

About

Biography

James (Jim) Leach, MD, is a neuroradiologist specializing in pediatric neuroradiology at Cincinnati Children's Hospital Medical Center. He was chief resident in Radiology in 1994, and fellow in neuroradiology from 1995-1997 at the University of Cincinnati Medical Center where he was trained by Robert Lukin and Thomas Tomsick.

After serving as a staff neuroradiologist at the University of Cincinnati, Dr. Leach spent five years in private practice at Margaret Mary Community Hospital in Batesville, Indiana. Dr. Leach returned to the University of Cincinnati in 2003. He was program director for the Radiology Residency Program from 2003-2006. While at UC Dr. Leach was awarded the Harold B. Spitz Award in 1997 and 2004 for excellence in resident education. Dr. Leach began his full time career at Cincinnati Children's Hospital Medical Center in September 2007, focusing on pediatric neuroradiology. He was fellowship director of the Pediatric Neuroradiology fellowship from 2013-2017. He is currently a clinical professor of Radiology at the University of Cincinnati College of Medicine.

BS: Ohio University, Athens, OH, 1985.

MD: University of Cincinnati, Cincinnati, OH, 1990.

Residency: University Hospital, Cincinnati, OH, 1990-1994.

Fellowship: University Hospital, Cincinnati, OH, 1994-1996.

Certification: National Board of Medical Examiners, 1990; American Board of Radiology, 1994; Neuroradiology, 1997, 2007.

Interests

Neuroradiology; advanced imaging in epilepsy; functional MRI (fMRI), multimodal imaging of brain tumors; imaging of stroke; MRI utilization; quality assurance initiatives for neuroradiology interpretation

Services and Specialties

Radiology, Epilepsy, Brain Tumor, Hereditary Hemorrhagic Telangiectasia, Cerebrovascular, Sturge-Weber Syndrome

Interests

Neuroradiology; advanced imaging in epilepsy; functional MRI (fMRI), multimodal imaging of brain tumors; imaging of stroke; MRI utilization; quality assurance initiatives for neuroradiology interpretation

Research Areas

Radiology

Publications

Volumetric endpoints in diffuse intrinsic pontine glioma: comparison to cross-sectional measures and outcome correlations in the International DIPG/DMG Registry. Lazow, MA; Nievelstein, MT; Lane, A; Bandopadhayhay, P; DeWire-Schottmiller, M; Fouladi, M; Glod, JW; Greiner, RJ; Hoffman, LM; Hummel, TR; et al. Neuro-Oncology. 2022; 24:1598-1608.

Cerebral Arterial Growth in Childhood. Taylor, JM; Chang, M; Vaughan, J; Horn, PS; Zhang, B; Leach, JL; Vadivelu, S; Abruzzo, T. Pediatric Neurology. 2022; 134:59-66.

Responsive neurostimulation device therapy in pediatric patients with complex medically refractory epilepsy. Hartnett, SM; Greiner, HM; Arya, R; Tenney, JR; Aungaroon, G; Holland, K; Leach, JL; Air, EL; Skoch, J; Mangano, FT. Journal of Neurosurgery: Pediatrics. 2022; 1-8.

Neuronal Circuits Supporting Development of Visual Naming Revealed by Intracranial Coherence Modulations. Arya, R; Ervin, B; Buroker, J; Greiner, HM; Byars, AW; Rozhkov, L; Skoch, J; Horn, PS; Frink, C; Scholle, C; et al. Frontiers in Neuroscience. 2022; 16.

Accuracy of central neuro-imaging review of DIPG compared with histopathology in the International DIPG Registry. Lazow, MA; Fuller, C; Dewire, M; Lane, A; Bandopadhayay, P; Bartels, U; Bouffet, E; Cheng, S; Cohen, KJ; Cooney, TM; et al. Neuro-Oncology. 2022; 24:821-833.

Does central nervous system dysfunction underlie patellofemoral pain in young females? Examining brain functional connectivity in association with patient-reported outcomes. Diekfuss, JA; Grooms, DR; Nissen, KS; Coghill, RC; Bonnette, S; Barber Foss, KD; Dudley, JA; Berz, K; Logan, K; Gubanich, P; et al. Journal of Orthopaedic Research. 2022; 40:1083-1096.

Extraneural Metastases of Diffuse Midline Glioma, H3 K27M-Mutant at Diagnosis: Case Report, Review of the Literature, and Identifying Targetable Alterations. Lazow, MA; Leach, JL; Trout, AT; Breneman, JC; Fouladi, M; Fuller, C. Journal of Pediatric Hematology/Oncology. 2022; 44:e597-e604.

Phase I study of ribociclib and everolimus in children with newly diagnosed DIPG and high-grade glioma: A CONNECT pediatric neuro-oncology consortium report. Dewire, M; Lazow, M; Campagne, O; Leach, J; Fuller, C; Senthil Kumar, S; Stanek, J; De Blank, P; Hummel, TR; Pillay-Smiley, N; et al. Neuro-Oncology Advances. 2022; 4.

A pilot radiogenomic study of DIPG reveals distinct subgroups with unique clinical trajectories and therapeutic targets. Zhu, X; Lazow, MA; Schafer, A; Bartlett, A; Senthil Kumar, S; Mishra, DK; Dexheimer, P; DeWire, M; Fuller, C; Leach, JL; et al. Acta neuropathologica communications. 2021; 9.

A distributed network supports spatiotemporal cerebral dynamics of visual naming. Ervin, B; Buroker, J; Byars, AW; Rozhkov, L; Leach, JL; Horn, PS; Scholle, C; Mangano, FT; Greiner, HM; Holland, KD; et al. Electromyography and Clinical Neurophysiology. 2021; 132:2948-2958.

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