Photo of { Kyle McCracken, MD, PhD}

Kyle McCracken, MD, PhD


  • Member, Division of Nephrology and Hypertension
  • Member, Center for Stem Cell and Organoid Medicine (CuSTOM)
  • Associate Professor, UC Department of Pediatrics

About

BS: Xavier University, Cincinnati, OH, 2008

PhD: University of Cincinnati, Cincinnati, OH, 2014

MD: University of Cincinnati, Cincinnati, OH, 2016

Residency: Pediatrics, Boston Children's Hospital, Boston, MA, 2018

Fellowship: Pediatric Nephrology, Boston Children's Hospital, Boston, MA, 2022

Interests

Pediatric nephrology; inpatient nephrology

Services and Specialties

Interests

Kidney development; stem cell differentiation and organoids; tissue engineering and morphogenesis; kidney pathophysiology

Publications

Integrating collecting systems in human kidney organoids through fusion of distal nephron to ureteric bud. Shi, M; Crouse, B; Sundaram, N; Pode Shakked, N; Thorner, K; King, NM; Dutta, P; Ester, L; Zhang, W; Govindarajah, V; Mayhew, CN; Helmrath, MA; Bonventre, JV; Mccracken, KW. Cell Stem Cell. 2025; 32(7):1055-1070.e8.

Directed differentiation of ureteric bud and collecting duct organoids from human pluripotent stem cells. Shi, M; Fu, P; Bonventre, JV; Mccracken, KW. Nature Protocols. 2023; 18(8):2485-2508.

Human ureteric bud organoids recapitulate branching morphogenesis and differentiate into functional collecting duct cell types. Shi, M; Mccracken, KW; Patel, AB; Zhang, W; Ester, L; Valerius, MT; Bonventre, JV. Nature Biotechnology. 2023; 41(2):252-261.

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