Kyle McCracken, MD, PhD

A retinoic acid-Rfx6 cascade modulates Wnt/Bmp-dependent gut tube patterning: insight into the molecular basis of Mitchell-Riley Syndrome. Rankin, SA; Biesiada, J; Mccracken, KW; Patel, RK; Rana, M; Luedeke, DM; Kechele, DO; Wells, JM; Zorn, AM. Development. 2026; 153(18).

Mapping Alterations in Nephrogenesis Induced by Metabolic Stress. Shi, M; Mccracken, KW. Journal of the American Society of Nephrology. 2026; 37(9):1849-1851.

Single cell RNA sequencing reveals transitional states and signaling shifts in nephron progenitor cells of the late-gestation rhesus macaque kidney. Thakkar, K; Yarlagadda, S; Alkhudairy, L; Potter, A; Thorner, K; Chaturvedi, P; Cebrian, C; Mccracken, KW; Salomonis, N; Kopan, R; Schuh, MP. BMC Genomics. 2026; 27(1).

Reciprocal inhibition of Wnt signaling pathways pattern the interconnection of epithelial tubules in the regenerating zebrafish kidney. Kamei, CN; Sampson, WGB; Albertz, C; Aries, O; Wolf, A; Upadhyay, RM; Hughes, SM; Schenk, H; Bonnet, F; Draper, BBW; Mccracken, KW; Marciano, DK; Oxburgh, L; Drummond, IA. Development. 2026; 153(4).

Co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids. Miao, Y; Pek, NM; Tan, C; Jiang, C; Yu, Z; Iwasawa, K; Shi, M; Kechele, DO; Sundaram, N; Pastrana-Gomez, V; Zorn, AM; Chen, Y-W; Guo, M; Gu, M. Cell. 2025; 188(16):4295-4313.e27.

Integrating collecting systems in human kidney organoids through fusion of distal nephron to ureteric bud. Shi, M; Crouse, B; Sundaram, N; Pode Shakked, N; Thorner, K; King, NM; Dutta, P; Ester, L; Zhang, W; Govindarajah, V; Mayhew, CN; Helmrath, MA; Bonventre, JV; Mccracken, KW. Cell Stem Cell. 2025; 32(7):1055-1070.e8.

Vascular network-inspired diffusible scaffolds for engineering functional midbrain organoids. Cai, H; Tian, C; Chen, L; Yang, Y; Sun, AX; Mccracken, K; Tchieu, J; Gu, M; Mackie, K; Guo, F. Cell Stem Cell. 2025; 32(5):824-837.e5.

Müllerian Agenesis in a patient with Rubinstein-Taybi Syndrome: A Case Series and Review of the Overlapping Developmental Biologic Pathways. Roth, LP; Yu, LX; Johnson, J; Qu'd, D; Mccracken, K; Simpson, BN; Pennesi, CM. Journal of Pediatric and Adolescent Gynecology. 2024; 37(1):67-71.

RAAS-deficient organoids indicate delayed angiogenesis as a possible cause for autosomal recessive renal tubular dysgenesis. Pode-Shakked, N; Slack, M; Sundaram, N; Schreiber, R; Mccracken, KW; Dekel, B; Helmrath, M; Kopan, R. Nature Communications. 2023; 14(1):8159.

Directed differentiation of ureteric bud and collecting duct organoids from human pluripotent stem cells. Shi, M; Fu, P; Bonventre, JV; Mccracken, KW. Nature Protocols. 2023; 18(8):2485-2508.