Peter A. Margolis, MD, PhD

Professor, UC Department of Pediatrics

peter.margolis@cchmc.org
Board Certified

About

Biography

When I was in primary care practice, I observed how challenging it was to create health systems that effectively met patient and clinician needs. This observation shifted my focus toward engaging patients, clinicians and researchers to improve care together.

My research areas include quality improvement, health services research, and understanding the impact of health systems design on the outcomes of patients and communities.

I study systems improvement methods across a broad range of areas, including primary and subspecialty care, communities and public health settings. My goal is to organize healthcare as a continuous learning system that integrates clinical care, improvement methods and research to provide the best evidence for the decisions that patients and clinicians make.

I'm particularly interested in improving care for pediatric chronic illness. I am scientific director of the international ImproveCareNow network, which has grown to include more than 100 care sites serving children and adolescents with inflammatory bowel disease.

For my work, I have been elected as a member of the National Academy of Medicine.

Research Areas

Quality Improvement

Additional Languages

Italian, Spanish

Publications

The Test and Protect Program: A Data-Driven, Community-Engaged Approach to COVID-19 Testing Site Localization. Beck, AF; Mattingly, T; Brokamp, C; Sahay, R; Manning, ER; Taylor, S; Kuhnell, P; Kegley, B; Trabue, K; Margolis, PA; Kahn, RS; Hartley, DM. Journal of public health management and practice : JPHMP. 2025; 31:61-64.

A regional learning health system of congregate care facilities for COVID-19 response. Zafar, MA; Beck, AF; Chirumbolo, C; Wilson, KD; Haralson, K; Rich, K; Margolis, P; Hartley, D. Learning Health Systems. 2024; 8:e10407.

High Body Mass Index and Response to Anti-Tumor Necrosis Factor Therapy in Pediatric Crohn's Disease. Ebach, DR; Jester, TW; Galanko, JA; Firestine, AM; Ammoury, R; Cabrera, J; Bass, J; Minar, P; Olano, K; Margolis, P; Molle-Rios, Z; Saeed, SA; Bousvaros, A; Kappelman, MD. The American Journal of Gastroenterology (Elsevier). 2024; 119:1110-1116.

Conceptualizing and redefining successful patient engagement in patient advisory councils in learning health networks. Huwe, M; Woolf, B; David, J; Seid, M; Saeed, S; Margolis, P. Learning Health Systems. 2024; 8:e10377.

Electronic health records identify timely trends in childhood mental health conditions. Elia, J; Pajer, K; Prasad, R; Pumariega, A; Maltenfort, M; Utidjian, L; Shenkman, E; Kelleher, K; Rao, S; Margolis, PA; Christakis, DA; Hardan, AY; Ballard, R; Forrest, CB. Child and Adolescent Psychiatry and Mental Health. 2023; 17:107.

Racial Disparities in Pediatric Inflammatory Bowel Disease Care: Differences in Outcomes and Health Service Utilization Between Black and White Children. Smith, J; Liu, C; Beck, A; Fei, L; Brokamp, C; Meryum, S; Whaley, KG; Minar, P; Hellmann, J; Denson, LA; Margolis, P; Dhaliwal, J. The Journal of Pediatrics. 2023; 260:113522.

Comparative Effectiveness of Anti-TNF in Combination With Low-Dose Methotrexate vs Anti-TNF Monotherapy in Pediatric Crohn's Disease: A Pragmatic Randomized Trial. Kappelman, MD; Wohl, DA; Herfarth, HH; Firestine, AM; Adler, J; Ammoury, RF; Aronow, JE; Bass, DM; Bass, JA; Benkov, K; Zikry, M; Weinberger, M; Saeed, SA; Bousvaros, A. Gastroenterology. 2023; 165:149-161.e7.

780 ANTI-TNF IN COMBINATION WITH LOW DOSE METHOTREXATE OUTPERFORMS ANTI-TNF MONOTHERAPY IN PATIENTS WITH PEDIATRIC CROHN'S DISEASE INITIATING ADALIMUMAB BUT NOT INFLIXIMAB. Kappelman, M; Wohl, DA; Herfarth, H; Firestine, AM; Adler, J; Steiner, SJ; Colletti, RB; Park, KT; Grossman, AB; Ivanova, A; Weinberger, M; Margolis, P; Saeed, S; Bousvaros, A. Gastroenterology. 2023; 164:s-168.

A Bipolar Learning Health Network: An innovation whose time has come. Nierenberg, AA; Margolis, P; Strakowski, S; Trivedi, M; Yatham, LN; Blumberg, HP; DelBello, M; Duckworth, K; Gorrindo, T; Iosifescu, D; Tohen, M; Wisner, KL; Wozniak, J; Yurgelun-Todd, D. Bipolar Disorders: an international journal of psychiatry and neurosciences. 2023; 25:177-180.

Su1013 EVALUATION OF INSURANCE TYPE ON PRIOR AUTHORIZATION (PA) DELAYS IN PEDIATRIC INFLAMMATORY BOWEL DISEASE (IBD) PATIENTS PRESCRIBED BIOLOGIC THERAPIES. Smith, J; Howard, CA; Etter, R; Hellmann, J; Whaley, KG; Minar, PP; Denson, LA; Margolis, P; Dhaliwal, J. Gastroenterology. 2023; 164:s-504-s-505.

From the Blog

Infectious Diseases and Vaccines

PEDSnet Report Details How COVID-19 Pandemic Has Affected Children

Peter A. Margolis, MD, PhD, Nathan Pajor, MD ...11/23/2020

Quality and Safety

Learning Networks Multiply the Speed and Reach of Innovation

Peter A. Margolis, MD, PhD, Michael Seid, PhD6/27/2019