A photo of Peter Margolis.

Co-Director, James M. Anderson Center for Health Systems Excellence

Professor, UC Department of Pediatrics



My Biography & Research


Peter Margolis, MD, PhD, is the co-director of the James M. Anderson Center for Health System Excellence at Cincinnati Children’s Hospital Medical Center. His work encompasses the application and study of systems improvement methods across a broad range of areas including primary and sub-specialty care, communities and public health settings to improve the health outcomes of children, families and communities. Over the last 20 years, he and his research team have developed innovative approaches that engage patients, their families, clinicians, scientists and communities in developing network-based learning health systems that simultaneously improve care, spawn innovation and accelerate research. This work has repeatedly demonstrated significant impact on the process and outcomes of care. Dr. Margolis has worked extensively with the certifying boards and specialty societies to assist them in designing programs that will enable physicians to meet new Maintenance of Certification requirements focused on systems thinking and performance in practice. He was co-PI of an NIH Transformative Research Grant focused on developing learning health systems for children with chronic illness by harnessing the inherent motivation and expertise of all stakeholders involved. Dr. Margolis has extensive experience in large scale comparative effectiveness research, the creation of large scale interoperable data systems, managing large project teams and engaging individuals from diverse backgrounds to co-produce improved care and research. He is currently PI and Co-PI of two PCORnet networks (ImproveCareNow, PEDSnet). He also serves as chair of the PCORnet Council which is aimed at transforming research infrastructure in the US. Recently, the ImproveCareNow Network which he leads was awarded the Drucker Prize, the largest non-profit management and innovation award in the US.

Dr. Margolis obtained his MD from New York University and his pediatric training at the University of Colorado, where he also served as chief resident in pediatrics. He spent three years in the National Health Service Corps in Rochester, NY, and Los Angeles, CA before pursuing a fellowship in clinical epidemiology. He was a Robert Wood Johnson Clinical Scholar at the University of North Carolina at Chapel Hill where he also earned his PhD in Epidemiology. Dr. Margolis was also a Robert Wood Johnson Generalist Faculty Scholar at UNC.

Additional Languages

Italian, Spanish

Academic Affiliation

Professor, UC Department of Pediatrics


James M Anderson Center for Health Systems Excellence, Primary Care Offices, Interventional Radiology

My Education

MD: New York University School of Medicine, New York, NY, 1980.

PhD: University of North Carolina at Chapel Hill, Chapel Hill, NC, 1990.

Chief Resident: University of Colorado Health Sciences Center, Denver, CO, 1983-1984.

Resident: University of Colorado Health Sciences Center, Denver, CO, 1980-1983.

Certification: American Board of Pediatrics, 1985.

My Publications

Forrest CB, Crandall WV, Bailey LC, Zhang P, Joffe MM, Colletti RB, Adler J, Baron HI, Berman J, del Rosario F, Grossman AB, Hoffenberg EJ, Israel EJ, Kim SC, Lightdale JR, Margolis PA, Marsolo K, Mehta DI, Milov DE, Patel AS, Tung J, Kappelman MD. Effectiveness of anti-TNFα for Crohn disease: research in a pediatric learning health system. Pediatrics.  2014 Jul;134(1):37-44.

Forrest CB, Margolis PA, Bailey LC, Marsolo K, Del Beccaro MA, Finkelstein JA, Milov DE, Vieland VJ, Wolf BA, Yu FB, Kahn MG. PEDSnet: a National Pediatric Learning Health System. J Am Med Inform Assoc. 2014 Jul-Aug;21(4):602-6.

Forrest, CB, Margolis, PA, Seid, M, Colletti, RB. PEDSnet: how a prototype pediatric learning health system is being expanded into a national network. Health Aff (Millwood). 2014 Jul;33(7):1171-7.

Seid M, Margolis PA, Opipari-Arrigan L. Collaborative Chronic Care Networks (C3Ns) to transform chronic illness care. Pediatrics. 2013 Jun;131 Suppl 4:S219-23.

Fore D, Goldenhar LM, Margolis PA. Using goal-directed design to create a novel system for improving chronic illness care. JMIR Res Protoc. 2013 Oct 29;2(2):e43.

Kaplan HC, Adler J, Saeed SA, Eslick I, Margolis PA. A Personalized Learning System for Improving Patient-Physician Collaboration. Harvard Business Review, HBR Blog Network. 2013 Oct.

Kaplan HC, Froehle CM, Cassedy A, Provost LP, Margolis PA. An exploratory analysis of the model for understanding success in Quality. Health Care Manage Rev. 2013 Oct-Dec;38(4):325-38.

Margolis, PA, Peterson LE, Seid M. Collaborative Chronic Care Networks (C3Ns) to Transform Chronic Illness Care. Pediatrics. 2013 Jun;131:(4):eS219-23.

Zuckerman B, Margolis PA, Mate KS. Heath Services Innovation: the time is now. JAMA. 2013 Mar 20;309(11):1113-4.

Crandall WV, Margolis PA, Kappelman MD, King EC, Pratt JM, Boyle BM, Duffy LF, Grunow JE, Kim SC, Leibowitz I, Schoen BT, Colletti RB; for the ImproveCareNow Collaborative. Improved Outcomes in a Quality Improvement Collaborative for Pediatric Inflammatory Bowel Disease. Pediatrics. 2012 Apr;129(4):e1030-41.