A photo of Michael Seid.

Michael Seid, PhD

  • Director, Health Outcomes and Quality Care Research, Division of Pulmonary Medicine
  • Member, James M. Anderson Center for Health Systems Excellence
  • Professor, UC Department of Pediatrics



I use applied behavioral and social sciences to answer the question “What does it take for the healthcare system to work well for children with chronic health conditions?"

I view the healthcare system as a human system. The major goal of my research is to design, test and implement ways to enhance collaboration among all types of people (patients and families, clinicians, researchers and others) throughout the healthcare system. My colleagues and I have done this by increasing the number of people with the will and ability to self-organize, making it easier for them to create and share resources, and assisting them in forming teams to work on shared goals.

In our lab, we have created and replicated collaborative learning health systems or Learning Networks. These networks have improved outcomes for pediatric patients with a range of different medical conditions.

A major challenge is that there are more than 7,000 rare diseases and fewer than 20 Learning Networks. My research aims to make launching and growing Learning Networks easier and more effective so that everyone can be part of improving the healthcare system as a whole.

Other research interests stem from applied research in medical settings and human systems. I feel very satisfied to apply my interests in human systems, research training, and experience in applied research in healthcare settings to solve problems that matter. All of the discoveries that I participated in have been collaborative endeavors.

I’ve worked with other faculty at the Cincinnati Children’s Hospital Medical Center along with pediatric patients and parents to reconceptualize and redesign a prototype Collaborative Chronic Care Network. We have replicated this model in various Learning Networks and have created a computational model of Learning Networks to inform the search for mechanisms of action and best strategies for scaling Learning Networks.

I have more than 20 years’ experience in my field and first joined the Cincinnati Children’s Hospital Medical Center in 2006. I received the Cincinnati Children’s Team Science Award for Learning Networks, served as a member of the Health Care Quality and Effectiveness Research (HCQER) Study Section at the Agency for Healthcare Quality and Research, and on the Review Board of the Journal of Clinical Outcomes Management.

My research has been published in journals such as Statistics in Medicine, Learning Health Systems and Pediatric Quality and Safety.

PhD: Psychology, University of Illinois, Urbana-Champaign, 1995.

Services and Specialties

Cystic Fibrosis Center


Health care quality and outcomes

Research Areas

Pulmonary Medicine


Building a regional pediatric asthma learning health system in support of optimal, equitable outcomes. Beck, AF; Seid, M; McDowell, KM; Udoko, M; Cronin, SC; Makrozahopoulos, D; Powers, T; Fairbanks, S; Prideaux, J; Vaughn, LM; Hente, E; Thurmond, S; Unaka, NI. Learning Health Systems. 2024; 8:e10403.

Pre-exercise protein intake is associated with reduced time in hypoglycaemia among adolescents with type 1 diabetes. Muntis, FR; Crandell, JL; Evenson, KR; Maahs, DM; Seid, M; Shaikh, SR; Smith-Ryan, AE; Mayer-Davis, E. Diabetes, Obesity and Metabolism: a journal of pharmacology and therapeutics. 2024; 26:1366-1375.

Eating behaviors and estimated body fat percentage among adolescents with type 1 diabetes. Tran, T; Igudesman, D; Burger, K; Crandell, J; Maahs, DM; Seid, M; Mayer-Davis, EJ. Diabetes Research and Clinical Practice. 2024; 207:111070.

Conceptualizing and redefining successful patient engagement in patient advisory councils in learning health networks. Huwe, M; Woolf, B; David, J; Seid, M; Saeed, S; Margolis, P. Learning Health Systems. 2024; 8:e10377.

Establishing a Cystic Fibrosis Learning Network: Interventions to promote collaboration and data-driven improvement at scale. Ong, T; Albon, D; Amin, RS; Bailey, J; Bandla, S; Britto, MT; Flath, J; Gamel, B; Powers, M; Sabadosa, KA; Saulitis, AK; Thomas, LK; Thurmond, S; Seid, M. Learning Health Systems. 2023; 7:e10354.

The Cystic Fibrosis Learning Network: A mixed methods evaluation of program goals, attributes, and impact. Van Citters, AD; Buus-Frank, ME; King, JR; Seid, M; Holthoff, MM; Amin, RS; Britto, MT; Nelson, EC; Marshall, BC; Sabadosa, KA. Learning Health Systems. 2023; 7:e10356.

Comparative Effectiveness of Anti-TNF in Combination With Low-Dose Methotrexate vs Anti-TNF Monotherapy in Pediatric Crohn's Disease: A Pragmatic Randomized Trial. Kappelman, MD; Wohl, DA; Herfarth, HH; Firestine, AM; Adler, J; Ammoury, RF; Aronow, JE; Bass, DM; Bass, JA; Benkov, K; Zikry, M; Weinberger, M; Saeed, SA; Bousvaros, A. Gastroenterology. 2023; 165:149-161.e7.

A High Protein Diet Is Associated with Improved Glycemic Control Following Exercise among Adolescents with Type 1 Diabetes. Muntis, FR; Smith-Ryan, AE; Crandell, J; Evenson, KR; Maahs, DM; Seid, M; Shaikh, SR; Mayer-Davis, EJ. Nutrients. 2023; 15:1981.

More hypoglycemia not associated with increasing estimated adiposity in youth with type 1 diabetes. Sarteau, AC; Kahkoska, AR; Crandell, J; Igudesman, D; Corbin, KD; Kichler, JC; Maahs, DM; Muntis, F; Pratley, R; Seid, M; Zaharieva, D; Mayer-Davis, E. Pediatric Research. 2023; 93:708-714.

Web-Based Mindfulness-Based Interventions for Well-being: Randomized Comparative Effectiveness Trial. Sylvia, LG; Lunn, MR; Obedin-Maliver, J; McBurney, RN; Nowell, WB; Nosheny, RL; Mularski, RA; Long, MD; Merkel, PA; Pletcher, MJ; McCall, D; Terry, SF; Deckersbach, T; Nierenberg, AA. Journal of Medical Internet Research. 2022; 24:e35620.

From the Blog