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Stephanie L. Merhar, MD, MS


  • Attending Neonatologist, Perinatal Institute, Neonatology and Pulmonary Biology
  • Research Director, NICU Follow Up Clinic
  • Principal Investigator, Cincinnati site, NICHD Neonatal Research Network
  • Professor, UC Department of Pediatrics
In my practice, I listen carefully to families. I know that I don't have all of the answers and that parents know their child best.
Stephanie L. Merhar, MD, MS

About

Biography

Since I was 12 years old, I knew that I wanted to be a pediatrician. What could be better than being a doctor who gets to work with kids? During my pediatric residency at Cincinnati Children’s, I was drawn to neonatology because it offered me the opportunity to care for acutely ill babies and build long-term relationships with families through the neonatal intensive care unit (NICU) follow-up clinic.

As a neonatologist who cares for sick and preterm babies, I have a special interest in babies with brain injury and those exposed to substances such as opioids.

In my practice, I listen carefully to families. I know that I don't have all of the answers and that parents know their child best. In the NICU and our follow-up clinic, we collaborate with families and other care providers, such as neurologists, pulmonologists, therapists, nutritionists and nurses.

The research I do focuses on how the newborn brain can bounce back from insults including brain injury and substance exposure. I am also interested in using MRI as a tool to predict and improve the outcomes of term and preterm babies with brain injury. I am honored every time someone is interested in the research my team is doing.

MD: University of Pennsylvania, Philadelphia, PA, 2005

Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2008

Fellowship: Neonatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2011

Certifications: Pediatrics, 2008; Neonatal / Perinatal Medicine, 2011

Interests

Infants with perinatal brain injury; neonatal follow up.

Interests

Follow-up outcomes; advanced neuroimaging to predict outcomes in infants with brain injury and prenatal substance exposure

Additional Languages

French

Insurance Information

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Publications

Symptom-Based Dosing for Neonatal Opioid Withdrawal: The OPTimize NOW Randomized Clinical Trial. Devlin, LA; Babineau, DC; Merhar, SL; Demauro, SB; Kraft, WK; Lorch, SA; Das, A; Mcdonald, SA; Rhodes, E; Schmidt, AF; Anderson-Berry, A; Davis, JM; Poindexter, B; Young, LW. Journal of the American Medical Association (JAMA). 2026; 335(24):2114-2125.

Prenatal Substance Exposure and Birth Weight: Findings From the HEALthy Brain and Child Development Study. Bandoli, G; Psaras, C; Bakhireva, LN; Burris, HH; Ciciolla, L; Coles, CD; Demauro, SB; Osmundson, SS; Merhar, SL; Smith, L; Zink, J; Smyser, CD; Nelson, CA; Chambers, CD. Pediatrics. 2026; 157(6).

Antenatal Opioid Exposure and Cerebral Cortical Maturation in Newborns. Wu, Y; Merhar, SL; Bann, CM; Newman, JE; Kapse, K; De Asis-Cruz, J; Davis, JM; Ambalavanan, N; De Mauro, SB; Lorch, SA; Wilson-Costello, D; Poindexter, BB; Mack, N; Peralta-Carcelen, M; Limperopoulos, C. JAMA Network Open. 2026; 9(5):e2614115.

Temporal trends in outcomes for infants with neonatal opioid withdrawal managed with the Finnegan scoring tool: Insights from the INFORM NOW Study. Devlin, LA; Kraft, WK; Babineau, DC; Rhodes, E; Das, A; Crawford, M; Merhar, S; Telang, S; Leeman, L; Sokol, GM; Ambalavanan, N; Demauro, SB; Hall, RW; Lorch, SA. Journal of Perinatology. 2026.

Association between medication for opioid use disorder during pregnancy and neonatal outcomes. Hall, RW; Babineau, DC; Bangdiwala, AS; Rhodes, E; Venable, T; Asher, CC; Ambalavanan, N; Davis, JM; Adeniyi-Jones, S; Leeman, L; Merhar, S; Sokol, GM; Lorch, SA; Devlin, LA. Journal of Perinatology. 2026; 46(4):542-549.

Disrupted Brain Connectivity in Newborns Following Antenatal Opioid Exposure. De Asis-Cruz, J; Kim, J-H; Kapse, K; Wu, Y; Merhar, SL; Bann, CM; Newman, JE; Mack, N; Demauro, SB; Ambalavanan, N; Poindexter, BB; Peralta-Carcelen, M; Davis, JM; Limperopoulos, C. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 2026; 11(3):265-278.

Racial and ethnic disparities in environmental chemical exposures and hypertensive disorders of pregnancy: The ECHO-wide cohort study. Liu, H; Kress, AM; Yu, EX; Ning, X; Ghassabian, A; Kahn, LG; Mehta-Lee, S; Brubaker, S; Alshawabkeh, A; Meeker, J; Norman, G; Carignan, C; Zhao, Q; Trasande, L. Environmental Pollution. 2026; 392:127452.

Diffuse white matter abnormality is independently predictive of neurodevelopmental outcomes in preterm infants. Derbie, AY; Tamm, L; Kline-Fath, B; Li, H; Harpster, K; Merhar, SL; He, L; Altaye, M; Parikh, NA. Archives of Disease in Childhood: Fetal and Neonatal Edition. 2026; 111(2):F115-F122.

Expectant Management vs Medication for Patent Ductus Arteriosus in Preterm Infants: The PDA Randomized Clinical Trial. Laughon, MM; Thomas, SM; Watterberg, KL; Kennedy, KA; Keszler, M; Ambalavanan, N; Davis, AS; Slaughter, JL; Guillet, R; Colaizy, TT; Do, B; Chang, S; Higgins, RD; Walsh, MC. Journal of the American Medical Association (JAMA). 2026; 335(7):588-599.

Maternal Area of Residence and Outcomes for Mother-Infant Dyads with Perinatal Opioid Exposure. Pahl, A; Hu, Z; Young, LW; Ramsey, KW; Whalen, BL; Akshatha, A; Benninger, KL; Fung, CM; Howell, MP; Markee, S; Ounpraseuth, ST; Merhar, SL; Devlin, LA; Macmillan, KDL. American Journal of Perinatology. 2026; 43(3):383-395.

From the Blog

Newborn Brains Are Smaller When Exposed to Opioids During Gestation
Perinatal

Newborn Brains Are Smaller When Exposed to Opioids During Gestation

Stephanie L. Merhar, MD, MS4/10/2025

In Utero Opioid Exposure Impacts Fetal Brain Size and Development
Imaging Sciences

In Utero Opioid Exposure Impacts Fetal Brain Size and Development

Stephanie L. Merhar, MD, MS, Usha D. Nagaraj, MD9/28/2022

$8M Grant Funds Long-Term Opioid Exposure Study
Perinatal

$8M Grant Funds Long-Term Opioid Exposure Study

Stephanie L. Merhar, MD, MS10/6/2021

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