Omar Niss

Omar Niss, MD


  • Member, Division of Hematology
  • Director, Classical Hematology
  • Associate Professor, UC Department of Pediatrics

About

MD: Jordan University of Science and Technology, 2004.

Residency: Pediatrics, University of Nebraska Medical Center, Omaha, NE, 2010.

Fellowship: Pediatric Hematology Oncology, Cincinnati Children’s Hospital Medical Center, 2013; Sickle Cell Scholar, Cincinnati Children’s Hospital Medical Center, 2014.

Certification: Pediatrics, 2010; Pediatric Hematology/Oncology, 2015.

Interests

Pediatric hematology; sickle cell disease; hemoglobinopathies; congenital anemias; immune mediated cytopenia

Interests

Cardiopulmonary complications of sickle cell disease; congenital anemias

Research Areas

Additional Languages

Arabic, French

Insurance Information

Cincinnati Children's strives to accept a wide variety of health plans. Please contact your health insurance carrier to verify coverage for your specific benefit plan.

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Publications

Longitudinal changes and predictors of cardiac extracellular volume fraction in sickle cell anemia. Niss, O; Morin, CE; Hashemi, S; Alsaied, T; Lang, SM; Taylor, MD; Tasset, M; Malik, P; Quinn, CT. 2025; 1:100031.

A New First-Line Option for Pediatric ITP-Incremental Progress or Paradigm Shift?. Niss, O; Ware, RE; Quinn, CT. Journal of the American Medical Association (JAMA). 2025; 334:1802-1803.

Community Health Worker and Mobile Health Interventions for Quality of Life Among Young Adults With Sickle Cell Disease: A Randomized Clinical Trial. Jan, S; Steinway, C; Belton, T; Shults, J; Bennett, L; Teng, O; Griffis, H; Aygun, B; Appiah-Kubi, A; Apollonsky, N; Andemariam, B; Mulchan, SS; Rubin, D; Smith-Whitley, K. JAMA Network Open. 2025; 8:e2543571.

The Community Health Workers and Mobile Health for Emerging Adults Transitioning Sickle Cell Disease Care (COMETS) Trial: Protocol for a Randomized Controlled Trial. Belton, TD; Steinway, CM; Teng, O; Shults, J; Barakat, LP; Aygun, B; Appiah-Kubi, A; Crosby, LE; Niss, O; Andemariam, B; Johnson, TB; Rubin, DM; Smith-Whitley, KM; Jan, S. JMIR Research Protocols. 2025; 14:e69239.

Lentiviral gene therapy with reduced-intensity conditioning for sickle cell disease: a phase 1/2 trial. Grimley, M; Davies, SM; Shrestha, A; Shova, A; Asnani, M; Kent, M; Sayani, F; Quinn, CT; Niss, O; Lutzko, C; Witting, S; Latham, T; Bushman, FD; Malik, P. Nature Medicine. 2025; 31:2204-2212.

Gene Therapy with Reduced-Intensity Conditioning for Sickle Cell Disease. Davies, SM; Grimley, MS; Shrestha, A; Shova, A; Asnani, M; Kent, M; Sayani, F; Quinn, CT; Niss, O; Lutzko, CM; Witting, S; Latham, T; Bushman, FD; Malik, P. Transplantation and Cellular Therapy. 2025; 31:s2-s3.

Genetic variants in canonical Wnt signaling pathway associated with pediatric immune thrombocytopenia. Kim, TO; Geris, JM; Flanagan, JM; Grace, RF; Lambert, MP; O’Farrell, C; Rose, MJ; Shimano, KA; Niss, O; Neunert, C; Neufeld, EJ; Despotovic, JM; Scheurer, ME; Grimes, AB. Blood Advances. 2024; 8:5529-5538.

Community Health Worker and Mobile Health Programs to Help Young Adults with Sickle Cell Disease Transition to Using Adult Healthcare Services – the Comets Study; Results from Patient-Reported Outcomes at 6 Months. Jan, S; Steinway, C; Belton, T; Shults, J; Bennett, L; Griffis, H; Aygun, B; Appiah-Kubi, A; Apollonsky, N; Boruchov, D; Barakat, L; Andemariam, B; Rubin, D; Smith-Whitley, K. Blood. 2024; 144:1066.

Underutilization of Disease-Modifying Therapies in Sickle Cell Disease: A Real-World Analysis from the ASH Research Collaborative Data Hub. Niss, O; Fenchel, M; Kingsley, E; Latham, TS; Malik, P; Quinn, CT. Blood. 2024; 144:2312.

Community Health Worker Engagement with Adolescents and Young Adults with Sickle Cell Disease: Findings from the Comets Study. Forrest, J; Steinway, C; Shaw, E; Jan, S; Aygun, B; Appiah-Kubi, A; Apollonsky, N; Boruchov, D; Niss, O; Andemariam, B; Smith-Whitley, K; Trachtenberg, S; Belton, T. Blood. 2024; 144:617.

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