Punam Malik, MD
- Director, Cincinnati Comprehensive Sickle Cell Center
- Program Leader, Hematology and Gene Therapy Program
- Marjory J. Johnson Chair, Gene and Cell Therapy
- Professor, UC Department of Pediatrics
- punam.malik@cchmc.org
- Board Certified
About
MBBS: University of Delhi, New Delhi, India, 1985.
MD: University of Delhi, New Delhi, India, 1989.
MS: University of Maryland, Baltimore, MD, 1991.
Fellowship: Children's Hospital Los Angeles, University of Southern California, 1995.
Services and Specialties
Research Areas
Insurance Information
Cincinnati Children's strives to accept a wide variety of health plans. Please contact your health insurance carrier to verify coverage for your specific benefit plan.
Publications
Underutilization of Disease-Modifying Therapies in Sickle Cell Disease: A Real-World Analysis from the ASH Research Collaborative Data Hub. Blood. 2024; 144:2312.
Blockade of Angiotensin II Signaling Ameliorates Cardiac Fibrosis and Improves Diastolic Dysfunction in Mice with Sickle Cell Anemia. Blood. 2024; 144:2480.
Splenic Ossification in Sickle Cell Anemia Mice. Blood. 2024; 144:5283.
A Novel Mouse Model of Hemoglobin-SC Disease: Bridging the Knowledge Gap in Sickle Cell Disease. Blood. 2024; 144:620.
Longitudinal Assessment of Myocardial Fibrosis in Sickle Cell Disease. Blood. 2024; 144:799.
Preclinical safety assessment of modified gamma globin lentiviral vector-mediated autologous hematopoietic stem cell gene therapy for hemoglobinopathies. PloS one. 2024; 19:e0306719.
NRASQ61R mutation drives elevated angiopoietin-2 expression in human endothelial cells and a genetic mouse model. Pediatric Blood and Cancer. 2024; 71:e31032.
CRISPR/Cas9 deletion of MIR155HG in human T cells reduces incidence and severity of acute GVHD in a xenogeneic model. Blood Advances. 2024; 8:947-958.
Generation of a tyrosine hydroxylase-2A-Cre knockin non-human primate model by homology-directed-repair-biased CRISPR genome editing. Cell Reports: Methods. 2023; 3:100590.
Strategies for precise gene edits in mammalian cells. Molecular Therapy-Nucleic Acids. 2023; 32:536-552.
From the Blog
Preventing Adult Sickle Cell Deaths From Kidney Disease May Start With Improved Childhood Testing
Punam Malik, MD, Omar Niss, MD4/15/2020
Gene Therapy Advances Raise Hopes for Curing Sickle Cell Disease
Punam Malik, MD6/27/2019
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