A photo of Nehal Parikh.

Attending Neonatologist, Perinatal Institute

Professor, UC Department of Pediatrics

513-636-7584

Board Certified

My Biography & Research

Biography

I specialize in neonatology and practice evidence-based healthcare and family-centered care. More specifically, my specialties include:

  • Bronchopulmonary dysplasia
  • Cerebral palsy
  • Cognitive impairments
  • Encephalopathy of prematurity
  • Neonatal hypoxic-ischemic encephalopathy
  • Retinopathy of prematurity

I work with the pediatric population because of an overwhelming desire to serve vulnerable communities and because of my love for children. Due to this, pediatrics was a natural and clear choice for me. Once I learned about the great need for research into the causes and outcomes of neurodevelopmental disorders in high-risk populations, I became interested in this research area. My desire is to help these babies and their families.

While neonatology has successfully improved the survival of sick-term and preterm neonates, this medical field has made far slower progress in enhancing quality of life. This is mainly due to the high risk of perinatal/neonatal brain injury in (NICU) patients.

In my research, there are two main goals my colleagues and I are trying to accomplish. First, we are attempting to predict and diagnose neurodevelopmental conditions early in high-risk neonates. Our second goal is to foster and implement early treatment to prevent high-risk neonates from developing neurodevelopmental conditions.

My focus as a clinician-scientist is on early diagnosis, prognosis and prevention of neurodevelopmental impairments. My colleagues and I are conducting longitudinal cohort studies of advanced magnetic resonance imaging (MRI) and neurodevelopmental results. We are looking at accelerating early detection of neurodevelopmental conditions and randomized trials of neuroprotective interventions.

In 2002, I received the Thomas Boggs Jr. Young Investigator Award during the last year of my neonatology fellowship. The Philadelphia Perinatal Society awards this honor annually to one of the top fellows from the Philadelphia neonatal-perinatal programs who has conducted the most exceptional research during their training. In 2013, I also received the Distinguished Educator Award from the neonatology fellows at Nationwide Children's Hospital, which was given to me for my commitment to teaching the fellows evidence-based medicine.

I have more than 15 years’ experience in this field and my research has received National Institutes of Health (NIH) and institutional funding since 2005. I have also used two R01 grants from the National Institutes of Health and the National Institute of Neurological Disorders and Stroke to fund the use of advanced MRI modalities, such as diffusion and functional MRI. This study explores the causes and long-term outcomes of premature infants' encephalopathy with the near-term goal of early detection of neurodevelopmental conditions.

Clinical Interests

Evidence-based and family-centered care of very premature infants and term infants with asphyxia/neonatal encephalopathy; critically-ill newborns

Research Interests

Early diagnosis of perinatal brain injury/delayed brain development; early detection and prevention of neurodevelopmental disabilities

Academic Affiliation

Professor, UC Department of Pediatrics

Clinical Divisions

Perinatal, Neonatology, Newborn Intensive Care NICU

Research Divisions

Neonatology, Imaging



Blog Posts

My Education

DO: NY College of Osteopathic Medicine of NY Institute of Technology, Long Island, NY, 1996.

Residency: Pediatrics, Winthrop University Hospital of SUNY Stony Brook, Long Island, NY, 1999.

Fellowship: Neonatology, Thomas Jefferson University of Jefferson Medical College, Philadelphia, PA, 2002.

MS: Translational/Clinical Research, University of Texas Medical School at Houston, Houston, TX, 2007.

Certification: Pediatrics, 1996.

Certification: Neonatology, 2003.

My Publications

A multi-task, multi-stage deep transfer learning model for early prediction of neurodevelopment in very preterm infants. He, L; Li, H; Wang, J; Chen, M; Gozdas, E; Dillman, JR; Parikh, NA. Scientific Reports. 2020; 10.

Novel diffuse white matter abnormality biomarker at term-equivalent age enhances prediction of long-term motor development in very preterm children. Parikh, NA; Harpster, K; He, L; Illapani, VS P; Khalid, FC; Klebanoff, MA; O’Shea, TM; Altaye, M. Scientific Reports. 2020; 10.

Extremely Preterm Children Demonstrate Interhemispheric Hyperconnectivity During Verb Generation: a Multimodal Approach. Barnes-Davis, ME; Merhar, SL; Holland, SK; Parikh, NA; Kadis, DS. 2020.

Early Prediction of Cognitive Deficit in Very Preterm Infants Using Brain Structural Connectome With Transfer Learning Enhanced Deep Convolutional Neural Networks. Chen, M; Li, H; Wang, J; Yuan, W; Altaye, M; Parikh, NA; He, L. Frontiers in Neuroscience. 2020; 14.

Early cortical maturation predicts neurodevelopment in very preterm infants. Kline, JE; Illapani, VS P; He, L; Altaye, M; Logan, JW; Parikh, NA. Archives of Disease in Childhood: Fetal and Neonatal Edition. 2020; 105:460-465.

Objectively Diagnosed Diffuse White Matter Abnormality at Term Is an Independent Predictor of Cognitive and Language Outcomes in Infants Born Very Preterm. Parikh, NA; He, L; Illapani, VS P; Altaye, M; Folger, AT; Yeates, KO. The Journal of Pediatrics. 2020; 220:56-63.

Early brain abnormalities in infants born very preterm predict under-reactive temperament. Tamm, L; Patel, M; Peugh, J; Kline-Fath, BM; Parikh, NA; Cincinnati, IN E P. Early Human Development. 2020; 144:104985-104985.

Antecedents of Objectively Diagnosed Diffuse White Matter Abnormality in Very Preterm Infants. Parikh, NA; He, L; Li, H; Illapani, VS P; Klebanoff, MA. Pediatric Neurology. 2020; 106:56-62.

Behavior Profiles at 2 Years for Children Born Extremely Preterm with Bronchopulmonary Dysplasia. Brumbaugh, JE; Bell, EF; Grey, SF; DeMauro, SB; Vohr, BR; Harmon, HM; Bann, CM; Rysavy, MA; Logan, JW; Colaizy, TT; et al. The Journal of Pediatrics. 2020; 219:152-159.e5.

Timing of postnatal steroids for bronchopulmonary dysplasia: association with pulmonary and neurodevelopmental outcomes. Harmon, HM; Jensen, EA; Tan, S; Chaudhary, AS; Slaughter, JL; Bell, EF; Wyckoff, MH; Hensman, AM; Sokol, GM; DeMauro, SB; et al. Journal of Perinatology. 2020; 40:616-627.