About

Biography

My interest in pediatric medicine began with the idea that diseases can be prevented and managed in childhood to avoid complications as adults. My career and research now focus on the complications of obesity in children and adolescents. Type 2 diabetes, cholesterol issues and blood pressure problems, once thought to be adult diseases, are also seen more and more often in young people with obesity.

Currently, my research focuses on obesity and Type 2 diabetes and their long-term health consequences. With my work, I try to determine how the complications of diabetes, including cardiovascular disease, start, and how diabetes increases the risk for cardiovascular disease. I hope to understand how to prevent Type 2 diabetes in adolescents and reduce health problems in the future.

I serve as the director of the Adolescent Type 2 Diabetes Program at Cincinnati Children’s Hospital Medical Center. In this setting, my colleagues and I work as a team to discover the best medical treatments for youth with Type 2 diabetes. We have a comprehensive clinical team that includes gastroenterologists to assess for fatty liver disease, psychologists, nutritionists, certified diabetes educators and social workers. We also work with the bariatric surgery team to understand how bariatric surgery effects youth-onset Type 2 diabetes and its complications.

I have received several awards and honors, including:

  • 2014 Young Investigator Award, The International Society of Pediatric and Adolescent Diabetes
  • 2015 and 2016 Young Investigator Award, The National Lipid Association
  • 2016 Young Physician Scientist Award, The American Society of Clinical Investigation
  • 2016 Early Career Development Award, The Central Society for Clinical and Translational Research
  • 2020 Nominated as a Fellow of the National Lipid Association

Locations (2)

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Publications

Relationship between Arterial Stiffness and Subsequent Cardiac Structure and Function in Young Adults with Youth-Onset Type 2 Diabetes: Results from the TODAY Study. Shah, AS; Gidding, SS; El ghormli, L; Tryggestad, JB; Nadeau, KJ; Bacha, F; Levitt Katz, LE; Willi, SM; Lima, J; Urbina, EM. Journal of the American Society of Echocardiography. 2022.

Rare Presentation of Pediatric Multiple Enchondromatosis Limited to Single Ray or Single Nerve Distribution in the Hand: A Multicenter Case Series. Muffly, BT; O'Shaughnessy, MA; Fazal, FZ; Riley, SA; Shah, AS; Cornwall, R; Burke, CS. Journal of Pediatric Orthopaedics. 2022.

Type 2 diabetes in youth: Rationale for use of off-label antidiabetic agents. Kelsey, MM; Zeitler, PS; Nadeau, KJ; Shah, AS. Pediatric Diabetes. 2022.

Greasing the inflammatory pathogenesis of viral pneumonias in diabetes. Damen, MS M A; Alarcon, PC; Shah, AS; Divanovic, S. Obesity Reviews. 2022; 23.

Cerebral blood flow is lower in youth with type 2 diabetes compared to obese controls: A pilot study. Redel, JM; DiFrancesco, M; Lee, GR; Ziv, A; Dolan, LM; Brady, CC; Shah, AS. Pediatric Diabetes. 2022; 23:291-300.

Conformational flexibility of apolipoprotein A-I amino- and carboxy-termini is necessary for lipid binding but not cholesterol efflux. Bedi, S; Morris, J; Shah, A; Hart, RC; Gray Jerome, W; Aller, SG; Tang, C; Vaisar, T; Bornfeldt, KE; Segrest, JP; et al. Journal of Lipid Research. 2022; 63.

Longitudinal changes in vascular stiffness and heart rate variability among young adults with youth-onset type 2 diabetes: results from the follow-up observational treatment options for type 2 diabetes in adolescents and youth (TODAY) study. Shah, AS; El ghormli, L; Gidding, SS; Hughan, KS; Levitt Katz, LE; Koren, D; Tryggestad, JB; Bacha, F; Braffett, BH; Arslanian, S; et al. Acta Diabetologica. 2022; 59:197-205.

The HDL Proteome Watch: Compilation of studies leads to new insights on HDL function. Davidson, WS; Shah, AS; Sexmith, H; Gordon, SM. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 2022; 1867.

Trends in Glycemic Control Among Youth and Young Adults With Diabetes: The SEARCH for Diabetes in Youth Study. Malik, FS; Sauder, KA; Isom, S; Reboussin, BA; Dabelea, D; Lawrence, JM; Roberts, A; Mayer-Davis, EJ; Marcovina, S; Dolan, L; et al. Diabetes Care. 2022; 45:285-294.

Lipids: a Potential Molecular Pathway Towards Diastolic Dysfunction in Youth-Onset Type 2 Diabetes. Shah, AS; Sadayappan, S; Urbina, EM. Current Atherosclerosis Reports. 2022; 24:109-117.

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