A photo of Amy Shah.

Amy S. Shah, MD, MS, FNLA

  • Director, Adolescent Type 2 Diabetes Program
  • Director, Research Operations, Endocrinology
  • Associate Program Director, BMCP T32 Training Grant
  • Professor, UC Department of Pediatrics



My interest in pediatric medicine began with the idea that diseases can be prevented and managed in childhood to avoid complications as adults. My career and research now focus on the complications of chronic diseases that begin in childhood. Type 2 diabetes, cholesterol issues and blood pressure problems, once thought to be adult diseases, are also seen more and more often in young people.

Currently, my research focuses on prevention of diabetes and if diabetes develops, its long-term health consequences. With my work, I try to determine how diabetes may impact the heart, brain and blood vessels. I hope to understand how to prevent diabetes in adolescents and reduce health problems in the future.

I serve as the director of the Adolescent Type 2 Diabetes Program at Cincinnati Children’s Hospital Medical Center. In this setting, my colleagues and I work as a team to discover the best medical and surgical treatments for youth with Type 2 diabetes. We have a comprehensive clinical team that includes gastroenterologists to assess for fatty liver disease, psychologists, nutritionists, certified diabetes educators and social workers. We also work with the bariatric surgery team to understand how bariatric surgery effects youth-onset Type 2 diabetes and its complications.

I have received several awards and honors, including:

  • 2014 Young Investigator Award, The International Society of Pediatric and Adolescent Diabetes
  • 2015 and 2016 Young Investigator Award, The National Lipid Association
  • 2016 Young Physician Scientist Award, The American Society of Clinical Investigation
  • 2016 Early Career Development Award, The Central Society for Clinical and Translational Research
  • 2020 Nominated as a Fellow of the National Lipid Association

BA: Biology, The University of Texas at Austin, Austin, TX, 2000. 

MD: St. George’s University Medical School, Grenada, West Indies, 2004.

Pediatric Residency: Loyola University Medical Center, Maywood, IL, 2007.

Endocrine Fellowship: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2010.

Research Fellowship: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2011.

MS: Clinical Research, The University of Cincinnati, Cincinnati, OH, 2011.

Certifications: The American Board of Pediatrics, Subspeciality Board in Pediatric Endocrinology, Clinical Lipidology.


Type 2 diabetes; obesity; primary and secondary lipid disorders; hypertension; general endocrinology

Services and Specialties



Type 2 diabetes; type 1 diabetes; cardiovascular risk factors; lipids and lipoproteins

Research Areas


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Presurgery health influences outcomes following vertical sleeve gastrectomy in adolescents. Swertfeger, D; Kim, A; Sexmith, H; Moreno-Fernandez, ME; Davidson, WS; Helmrath, M; Jenkins, T; Okura, T; Geh, E; Xanthakos, SA; Szabo, S; Nakamura, T; Divanovic, S; Shah, AS. Obesity. 2024; 32:1187-1197.

Abstract MP60: A Randomized Placebo-Controlled Trial of Pitavastatin Calcium to Treat Combined Dyslipidemia of Obesity in Adolescents - The Pediatric Heart Network Dyslipidemia of Obesity Intervention in Teens (Do It!) Trial. McCrindle, BW; Arslanian, S; Mietus-Snyder, M; Urbina, EM; Ware, A; Teng, JE; Trachtenberg, F; Russell, M; Shah, AS; Cartoski, M; Kazlova, V; Sponseller, CA; Freemon, D; Deferranti, S. Circulation. 2024; 149:amp60.

A novel assay to measure low-density lipoproteins binding to proteoglycans. Geh, EN; Swertfeger, DK; Sexmith, H; Heink, A; Tarapore, P; Melchior, JT; Davidson, WS; Shah, AS. PloS one. 2024; 19:e0291632.

High Rate of Islets Autoimmunity in Pediatric Patients with Index Admission of Acute Pancreatitis. Tatum, JD; Hornung, L; Bellin, MD; Elder, DA; Thompson, T; Vitale, DS; Wasserfall, CH; Shah, AS; Abu-El-Haija, M. Pediatric Diabetes. 2023; 2023:1-9.

Weekly insulin: a paradigm shift in type 1 diabetes therapy. Shah, AS; Wolf, RM. The Lancet. 2023; 402:1598-1599.

Prevalence of islet cell autoimmunity in paediatric patients in index cases of acute pancreatitis. Tatum, J; Hornung, L; Vitale, D; Bellin, M; Wasserfall, C; Thompson, T; Shah, A; Abu-El-Haija, M. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 2023; 23:e34.

Household Food Insecurity and Cognition in Youth and Young Adults with Youth-Onset Diabetes. Brown, AD; Liese, AD; Shapiro, AL B; Frongillo, EA; Wilkening, G; Fridriksson, J; Merchant, AT; Henkin, L; Jensen, ET; Reboussin, BA; Dolan, LM; Dabelea, D; Pihoker, C; Mendoza, JA. Pediatric Diabetes. 2023; 2023:6382663.

Development and Implementation of a Multidisciplinary Clinic Focused on the Care of Adolescents with Youth-Onset Type 2 Diabetes. Schaaf, L; Ley, S; Riegler, A; Poetker, A; Xanthakos, S; Sizemore, J; Crimmins, N; Helmrath, M; Tracy, R; Arce-Clachar, AC; Crail, J; Morwessel, N; Frenck, K; Tariq, F; Shah, AS. Journal of Multidisciplinary Healthcare. 2023; 16:2799-2807.

221-OR: Retrospective Review of Genetic Mutations and Treatments in Patients with Monogenic Diabetes of the Youth (MODY). DENG, L; SHAH, AS; KRISHNAMURTHY, M. Diabetes. 2023; 72.

1115-P: Advanced Medical Therapy (AMT) for Youth-Onset Type 2 Diabetes (T2D)—Early Results from the Run-in Phase of ST2OMP. SHAH, AS; KELSEY, MM; JENKINS, TM; SCHAAF, LR; XANTHAKOS, S; TROUT, AT; BAUMGARTNER, AM Y; RIEGLER, A; KRISHNAN, N; BAILEY, A; INGE, T; HELMRATH, M; NADEAU, KJ. Diabetes. 2023; 72.

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