A photo of Amy Shah.

Director, Adolescent Type 2 Diabetes Program

Associate Professor, UC Department of Pediatrics



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My Biography & Research


My interest in pediatric medicine began with the idea that diseases can be prevented and managed in childhood to avoid complications as adults. My career and research now focus on the complications of obesity in children and adolescents. Type 2 diabetes, cholesterol issues and blood pressure problems, once thought to be adult diseases, are also seen more and more often in young people with obesity.

Currently, my research focuses on obesity and Type 2 diabetes and their long-term health consequences. With my work, I try to determine how the complications of diabetes, including cardiovascular disease, start, and how diabetes increases the risk for cardiovascular disease. I hope to understand how to prevent Type 2 diabetes in adolescents and reduce health problems in the future.

I serve as the director of the Adolescent Type 2 Diabetes Program at Cincinnati Children’s Hospital Medical Center. In this setting, my colleagues and I work as a team to discover the best medical treatments for youth with Type 2 diabetes. We have a comprehensive clinical team that includes gastroenterologists to assess for fatty liver disease, psychologists, nutritionists, certified diabetes educators and social workers. We also work with the bariatric surgery team to understand how bariatric surgery effects youth-onset Type 2 diabetes and its complications.

I have received several awards and honors, including:

  • 2014 Young Investigator Award, The International Society of Pediatric and Adolescent Diabetes
  • 2015 and 2016 Young Investigator Award, The National Lipid Association
  • 2016 Young Physician Scientist Award, The American Society of Clinical Investigation
  • 2016 Early Career Development Award, The Central Society for Clinical and Translational Research
  • 2020 Nominated as a Fellow of the National Lipid Association

Clinical Interests

Type 2 diabetes; obesity; primary and secondary lipid disorders; hypertension; general endocrinology

Research Interests

Type 2 diabetes; type 1 diabetes; cardiovascular risk factors; lipids and lipoproteins

Academic Affiliation

Associate Professor, UC Department of Pediatrics

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My Locations

My Education

BA: Biology, The University of Texas at Austin, Austin, TX, 2000. 

MD: St. George’s University Medical School, Grenada, West Indies, 2004.

Pediatric Residency: Loyola University Medical Center, Maywood, IL, 2007.

Endocrine Fellowship: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2010.

Research Fellowship: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2011.

MS: Clinical Research, The University of Cincinnati, Cincinnati, OH, 2011.

Certifications: The American Board of Pediatrics, Subspeciality Board in Pediatric Endocrinology, Clinical Lipidology.

My Publications

Longitudinal changes in vascular stiffness and heart rate variability among young adults with youth-onset type 2 diabetes: results from the follow-up observational treatment options for type 2 diabetes in adolescents and youth (TODAY) study. Shah, AS; El ghormli, L; Gidding, SS; Hughan, KS; Levitt Katz, LE; Koren, D; Tryggestad, JB; Bacha, F; Braffett, BH; Arslanian, S; et al. Acta Diabetologica. 2021.

Study protocol: a prospective controlled clinical trial to assess surgical or medical treatment for paediatric type 2 diabetes (ST2OMP). Shah, AS; Helmrath, MA; Inge, TH; Xanthakos, SA; Kelsey, MM; Jenkins, T; Trout, AT; Browne, L; Nadeau, KJ. BMJ Open. 2021; 11.

Case Studies in Pediatric Lipid Disorders and Their Management. Ashraf, AP; Sunil, B; Bamba, V; Breidbart, E; Brar, PC; Chung, S; Gupta, A; Khokhar, A; Kumar, S; Lightbourne, M; et al. Journal of Clinical Endocrinology and Metabolism. 2021.

Associations of Genetically Predicted Lp(a) (Lipoprotein [a]) Levels With Cardiovascular Traits in Individuals of European and African Ancestry. Satterfield, BA; Dikilitas, O; Safarova, MS; Clarke, SL; Tcheandjieu, C; Zhu, X; Bastarache, L; Larson, EB; Justice, AE; Shang, N; et al. Circulation: Genomic and Precision Medicine. 2021; 14.

Apolipoprotein A-I modulates HDL particle size in the absence of apolipoprotein A-II. Melchior, JT; Street, SE; Vaisar, T; Hart, R; Jerome, J; Kuklenyik, Z; Clouet-Foraison, N; Thornock, C; Bedi, S; Shah, AS; et al. Journal of Lipid Research. 2021; 62.

Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes. Robertson, CC; Inshaw, JR J; Onengut-Gumuscu, S; Chen, WM; Santa Cruz, DF; Yang, H; Cutler, AJ; Crouch, DJ M; Farber, E; Bridges, SL; et al. Nature Genetics. 2021; 53:962-971.

Medical and surgical interventions and outcomes for infants with trisomy 18 (T18) or trisomy 13 (T13) at children's hospitals neonatal intensive care units (NICUs). Acharya, K; Leuthner, SR; Zaniletti, I; Niehaus, JZ; Bishop, CE; Coghill, CH; Datta, A; Dereddy, N; DiGeronimo, R; Jackson, L; et al. Journal of Perinatology. 2021; 41:1745-1754.

902-P: Screening for Gastric Motor Abnormalities in Pediatric Patients with Type 1 Diabetes: A Cross-Sectional Study. MASHALI, G; KAUL, AA; DOLAN, LM; KHOURY, JC; SHAH, AS. Diabetes. 2021; 70:902-p.

The Difference Between High Density Lipoprotein Subfractions and Subspecies: an Evolving Model in Cardiovascular Disease and Diabetes. Davidson, WS; Cooke, AL; Swertfeger, DK; Shah, AS. Current Atherosclerosis Reports. 2021; 23.

Cognitive Function in Adolescents and Young Adults With Youth-Onset Type 1 Versus Type 2 Diabetes: The SEARCH for Diabetes in Youth Study. Shapiro, AL B; Dabelea, D; Stafford, JM; D'Agostino, R; Pihoker, C; Liese, AD; Shah, AS; Bellatorre, A; Lawrence, JM; Henkin, L; et al. Diabetes Care. 2021; 44:1273-1280.