Elizabeth Smith

Elizabeth G. Smith, PhD


  • Clinical Psychologist, Division of Behavioral Medicine and Clinical Psychology
  • Assistant Professor, UC Department of Pediatrics

About

Bachelor of Science: Psychology, specialty in Neuroscience, Duke University,

Undergraduate Research Assistant: Duke University and the University of North Carolina at Chapel Hill; focused on infant development, autism, and neuroimaging.

PhD: Clinical Psychology, University of Rochester, under mentorship of Dr. Loisa Bennetto; studied the relation between sensory perception and language in autism.

Postdoctoral training: National Institutes of Health with Dr. Audrey Thurm; focused on neuroimaging, including both MRI and fNIRS, in young children with neurodevelopmental disorders.

Postdoctoral training: with Dr. Nathan Fox at the University of Maryland at College Park in multimodal neuroimaging with NIRS and EEG.

Interests

Very young children with fragile X syndrome; how symptoms related to sensory processing, language, cognition, and anxiety emerge over the first five years of life; differential diagnosis of symptoms seen in neurodevelopmental disorders, including those seen in autism, anxiety, mood disorders, ADHD, and other behavioral health concerns.

Interests

How brain development, a child's environment, and individual variability interact to drive phenotypic variability/outcomes for children with neurodevelopmental disorders; how hearing, auditory sensitivity, and neural responses to speech and nonspeech sounds are related to language development in infants and toddlers with fragile X syndrome.

Publications

Brain Morphometry of Toddlers With Language Delay: An Exploratory Study. Filippi, CA; Smith, E; Redcay, E; Hazlett, H; Thompson, L; Manwaring, SS; D'Souza, P; Thurm, A. Infant and Child Development. 2025; 34.

Specialization of the brain for language in children with Fragile X Syndrome: a functional Near Infrared Spectroscopy study. Smith, E; Dominick, KC; Schmitt, LM; Pedapati, EV; Erickson, CA. Journal of Neurodevelopmental Disorders. 2024; 16:69.

Reliability of resting-state electrophysiology in fragile X syndrome. Liu, R; Pedapati, EV; Schmitt, LM; Shaffer, RC; Smith, EG; Dominick, KC; DeStefano, LA; Westerkamp, G; Horn, P; Sweeney, JA; Erickson, CA. Biomarkers in Neuropsychiatry. 2023; 9:100070.

Results of a phase Ib study of SB-121, an investigational probiotic formulation, a randomized controlled trial in participants with autism spectrum disorder. Schmitt, LM; Smith, EG; Pedapati, EV; Horn, PS; Will, M; Lamy, M; Barber, L; Trebley, J; Meyer, K; Heiman, M; West, KH J; Hughes, P; Ahuja, S; Erickson, CA. Scientific Reports. 2023; 13:5192.

Posterior superior temporal cortex connectivity is related to social communication in toddlers. Smith, E; Xiao, Y; Xie, H; Manwaring, SS; Farmer, C; Thompson, L; D'Souza, P; Thurm, A; Redcay, E. Infant Behavior and Development. 2023; 71:101831.

Systematic Review: Emotion Dysregulation in Syndromic Causes of Intellectual and Developmental Disabilities. Shaffer, RC; Reisinger, DL; Schmitt, LM; Lamy, M; Dominick, KC; Smith, EG; Coffman, MC; Esbensen, AJ. Journal of the American Academy of Child and Adolescent Psychiatry. 2023; 62:518-557.

Neocortical localization and thalamocortical modulation of neuronal hyperexcitability contribute to Fragile X Syndrome. Pedapati, EV; Schmitt, LM; Ethridge, LE; Miyakoshi, M; Sweeney, JA; Liu, R; Smith, E; Shaffer, RC; Dominick, KC; Gilbert, DL; Binder, DK; Lamy, M; Axford, M; Erickson, CA. Communications Biology. 2022; 5:442.

Observable Symptoms of Anxiety in Individuals with Fragile X Syndrome: Parent and Caregiver Perspectives. Lozano, R; Thompson, T; Dixon-Weber, J; Erickson, CA; Berry-Kravis, E; Williams, S; Smith, E; Frazier, JA; Rosselot, H; Farmer, C; Hessl, D. Genes. 2022; 13:1660.

Infant temperament prospectively predicts general psychopathology in childhood. Morales, S; Tang, A; Bowers, ME; Miller, NV; Buzzell, GA; Smith, E; Seddio, K; Henderson, HA; Fox, NA. Development and Psychopathology. 2022; 34:774-783.

Structured sparse multiset canonical correlation analysis of simultaneous fNIRS and EEG provides new insights into the human action-observation network. Dashtestani, H; Miguel, HO; Condy, EE; Zeytinoglu, S; Millerhagen, JB; Debnath, R; Smith, E; Adali, T; Fox, NA; Gandjbakhche, AH. Scientific Reports. 2022; 12:6878.

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4.6
Overall Patient Rating