A photo of Keith Stringer.

Keith F. Stringer, MD


  • Pathologist, Division of Pathology and Laboratory Medicine
  • Associate Professor, UC Department of Pediatrics

About

Biography

With my colleagues, I aim to decipher mechanisms of disease using a variety of microscopy techniques. I try to determine what abnormalities are present, as well as when and where. I am particularly interested in cancer biology, inflammatory response and musculoskeletal aberrations.

My path to research was paved by a curiosity about mysterious, small-scale failures that lead to abnormal functioning in tissues. I love using a microscope, and I have always wanted to help the sick.

A challenge in many tissue studies is identifying which cells make which product. As a pediatric pathologist, I am pleased to contribute to several such co-localization studies involving lesions caused by immunological and cancerous cell changes.

I have won many awards for molecular pathology teaching, including multiple Gold Apple teaching awards from medical students, and multiple Clinical Pathology Teacher of the Year awards from residents. I have also received the Dean’s Award for Teaching Excellence from the College of Medicine.

Publications

Identification of alternative protein targets of glutamate-ureido-lysine associated with PSMA tracer uptake in prostate cancer cells. Bakht, MK; Hayward, JJ; Shahbazi-Raz, F; Skubal, M; Tamura, R; Stringer, KF; Meister, D; Venkadakrishnan, VB; Xue, H; Pillon, A; et al. Proceedings of the National Academy of Sciences of the United States of America. 2022; 119.

Integration of Genomic Medicine in Pathology Resident Training. Haspel, RL; Genzen, JR; Wagner, J; Lockwood, CM; Fong, K; Adesina, AM; Browning, L; Chabot-Richards, D; Cushman-Vokoun, AM; D’Angelo, AR; et al. American Journal of Clinical Pathology. 2020; 154:784-791.

Cyclin-like proteins tip regenerative balance in the liver to favour cancer formation. Fifield, B; Talia, J; Stoyanovich, C; Elliott, MJ; Bakht, MK; Basilious, A; Samsoondar, JP; Curtis, M; Stringer, KF; Porter, LA. Carcinogenesis. 2020; 41:850-862.

Differential Expression of Glucose Transporters and Hexokinases in Prostate Cancer with a Neuroendocrine Gene Signature: A Mechanistic Perspective for 18F-FDG Imaging of PSMA-Suppressed Tumors. Bakht, MK; Lovnicki, JM; Tubman, J; Stringer, KF; Chiaramonte, J; Reynolds, MR; Derecichei, I; Ferraiuolo, R; Fifield, B; Lubanska, D; et al. Journal of Nuclear Medicine. 2020; 61:904-910.

Juvenile OLFM4-null mice are protected from sepsis. Stark, JE; Opoka, AM; Mallela, J; Devarajan, P; Ma, Q; Levinsky, NC; Stringer, KF; Wong, HR; Alder, MN. American Journal of Physiology - Renal Physiology. 2020; 318:F809-F816.

Assessment of Enhanced Thermal Effect Due to Gold Nanoparticles during MR-Guided High-Intensity Focused Ultrasound (HIFU) Procedures Using a Mouse-Tumor Model. Devarakonda, SB; Stringer, K; Rao, M; Myers, M; Banerjee, R. ACS Biomaterials Science and Engineering. 2019; 5:4102-4111.

Neuroendocrine differentiation of prostate cancer leads to PSMA suppression. Bakht, MK; Derecichei, I; Li, Y; Ferraiuolo, R; Dunning, M; Oh, SW; Hussein, A; Youn, H; Stringer, KF; Jeong, CW; et al. Endocrine-Related Cancer. 2019; 26:131-146.

Sepsis Induces Adipose Tissue Browning in Nonobese Mice But Not in Obese Mice. Ayalon, I; Shen, H; Williamson, L; Stringer, K; Zingarelli, B; Kaplan, JM. Shock. 2018; 50:557-564.

Proximal Femoral Growth Modification: Effect of Screw, Plate, and Drill on Asymmetric Growth of the Hip. d'Heurle, A; McCarthy, J; Klimaski, D; Stringer, K. Journal of Pediatric Orthopaedics. 2018; 38:100-104.

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