Keith F. Stringer, MD

Pathologist, Division of Pathology and Laboratory Medicine
Associate Professor, UC Department of Pediatrics

keith.stringer@cchmc.org
Board Certified

About

Biography

With my colleagues, I aim to decipher mechanisms of disease using a variety of microscopy techniques. I try to determine what abnormalities are present, as well as when and where. I am particularly interested in cancer biology, inflammatory response and musculoskeletal aberrations.

My path to research was paved by a curiosity about mysterious, small-scale failures that lead to abnormal functioning in tissues. I love using a microscope, and I have always wanted to help the sick.

A challenge in many tissue studies is identifying which cells make which product. As a pediatric pathologist, I am pleased to contribute to several such co-localization studies involving lesions caused by immunological and cancerous cell changes.

I have won many awards for molecular pathology teaching, including multiple Gold Apple teaching awards from medical students, and multiple Clinical Pathology Teacher of the Year awards from residents. I have also received the Dean’s Award for Teaching Excellence from the College of Medicine.

Interests

Microscopic techniques for assessing mRNA expression; protein production and cellular identity in eukaryotic tissues; stem cell development and differentiation using animal models such as the zebrafish

Research Areas

Pathology

Publications

Identification of alternative protein targets of glutamate-ureido-lysine associated with PSMA tracer uptake in prostate cancer cells. Bakht, MK; Hayward, JJ; Shahbazi-Raz, F; Skubal, M; Tamura, R; Stringer, KF; Meister, D; Venkadakrishnan, VB; Xue, H; Pillon, A; Beltran, H; Grimm, J; Porter, LA; Trant, JF. Proceedings of the National Academy of Sciences of USA. 2022; 119:e2025710119.

Integration of Genomic Medicine in Pathology Resident Training. Haspel, RL; Genzen, JR; Wagner, J; Lockwood, CM; Fong, K; Adesina, AM; Browning, L; Chabot-Richards, D; Cushman-Vokoun, AM; D’Angelo, AR; Sobel, ME; Stringer, KF; Vanderbilt, CM; Young, M. American Journal of Clinical Pathology. 2020; 154:784-791.

Cyclin-like proteins tip regenerative balance in the liver to favour cancer formation. Fifield, B; Talia, J; Stoyanovich, C; Elliott, MJ; Bakht, MK; Basilious, A; Samsoondar, JP; Curtis, M; Stringer, KF; Porter, LA. Carcinogenesis. 2020; 41:850-862.

Differential Expression of Glucose Transporters and Hexokinases in Prostate Cancer with a Neuroendocrine Gene Signature: A Mechanistic Perspective for 18F-FDG Imaging of PSMA-Suppressed Tumors. Bakht, MK; Lovnicki, JM; Tubman, J; Stringer, KF; Chiaramonte, J; Reynolds, MR; Derecichei, I; Ferraiuolo, R; Fifield, B; Lubanska, D; Wang, Y; Ahmadzadehfar, H; Dong, X; Porter, LA. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2020; 61:904-910.

Juvenile OLFM4-null mice are protected from sepsis. Stark, JE; Opoka, AM; Mallela, J; Devarajan, P; Ma, Q; Levinsky, NC; Stringer, KF; Wong, HR; Alder, MN. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 2020; 318:F809-F816.

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4.6

Overall Patient Rating