A photo of Keith Stringer.

Keith F. Stringer, MD

  • Pathologist, Division of Pathology and Laboratory Medicine
  • Associate Professor, UC Department of Pediatrics

About

Biography

With my colleagues, I aim to decipher mechanisms of disease using a variety of microscopy techniques. I try to determine what abnormalities are present, as well as when and where. I am particularly interested in cancer biology, inflammatory response and musculoskeletal aberrations.

My path to research was paved by a curiosity about mysterious, small-scale failures that lead to abnormal functioning in tissues. I love using a microscope, and I have always wanted to help the sick.

A challenge in many tissue studies is identifying which cells make which product. As a pediatric pathologist, I am pleased to contribute to several such co-localization studies involving lesions caused by immunological and cancerous cell changes.

I have won many awards for molecular pathology teaching, including multiple Gold Apple teaching awards from medical students, and multiple Clinical Pathology Teacher of the Year awards from residents. I have also received the Dean’s Award for Teaching Excellence from the College of Medicine.

BSc: University of British Columbia, Vancouver, British Columbia, Canada.

MSc: University of Toronto, Toronto, Ontario, Canada.

MD: University of Calgary, Calgary, Alberta, Canada, 1995.

DABP: Anatomic and Pediatric Pathology.

Interests

Microscopic techniques for assessing mRNA expression; protein production and cellular identity in eukaryotic tissues; stem cell development and differentiation using animal models such as the zebrafish

Services and Specialties

Pathology

Research Areas

Pathology

Publications

Identification of alternative protein targets of glutamate-ureido-lysine associated with PSMA tracer uptake in prostate cancer cells. Bakht, MK; Hayward, JJ; Shahbazi-Raz, F; Skubal, M; Tamura, R; Stringer, KF; Meister, D; Venkadakrishnan, VB; Xue, H; Pillon, A; et al. Proceedings of the National Academy of Sciences of the United States of America. 2022; 119.

Integration of Genomic Medicine in Pathology Resident Training. Haspel, RL; Genzen, JR; Wagner, J; Lockwood, CM; Fong, K; Adesina, AM; Browning, L; Chabot-Richards, D; Cushman-Vokoun, AM; D’Angelo, AR; et al. American Journal of Clinical Pathology. 2020; 154:784-791.

Cyclin-like proteins tip regenerative balance in the liver to favour cancer formation. Fifield, B; Talia, J; Stoyanovich, C; Elliott, MJ; Bakht, MK; Basilious, A; Samsoondar, JP; Curtis, M; Stringer, KF; Porter, LA. Carcinogenesis. 2020; 41:850-862.

Differential Expression of Glucose Transporters and Hexokinases in Prostate Cancer with a Neuroendocrine Gene Signature: A Mechanistic Perspective for 18F-FDG Imaging of PSMA-Suppressed Tumors. Bakht, MK; Lovnicki, JM; Tubman, J; Stringer, KF; Chiaramonte, J; Reynolds, MR; Derecichei, I; Ferraiuolo, R; Fifield, B; Lubanska, D; et al. Journal of Nuclear Medicine. 2020; 61:904-910.

Juvenile OLFM4-null mice are protected from sepsis. Stark, JE; Opoka, AM; Mallela, J; Devarajan, P; Ma, Q; Levinsky, NC; Stringer, KF; Wong, HR; Alder, MN. American Journal of Physiology - Renal Physiology. 2020; 318:F809-F816.

Assessment of Enhanced Thermal Effect Due to Gold Nanoparticles during MR-Guided High-Intensity Focused Ultrasound (HIFU) Procedures Using a Mouse-Tumor Model. Devarakonda, SB; Stringer, K; Rao, M; Myers, M; Banerjee, R. ACS Biomaterials Science and Engineering. 2019; 5:4102-4111.

Neuroendocrine differentiation of prostate cancer leads to PSMA suppression. Bakht, MK; Derecichei, I; Li, Y; Ferraiuolo, R; Dunning, M; Oh, SW; Hussein, A; Youn, H; Stringer, KF; Jeong, CW; et al. Endocrine-Related Cancer. 2019; 26:131-146.

Sepsis Induces Adipose Tissue Browning in Nonobese Mice But Not in Obese Mice. Ayalon, I; Shen, H; Williamson, L; Stringer, K; Zingarelli, B; Kaplan, JM. Shock. 2018; 50:557-564.

Patient Ratings and Comments

All patient satisfaction ratings and comments are submitted by actual patients and verified by a leading independent patient satisfaction company, NRC Health. Patient identities are withheld to ensure confidentiality and privacy. Only those providers whose satisfaction surveys are administered through Cincinnati Children’s Hospital Medical Center are displayed. Click here to learn more about our survey