Rebecca Shaffer

Rebecca C. Shaffer, PsyD, HSPP


  • Clinical Psychologist, Division of Behavioral Medicine and Clinical Psychology
  • Professor, UC Department of Pediatrics

About

Biography

My biggest passion is seeing children with neurobehavioral disorders learn and grow through treatment. It is exciting when these children can engage in new activities or friendships based on the skills they learn, particularly when they learn to regulate their emotions and behaviors.

My research career has been dedicated to the treatment and research of neurobehavioral disorders, such as autism spectrum disorder (ASD), fragile X syndrome and Angelman syndrome. It is a pleasure for me to serve these children and their families.

My current career path began in general child psychology, but I became focused on neurobehavioral disorders during my fellowship and first faculty position at Indiana University (IU) School of Medicine. After my time at IU, I joined Cincinnati Children’s Hospital Medical Center and the Kelly O’Leary Autism Center. Currently, I serve as an associate professor of pediatrics with an affiliated appointment at the University of Cincinnati.

I have a commitment to training future leaders in neurobehavioral care. As the director of psychological services for the Cincinnati Fragile X Center, I oversee the assessment and treatment of individuals with fragile X syndrome. I also lead or assist with several fragile X research studies focused on parent training, outcome measurement and medication trials.

Emotional regulation is an area of need, especially in children with ASD. It is my strongest area of interest. Difficulties in emotional regulation make it hard for children to fully enjoy life and can place a huge burden on their families. My team has created an emotion regulation treatment program for children with ASD called Regulating Together.

Regulating Together treats emotion dysregulation, especially with reactivity and irritability, in a group setting with concurrent caregiver training. I currently lead several research studies, as well as publications, focused on the development and efficacy of this program. I also serve as the primary investigator of the Simons Foundation Powering Autism Research (SPARK) study at Cincinnati Children’s and other ASD-specific studies.

BS: Indiana Wesleyan University, Marion, IN.

MA: Chestnut Hill College, Philadelphia, PA.

PsyD: Chestnut Hill College, Philadelphia, PA.

Internship: Youth Opportunity Center, Muncie, IN.

Fellowship: Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN.

Interests

Autism spectrum disorders; fragile X; Angelman syndrome; parent training; social skills training; applied behavioral analysis

Interests

Eye tracking; autism spectrum disorders; fragile X; Angelman syndrome; parent training; social skills training; applied behavioral analysis.

Publications

Patterns in Medication Use for Treatment of Depression in Autistic Spectrum Disorder. Argonis, RA; Pedapati, EV; Dominick, KC; Harris, K; Lamy, M; Fosdick, C; Schmitt, L; Shaffer, RC; Smith, E; Will, M; McDougle, CJ; Erickson, CA. Journal of Autism and Developmental Disorders. 2025; 55:1969-1975.

Health Related Quality of Life in Autistic Youth and Their Families. Nelson, MA; Shaffer, RC; Schmitt, LM; Coffman, MC; Horn, PS; Reisinger, DL; Erickson, CA. Journal of Autism and Developmental Disorders. 2025; 55:1982-1987.

Frontal cortex hyperactivation and gamma desynchrony in Fragile X syndrome: Correlates of auditory hypersensitivity. Pedapati, EV; Ethridge, LE; Liu, Y; Liu, R; Sweeney, JA; DeStefano, LA; Miyakoshi, M; Razak, K; Schmitt, LM; Moore, DR; Dominick, KC; Horn, PS; Binder, D; Erickson, CA. PloS one. 2025; 20:e0306157.

Results from a Double-Blind, Randomized, Placebo-Controlled, Single-Dose, Crossover Trial of Lovastatin or Minocycline in Fragile X Syndrome. McKinney, WS; Schmitt, LM; De Stefano, LA; Ethridge, L; Norris, JE; Horn, PS; Dauterman, S; Rosselot, H; Pedapati, EV; Reisinger, DL; Friedman, NR; Hong, M; Sweeney, JA; Erickson, C. Journal of Child and Adolescent Psychopharmacology. 2025; 35:211-221.

A near normal distribution of IQ in Fragile X Syndrome. Schmitt, LM; Nelson, M; Shaffer, RC; Erickson, CA. Scientific Reports. 2024; 14:23058.

Examining the feasibility and utility of heart rate variability on intervention outcomes targeting emotion regulation in autism: a brief report. Reisinger, DL; Goodwin, MS; Horn, PS; Schmitt, LM; Coffman, MC; Shaffer, RC. Scientific Reports. 2024; 14:15409.

Telehealth regulating together pilot trial: emotion regulation intervention for autistic children and adolescents. Coffman, M; Wells, M; Schmitt, LM; Reisinger, DL; Horn, PS; Shaffer, RC. Frontiers in Psychiatry. 2024; 15:1401148.

Return of genetic research results in 21,532 individuals with autism. Wright, JR; Astrovskaya, I; Barns, SD; Goler, A; Zhou, X; Shu, C; Snyder, LA G; Han, B; Aarrestad, A; Abbeduto, L; Choi, YB; Clark, N; Clark, R; Coffman, M. Genetics in Medicine. 2024; 26:101202.

Training and Supporting Caregivers in Evidence-Based Practices. Kang, S; Minshawi, NF; Shaffer, RC. Handbook of Early Intervention for Autism Spectrum Disorders. : Springer Nature; Springer Nature; 2024.

Reliability of resting-state electrophysiology in fragile X syndrome. Liu, R; Pedapati, EV; Schmitt, LM; Shaffer, RC; Smith, EG; Dominick, KC; DeStefano, LA; Westerkamp, G; Horn, P; Sweeney, JA; Erickson, CA. Biomarkers in Neuropsychiatry. 2023; 9:100070.

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