A photo of Rhonda Szczesniak.

Associate Professor, UC Department of PediatricsUC Department of Environmental Health; UC Department of Mathematical Sciences


Biography & Affiliation


My research interests include predictive modeling, medical monitoring, lung diseases and disorders, biomarker discovery and longitudinal data analysis. In my research lab, the goals of my team include designing and analyzing medical monitoring investigations as well as incorporating biomarkers for customized, enhanced prediction/early detection of swift disease progression.

Some of the most notable discoveries made at my lab include identifying pediatric phenotypes of rapid lung disease progression using the Cystic Fibrosis Registry and the proteomics-informed prediction modeling of rapid lung disease progression.

I was led to my research interests by witnessing how certain things change over time and determining why things transform. This is why I pursued statistics in my graduate studies at the University of Kentucky.

As my career progressed, I received a recognition for biostatistical contributions to cystic fibrosis research in the Journal of Cystic Fibrosis in April 2019. I have also held reviewer positions on grant award panels and I hold a membership in the Cystic Fibrosis Foundation Patient Registry/Comparative Effectiveness Research Committee. My research has been supported by the National Institutes of Health (NIH) and the Cystic Fibrosis Foundation.

I have more than 12 years of experience in the biostatistics field, and I first started working at the Cincinnati Children’s Hospital Medical Center in 2007. Lastly, my research work has been published in a multitude of journals, including Statistics in Medicine, Journal of Religion and Health, Journal of Cystic Fibrosis, Journal of Diabetes Research, Annals of the American Thoracic Society, and American Journal of Respiratory and Critical Care Medicine.

Clinical Interests

Cystic fibrosis; blood pressure; glycemic control

Research Interests

Functional data analysis; longitudinal data analysis; medical monitoring; prediction

Academic Affiliation

Associate Professor, UC Department of PediatricsUC Department of Environmental Health; UC Department of Mathematical Sciences

Research Divisions



PhD: Statistics, University of Kentucky, Lexington, KY, 2007.

MS: Statistics, University of Kentucky, Lexington, KY, 2005.

BS: Mathematics, Radford University, Radford, VA, 2003.


Multivariate joint modeling to identify markers of growth and lung function decline that predict cystic fibrosis pulmonary exacerbation onset. Andrinopoulou, ER; Clancy, JP; Szczesniak, RD. BMC Pulmonary Medicine. 2020; 20.

Biclustering of medical monitoring data using a nonparametric hierarchical Bayesian model. Ren, Y; Sivaganesan, S; Altaye, M; Amin, RS; Szczesniak, RD. Stat. 2020; 9.

Integrating latent classes in the Bayesian shared parameter joint model of longitudinal and survival outcomes. Andrinopoulou, E; Nasserinejad, K; Szczesniak, R; Rizopoulos, D. Statistical Methods in Medical Research. 2020; 29:3294-3307.

Randomized trial of lung hyperinflation therapy in children with congenital muscular dystrophy. Sawnani, H; Mayer, OH; Modi, AC; Pascoe, JE; McConnell, K; McDonough, JM; Rutkowski, AM; Hossain, MM; Szczesniak, R; Tadesse, DG; et al. Pediatric Pulmonology. 2020; 55:2471-2478.

Precision Health Analytics With Predictive Analytics and Implementation Research: JACC State-of-the-Art Review. Pearson, TA; Califf, RM; Roper, R; Engelgau, MM; Khoury, MJ; Alcantara, C; Blakely, C; Boyce, CA; Brown, M; Croxton, TL; et al. Journal of the American College of Cardiology. 2020; 76:306-320.

Influences of environmental exposures on individuals living with cystic fibrosis. Szczesniak, R; Rice, JL; Brokamp, C; Ryan, P; Pestian, T; Ni, Y; Andrinopoulou, E; Keogh, RH; Gecili, E; Huang, R; et al. Expert Review of Respiratory Medicine. 2020; 14:737-748.

Assessing the Relationship between Gestational Glycemic Control and Risk of Preterm Birth in Women with Type 1 Diabetes: A Joint Modeling Approach. Gupta, R; Khoury, JC; Altaye, M; Jandarov, R; Szczesniak, RD. Journal of Diabetes Research. 2020; 2020:3074532-8.

Data driven decision making to characterize clinical personas of parents of children with cystic fibrosis: a mixed methods study. Szczesniak, RD; Pestian, T; Duan, LL; Li, D; Stamper, S; Ferrara, B; Kramer, E; Clancy, JP; Grossoehme, D. BMC Pulmonary Medicine. 2020; 20.

Transparency and open access in CF research. Stanojevic, S; Szczesniak, R. Journal of Cystic Fibrosis. 2020; 19:e13-e13.

Dynamic predictive probabilities to monitor rapid cystic fibrosis disease progression. Szczesniak, RD; Su, W; Brokamp, C; Keogh, RH; Pestian, JP; Seid, M; Diggle, PJ; Clancy, JP. Statistics in Medicine. 2020; 39:740-756.