A photo of Sara Szabo.

Staff Pathologist, Division of Pathology

Director, Oncopathology

Professor, UC Department of Pathology and Laboratory MedicineUC Department of Pediatrics

513-803-8570

Board Certified

"While I’m mostly invisible to families, I do enjoy the trust of my clinician colleagues and like to hear how their patients are doing."

My Biography & Research

Biography

Curiosity about nature’s mysteries drove me to the sciences in my teens, with the thrill of small daily discoveries as I tinkered in my mother’s kitchen or my father’s workshop. Yet, my grandfather saw me as a future pediatrician, as a “lady doctor” caring for the neighborhood’s babies and children. Since then, I’ve walked a meandering professional path in diagnostics — from radiology, through molecular virology to pediatric pathology. My daily thrill now comes from correlative diagnostics, working with clinicians to provide personalized care for children and young adults.

My routine clinical work is microscopy-based, with molecular diagnostics, which is salient to data-driven discovery with researchers and is driving better care for every patient we see. In other words: It is an engine of personalized medicine and a motivator for me as a physician.

I make comprehensive diagnoses, focusing on tumors arising in soft tissues and bones, pediatric tumors of abdominal and thoracic organs, and of vascular tumors and malformations. While I’m mostly invisible to families, I do enjoy the trust of my clinician colleagues and like to hear how their patients are doing.

An award that is personal to me was one I received 2015 — the Society for Pediatric Pathology President’s Distinguished Colleague Award. It bespoke of Dr. Kapur’s humanity, collegiality and professional philosophy as a pediatric pathologist.

In research, I've teamed up with clinical and basic scientists to advance therapy for:

  • Soft tissue tumors such as rhabdomyosarcomas and neurofibromatosis
  • Vascular malformations
  • Inflammatory conditions in fatty liver disease (NAFLD)
  • Bone marrow transplantation

This work transforms our personal and team practices. I sometimes joke that I’m a neighborhood pathologist-scientist to serious basic scientists.

In my free time, I dance free-style while cardio-kickboxing and “kick” while dancing. I dream of creating a chocolate shop, with neighborhood photos and children’s portraits.

Additional Languages

Hungarian

Clinical Interests

Pediatric pathology; pathology and genetics of soft tissue and bone tumors

Research Interests

Pathology and genetics of soft tissue and bone tumors, vascular anomalies, and select inflammatory disorders

Academic Affiliation

Professor, UC Department of Pathology and Laboratory MedicineUC Department of Pediatrics

Clinical Divisions

Pathology, Hemangioma and Vascular Malformations

Research Divisions

Pathology

My Education

MD: University of Pecs Medical School, Pecs, Hungary, 1983-1989.

PhD: Tulane University, New Orleans, LA, 1992-1998.

Fellowship: Pediatric Pathology, Texas Children’s Hospital and Baylor College of Medicine, Houston, TX, 2003-2004.

Board Certifications: Anatomic and Clinical Pathology, The American Board of Pathology, 2003; Pediatric Pathology, The American Board of Pathology, 2005.

State Licensure (Active): Ohio, Wisconsin, Louisiana.

My Publications

Cdkn2a Loss in a Model of Neurofibroma Demonstrates Stepwise Tumor Progression to Atypical Neurofibroma and MPNST. Chaney, KE; Perrino, MR; Kershner, LJ; Patel, AV; Wu, J; Choi, K; Rizvi, TA; Dombi, E; Szabo, S; Largaespada, DA; et al. Cancer Research. 2020; 80:4720-4730.

Solitary myofibroma preceding the development of multicentric myofibromatosis: A report of two cases with surveillance recommendations. Todd, K; Kim, HK; Szabo, S; Johnson, S; Pressey, J; Nagarajan, R; Sorger, J; Dasgupta, R; Turpin, B. Pediatric Blood and Cancer. 2020; 67.

Genome-driven therapy for chemotherapy-resistant metastatic CDK6-amplified osteosarcoma. Lazow, MA; Johnson, SL; Johnson, ND; Breneman, JC; Dexheimer, PJ; Szabo, S; Pressey, JG. JCO Precision Oncology. 2020; 4:498-504.

Small cell carcinoma of the ovary hypercalcemic type (SCCOHT): Comprehensive management of a newly diagnosed young adult. Pressey, JG; Dandoy, CE; Pater, LE; Rios, JS; Sisson, R; Dasgupta, R; Szabo, S. Gynecologic Oncology. 2020; 158:538-546.

Pediatric BRAF (V600E)-mutated pancreatic acinar cell carcinoma with complete and durable response to dabrafenib and trametinib. Cramer, S; Marcus, MA; Ramkissoon, S; Szabo, S; Pressey, JG. JCO Precision Oncology. 2020; 4:801-805.

A case of submandibular desmoplastic small round cell tumor: Diagnostic and management approaches to an atypical presentation of a rare tumor. Rubinstein, JD; Gupta, A; Szabo, S; Pressey, JG. Pediatric Blood and Cancer. 2020; 67.

CD244 represents a new therapeutic target in head and neck squamous cell carcinoma. Agresta, L; Lehn, M; Lampe, K; Cantrell, R; Hennies, C; Szabo, S; Wise-Draper, T; Conforti, L; Hoebe, K; Janssen, EM. Journal for ImmunoTherapy of Cancer. 2020; 8:e000245-e000245.

Hemophagocytic lymphohistiocytosis mimicking neonatal hemochromatosis. Broglie, L; Vitola, B; Thakar, MS; Basel, D; Szabo, S; Agni, R; Talano, J. Pediatric Hematology-Oncology (Informa). 2019; 36:451-456.

Targeted Inhibition of the Dual Specificity Phosphatases DUSP1 and DUSP6 Suppress MPNST Growth via JNK. Ramkissoon, A; Chaney, KE; Milewski, D; Williams, KB; Williams, RL; Choi, K; Miller, A; Kalin, TV; Pressey, JG; Szabo, S; et al. Clinical Cancer Research. 2019; 25:clincanres.3224.2018-clincanres.3224.2018.

Expanding the Spectrum of Pediatric NTRK-rearranged Mesenchymal Tumors. Davis, JL; Lockwood, CM; Stohr, B; Boecking, C; Al-Ibraheemi, A; DuBois, SG; Vargas, SO; Black, JO; Cox, MC; Luquette, M; et al. American Journal of Surgical Pathology. 2019; 43:435-445.