Steve Standage, MD
- Attending Physician, Pediatric Intensive Care Unit (PICU)
- Director of Research Informatics, Pediatric Critical Care Medicine
- Associate Professor, UC Department of Pediatrics
- steve.standage@cchmc.org
- Board Certified
About
Biography
Medicine, for me, is the perfect synthesis of long-held passions I have for service to others, caring for children, and understanding the natural world. In the pediatric intensive care unit, I have the great privilege of weaving threads of knowledge, experience, and expertise to help support kids and their families during some of the most difficult moments of their lives. Teaching physicians of the rising generation gives me great satisfaction. I love to investigate the molecular biology, physiology, and medical science that underpin critical illness and provide hope of improving outcomes.
For years, I studied the immunologic and metabolic pathophysiology of sepsis-induced organ system failure in the laboratory. More recently, I have pivoted my academic focus toward research data management for basic, translational, and clinical studies. I help pull data from clinical and analytical sources, transform and organize it, and carefully analyze it. If science is built on close observation of natural phenomena, then we need to carefully curate records of our observations for the knowledge we hope to derive from that information to be valid and clinically impactful.
BS: Brigham Young University, Provo, UT, 2001.
MD: University of Rochester School of Medicine, Rochester, NY, 2005.
Residency: General Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, 2008.
Fellowship: Pediatric Critical Care, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2011.
Certificate: Applied Biostatistics, University of Washington; Seattle, WA, 2017.
Summer Institute in Statistics for Big Data: University of Washington; Seattle, WA, 2017.
Certifications: Epic Physician Builder, Advanced and Analytics Certifications; Epic University; Verona, WI, 2023.
Board Certification: General Pediatrics, 2008.
Board Certification: Pediatric Critical Care Medicine, 2012.
Interests
Pediatric critical care
Services and Specialties
Interests
Basic, translational, and clinical research informatics; sepsis and septic shock; acute respiratory distress syndrome; acute kidney failure; immunologic and metabolic mechanisms of sepsis-induced organ failure
Research Areas
Additional Languages
SpanishPublications
Identification and transcriptomic assessment of latent profile pediatric septic shock phenotypes. Critical Care (UK). 2024; 28:246.
Diagnostic Validation of the Updated Pediatric Sepsis Biomarker Risk II for Acute Kidney Injury Prediction Model in Pediatric Septic Shock. Pediatric Critical Care Medicine. 2024; 25:1005-1016.
Detrimental effects of PCSK9 loss-of-function in the pediatric host response to sepsis are mediated through independent influence on Angiopoietin-1. Critical Care (UK). 2023; 27:250.
External validation of the modified sepsis renal angina index for prediction of severe acute kidney injury in children with septic shock. Critical Care (UK). 2023; 27:463.
First-Time Use of the Seraph® 100 Microbind® Affinity Blood Filter in an Adolescent Patient with Severe COVID-19 Disease: A Case Report. Case Reports in Nephrology and Dialysis. 2023; 13:1-6.
Choline supplementation attenuates experimental sepsis-associated acute kidney injury. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 2022; 323:F255-F271.
Candidate Biomarkers for Sepsis-Associated Acute Kidney Injury Mechanistic Studies. Shock. 2022; 57:687-693.
Multi-Organ Transcriptome Dynamics in a Mouse Model of Cecal Ligation and Puncture-Induced Polymicrobial Sepsis. Journal of Inflammation Research. 2021; 14:2377-2388.
NMR-based serum and urine metabolomic profile reveals suppression of mitochondrial pathways in experimental sepsis-associated acute kidney injury. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 2021; 320:F984-F1000.
From the Blog
Cincinnati Children’s Launches 6 COVID-19 Research Projects
Steve Standage, MD, Ming Tan, PhD ...5/26/2020
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