Jason C. Woods, PhD
- Director of Research, Division of Pulmonary Medicine
- Co-Director, Bronchopulmonary Dysplasia Center
- Professor, UC Department of Pediatrics
- UC Department of Radiology
About
Biography
My interest in pulmonary imaging research was born of a unique background in hyperpolarized gases and atomic physics, combined with an interest in translational applications to surgery and pulmonary medicine.
My primary research areas include pulmonary MRI, regional structure-function relationships, pathophysiology, translational imaging research and clinical trials. The overall goal of this research is to improve outcomes for patients with lung disease through precise imaging and determination of regional structure-function relationships, using a combination of translational techniques and innovative methodologies.
We have pioneered 129Xe MRI in pediatrics and help lead the 129Xe MRI Clinical Trials Consortium. We also have begun to redefine bronchopulmonary dysplasia (BPD) by imaging-phenotypes, which show a direct relationship to outcomes.
Our research team is comprised of experts in hyperpolarized-gas MRI and in the use of this technique to measure regional lung function, physiology and microstructure. Many of the fellows and junior faculty that I have mentored have won awards and recognition from national and international organizations, such as the International Society for Magnetic Resonance in Medicine (ISMRM), the American Thoracic Society (ATS) and the Society for Pediatric Radiology (SPR).
Since my arrival at Cincinnati Children’s in 2013, I’ve served as the director of the Center for Pulmonary Imaging Research (CPIR). Our center offers a multidisciplinary research and training program that combines pulmonary medicine, radiology and neonatology. I also co-lead the Bronchopulmonary Dysplasia Center at Cincinnati Children’s, where imaging research has been rapidly translated into clinical care and improved patient outcomes.
PhD: Washington University, St. Louis, MO, 2002.
Postdoctoral: Washington University, St. Louis, MO, 2004.
Interests
Bronchopulmonary dysplasia
Interests
Hyperpolarized gas; pulmonary MRI; translational studies; image-guided pulmonary interventions
Research Areas
Pulmonary Medicine, Imaging, Fibrosis
Publications
Evaluation of regional lung mass and growth in neonates with bronchopulmonary dysplasia using ultrashort echo time magnetic resonance imaging. Pediatric Pulmonology. 2024; 59:55-62.
Insights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasis. Nature Communications. 2023; 14:1205.
Improved donor lung size matching by estimation of lung volumes based on chest X-ray measurements. Pediatric Transplantation. 2023; 27:e14594.
Initial feasibility and challenges of hyperpolarized 129 Xe MRI in neonates with bronchopulmonary dysplasia. Magnetic Resonance in Medicine. 2023; 90:2420-2431.
302 Clinical response to modulator therapy in patients homozygous for G27V CFTR. Journal of Cystic Fibrosis. 2023; 22:s152.
57 Bronchoscopy sampling finds that intra-lung bacterial migration contributes to persistent Pseudomonas aeruginosa infection after elexacaftor-tezacaftor-ivacaftor. Journal of Cystic Fibrosis. 2023; 22:s31.
Intra- and Inter-visit Repeatability of 129 Xenon Multiple-Breath Washout MRI in Children With Stable Cystic Fibrosis Lung Disease. Journal of Magnetic Resonance Imaging. 2023; 58:936-948.
Short-term structural and functional changes after airway clearance therapy in cystic fibrosis. Journal of Cystic Fibrosis. 2023; 22:926-932.
MRI assessment and guidance for regionally targeted pulmonary interventions. Pediatric Pulmonology. 2023; 58:2386-2388.
Phase-Contrast Magnetic Resonance Imaging of Inhaled Xenon Reveals the Relationship between Airflow and Obstruction in Obstructive Sleep Apnea. American Journal of Respiratory and Critical Care Medicine. 2023; 208:e5-e6.
From the Blog
3333 Burnet Avenue, Cincinnati, Ohio 45229-3026
© 1999-2024 Cincinnati Children's Hospital Medical Center. All rights reserved.
