A photo of Jason Woods.

Director, Center for Pulmonary Imaging Research

Professor, UC Department of PediatricsUC Department of Radiology

513-803-4463

Biography & Affiliation

Biography

My interest in pulmonary imaging research was born of a unique background in hyperpolarized gases and atomic physics, combined with an interest in translational applications to surgery and pulmonary medicine.

My primary research areas include pulmonary MRI, regional structure-function relationships, pathophysiology, translational imaging research and clinical trials. The overall goal of this research is to improve outcomes for patients with lung disease through precise imaging and determination of regional structure-function relationships, using a combination of translational techniques and innovative methodologies.

We have pioneered 129Xe MRI in pediatrics and help lead the 129Xe MRI Clinical Trials Consortium. We also have begun to redefine bronchopulmonary dysplasia (BPD) by imaging-phenotypes, which show a direct relationship to outcomes.

Our research team is comprised of experts in hyperpolarized-gas MRI and in the use of this technique to measure regional lung function, physiology and microstructure. Many of the fellows and junior faculty that I have mentored have won awards and recognition from national and international organizations, such as the International Society for Magnetic Resonance in Medicine (ISMRM), the American Thoracic Society (ATS) and the Society for Pediatric Radiology (SPR).

Since my arrival at Cincinnati Children’s in 2013, I’ve served as the director of the Center for Pulmonary Imaging Research (CPIR). Our center offers a multidisciplinary research and training program that combines pulmonary medicine, radiology and neonatology. I also co-lead the Bronchopulmonary Dysplasia Center at Cincinnati Children’s, where imaging research has been rapidly translated into clinical care and improved patient outcomes.

Research Interests

Hyperpolarized gas; pulmonary MRI; translational studies; image-guided pulmonary interventions

Academic Affiliation

Professor, UC Department of PediatricsUC Department of Radiology

Research Divisions

Pulmonary Medicine, Imaging, Fibrosis

Education

PhD: Washington University, St. Louis, MO, 2002.

Postdoctoral: Washington University, St. Louis, MO, 2004.

Publications

Cardiovascular magnetic resonance imaging derived septal curvature in neonates with bronchopulmonary dysplasia associated pulmonary hypertension. Critser, PJ; Higano, NS; Lang, SM; Kingma, PS; Fleck, RJ; Hirsch, R; Taylor, MD; Woods, JC. Journal of Cardiovascular Magnetic Resonance. 2020; 22.

The effect of airway motion and breathing phase during imaging on CFD simulations of respiratory airflow. Gunatilaka, CC; Schuh, A; Higano, NS; Woods, JC; Bates, AJ. Computers in Biology and Medicine. 2020; 127:104099-104099.

Current state of the art MRI for the longitudinal assessment of cystic fibrosis. Woods, JC; Wild, JM; Wielpuetz, MO; Clancy, JP; Hatabu, H; Kauczor, H; van Beek, EJ R; Altes, TA. Journal of Magnetic Resonance Imaging. 2020; 52:1306-1320.

A semi-empirical model to optimize continuous-flow hyperpolarized 129Xe production under practical cryogenic-accumulation conditions. Plummer, JW; Emami, K; Dummer, A; Woods, JC; Walkup, LL; Cleveland, ZI. Journal of Magnetic Resonance. 2020; 320:106845-106845.

Volumetric quantification of lung MR signal intensities using ultrashort TE as an automated score in cystic fibrosis. Benlala, I; Point, S; Leung, C; Berger, P; Woods, JC; Raherison, C; Laurent, F; Macey, J; Dournes, G. European Radiology. 2020; 30:5479-5488.

Magentic Resonance Imaging Evaluation of Regional Lung VTs in Severe Neonatal Bronchopulmonary Dysplasia. Gouwens, KR; Higano, NS; Marks, KT; Stimpfl, JN; Hysinger, EB; Woods, JC; Kingma, PS. American Journal of Respiratory and Critical Care Medicine. 2020; 202:1024-1031.

Increased Work of Breathing due to Tracheomalacia in Neonates. Gunatilaka, CC; Higano, NS; Hysinger, EB; Gandhi, DB; Fleck, RJ; Hahn, AD; Fain, SB; Woods, JC; Bates, AJ. Annals of the American Thoracic Society. 2020; 17:1247-1256.

Lung microstructure in adolescent idiopathic scoliosis before and after posterior spinal fusion. Thomen, RP; Woods, JC; Sturm, PF; Jain, V; Walkup, LL; Higano, NS; Quirk, JD; Varisco, BM. PLoS ONE. 2020; 15:e0240265-e0240265.

Structural lung abnormalities on computed tomography correlate with asthma inflammation in bronchoscopic alveolar lavage fluid. Roach, DJ; Ruangnapa, K; Fleck, RJ; Rattan, MS; Hossain, MM; Guilbert, TW; Woods, JC. Journal of Asthma (Informa). 2020; 57:968-979.

Single-session bronchial thermoplasty guided by 129xe magnetic resonance imaging a pilot randomized controlled clinical trial. Hall, CS; Quirk, JD; Goss, CW; Lew, D; Kozlowski, J; Thomen, RP; Woods, JC; Tustison, NJ; III, MJ P; Gallagher, L; et al. American Journal of Respiratory and Critical Care Medicine. 2020; 202:524-534.