Jason Woods

Jason C. Woods, PhD

  • Director of Research, Division of Pulmonary Medicine
  • Co-Director, Bronchopulmonary Dysplasia Center
  • Professor, UC Department of Pediatrics
  • UC Department of Radiology
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About

Biography

My interest in pulmonary imaging research was born of a unique background in hyperpolarized gases and atomic physics, combined with an interest in translational applications to surgery and pulmonary medicine.

My primary research areas include pulmonary MRI, regional structure-function relationships, pathophysiology, translational imaging research and clinical trials. The overall goal of this research is to improve outcomes for patients with lung disease through precise imaging and determination of regional structure-function relationships, using a combination of translational techniques and innovative methodologies.

We have pioneered 129Xe MRI in pediatrics and help lead the 129Xe MRI Clinical Trials Consortium. We also have begun to redefine bronchopulmonary dysplasia (BPD) by imaging-phenotypes, which show a direct relationship to outcomes.

Our research team is comprised of experts in hyperpolarized-gas MRI and in the use of this technique to measure regional lung function, physiology and microstructure. Many of the fellows and junior faculty that I have mentored have won awards and recognition from national and international organizations, such as the International Society for Magnetic Resonance in Medicine (ISMRM), the American Thoracic Society (ATS) and the Society for Pediatric Radiology (SPR).

Since my arrival at Cincinnati Children’s in 2013, I’ve served as the director of the Center for Pulmonary Imaging Research (CPIR). Our center offers a multidisciplinary research and training program that combines pulmonary medicine, radiology and neonatology. I also co-lead the Bronchopulmonary Dysplasia Center at Cincinnati Children’s, where imaging research has been rapidly translated into clinical care and improved patient outcomes.

PhD: Washington University, St. Louis, MO, 2002.

Postdoctoral: Washington University, St. Louis, MO, 2004.

Interests

Bronchopulmonary dysplasia

Services and Specialties

Interests

Hyperpolarized gas; pulmonary MRI; translational studies; image-guided pulmonary interventions

Research Areas

Publications

A Systematic Review of the Variability of Ventilation Defect Percent Generated From Hyperpolarized Noble Gas Pulmonary Magnetic Resonance Imaging. Diamond, VM; Bell, LC; Bone, JN; Driehuys, B; Menchaca, M; Santyr, G; Svenningsen, S; Thomen, RP; Marshall, H; Smith, LJ; Woods, JC; Fain, SB; Eddy, RL; Rayment, JH. Journal of Magnetic Resonance Imaging. 2025; 62:625-639.

Pseudomonas infections persisting after CFTR modulators are widespread throughout the lungs and drive lung inflammation. Durfey, SL; Kapnadak, SG; Pena, T; Willmering, MM; Godwin, JD; Teresi, ME; Heltshe, SL; Vo, AT; Villacreses, RA; Aliukonyte, I; Tiddens, HA W M; Woods, JC; Stoltz, DA; Singh, PK. Cell Host and Microbe. 2025; 33:S1931-3128(25)00281-1.

Community respiratory viruses are generally welltolerated in hematopoietic stem cell transplant recipients: a brief report from the TRANSPIRE study. Haney, M; Ashraf, A; Lake, KE; Strecker, L; Myers, KC; Towe, C; Walkup, L; Woods, J; Edwards, SL; Cooper, R; Goldfarb, SB; Davies, SM; Koo, J; Groups, T. Haematologica: the hematology journal. 2025; 110:1882-1886.

High Prevalence of Abnormal Baseline Lung Function in Pediatric and Young Adult Hematopoietic Stem Cell Transplant Recipients: A Report from the TRANSPIRE Study. Koo, J; Cooper, R; Edwards, SL; Lane, A; Loveless, SK; Strecker, L; Lake, KE; Myers, KC; Towe, C; Patti, J; Li, M; Goldfarb, SB; Woods, JC; Davies, SM. Pediatric Blood and Cancer. 2025; e31916.

Application of the defect distribution index to functional lung MRI of pediatric cystic fibrosis lung disease and controls. Kieninger, E; Munidasa, S; Curdy, M; Streibel, C; Zanette, B; Woods, J; Latzin, P; Ratjen, F; Santyr, G. Journal of Cystic Fibrosis. 2025; 24:809-815.

Chronic Pediatric Lung Diseases: Counterpoint-A Growing Role for MRI. Dournes, G; Woods, JC. American Journal of Roentgenology. 2025; 224:e2432405.

Association of Early Nutrition with Bronchopulmonary Dysplasia Severity and Magnetic Resonance Imaging Lung Characteristics in Preterm Infants. Dianova, E; Higano, NS; McNelis, KM; Ehrlich, SR; Liu, C; Woods, JC; Kingma, PS. Neonatology: foetal and neonatal research. 2025; 122:319-328.

Computational Fluid Dynamics Analysis of Tracheal Pressure Difference in Neonates With Tracheoesophageal Fistulas Before and After Surgical Repair. Boles, C; Gunatilaka, CC; Xiao, Q; Woods, JC; Kingma, PS; Higano, NS; Bates, A. American Journal of Respiratory and Critical Care Medicine. 2025; 211:a5119.

Frequency of Various Combinations of Static and Dynamic Airway Findings From Flexible Bronchoscopy in Patients With Trisomy 21. Lyman, BC; Burg, G; Woods, JC. American Journal of Respiratory and Critical Care Medicine. 2025; 211:a2301.

Pulmonary 129 Xe Ventilation MRI Predicts Severe Exacerbations in People With CF. Matheson, AM; Bdaiwi, AS; Willmering, M; DiFrancesco, MW; Cleveland, ZI; Woods, JC. American Journal of Respiratory and Critical Care Medicine. 2025; 211:a7088.

From the Blog

Xenon MRI launches at Cincinnati Children’s
Imaging Sciences

Xenon MRI launches at Cincinnati Children’s

Jason C. Woods, PhD5/12/2023

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