High Res

Jason C. Woods, PhD

Director, Center for Pulmonary Imaging Research

Academic Affiliations

Professor, UC Department of Pediatrics

UC Department of Radiology

Phone 513-803-4463

Email jason.woods@cchmc.org

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Research Interests

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Hyperpolarized gas; pulmonary MRI; translational studies; image-guided pulmonary interventions

Visit the Center for Pulmonary Imaging Research Lab.

Biography

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Dr. Woods is one of the world’s experts on hyperpolarized-gas MRI and the use of such gas MRI to measure regional lung function, microstructure and physiology. He began his career in physics, radiology, and the dean's office at Washington University in St Louis, and moved to Cincinnati Children's in 2013 to apply new imaging techniques to pediatric translational research. He leads multiple team projects related to the multidisciplinary study of lung structure, function, biology and physiology. In particular, imaging applications to the study of cystic fibrosis, BPD, rare-lung diseases, and allograft rejection are all active areas of current research.

Dr. Woods directs the Center for Pulmonary Imaging Research at Cincinnati Children’s Hospital Medical Center. The center is a multidisciplinary research and training program at the intersection of pulmonary medicine, radiology, and neonatology.

Education and Training

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PhD: Washington University, St. Louis, MO, 2002.

Postdoctoral: Washington University, St. Louis, MO, 2004.

Publications

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View PubMed Publications

Higano NS, Spielberg DR, Fleck RF, Schapiro AH, Walkup LL, Hahn AD, Tkach JA, Kingma PS, Merhar SL, Fain SB, Woods JC. Neonatal pulmonary MRI of bronchopulmonary dysplasia predicts short-term clinical outcomes. Am J Respir Crit Care Med. 2018 May 23.

Woods JC, Conradi MS. 3He Diffusion MRI in Human Lungs. J Magn Reson. 2018 Jul;292:90-98.

Pennati F, Roach DJ, Clancy JP, Brody AS, Fleck RJ, Aliverti A, Woods JC. Assessment of pulmonary structure-function relationships in young children and adolescents with cystic fibrosis by multi-volume proton MRI and CT. J Magn Reson Imag. 2018 Feb 19.

Higgins RD, Jobe AH, Koso-Thomas M, Bancalari E, Viscardi RM, Hartert TV, Ryan RM, Kallapur SG, Steinhorn RH, Konduri GG, Davis SD, Thebaud B, Clyman RI, Collaco JM, Martin CR, Woods JC, Finer NN, Raju TNK. Executive summary of the workshop on bronchopulmonary dysplasia. J Pediatrics. 2018 Jun;197:300-308.

Higano NS, Walkup LL, Spielberg DS, Hahn AD, Thomen RP, Merhar SL, Kingma PS, Tkach JA, Fain SB, Woods JC. Quantification of neonatal lung parenchymal density via ultrashort echo time MRI with comparison to CT. J Magn Reson Imag. 2017;46:992-1000.

Schopper MA, Walkup LL, Tkach JA, Higano NS, Lim FY, Haberman B, Woods JC, Kingma PS. Evaluation of neonatal lung growth in congenital diaphragmatic hernia by pulmonary MRI. J Pediatr. 2017;188:96-102.e1.

Cleveland ZI, Zhou YM, Akinyi TG, Dunn RS, Davidson CR, Guo J, Woods JC, Hardie WD. Magnetic Resonance Imaging of Disease Progression and Resolution in Transgenic Mouse Model of Pulmonary Fibrosis. Am J Physiol Lung Cell Mol Physiol. 2017;312:L488-L499

Trivedi A, Hall C, Gierada DS, Hoffman E, Woods JC, Castro M. Using Imaging as a Biomarker for Asthma. J Allergy Clin Immunol. 2017;139:1-10.

Thomen RP, Quirk JD, Roach DA, Ruppert K, Altes T, Yusen RW, Egan-Rojas T, Yablonskiy DA, Woods JC. Direct comparison of 129Xe diffusion measurements with quantitative histology in human lungs. Magn Reson Med. 2017;77:265-272.

Thomen RP, Walkup LL, Roach DJ, Cleveland ZI, Clancy JP, Woods JC. Hyperpolarized 129Xe for investigation of mild cystic fibrosis lung disease in pediatrics. J Cyst Fibros. 2017;46:992-1000.

Grants

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A Phase III Trial to Validate HP 129Xe MRI as a Functional Pulmonary Biomarker in Pediatric Lung Disease. Academic Principal Investigator. National Heart, Lung, and Blood Institute. Jul 2016–Jun 2019.

Developmental Mechanisms of Trachea-Esophageal Birth Defects. Investigator. National Institute of Child and Human Development. Sept 2017–Aug 2022.

Multicenter Interventional Lymphangioleiomyomatosis Early Disease Trial (MILED Trial)-CCC. Investigator. National Institute of General Medical Sciences. Sept 2016-Aug 2021.

UTE MRI to monitor CF lung disease and responses to CF TR modulation young children. Principal Investigator. National Heart, Lung, and Blood Institute. June 2016–May 2021.

Pathogenesis-Driven Therapeutic Development for Pulmonary Alveolar Microlithiasis. Investigator. National Heart, Lung, and Blood Institute. Sep 2016–Aug 2021.

Regional Biomarkers of Peripheral Lung Disease in Cystic Fibrosis. Investigator. Cystic Fibrosis Foundation. Apr 2016–Mar 2019.

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