Jason C. Woods, PhD
- Member, Division of Pulmonary Medicine
- Co-Director, Bronchopulmonary Dysplasia Center
- Professor, UC Department of Pediatrics
- UC Department of Radiology
About
Biography
My interest in pulmonary imaging research was born of a unique background in hyperpolarized gases and atomic physics, combined with an interest in translational applications to surgery and pulmonary medicine.
My primary research areas include pulmonary MRI, regional structure-function relationships, pathophysiology, translational imaging research and clinical trials. The overall goal of this research is to improve outcomes for patients with lung disease through precise imaging and determination of regional structure-function relationships, using a combination of translational techniques and innovative methodologies.
We have pioneered 129Xe MRI in pediatrics and help lead the 129Xe MRI Clinical Trials Consortium. We also have begun to redefine bronchopulmonary dysplasia (BPD) by imaging-phenotypes, which show a direct relationship to outcomes.
Our research team is comprised of experts in hyperpolarized-gas MRI and in the use of this technique to measure regional lung function, physiology and microstructure. Many of the fellows and junior faculty that I have mentored have won awards and recognition from national and international organizations, such as the International Society for Magnetic Resonance in Medicine (ISMRM), the American Thoracic Society (ATS) and the Society for Pediatric Radiology (SPR).
Since my arrival at Cincinnati Children’s in 2013, I’ve served as the director of the Center for Pulmonary Imaging Research (CPIR). Our center offers a multidisciplinary research and training program that combines pulmonary medicine, radiology and neonatology. I also co-lead the Bronchopulmonary Dysplasia Center at Cincinnati Children’s, where imaging research has been rapidly translated into clinical care and improved patient outcomes.
PhD: Washington University, St. Louis, MO, 2002.
Postdoctoral: Washington University, St. Louis, MO, 2004.
Interests
Bronchopulmonary dysplasia
Interests
Hyperpolarized gas; pulmonary MRI; translational studies; image-guided pulmonary interventions
Publications
Comparative evaluation of supervised and unsupervised deep learning strategies for denoising hyperpolarized 129Xe lung MRI. Magnetic Resonance in Medicine. 2026; 95(1):138-156.
How early should CFTR modulators be initiated to prevent structural cystic fibrosis lung disease? The Lancet Respiratory Medicine. 2026; 14(1):5-6.
Structural and Functional Lung Assessment in Neonates With Moderate to Severe Bronchopulmonary Dysplasia Using 3D Ultra-Short Echo Time MRI. Journal of Magnetic Resonance Imaging. 2025.
Multicenter Study of Hyperpolarized Xenon Magnetic Resonance Imaging in Children with Cystic Fibrosis Following Initiation of Cystic Fibrosis Transmembrane Regulator Modulator Therapy (HyPOINT). Annals of the American Thoracic Society. 2025; 22(12):1891-1899.
Tracheal Work of Breathing in Neonates With Tracheoesophageal Fistula Before and After Surgical Repair via Computational Fluid Dynamics Assessment. Journal of Pediatric Surgery. 2025; 60(12):162630.
Comparison of phase-resolved functional lung (PREFUL) and hyperpolarized 129Xe MRI for longitudinal monitoring of lung function in pediatric cystic fibrosis following elexacaftor/tezacaftor/ivacaftor. Pediatric Radiology. 2025; 55(13):2800-2812.
Structural and Functional Pulmonary MRI to Predict Pulmonary Exacerbations in Cystic Fibrosis. Chest. 2025.
Serial MRI Measures Short-term Parenchymal Changes in Neonatal Bronchopulmonary Dysplasia. Chest. 2025.
Evaluating Stack-of-Stars and FLORET 3D Ultrashort Echo Time MRI to Assess Structural Pathology in Cystic Fibrosis Lung Disease. Academic Radiology. 2025.
Hydroxyapatite microspheres induce durable pleurodesis and are rapidly cleared by pleural osteoclasts. JCI Insight. 2025; 10(19).
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