A photo of Jason Woods.

Director, Center for Pulmonary Imaging Research

Co-Director, Bronchopulmonary Dysplasia Center; Luther Foundation Research Chair in Pediatric Pulmonary Medicine

Professor, UC Department of PediatricsUC Department of Radiology

513-803-4463

Biography & Affiliation

Biography

My interest in pulmonary imaging research was born of a unique background in hyperpolarized gases and atomic physics, combined with an interest in translational applications to surgery and pulmonary medicine.

My primary research areas include pulmonary MRI, regional structure-function relationships, pathophysiology, translational imaging research and clinical trials. The overall goal of this research is to improve outcomes for patients with lung disease through precise imaging and determination of regional structure-function relationships, using a combination of translational techniques and innovative methodologies.

We have pioneered 129Xe MRI in pediatrics and help lead the 129Xe MRI Clinical Trials Consortium. We also have begun to redefine bronchopulmonary dysplasia (BPD) by imaging-phenotypes, which show a direct relationship to outcomes.

Our research team is comprised of experts in hyperpolarized-gas MRI and in the use of this technique to measure regional lung function, physiology and microstructure. Many of the fellows and junior faculty that I have mentored have won awards and recognition from national and international organizations, such as the International Society for Magnetic Resonance in Medicine (ISMRM), the American Thoracic Society (ATS) and the Society for Pediatric Radiology (SPR).

Since my arrival at Cincinnati Children’s in 2013, I’ve served as the director of the Center for Pulmonary Imaging Research (CPIR). Our center offers a multidisciplinary research and training program that combines pulmonary medicine, radiology and neonatology. I also co-lead the Bronchopulmonary Dysplasia Center at Cincinnati Children’s, where imaging research has been rapidly translated into clinical care and improved patient outcomes.

Research Interests

Hyperpolarized gas; pulmonary MRI; translational studies; image-guided pulmonary interventions

Academic Affiliation

Professor, UC Department of PediatricsUC Department of Radiology

Research Divisions

Pulmonary Medicine, Imaging, Fibrosis

Education

PhD: Washington University, St. Louis, MO, 2002.

Postdoctoral: Washington University, St. Louis, MO, 2004.

Publications

Neonates with Tracheomalacia Generate Auto-PEEP via Glottis Closure. Gunatilaka, CC; Hysinger, EB; Schuh, A; Gandhi, DB; Higano, NS; Xiao, Q; Hahn, AD; Fain, SB; Fleck, RJ; Woods, JC; et al. Chest. 2021.

Nanoparticle Delivery of STAT3 Alleviates Pulmonary Hypertension in a Mouse Model of Alveolar Capillary Dysplasia. Sun, F; Wang, G; Pradhan, A; Xu, K; Gomez-Arroyo, J; Zhang, Y; Kalin, GT; Deng, Z; Vagnozzi, RJ; He, H; et al. Circulation. 2021.

129Xe MRI as a measure of clinical disease severity for pediatric asthma. Lin, NY; Roach, DJ; Willmering, MM; Walkup, LL; Hossain, MM; Desirazu, P; Cleveland, ZI; Guilbert, TW; Woods, JC. Journal of Allergy and Clinical Immunology. 2021; 147:2146-2153.e1.

The Clinical Use of Lung MRI in Cystic Fibrosis: What, Now, How?. Dournes, G; Walkup, LL; Benlala, I; Willmering, MM; Macey, J; Bui, S; Laurent, F; Woods, JC. Chest. 2021; 159:2205-2217.

Quantitative Evaluation of Subglottic Stenosis Using Ultrashort Echo Time MRI in a Rabbit Model. Gandhi, DB; Rice, A; Gunatilaka, CC; Higano, NS; Fleck, RJ; de Alarcon, A; Hart, CK; Kuo, IC; Amin, RS; Woods, JC; et al. Laryngoscope. 2021; 131:E1971-E1979.

Effects of neonatal lung abnormalities on parenchymal R2 * estimates. Hahn, AD; Malkus, A; Kammerman, J; Higano, N; Walkup, LL; Woods, J; Fain, SB. Journal of Magnetic Resonance Imaging. 2021; 53:1853-1861.

Sensitive structural and functional measurements and 1-year pulmonary outcomes in pediatric cystic fibrosis. Willmering, MM; Roach, DJ; Kramer, EL; Walkup, LL; Cleveland, ZI; Woods, JC. Journal of Cystic Fibrosis. 2021; 20:533-539.

Quantitative inspiratory-expiratory chest CT to evaluate pulmonary involvement in pediatric hematopoietic stem-cell transplantation patients. Pennati, F; Walkup, LL; Chhabra, A; Towe, C; Myers, K; Aliverti, A; Woods, JC. Pediatric Pulmonology. 2021; 56:1026-1035.

Validating in vivo hyperpolarized 129 Xe diffusion MRI and diffusion morphometry in the mouse lung. Niedbalski, PJ; Cochran, AS; Freeman, MS; Guo, J; Fugate, EM; Davis, CB; Dahlke, J; Quirk, JD; Varisco, BM; Woods, JC; et al. Magnetic Resonance in Medicine. 2021; 85:2160-2173.

Subglottic Stenosis Position Affects Work of Breathing. Yang, MM; Higano, NS; Gunatilaka, CC; Hysinger, EB; Amin, RS; Woods, JC; Bates, AJ. Laryngoscope. 2021; 131:E1220-E1226.