Androgen Insensitivity Syndrome (AIS) is a condition that affects how the body grows and develops before birth and at puberty. People with AIS’s bodies make hormones called “androgens” at levels typical for boys and men. “Testosterone” is one type of androgen. However, their bodies do not respond to these hormones. Before birth, their bodies may develop typical features of a girl, or a boy, or a mixture of features.