Services & Specialties
Differences of Sex Development (DSD) Center

Guiding Families Through Differences of Sex Development With Expertise and Support

The Differences of Sex Development (DSD) team at Cincinnati Children’s uses an interdisciplinary approach with compassionate care to meet the complex needs of patients diagnosed with differences of sex development. Families often have many questions about diagnosis, treatment and what the future may look like. At Cincinnati Children’s, we help families understand you or your child’s condition and build a clear care plan together.

Our DSD Center cares for children, teens and young adults with conditions such as congenital adrenal hyperplasia, hypospadias, mixed gonadal dysgenesis, androgen insensitivity syndrome and ovotesticular DSD. Our interdisciplinary team includes experts in endocrinology, genetics, gynecology, urology, psychology, social work and bioethics. We work closely together to provide coordinated care that supports you or your child’s physical health, emotional well-being and long-term goals.

As active members of the DSD-Translational Research Network (DSD-TRN), we help improve DSD care nationwide. We also offer advanced genetic testing, fertility preservation research opportunities and personalized treatment planning designed around each patient and family.

Why Choose Cincinnati Children’s Differences of Sex Development Center?

  • Interdisciplinary care that brings specialists together to create one clear, coordinated plan for you/your child
  • Personalized treatment planning with shared decision-making that respects each family’s goals and values
  • Dedicated clinical coordination to schedule visits, gather records and guide families through every step of care
  • Advanced genetic testing and research access through our involvement in the national DSD-Translational Research Network

Specialized Care for Differences of Sex Development

National Leaders in DSD Care

Our specialists are recognized experts in the growing field of DSD care. Team members contribute to medical research, present at national and international conferences, and serve on professional committees focused on improving outcomes for children and young adults with DSD.

As members of the DSD-TRN, we work with centers across the U.S. to improve and standardize care for patients with DSD.

Coordinated Team-Based Care

People with DSD may need care from many specialists. Our interdisciplinary team includes experts in endocrinology, genetics, gynecology, urology, psychology, social work, child life and bioethics.

We meet regularly to review each patient’s needs and make sure families receive consistent recommendations from every provider. This coordinated approach helps families avoid confusion and creates a more seamless care experience.

Personalized Support for Every Family

There is no one-size-fits-all approach to DSD care. Our team develops a personalized care plan based on you/your child’s diagnosis, development, medical needs and family goals.

We also focus on whole-person care, including emotional health, coping support and long-term well-being. Families partner closely with our clinic coordinator, who helps schedule appointments, answer questions and connect families with support resources.

Advanced Testing and Research Opportunities

Our center offers access to advanced genetic testing supported by both a geneticist and a genetic counselor. Families receive guidance to better understand test results and how they may affect treatment decisions and future planning.

We are also one of a small number of centers nationally with a fertility preservation research protocol for individuals with DSD. Our involvement in research helps families access the latest care approaches and clinical opportunities when appropriate.

Support for Second Opinions

Families may seek a second opinion when facing complex decisions about DSD care. Our team provides thoughtful evaluations, education and guidance to help patients and families better understand their diagnosis and treatment options.

We work closely with referring physicians and families to ensure care recommendations are clear, coordinated and centered on each patients needs.

Services & Specialties
Differences of Sex Development (DSD) Center

Get expert, personalized care for differences of sex development (DSD) from a compassionate interdisciplinary team.

Children smiling.