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Pediatric Pericarditis

What is Pericarditis?

Pericarditis is an inflammation or infection of the pericardium, the thin sac (membrane) that surrounds the heart. There is a small amount of fluid between the inner and outer layers of the pericardium.

When the pericardium becomes inflamed, the amount of fluid between its two layers increases, compressing the heart and interfering with the heart's ability to work properly.

Causes of Pericarditis

Pericarditis is most likely to occur following surgery to repair congenital (present at birth) heart defects or acquired heart disease. However, other causes may include the following:

  • infection (viral, bacterial, fungal, parasitic)
  • chest trauma or injury
  • connective tissue disorders such as lupus

Signs and Symptoms of Pericarditis

The following are the most common symptoms of pericarditis. However, everyone experiences symptoms differently. Symptoms may include chest pain that:

  • can be felt especially behind the breastbone, and sometimes beneath the clavicle (collarbone), neck and left shoulder
  • is a sharp, piercing pain over the center or left side of the chest that increases as the child takes a deep breath

In addition to chest pain, other symptoms may include:

  • a low-grade fever
  • irritability
  • fatigue
  • loss of appetite
  • irregular heartbeat

Children may not be able to describe that they have "chest pain" or be able to explain how they feel. Sometimes, non-specific symptoms such as irritability, loss of appetite, or fatigue will be all that the child is able to express.

The symptoms of pericarditis may resemble other medical conditions or heart problems. Always consult your child's doctor for a diagnosis.

Diagnosis of Pericarditis

The doctor may have heard an abnormal heart sound called a rub, which occurs when there is irritation of the pericardial membranes. In addition to a complete medical history and physical exam, diagnosis of pericarditis may include:

  • blood tests (to evaluate the degree of inflammation)
  • chest X-ray - to produce images of internal tissues, bones and organs onto film
  • echocardiography (echo) - a procedure that evaluates the structure and function of the heart by using sound waves to produce a moving picture of the heart and heart valves

Treatment of Pericarditis

Specific treatment for pericarditis will be determined by your child's doctor based on:

  • your child's age, overall health, and medical history
  • extent of the disease
  • cause of the disease
  • tolerance for specific medications, procedures or therapies
  • expectations for the course of the disease
  • your opinion or preference

The goal of treatment for pericarditis is to determine and eliminate the cause of the disease.

Treatment may include:

  • medication (like analgesics and anti-inflammatory drugs)
  • aspiration (removal) of excess fluid
  • surgery

Last Updated 07/2025

Reviewed By Amy Donnellan, APP

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