Devonshire Research Lab
The Devonshire Lab is investigating for biomarkers of peanut allergy, particularly in the high-risk infant population. Ashley Devonshire, MD, MPH, is passionate about advancing the care of infants with food allergy through clinical practice and research. Her clinical and research interests are focused on early life strategies for food allergy prevention and improving the diagnostic and prognostic approach to patients with food allergy.
The lab is currently examining differential gene expression among infants at high risk for peanut allergy (Devonshire AL, et al. "Differential gene expression among infants at high-risk for peanut allergy." Journal of Allergy and Clinical Immunology. 143: AB83-AB83. 2019). The goal is to identify a biomarker of peanut allergy that may be detectable prior to clinical expression of the disease state. The use of molecular diagnostics to determine a transcriptomic signature of peanut allergy may also provide insight into the mechanisms underlying early loss of tolerance to foods.
Beginning Introduction to Allergens Early (BITE) Clinic
Ashley Devonshire, MD, MPH established the Beginning Introduction to Allergens Early (BITE) Clinic at Cincinnati Children’s, which includes an experimental pipeline for pediatric food allergy research housed within the Center for Autoimmune Genomics and Etiology and the Division of Allergy and Immunology.