Contributions of aberrant granule cell integration to the development of epilepsy
In adults, new brain cells are born daily in the hippocampus, a region that plays a role in common forms of epilepsy. Abnormal incorporation of these new cells into the brain may promote the development of the disease. We will investigate the role these new neurons play in the pathology, development and maintenance of epilepsy. By determining how normal brains become epileptic, we can begin to develop therapies to delay, halt and ultimately reverse the process.
2009-2014 − National Institutes of Health, 1R01-NS-062806.
SC Danzer, principal investigator.